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Mansion holiday rentals in Santo Domingo

Find and book unique mansions on Airbnb

Top-rated mansion rentals in Santo Domingo

Guests agree: these mansions are highly rated for location, cleanliness and more.

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Top guest favourite
An outdoor patio area is featured with a wooden dining table set for six, accompanied by lounge chairs. A sparkling pool is visible in the background, surrounded by lush greenery and the striking architectural elements of the home, including an aged stone wall.
Villa in Ciudad Colonial
4.94 out of 5 average rating, 386 reviews

Casa Pantheon Luxury Colonial House

Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED

Guest favourite
A scenic view from the terrace showcases a blend of modern and classical architecture, with a large domed structure in the foreground and high-rise buildings in the background. The ocean glimmers in the distance under a clear blue sky.
Apartment in Gazcue
4.88 out of 5 average rating, 197 reviews

Beautiful Modern Penthouse close to Zona Colonial.

Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 5 smart TVs and much more. Smart lock for easy check-in.

Top guest favourite
A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.
Home in Los Prados
4.99 out of 5 average rating, 147 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Guest favourite
The three-story villa is surrounded by lush greenery, featuring a large pool with a relaxing waterfall. Loungers are positioned around the pool area, with a private basketball court nearby. The bright blue sky complements the serene atmosphere of this tropical retreat.
Villa
4.85 out of 5 average rating, 109 reviews

VillaRosario-Resort-Poolhothub NearAirport & Beach

¡Escápate a nuestra lujosa villa tropical en Santo Domingo Este carretera Samana , República Dominicana! Ideal para familias, amigos y reuniones, este amplio refugio cuenta con 6 habitaciones, 12 camas y 3 piso, acogedora iluminación ambiental. Sal al exterior y sumérgete en un paraíso exuberante, disfruta de delicias orgánicas del jardín de frutas y relájate junto a la piscina privada con una relajante cascada y jacuzzi. Los entusiastas del deporte adorarán la cancha de baloncesto privada.

Guest favourite
Home in Los Frailes
4.85 out of 5 average rating, 47 reviews

'Casa de Papel' Luxurious VILLA

Discover the ultimate party getaway at Villa Fiesta Oasis! This luxurious 4-bedroom villa offers everything you need for an unforgettable stay: a sparkling pool, a relaxing jacuzzi, and ample space for entertaining. Located just minutes from the airport, convenience and comfort come together in this stunning retreat. Whether you're hosting a celebration or simply seeking a relaxing escape, House of Cards (Casa de Papel) is your perfect destination. Experience the best of Santo Domingo!

Top guest favourite
A view from the entrance showcases a stylish living area. A vibrant yellow chair complements a dark green sofa, while a round wooden coffee table sits in the center. Natural light streams in through large windows with a soft blue wall framing the scene.
Flat in Ciudad Colonial
4.88 out of 5 average rating, 101 reviews

Eclectic,Spacious,4BR Penthouse

Air conditioner is fixed in the living room! Completely renovated Colonial Apartment-Penthouse on Famous El Conde St . in the heart of Zona Colonial. M-lily Mattresses ,Luxury Bedding Lacoste , CK ,RL Brand new Fully equipped Chef Kitchen with top brands cooking tools Self check-in Laundry&market service available Gym next door , day pass $2 Safest location Politur HQ across street Shampoo &bodywash Bright,Airy,Fresh Latest tech lighting crib XLL Balcony 24/7 electric kit

Guest favourite
Home in Ciudad Colonial
4.95 out of 5 average rating, 43 reviews

Casa del Orfebre circa 1525

Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.

Guest favourite
Flat in Santo Domingo
4.89 out of 5 average rating, 75 reviews

Luxury Rooftop Penthouse|Chef Experience|Sleeps 10

Indulge in a luxury rooftop lifestyle with this stunning penthouse, complete with a private jacuzzi, lounge, and panoramic city views. Elevate your stay with a private chef experience available upon request, creating unforgettable dining moments in total privacy. Ideal for families and groups, this expansive residence comfortably accommodates up to 10 guests while maintaining privacy, elegance, and high standards Note: Private chef service must be arranged in advance.

Superhost
The exterior of the villa displays a spacious backyard with a well-maintained lawn and a swimming pool. Palm trees provide shade, while a covered seating area is positioned nearby. The two-story villa features a light-colored facade and large windows that enhance the openness of the space.
Chalet in Santo Domingo Este
4.88 out of 5 average rating, 136 reviews

VillaFranciscoRD, (15min Aeropuerto)Chef Incluido.

Quieres desconectar y disfrutar de la naturaleza? Este alojamiento es ideal para pasar un fin de semana con toda la familia, con una decoración moderna y acogedora que te permitira sentirte como en casa. Disfruta de uno de los mejores espacios al aire libre en la piscina, donde puedes prepararte una deliciosa barbacoa mientras te relajas y disfrutas del sol . A 15 minutos del aeropuerto de las Americas y a 12 minutos del centro de la ciudad.

Superhost
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5.0 out of 5 average rating, 61 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Guest favourite
A jacuzzi is showcased on a private terrace, with water reflecting natural light. A vibrant mural of waterfalls and greenery serves as a striking backdrop, enhancing the outdoor setting. Comfortable seating options are available nearby, surrounded by a wooden deck.
Flat in Santo Domingo Este
4.89 out of 5 average rating, 239 reviews

Paradise Luxury Penthouse With Private Jacuzzi

Apartamento cómodo y limpio en una area segura. Ubicado en la avenida España. A solo 20 minutos del aeropuerto, 25 minutos de la playa boca chica y 15 mins de la zona colonial. Cuenta con multiple opciones de restaurantes, bars, mixers, supermercado, farmacias, bodegas o colmados y mas a solo minutos. Aire acondicionado en cada dormitorio siempre que haya energía eléctrica, de no haber contamos con abanicos movidos por un inversor.

Superhost
Flat in Ensanche Quiqueya
4.86 out of 5 average rating, 124 reviews

Penthouse 5BR | Billar | City View | Terrace Top

Experience a modern 3-level penthouse in the heart of Evaristo Morales. With 5 bedrooms, spacious living areas, a private terrace, and elegant design, it’s ideal for families and groups. Steps from Gold’s Gym, Smart Fit, supermarkets, restaurants, and banks, and minutes from BlueMall, Acropolis, and Ágora Mall. Enjoy comfort, style, and the best location in Santo Domingo.

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