
Holiday rentals in Santa Panagia
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Panagia
Guests agree: these stays are highly rated for location, cleanliness and more.

The Terrace over the Ancient Market of Ortigia
Charming home over the ancient market of Ortigia. This apartment offers a private terrace with stunning views of Ortigia and the sea. The modern and high-end design makes this accommodation unique. The Market is the most authentic place on the island of Ortigia, where the scents and flavors of yesteryear still find their perfect expression today. The apartment offers a bedroom with balcony and en-suite bathroom, a large living room with balcony, an open concept kitchen and an additional bathroom

Shati Luxury •Private Pool•Sea View•Walk to Beach
Private heated pool 30°C, all year round. Just a few steps from a pristine white sandy beach Sea view and total privacy. Signature design and refined luxury. An architectural retreat immersed in tropical greenery overlooking the sea. Iconic design, comfort and top-level services. Premium sleep with toppers and a curated pillow menu. Breathtaking sea views and refined finishes. On request: private chef, daily housekeeper, babysitting and tailor-made experiences Signature design by C. Calvagna.

Penthouse Lady Packard
Lady Packard’s Penthouse is a stunningly elegant, spacious and comfortable house with four levels, all above ground because of the sloping, pedestrian street on which it is built. Free parking is just steps away. The location is ideal, peaceful with amazing views, and just a few minutes’ walk from the Cathedral at the city's center. The house sleeps 6 adults in 3 separate bedrooms. Perfect for a family holiday or a friends getaway, the common spaces comfortably accommodate everyone at once.

Casa Salgiò
Accogliente e moderno appartamento alle porte di Siracusa, a soli 10 minuti in auto dal centro storico ed in una zona ben servita. L'appartamento, completamente ristrutturato, è composto da una zona living con divano letto matrimoniale, un cucinotto attrezzato, una camera da letto, una piccola stanza con un posto letto, bagno con doccia, un ripostiglio e di una zona lavanderia. Il living e la camera da letto affacciano su una veranda dalla quale è possibile vedere scorci di mare e l'Etna.

One step to Ortigia! Bicycles & Balcony
Bright and stylish renovated flat just steps from the city center and Ortigia—you can walk to all the must-see spots with ease. Cozy and welcoming, it’s the perfect home base for your holiday in Sicily! ☀️ Sunny balcony for relaxing moments en plein air 🚲 FREE bicycles available throughout your entire stay 🚗 Hassle-free street parking – and it’s free 24/7! We also have two more apartments in the same building—check out my profile to discover them and read our glowing 5-star reviews!

Sea-View Loft. Stylish, Spacious and Comfortable
Experience the magic of Ortigia in this elegant, thoughtfully designed 80m² apartment that blends charm, comfort, and relaxation. Ideal for couples or small groups, it is located just steps from the island’s most iconic sights. Enjoy a stunning sea view balcony, a bright living area complete with a sofa bed, a fully equipped kitchen, a cozy bedroom, and two modern bathrooms. Amenities include fast WiFi, A/C, and heating. For your convenience, the building is served by an elevator.

Luce e Relax: Grande Open Space su Giardino
Situato in un’ala riservata della villa con ingresso indipendente, questo open space di 95 mq unisce raffinatezza e modernità. Le ampie vetrate inondano di luce naturale gli ambienti, mentre l’arredamento definisce con naturalezza le diverse aree. Un perfetto equilibrio tra design, comfort e natura: gli spazi si fondono armoniosamente con il giardino, creando relax e privacy. Per motivi di sicurezza e comfort la struttura ospita bambini solo dai 10 anni compiuti in su.

Casa dei Leoni – Balcony on Piazza Duomo | Ortigia
Wake up overlooking Piazza Duomo in the heart of Ortigia. Casa dei Leoni, a real home in the very heart of Ortigia. Overlooking Piazza Minerva, just a few steps from the Cathedral, this elegant apartment blends the charm of Sicilian history with modern comfort. Bright interiors, a private balcony with an open view, and carefully curated spaces make Casa dei Leoni the ideal place for guests seeking beauty, peace, and an authentic stay in Syracuse’s historic center.

Agàpe Ortigia
Agàpe Ortigia un alloggio creato con Amore nella magica isola di Ortigia, in pieno centro storico a due passi dal Duomo ed i maggiori siti d’interesse. La camera indipendente é ampia e spaziosa, dispone di un letto matrimoniale, tv, Wi-Fi gratuito, angolo tisane e caffè ma la particolarità di questo alloggio a parte l’arredamento è il bagno che oltre ad avere i servizi principali offre una grande vasca interrata dove è possibile rilassarsi.

Re Carlo - Ortigia Luxury Suite
Located in the heart of Ortigia, in the amazing Duomo Square in Siracusa, Re Carlo – Duomo Luxury Suite is an exclusive suite that combines elegance, comfort, and history. Ideal for couples or small families, it offers a refined stay in one of Sicily’s most charming locations. With carefully designed spaces, a private entrance, and an exclusive outdoor area, it ensures a unique experience in the historic center of Syracuse.

Rua 39 fine apartmente 6
Welcome to Rua Riad, the perfect base to explore Ortigia. This elegant riad-style home blends Mediterranean charm with modern comforts and features a private pool for pure relaxation. Ideal for families or friends, it offers refined spaces and an intimate atmosphere surrounded by sea, culture, and timeless beauty. Note: due to stairs, it may not be suitable for small children or guests with mobility issues.

Comodo appartamento con posto auto riservato
Apartment in an area well served by shops, supermarkets, bars, pizzerias, tobacconists, newsagents, bakery, bank and a characteristic street market with fish, fruit and typical products. Well equipped kitchen. Easily accessible by car and equipped with a reserved parking space inside a fenced condominium courtyard. The apartment is equipped with books and various touristic documentation on Sicily.
Popular amenities for Santa Panagia holiday rentals
Other great holiday rentals in Santa Panagia

Flat Pi Greco/ Easy parking/1km from Ortigia

Siracusa Suite, AC + Wi-Fi + Free Private Parking

Febo House by Wonderful Italy

Palazzo GiuFa

Charming 3 bedroom house in Ortigia by Cala Rossa

Casa Sirokos

Stefano's house

Siracusa Ortigia Circe sul Mare
Destinations to explore
- Fontane Bianche Beach
- Calamosche Beach
- Etna Park
- Etnaland
- Castello Ursino
- Piano Provenzana
- Teatro Massimo Bellini
- Fondachello Village
- Castello Maniace
- Castello di Donnafugata
- Greek Theatre of Syracuse
- Villa Bellini
- Sampieri Beach
- Oasi Del Gelsomineto
- Isola delle Correnti
- Fishmarket
- Nature reserve of Vendicari
- Museo Emilio Greco
- Museo Archeologico Regionale Paolo Orsi
- Temple of Apollo
- Spiaggia Vendicari
- Necropolis of Pantalica
- Monastery of San Nicolò l'Arena
- Noto Cathedral





