
Holiday rentals in Santiago
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Top-rated holiday rentals in Santiago
Guests agree: these stays are highly rated for location, cleanliness and more.

Salamanca Loft
Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

Comfortable and safe apartment in downtown Santiago
Family-friendly apartment in the centre of Santiago — comfortable, safe and fully equipped Enjoy a prime location right in the heart of Santiago de Veraguas, just a short walk from the cathedral, the municipal park and the main avenue. Everything you need is within walking distance: supermarkets, pharmacies, banks, shops, restaurants and public transport. Ideal for families, professionals, business travellers, or people visiting the city for official purposes or events.

Casa Valle de Barbarena
Excelente ubicación cerca del centro a tan solo 2 kilómetros un lugar tranquilo. Cerca del mall Casa de dos cuartos y dos camas Doble un sofá cama Espacio de Lavandería o depósito de almacenamiento Nice location near the city 2 km Away from the center of Santiago close to the mall It has 2 rooms each with a doble bed and a sofa bed in the living room Laundry room with nice space to bring in your bike or any thing that you will like to store inside the house.

Cozy Home El Espino | Pool and Family Atmosphere
Take the whole family to this fantastic place with spaces to rest and enjoy. Cozy Home in El Espino is inside a private residential complex with a security gate: safe, quiet and family atmosphere, surrounded by nature. Enjoy the social area with terrace and 3-level pool. A few metres from the Interamericana. The house has 3 bedrooms (2 with A/C) and 2 bathrooms; one with hot water. Fully equipped kitchen. Rate for 4 (max. $15/person extra) 6) Pets allowed for a fee.

Casa a minutos de Santiago, U Latina, HospChichoF.
Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, shops, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.

Santiago city, home w/ spacious living & office
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Yary's Little House
Mi alojamiento es especial por su Comodidad y Ubicación. Este alojamiento es perfecto para disfrutar en viajes de trabajo, en grupo o relajarte en familia. Ubicado estratégicamente en la entrada de la ciudad de Santiago, te permite estar cerca de todo: supermercados, restaurantes, centros comerciales y más. 🏡 El espacio Disfruta de un ambiente cómodo, moderno y acogedor que hará de tu estadía una experiencia inolvidable.

Studio Hotel Gran David
This studio is located behind the Hotel Gran David, which is located in a very convenient location (Carretera Panamericana). However, this studio is located on a very quiet area at the back part of the hotel. Although the studio has an independent entrance to that of the hotel, you can still use all the amenities of the hotel (swimming pool and gym), and have easy access to the hotel's two restaurants, pool bar and bar.

Departamento 3E - BEST place in town.
Departamento accesible en el centro de Santiago, ubicado a 300m de la terminal de Transporte y a poca distancia de supermercados y negocios. Con buena distribución del espacio, frescos e iluminados y con todos los servicios básicos. Los apartamentos brindan un balance armonioso en medio del va y ven característico del centro, perfecto para estadías de amigos, profesionales, parejas y familia.

d'rosas apartments 3PB
Discover comfort in our cozy accommodation in the heart of Santiago, Veraguas. Just a 5-minute walk from the city center, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring the local culture and resting after a day of adventures. We look forward to seeing you!

Espinosa Bungalow
This cabin is surrounded by vegetation, behind it passes a clean water creek in the middle of the courtyard, which can be crossed by a bridge, it is spacious, it is a 2-minute walk from the Los Sabalos River, 25 minutes from Playa Reina, Mariato, 10 minutes from downtown Atalaya. There are paved streets, drinking water.

2 bedroom house in Santiago
centric, well located, walking distance to downtown. Near the Panama Canal Museum, park Juan Demostenes Arosemana, and the Santiago Cathedral Juan Pablo Apostol. A few meters from central avenue.
Popular amenities for Santiago holiday rentals
Other great holiday rentals in Santiago

2A Apartment

d'rosas apartments 6PA

Private room in Santiago

Wellbeing Rentals

Departamento 2E - BEST place in town.

Casa Pueblo - Ocú

Double Room - Hotel Plaza Los Tucanes

Full room with private bathroom, residential
Frequently Asked Questions
How much does it cost to stay in house rentals in Santiago?
Experience the best of Santiago with our house rentals, starting at about $30 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.
Are there pet-friendly vacation rentals in Santiago?
Four-legged friends are welcome in Santiago. Choose from more than 20 vacation rentals for guests traveling with pets.
Are there vacation rentals with a dedicated workspace in Santiago?
Yes! Work meets play with ease at over 20 vacation rentals in Santiago featuring dedicated workspaces. Stay connected and productive in your home away from home.
Do house rentals in Santiago have air conditioning?
Absolutely! We offer over 20 house rentals with air conditioning in Santiago. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Santiago have a kitchen?
Absolutely! We offer over 20 house rentals with a kitchen in Santiago. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Santiago have wifi?
Absolutely! We offer over 20 house rentals with wifi in Santiago. Enjoy a tailored experience with all the comforts you desire.
Do house rentals in Santiago have free parking?
Absolutely! We offer over 20 house rentals with free parking in Santiago. Enjoy a tailored experience with all the comforts you desire.
What are the most popular amenities for House Rentals in Santiago?
Enhance your stay in our House Rentals with the most popular amenities: over 20 homes with a kitchen, over 20 homes with air conditioning, over 20 homes with wifi, over 20 homes with free parking, and more. Indulge in the ultimate retreat, tailored to your preferences.
Quick stats about holiday rentals in Santiago

Total holiday rentals
Explore 60 holiday rentals in Santiago

Nightly prices starting at
Santiago holiday rentals start at £15 per night before taxes and fees

Verified guest reviews
Over 700 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
50 of Santiago holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santiago rentals

4.7 Average rating
Santiago stays receive an average rating of 4.7 out of 5 from guests
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