Holiday rentals in Santee River

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Top-rated holiday rentals in Santee River

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Top guest favourite
A spacious living area features a light gray sectional sofa and a comfortable armchair. A wooden coffee table sits in the center, adorned with decorative elements. A television is mounted above a gas fireplace, and soft natural light fills the space through nearby windows.
Apartment in Moncks Corner
4.98 out of 5 average rating, 42 reviews

Updated 2BR condo with balcony

Enjoy a getaway to this relaxing and peaceful second-floor condo unit in Moncks Corner. You will feel right at home with a fully equipped kitchen, tasteful decor, and in-unit washer & dryer. Conveniently located in town and walking distance to many stores, restaurants and the new Hidden Cove Marina. Also boat trailer parking is available if needed. After a day of exploring, unwind on the private balcony or kick back and enjoy streaming on one of 3 smart TVs. Community pool is open seasonally.

Guest favourite
Home in Kingstree
4.94 out of 5 average rating, 122 reviews

magical 1840s farm house getaway

Centuries old country estate with magical ambiance, art and antiques, beautiful views and wrap around porches. Relax in the hot tub in your own private oasis or gather with friends and family around the fire pit. Multiple bird feeders and grand live oaks, magnolias, fruit trees and a kitchen garden. Chefs kitchen will be stocked with fresh eggs, herbs and seasonal veggies. Sit and sip on the porch while enjoying the views of farmer's field and listing to the moos of the cows. Groups welcome!

Top guest favourite
An airy loft space features a suspended wooden swing, inviting relaxation under the high, timbered ceilings. Natural light streams through large windows, illuminating cozy furnishings including a bed and a dining area with a wooden table. Unique decor elements enhance the overall character.
Guest house in Summerville
4.98 out of 5 average rating, 726 reviews

★Delightful guest house near historic plantations★

Nestled in the Historic Plantation District between Summerville & Charleston, our timberframe "bunkhouse" offers privacy, comfort & convenience. This 850+ sq ft retreat includes full kitchen & bath, 2 dbl beds, twin bed & plenty of living space. There's a private entrance, so come & go as you please (we're right next door if you need us). Minutes from Middleton Place, Drayton Hall & Magnolia Gardens, an easy drive to dntn Charleston, historic S'ville, beaches & golf courses. *Now with WiFi*

Guest favourite
The kitchen area features wooden walls and a contrasting white tiled backsplash. Stainless steel appliances, including a refrigerator and oven, are present. A dining table with place settings sits nearby, while natural light filters through windows, enhancing the space's functionality.
Tiny home in Saint Stephen
4.94 out of 5 average rating, 18 reviews

The Boat Shed

This can be your quiet getaway at the duck farm as you relax in the Boat Shed beside the pond. You will have the entire house to yourself complete with kitchen, living space, bedroom, full bath with shower. There is a loft on each end of the tiny house best suited for children and teens. The front porch faces the pond with four acres & ducks. Canoes are available fully equipped with life jackets and paddles. Swimming is allowed with adult supervision, including a rope swing and zip line.

Guest favourite
A scenic view of the ocean is presented, with a sandy beach visible in the distance. Palm trees frame the foreground, while a pool area and adjacent building are situated nearby. The boardwalk extends toward the water, enhancing the coastal atmosphere.
Apartment in Isle of Palms
4.83 out of 5 average rating, 468 reviews

Oceanfront Top Floor ☼ Beautiful Panoramic View!

Cozy third floor condo with unbeatable ocean views. This unit is top floor, center building which means panoramic views of the beach and ocean. Great location in the heart of Isle of Palms, with easy access to shopping, dining and entertainment. Open floor plan with full kitchen. Views of the ocean from the balcony, living room, and even the kitchen. Enjoy a cup of coffee as the sun rises or savor a glass of wine and take in an amazing sunset while listening to the waves of the ocean.

Guest favourite
A well-appointed sleeping area is featured, showcasing a spacious bed dressed in a light coverlet. A cozy armchair sits nearby, complemented by a decorative wall sign and a serene landscape painting. Natural light enters through a sheer white curtain by the window.
Tiny home in Moncks Corner
4.92 out of 5 average rating, 158 reviews

Tiny House studio stay in Moncks Corner

The tiny house is located in our backyard in a small town, Moncks Corner, South Carolina. As you enter the house, you will notice that it is small but it has everything you will need to enjoy your stay! A kitchen to cook in, a table to eat or work at, a nice place to shower and sleep - all in the same room. It is small yet very comfortable and welcoming! We operate off of well water. If you are not used to well water, the smell can sometimes be surprising. Please note: the water is safe.

Guest favourite
A comfortable gray couch with green accent pillows is positioned near a large window. A small table is visible beside the couch, while a floor lamp provides soft illumination. A potted plant adds a touch of greenery to the space, enhancing the inviting atmosphere.
Loft in Summerville
4.91 out of 5 average rating, 396 reviews

White Pickett District Loft

Welcome to our charming White Pickett District loft nestled in the heart of historic downtown Summerville! This cozy retreat offers a private one bedroom, one bath with kitchenette, perfect for couples or solo travelers looking to explore the beauty of South Carolina. WPD is just steps away from the town’s rich history and culture. Whether you’re here for a weekend getaway or an extended stay, WPD offers the perfect blend of comfort, convenience & charm for unforgettable experience!

Top guest favourite
The entrance of the cabin features a modern black exterior with a circular welcome mat and a stylish door showcasing large glass panes. Potted white flowers add a touch of nature, while an outdoor chair invites relaxation amidst the greenery of surrounding trees.
Farm stay in Georgetown
5 out of 5 average rating, 35 reviews

Lo & Billy’s Place a historic 1940s Newlywed Cabin

This romantic cabin located on our small farm just outside of town in the country offers a history all its own. Lo was Billy’s nickname for Lorene Ella. Lo & Billy got married in the 1950s and lived here. Renovated after meeting Lo and hearing her stories. We pay homage to the rich history of Georgetown and the Southerners that have called Lo & Billy’s Place home. Heavy on coziness & design. Full kitchen; good coffee; & comfy queen bed w/high end linens. The perfect escape.

Top guest favourite
The exterior of the villa is shown, featuring a light-colored stucco façade contrasted by large windows. Surrounding landscaped areas include planters with vibrant greenery and flowers. A gravel pathway leads to the entrance, framed by the natural beauty of trees in the background.
Home in Summerville
4.93 out of 5 average rating, 133 reviews

Guest House/Villa

Enjoy your stay at this immaculately designed new build Villa. Located on a family property surrounded by 2 acres of trees, in a quiet rural neighborhood. Lots of privacy, peace and quiet, yet only 5 minutes from restaurants and stores. 15 minutes from Downtown Summerville, 40 minutes from Charleston and various coastal attractions. The villa is separate from main house and has no shared space other than the driveway. NO smoking, No pets. Laundry service available for long stays.

Guest favourite
A one-story red brick building is presented with a neatly manicured lawn and bordered by small, well-maintained shrubs. Large windows are visible, allowing natural light to brighten the interior. A concrete driveway leads to the entrance, flanked by steps that lead to the front door.
Flat in Lake City
4.91 out of 5 average rating, 253 reviews

#4 Away from Home, Upgrade the Space, Not the Rate

Located on Main Street in a family home that has been updated to be like brand new. Apartment 4 has one bedroom with door, a private entrance, bath and dressing area, micro-kitchen, living & dining combination. Amenities include SPECTRUM & ROKU TV, in B.R. and L.R., wifi, front door parking, in room fresh brewed coffee (Cafe Valet) and Wind River Salon Products. Downtown Lake City is an easy one mile walk along Main Street. 1/2 way from New York to Miami. Hablamos Espanol.

Top guest favourite
A field of blooming yellow flowers is displayed in the foreground, with delicate petals and green stems. In the background, a white farmhouse is visible, providing a serene country setting. The scene captures the tranquility of the flower field adjacent to the cottage.
Tiny home in Moncks Corner
4.95 out of 5 average rating, 136 reviews

The Goose Cottage at Wild Goose Flower Farm

Located next to the family farmhouse at Wild Goose Flower Farm, The Goose Cottage was designed to immerse guests in our calm and peaceful country life. We are located 15 minutes from the hearts of Cane Bay, Nexton and Exit 194 on I-26, and 45 minutes from Downtown Charleston. Two can sleep in the queen size bed but the sofa also extends into a queen-sized sleeper. Please reach out with further questions or if you would like to inquire about an extended stay.

Top guest favourite
A warm living space is highlighted by a comfortable brown sofa and accent pillows. A sleek coffee table sits on a patterned area rug, while two decorative stools provide additional seating. The bedroom area features a queen-sized bed with soft linens and bedside lamps, enhanced by natural light from nearby windows.
Guest house in Hanahan
4.99 out of 5 average rating, 230 reviews

The Violet Villa w/no cleaning fee

Come enjoy this beautiful private guesthouse conveniently located minutes from shopping, food, venues and the beach. When you arrive, we have cooled bottled water to quench your thirst. As the evening sets, stroll the nature trail and catch the sunset from the neighborhood dock. A 70” smart tv awaits your return so you can watch your favorite movies (without sharing an armrest). Come relax! This is a vacation for you

Popular amenities for Santee River holiday rentals