
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Quick stats about house rentals in Santo Domingo

Total holiday rentals
Explore 490 holiday rentals in Santo Domingo

Nightly prices starting at
Santo Domingo holiday rentals start at £7 per night before taxes and fees

Verified guest reviews
Over 13,190 verified reviews to help you choose

Family-friendly holiday rentals
190 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 120 rentals that welcome pets

Holiday rentals with a pool
100 properties feature pools

Rentals with dedicated workspaces
180 properties have a dedicated workspace

Wifi availability
460 of Santo Domingo holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Santo Domingo rentals

4.7 Average rating
Santo Domingo stays receive an average rating of 4.7 out of 5 from guests
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

casa bella 3 camas 1 king +2 twin airport 15min.
Relájate en este espacio tranquilo,elegante y seguro aeropuerto (15 minutos) playas ,calles principales Supermercados cerca (zona súper tranquila segura y muy confortable ) 1–incluimos servicio de lavado y secado 2–wifi 3–Tv Smart 55 sala y 65 hab principal 4–puerta principal inteligente con clave 5–muebles en leather 6– cama principal king size 7–aire acondicionado en la principal 8–parqueo techado y cerrado 9–inversor de Luz 24 horas incluido Soy súper atento con mis huéspedes

New - 3 Bd House Zona Colonial + Private Rooftop
🌴🥥 Welcome to the perfect oasis in the Dominican Republic. We are so happy to host you ! We are centrally located in La Zona Colonial, the historic central neighborhood of the Dominican Republic's capital, Santo Domingo. It is the oldest continuously inhabited European-established settlement in the Americas. We are steps away from restaurants, night life, bars, museums and landmarks. Casa Altagracia is an eclectic, unique and curated house welcoming families, couples and friends.

Modern apartment in the Ciudad Colonial area
Exclusive apartment in the Colonial City of Santo Domingo, ideal for those seeking history, comfort and a unique experience. Located in one of the city's most iconic areas, this elegant property combines colonial charm with modern amenities. It has one bedroom, a spacious and bright living room, and a fully equipped kitchen. Its main attraction is a spectacular private terrace with a hot tub (room-temperature water), perfect for relaxing and enjoying the Caribbean climate.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Casa Aurelia + Pool + Sleeps 4
Set in the heart of the Zona Colonial, this beautifully restored 17th-century home blends authentic colonial architecture with a fresh, modern feel. Domus Santa Bárbara features five thoughtfully designed apartments surrounding a stunning pool, reserved exclusively for our guests. Enjoy an unforgettable stay in a space where heritage meets modern living—ideal for relaxing, unwinding, and creating memorable moments together.

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.

House in the city with an oceanfront swimming pool
Oceanfront house in a private residential development. Unique location because it is in the city (west). Main room on the second floor, open to the sea. Kitchen in the main room. 4 bedrooms with one facing the sea and 3 full bathrooms in total in the house and one downstairs for visitors. Gym. Billiard room. Pool and Jacuzzi. Large private garage with electric door.

Heart of the colonial zone, Billini 54
At the very heart of the most exclusive part of the colonial city where all the fun and interesting activities take place. This beautiful one-bedroom apartment is on the first floor of a small building next to the colonial gate 4D cinema, electric bike rentals, beer market, food markets, historical landmarks, exclusive boutiques, galleries, restaurants and bars.
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

Cheerful 4 bedroom home with pool and parking

House for groups with a pool SDE

PrivatePool - BBQ - Terrace - Excelent for Big Fam

Colonial Oasis

White House Villa Santo Domingo

Private Home, Hot Water, Security, Pool and Patio

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Casa Escondidas is close to everything you need.
Weekly house rentals

Elegant Luxury Home+ Rooftop Jacuzzi Zona Colonial

Zona Colonial large 2br AC hot water Wi-Fi w/patio

Luxury, Classy Private House In Santo Domingo

Luxury house in the East Zone

Beautiful View Home

Casa Grullon - Loft. Comfort & ancient beauty meet

Beautiful modern Colonial House with terrace

Cozy house in Santo Domingo
Private house rentals

villa yaya

Near Zona Colonial. Quiet charming home in Gazcue

"Villa M & M Dream Getaway and Total Relaxation"

Private pool and unique murals in a tropical oasis

Charming 2BDR Suite! - SPECIAL PROMOTION

Comfortable house 2 floors, 3 minutes from Los Tres Ojos

Villa Marayath!To enjoy with all families & friend

Amazing house with pool in Santo Domingo
When is the best time to visit Santo Domingo?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £37 | £37 | £37 | £37 | £37 | £37 | £37 | £37 | £37 | £37 | £37 | £37 |
| Avg. temp | 26°C | 26°C | 26°C | 27°C | 27°C | 28°C | 28°C | 28°C | 28°C | 28°C | 27°C | 26°C |
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- Pet-friendly rentals Santo Domingo
- Rentals with an EV charger Santo Domingo
- Rentals with a cinema Santo Domingo
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- Family-friendly rentals Santo Domingo
- Loft rentals Santo Domingo
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- Hostel rentals Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- Holiday home rentals Santo Domingo
- Guest house rentals Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Rentals with pools Santo Domingo
- Rentals with a washing machine and dryer Santo Domingo
- Rentals with outdoor seating Santo Domingo
- Boutique hotels Santo Domingo
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- Rentals with a patio Santo Domingo
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- Hotel rooms Santo Domingo
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- Villa rentals Santo Domingo
- Rentals with an accessible-height bed Santo Domingo
- House rentals Distrito Nacional
- House rentals Dominican Republic
- Playa Nueva Romana
- Ciudad Juan Bosch
- Malecón
- Metro Country Club
- Playa Guayacanes
- Blue Mall
- Downtown Center
- Playa Hemingway
- Megacentro
- Teatro Nacional Eduardo Brito
- Agora Mall
- Zona Colonial
- Galería 360
- Bella Vista Mall
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Parque Iberoamerica
- Cathedral of Santa María la Menor
- Juan Dolio
- Columbus Park
- Playa Caribe
- The 3 Eyes National Park
- Casa De Teatro
- Columbus Lighthouse
- Museum of the Royal Houses
- Things to do Santo Domingo
- Tours Santo Domingo
- Nature and outdoors Santo Domingo
- Food and drink Santo Domingo
- Things to do Distrito Nacional
- Nature and outdoors Distrito Nacional
- Food and drink Distrito Nacional
- Things to do Dominican Republic
- Tours Dominican Republic
- Sightseeing Dominican Republic
- Food and drink Dominican Republic
- Nature and outdoors Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Art and culture Dominican Republic







