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Boutique hotels in Southern United States

Find and book unique boutique hotels on Airbnb

Top-rated boutique hotels in Southern United States

Guests agree: these boutique hotels are highly rated for location, cleanliness and more.

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Top guest favourite
Hotel room in Galveston
4.94 out of 5 average rating, 484 reviews

The Louis Suite | Walk Downtown

One of six rooms at Saint Helens House-Hotel. See all our rooms: www.airbnb.com/p/sthelenshouse Light-filled corner suite at the top of the grand staircase with vintage charm and subtle Art Deco touches. • Private en suite bathroom • Penny tile & brass fixtures • Vanity with makeup lighting • Carved French Louis XIV bed • Four tall windows • Blackout shades • Walk to UTMB, downtown & cruise terminals * Note: Private in-room bathroom added in 2025, older reviews may mention a shared bathroom.

Guest favourite
A spacious room features large windows overlooking Beaver Lake, allowing natural light to fill the space. A cozy sitting area includes a beige sofa and a rustic coffee table, while a queen pillow-top bed is positioned nearby. Accent walls of natural stone add texture to the room.
Hotel room in Eureka Springs
4.95 out of 5 average rating, 284 reviews

Romantic Lakeview Jacuzzi Suite

Jacuzzi Suites are the size of a hotel room with the privacy of a woodsy cabin. Our suites the perfect way to spend a romantic getaway. Each suite has a queen pillow-top bed, a sitting area, a Jacuzzi for two and a small deck with a stunning view of Beaver Lake. No kitchens; however, each one has a coffee bar w/ mini fridge, microwave and Keurig. Each suite has its own private boardwalk entrance to ensure privacy. We have 3 suites attached to the office building. No pets allowed in the suites.

Top guest favourite
A grand, two-story house is set against a blue sky, featuring a spacious front porch with rocking chairs. Lush green landscaping surrounds the property, while a circular flower bed enhances the welcoming entryway.
Hotel room in Cape Charles
4.98 out of 5 average rating, 289 reviews

The Laughing King Retreat, Honeymoon Island Suite

The Laughing King Retreat is an adults only, organic waterfront farm situated directly on the peaceful waters of the Chesapeake Bay. Your private guest suite will enjoy breathtaking sunrises and sunsets, private waterfront pool, private beach, hiking trails, miles of soft sugar sand sandbars to explore and enjoy. Private Chesapeake Bay water access for boating, swimming, paddle boarding, fishing or just soaking. For a complete list of all the retreat rooms click the photo of me and Suzanne.

Top guest favourite
A spacious room features antique stone walls and hardwood flooring. A large wooden bed is flanked by two lamps, with decorative pillows adding color. A seated area includes a soft chair, and a dresser complements the warm, inviting decor.
Hotel room in Eureka Springs
4.99 out of 5 average rating, 325 reviews

Downtown luxury suite, privacy and convenience!

Relax in a spacious, private suite that allows you to stretch. The Anderson Suite at Twilight Terrace offers 800 gorgeous square feet. Feel right at home with the great Arts and Crafts décor, a kitchenette with fridge and microwave, Wifi and a flat screen TV with cable. The bath boasts a jet tub for 2 and a tiled shower for 2. Antique accents with modern amenities give you a comfortable, luxurious base to enjoy Eureka Springs! Add in OFF-STREET PARKING and you’re set for a fabulous stay!

Guest favourite
The Grand Manor is showcased in an aerial view, framed by tall palm trees and a vibrant sunset sky. The elegant architecture features a three-story structure with a wrap-around porch, beautifully lit pathways, and lush greenery in the front yard.
Hotel room in Galveston
4.88 out of 5 average rating, 750 reviews

Tropicana Suite-Grand Manor Luxury Mansion Loft

The elegant Grand Manor (3.5 blks to cruise) Built 1905, a true southern tropical mansion. Luxury amenities seamlessly blended with Victorian grace (6 other rooms avail) Located in Galveston's East End Historic District , considered one of the top architectural structures on the Island Guest rooms are richly appointed, with king size beds. Private baths are soaker or claw-footed tubs. Best walking location to Island Funky bars & rooftop patios,harbor minutes to WORLD FAMOUS STRAND

Superhost
A rooftop terrace offers unobstructed ocean views, featuring two unique hanging chairs and a selection of lounge chairs. Lush palm trees provide a tropical feel, and the wood deck contrasts with the vibrant blue sky and ocean. The area is designed for relaxation and enjoyment.
Hotel room in Central Beach
4.8 out of 5 average rating, 1640 reviews

King Room - Oceanfront Property

The king room is our smaller economical option at 220 sq. ft. It's made for travelers to save money and doesn't face the ocean. We also have 450 sq. ft. studios & oceanfront suites for just a bit more. We're a small historic boutique hotel in Fort Lauderdale Beach, 60 ft from the ocean. We have a rooftop terrace and 2nd fl terrace. We have free beach gear, free WiFi, and $10+tx/day parking for a small or midsize car. The main guest MUST be 25+ so families don't have to worry about parties.

Top guest favourite
The room features exposed brick walls and a wooden ceiling, enhancing the rustic charm. A spacious bed sits beside a cozy seating area with an orange armchair and a guitar. Natural light floods in through multiple large windows, with decorative elements like a cowhide rug and artwork adding character.
Hotel room in Hannibal
4.97 out of 5 average rating, 164 reviews

The Woodsman Suite

A third floor suite, facing the river with the train tracks only a couple blocks away. It took 2 months to do the ceiling. Carefully polished and placed the old lath in a specific design, the ceiling is a work of art. Eighty percent of the material used in this room is from re purposed lumber, either from this building or from a childhood barn built in the late 1800's. It will take you a while to notice every detail down to the toilet paper holder which is from an old barn post.

Top guest favourite
An outdoor seating area is located on the rooftop with bright yellow chairs and wooden tables. The backdrop features a panoramic view of the Austin skyline, showcasing modern buildings and clear blue skies.
Hotel room in Downtown Austin
4.95 out of 5 average rating, 338 reviews

New High Rise 2 Bedroom Condo Rainey District

Luxury high rise condo in the heart of the Rainey Street! The best location for living, entertaining, and experiencing SXSW! Centrally located to everything downtown Austin has to offer, Austin City Limits, Rainey street bars and restaurants, 6th Street, live music, museums, Lady Bird Lake all within minutes! The roof top pool, cabanas, and entertaining spaces on the 33rd floor are literally breathtaking with amazing views of the Austin downtown skyline and Lady Bird Lake

A round wooden dining table is surrounded by six matching chairs in a sunlit room. Large windows reveal a scenic view of the beach and gulf beyond, with natural light flooding the space. A ceiling fan provides a cooling breeze, enhancing comfort.
Hotel room in Grand Isle
4.81 out of 5 average rating, 53 reviews

Gulf Front Suite - 2 Bedrooms with Kitchen

Wake up at our Gulf Front Suite with a view of Louisiana's gulf coast. This two bedroom suite is located at the Inn, directly on the beach. The Gulf Front Suite has one of two options: (a) #5 has a double bed in each bedroom and a single bed and a futon in the living room; (b) #6 has a double and a single in each bedroom and a futon in the living area or (c) #7a. Our full-size kitchen includes a refrigerator, sink, electric stove, microwave, coffee maker, and dishes.

Guest favourite
A comfortable bed is adorned with decorative pillows in soft yellow and a floral design. A framed art piece and an elegant lamp are visible on the bedside table, contributing to the cozy ambiance. Natural light filters through the window, complemented by soft drapes.
Hotel room in Denton
4.95 out of 5 average rating, 133 reviews

The Magnolia Room at The Brownlow House.

Walking distance to the Denton square! Our boutique hotel has been artfully designed with understated elegance & luxury. The Magnolia Room is a large room with ample sitting space. It receives lovely morning light, as it overlooks the front yard and Locust St. The bathroom has a private toilet room for the toilet/sink, and a charming claw foot tub (located in the main room). All our rooms have queen beds and a 42” smart TV for your use during your stay.

Superhost
A rustic cabin exterior features a sturdy wooden door framed by stone and log accents. A small charcoal grill is positioned nearby on a concrete slab, while a natural stone pathway leads to the entrance. Surrounding greenery adds to the cabin's secluded feel.
Hotel room in Davis
4.8 out of 5 average rating, 97 reviews

Cabin Villa 5 -Riverview inside Turner Falls Cabin

Beautiful views inside Turner Falls Park. Things to Do in Turner Falls Park! Natural Pool in Turner Falls Park Turner Falls Park is one of the best places for you to spend your vacation. There are a lot of things in this park that attracts a lot of people for far away cities. One of the thing that is most attractive is the biggest waterfall in Oklahoma. People love to come and see this beautiful waterfall and have a little swim in its natural pool.

Top guest favourite
A charming living area features a vibrant blue fireplace surrounded by decorative accents. A wooden coffee table rests on a cowhide rug, complemented by a brown leather couch. Colorful wall art and mirrors enhance the space, while a front door with stained glass adds character.
Hotel room in Eureka Springs
4.96 out of 5 average rating, 295 reviews

Clean, Eclectic, Private stay in Historic Loop

We offer a uniquely Eurekan experience on the upper loop of the Historic District. We are within walking distance to shopping, dining, and entertainment and right next to the trolly stop for those who prefer to ride! Enjoy two bath options with our oversized Jacuzzi tub or old-school claw-foot tub/shower! You will have a designated parking spot off the street and a private patio to people watch as you sip coffee, tea or a nightcap of your choice.

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