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Holiday rentals in Santiago

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Top-rated holiday rentals in Santiago

Guests agree: these stays are highly rated for location, cleanliness and more.

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A bright and airy room features two full-size beds with crisp white linens and decorative pillows. A wooden dining table with four chairs is positioned nearby. Fresh towels are neatly arranged on the beds. A small kitchenette is subtly integrated into the space.
Flat in Los Canelos
4.71 out of 5 average rating, 45 reviews

Salamanca Loft

Este hermoso apartamento esta ubicado en el centro de todo Panamá en la hermosa provincia de Herrera, vía interamericana, a pocos minutos de varias ciudades como Chitré, Aguadulce y Santiago. En un ambiente tranquilo, rodeado de árboles. Si corren con suerte podrán observar desde lejos las hermosas iguanas que se pasean por las ramas mas altas. Pueden apreciar al caer la tarde una hermosa puesta del sol. Justo al frente, hay cafetería, también hay pizzerías a domicilio y restaurantes.

Guest favourite
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.92 out of 5 average rating, 24 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Superhost
Home in Santiago
4.95 out of 5 average rating, 20 reviews

Casa a minutos de Santiago, U Latina, HospChichoF.

Spacious, comfortable and fully equipped house in a strategic location in Santiago. Perfect for all types of guests: families, business travelers, students, people coming to medical appointments or those looking for a quiet and accessible space. The house is located very close to Dr. Chicho Fábrega Hospital, Clínica Norte, U.Latina, Oxford School, shops, supermarkets, pharmacy, restaurants, and minutes from downtown Santiago. A safe place for short and long stays.

Top guest favourite
Home in Canto del Llano
5 out of 5 average rating, 11 reviews

Peaceful home w/ spacious living & office area

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

An outdoor bathroom is enclosed by bamboo walls and natural stone, featuring a wooden basin and a unique circular shower area. Smooth pebbles create a textured border around the space, enhancing its connection to nature.
Cabin in Santa Fe
4.64 out of 5 average rating, 28 reviews

Treehouse

Come relax in this unique logging overlooking the Santa Maria's river. Immerse yourself in nature while having the comfort of quality beds and furniture. Ideal to spend a few nights when you are traveling or a long stay if you feel like reconnecting with what is essential. This beautiful habitat will rock you into the sounds and smells of Panama's mountain's soft nature. Outside kitchen and bathroom. Optional relax massage. Two queen size bed.

A spacious studio is presented, featuring a comfortable sofa and a queen bed with an elegant headboard. A flat-screen TV is mounted on the wall opposite. A small table and chairs are arranged near the sofa, providing a cozy seating area within the bright space.
Flat in Santiago
5 out of 5 average rating, 4 reviews

Studio Hotel Gran David

This studio is located behind the Hotel Gran David, which is located in a very convenient location (Carretera Panamericana). However, this studio is located on a very quiet area at the back part of the hotel. Although the studio has an independent entrance to that of the hotel, you can still use all the amenities of the hotel (swimming pool and gym), and have easy access to the hotel's two restaurants, pool bar and bar.

A spacious living area is presented with a light-toned sofa adjacent to large windows, providing natural light. A metal shelving unit adorned with plants stands in the center, complemented by a simple round mirror on the wall. A wooden table and chair add functionality to the space.
Apartment in Santiago
4.72 out of 5 average rating, 18 reviews

Apartment 2A

Accessible apartment in the center of Santiago, located 300 meters from the Transportation terminal and walking distance to supermarkets and businesses. With good distribution of space, fresh and illuminated and with all basic amenities. The apartments provide a harmonious balance in the midst of the characteristic go and see of the center, perfect for stays of families, friends, professionals, couples.

Guest favourite
Farm stay in Santa Fe
4.9 out of 5 average rating, 306 reviews

Sun Cabin at Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

A small dining area is featured with a round table and two folding chairs. Large windows offer views of lush greenery outside, while sheer white curtains partially filter natural light.
Flat in Santiago
4.88 out of 5 average rating, 8 reviews

d'rosas apartamentos 3PB

Discover the comfort in our cozy home in the heart of Santiago, Veraguas. Just a 5 minute walk from downtown, you'll enjoy a well-equipped space that includes all the necessary amenities for a relaxing stay. Ideal for exploring local culture and resting after a day of adventure. We look forward to seeing you!

Guest favourite
Flat in Santiago
4.86 out of 5 average rating, 7 reviews

Accommodation in Santiago Centro

Enjoy the easy access to everything from this perfectly located accommodation, in the center of Santiago 2 minutes from the cathedral church, park, and the central Ave. Fresh and comfortable on the ground floor of a property a large terrace with access to the patio surrounded by nature.

Guest favourite
A modest exterior view features a white building with dark windows and a welcoming black door. Lush greenery surrounds the entrance, and well-maintained stone pathways lead to the door, highlighting the peaceful outdoor setting.
Home in Santiago
4.86 out of 5 average rating, 21 reviews

2 bedroom house in Santiago

centric, well located, walking distance to downtown. Near the Panama Canal Museum, park Juan Demostenes Arosemana, and the Santiago Cathedral Juan Pablo Apostol. A few meters from central avenue.

A large round mirror is mounted on a wall featuring elegant marble patterns, reflecting a warm wood accent. A small green plant is positioned nearby, adding a touch of nature to the space. The background reveals hints of a softly lit kitchen area.
Home in Santiago
4.53 out of 5 average rating, 15 reviews

Family Hosting

Hospedaje básico, 1 recamara, cuarto estudio, seguro y tranquilo para viajeros, a 5 minutos del centro de la Ciudad para que puedas descansar. Casa remodelada en un 70%

Popular amenities for Santiago holiday rentals

Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Santiago?

    Yes! Work meets play with ease at over 20 vacation rentals in Santiago featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Do house rentals in Santiago have air conditioning?

    Absolutely! We offer over 20 house rentals with air conditioning in Santiago. Enjoy a tailored experience with all the comforts you desire.

  • Are there family-friendly vacation rentals in Santiago?

    Santiago has more than 20 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

  • What are the most popular amenities for House Rentals in Santiago?

    Enhance your stay in our House Rentals with the most popular amenities: over 20 homes with free parking, over 20 homes with wifi, over 20 homes with a kitchen, over 20 homes with air conditioning, and more. Indulge in the ultimate retreat, tailored to your preferences.

  • Do house rentals in Santiago have wifi?

    Absolutely! We offer over 20 house rentals with wifi in Santiago. Enjoy a tailored experience with all the comforts you desire.

  • Are there pet-friendly vacation rentals in Santiago?

    Four-legged friends are welcome in Santiago. Choose from more than 20 vacation rentals for guests traveling with pets.

  • How much does it cost to stay in house rentals in Santiago?

    Experience the best of Santiago with our house rentals, starting at about $10 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Do house rentals in Santiago have a kitchen?

    Absolutely! We offer over 20 house rentals with a kitchen in Santiago. Enjoy a tailored experience with all the comforts you desire.

Quick stats about holiday rentals in Santiago

  • Total holiday rentals

    Explore 60 holiday rentals in Santiago

  • Nightly prices starting at

    Santiago holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 600 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 30 rentals that welcome pets

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    40 of Santiago holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santiago rentals

  • 4.7 Average rating

    Santiago stays receive an average rating of 4.7 out of 5 from guests

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