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House holiday rentals in Santo Domingo

Find and book unique houses on Airbnb

Quick stats about house rentals in Santo Domingo

  • Total holiday rentals

    Explore 490 holiday rentals in Santo Domingo

  • Nightly prices starting at

    Santo Domingo holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 13,190 verified reviews to help you choose

  • Family-friendly holiday rentals

    190 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 120 rentals that welcome pets

  • Holiday rentals with a pool

    100 properties feature pools

  • Rentals with dedicated workspaces

    180 properties have a dedicated workspace

  • Wifi availability

    460 of Santo Domingo holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santo Domingo rentals

  • 4.7 Average rating

    Santo Domingo stays receive an average rating of 4.7 out of 5 from guests

Top-rated house rentals in Santo Domingo

Guests agree: these houses are highly rated for location, cleanliness and more.

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Top guest favourite
Home in Los Frailes
4.95 out of 5 average rating, 66 reviews

Private Home, Hot Water, Security, Pool and Patio

We offer the best space with the best amenities to spend time with family and friends or celebrate your birthday in RD: • Hot water🛁 • Visitors are allowed🫂 • Air Conditioning in all areas❄️ • Dryer machine 👕👖 • Las Americas mins away from Av. España, SDQ airport, beaches, retail stores, banks, malls, restaurants, and clubs ✈️🏖️🛍️🏧🍻 • Private pool, spacious backyard, patio furniture, dominos & BBQ 🏊‍♀️🥩 • Perfect for families, couples, & friends 👣 • 5G Wifi 🛜 • Private bedrooms 🛏️

Top guest favourite
A spacious living area features a light-colored sofa adorned with decorative pillows. A coffee table with floral arrangements complements two blue accent chairs nearby. Large windows allow natural light to fill the room, enhancing the bright, airy atmosphere.
Home in Los Prados
4.99 out of 5 average rating, 138 reviews

Casa Serena: cozy, modern, spacious and peaceful

Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Top guest favourite
A serene outdoor space features a small pool surrounded by light-colored stone steps. Green walls and natural light are provided through a skylight, enhancing the ambience. Tropical plants frame the area, contributing to a private and refreshing atmosphere.
Home in Ciudad Colonial
4.89 out of 5 average rating, 143 reviews

Colorful Caribbean house in the Zona Colonial

Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Superhost
A modern living area is presented with white leather seating and a glass coffee table. Accent lights illuminate built-in shelving displaying decorative items. A fan and a television are positioned within the space, while dark curtains frame large windows.
Home in Los Frailes
4.89 out of 5 average rating, 263 reviews

casa bella 3 camas 1 king +2 twin airport 15min.

Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

Guest favourite
A welcoming living area features a comfortable wooden sofa adorned with green cushions, accompanied by two wooden chairs. A round wooden coffee table is centered on a patterned blue and white rug, while a potted plant adds a touch of greenery near a window.
Home in Ciudad Colonial
4.85 out of 5 average rating, 139 reviews

New - 3 Bd House Zona Colonial + Private Rooftop

🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Guest favourite
Home in Ciudad Colonial
4.95 out of 5 average rating, 42 reviews

Casa del Orfebre, circa 1525

Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.

Top guest favourite
A bright and airy entrance leads to a serene outdoor area with a pool. The space is framed by modern glass walls, showcasing inviting seating and greenery. Natural light filters through, enhancing the layout that connects indoor and outdoor living.
Home in Ciudad Colonial
5 out of 5 average rating, 56 reviews

Stunning villa in Zona Colonial

Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Guest favourite
The living area features a light blue sofa paired with a small neutral-toned coffee table. A colorful piece of wall art hangs above the sofa, and a dining table is visible in the corner. A ceiling fan and green curtains enhance the space, while natural light enters from a nearby window.
Home in Santo Domingo
4.95 out of 5 average rating, 167 reviews

Cozy, central and well-equipped place

We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Guest favourite
Home in Ciudad Colonial
5 out of 5 average rating, 6 reviews

Casa Aurelia + Pool + Sleeps 4

Set in the heart of the Zona Colonial, this beautifully restored 17th-century home blends authentic colonial architecture with a fresh, modern feel. Domus Santa Bárbara features five thoughtfully designed apartments surrounding a stunning pool, reserved exclusively for our guests. Enjoy an unforgettable stay in a space where heritage meets modern living—ideal for relaxing, unwinding, and creating memorable moments together.

Superhost
A welcoming sitting area features a comfortable gray sofa paired with two wicker chairs and a glass coffee table. Lush green plants are placed around the space, enhancing the ambiance. Colorful tiles cover the floor, contributing to a cozy atmosphere.
Home in Ciudad Colonial
4.93 out of 5 average rating, 230 reviews

Cozy little house in the heart of the Colonial Zone

A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Top guest favourite
A covered terrace features a wooden floor, surrounded by potted plants. Four chairs with colorful cushions face a wooden table. A hammock and a cozy blue chair are positioned nearby, with an open view of the rooftops in the background.
Home in Ciudad Colonial
4.96 out of 5 average rating, 115 reviews

Charming Old City Corner House

This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Superhost
An infinity pool extends towards the horizon, creating a seamless view of the ocean. Palm trees frame the area, providing a tropical ambiance. The clear water reflects the blue sky, enhancing the tranquil setting.
Home in Santo Domingo
4.86 out of 5 average rating, 7 reviews

House in the city with an oceanfront swimming pool

Oceanfront house in a private residential development. Unique location because it is in the city (west). Main room on the second floor, open to the sea. Kitchen in the main room. 4 bedrooms with one facing the sea and 3 full bathrooms in total in the house and one downstairs for visitors. Gym. Billiard room. Pool and Jacuzzi. Large private garage with electric door.

Popular amenities for house rentals in Santo Domingo

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