
Family-friendly holiday rentals in Downtown San Diego
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Downtown San Diego
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

Vintage Spanish Revival Home - Balboa Park - Alcazar Court
• 1924 Spanish Revival Bungalows - Alcazar Court - Nestled in the heart of the city in historic Hillcrest - with cafes, bars, and shops • Fully equipped 1 bd 1 ba bungalows complement shady olive tree-lined patios - guests can enjoy coffee in the morning - a glass of wine in the afternoon. Enjoy the charm and tranquility of a bygone era and convenience of modern amenities, • Explore nearby Balboa Park, home to 16 museums and performing arts venues, as well as the world-famous San Diego Zoo.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

Trendy Studio, Natural Light - Heart of Downtown
Large studio with comfortable queen sized Murphy Bed, a love seat, private entrance and private bath. Located in Cortez Hill - walk to the nicest neighborhoods in downtown like Little Italy, Gaslamp, East Village, and the Embarcadero. There is no full kitchen, but there is a small refrigerator, small microwave, and a pot for heating water. This is an ideal space for solo travelers, couples, events at the Convention Center, Padres Games, great eateries, and the best of Downtown San Diego.

Modern Inner City Pad w/ Patio | Walk Everywhere!
Enjoy everything Little Italy has to offer right on your doorstep from this bright, light and inviting apt. Open the floor-to-ceiling glass doors and let the sounds of the city in as you relax on the lounge and shaded patio. Cook in the modern kitchen, feel pampered in the luxe bathroom, then retire to the chic, king bedroom. Explore quaint streets, cafes, gelato shops, and charming trattorias just steps away then discover downtown, Balboa Park, & the Gaslamp Qtr, an easy 5/10 min drive away!

BEST LOCATION in all of Little Italy & downtown!
Location, location, location! Can't get any closer to the bustling Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. One of the only houses in all of downtown! This modern luxury home is just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & San Diego Zoo! All the frills: ++ Prime location! 98/100 Walker Score rating ++ High-speed internet, Netflix & smart TV ++ A/C ++ Super Host 5-star service

Calm Luxury Penthouse Getaway With Panoramic Views
Welcome to the most relaxing and luxurious penthouse condo in Little Italy! Featuring 2 expansive balconies with sweeping views, my condo sleeps 4-6 comfortably and is situated right in the heart of San Diego's most desirable neighborhood, Little Italy. Enjoy an area that is rich in exquisite cuisine, boutiques, patio cafés, exciting bars and local breweries. Area amenities nearby feature the famous San Diego Zoo, beautiful Balboa Park, Waterfront Park, the Convention Center and much more!

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV
Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Kettner Row | Staycation-Featured Icon
Welcome to Kettner Row, a rare architectural masterpiece featured on Staycation Sports, an Emmy-winning show on the Destination Channel! Located in the heart of Little Italy—one of San Diego’s most desirable neighborhoods—and designed by renowned architect Jonathan Segal, FAIA. This detached row home is situated in the award-winning Little Italy Neighborhood Developers block (LIND). This modern home features dual master suites, a high-end designer kitchen, and luxurious spa bathrooms.

Modern Private Loft • Walk to Petco
Stay steps from Petco Park in a thoughtfully designed two-story loft in the heart of downtown San Diego. Designed by award-winning architect Jonathan Segal, this modern space features high ceilings, a calm open layout, and a private balcony with city views. Enjoy a queen bed upstairs and a sofa bed in the living room, plus a full kitchen, washer/dryer, and easy self check-in. A more spacious, private, and relaxed alternative to typical downtown hotel stays.

Stylish Downtown Loft | Free Parking Near Bay
Tucked into the heart of Little Italy, this sun-drenched architectural loft is a calm, beautiful place to land in the middle of everything. Exposed brick, tall ceilings, and a chic open layout create a warm, inspiring retreat. Walk to top restaurants, cafes, bars, and Waterfront Park. Includes a cozy raised bed with ladder access, a full kitchen, one free onsite parking spot, and optional dog stay with $50 fee.

At Mine | Spacious Suite in the Gaslamp Quarter
This meticulously renovated historical hotel suite, designed by Pininfarina, is located in Downtown San Diego’s vibrant Gaslamp Quarter, surrounded by restaurants and nightlife. It offers private, spacious accommodations for both business and leisure travelers, featuring a king bed, smart TV, central AC, and mini-fridge. Please note: an adjoining bar operates until midnight, and some noise is expected.

King Size Luxury Loft Petco-Park-Downtown SD
This gorgeous loft is situated in the heart of Downtown San Diego. Adjacent to East Village-Petco Park. This ground-level unit offers easy access and central location within walking distance to restaurants, bars, cafes, and the convention center. Because the property is located in a lively downtown area at street level, guests may occasionally experience typical city Noice or activity
Popular amenities for Downtown San Diego family-friendly rentals
Family-friendly home rentals with a hot tub

Hidden Spa w/ Sauna and Hot Tub near Balboa Park

Cozy University Heights Cottage

Luxe Home w. Serene Backyard Spa

Beautiful Historic Home and Gardens Near Downtown!

Mountain View• Solar-heated Pool •HotTub •GameRoom

5 Bed Oasis | Ocean View, Hot Tub, BBQ, Parking

Midcentury Lux 4BR home w Pool/Spa/Cabana/Firepit

Dream Penthouse! The Most Amazing Bath & Views
Family- and pet-friendly home rentals

Historic Golden Hill Post Office - 3 BR w fire pit

Little Italy 2BR Loft Near Waterfront & Convention

Luxury Family Home Near Dining, Shops + Zoo

Stylish/Modern/Gaslamp/Spacious 1BR/1BA

Downtown/GasLamp/ Best Location

Modern House In The Hills | Killer Location!

Sunlit Studio Hideaway | Walk to Gaslamp & More

Sauna, Ice Bath, Jacuzzi & Firepit, Rest & Relax
Family-friendly home rentals with a pool

Beach<15min,Heated Pool,New Central AC, 4Br Family

La Jolla Beach House-Family Focused-3min to Beach

Casa Bahia Beautiful San Diego Home with Pool

Bright and spacious home with views, pool & spa.

Designer Luxury Rental With Pool

ModernCoastal I View I Pool ITub

Upscale Resort House /Views, Saltwater Pool/Spa !

Oasis with ocean views/Pool/Hot tub! Sleeps 10!
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £149 | £152 | £165 | £150 | £166 | £170 | £196 | £169 | £152 | £157 | £161 | £166 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about holiday rentals that are family-friendly in Downtown San Diego

Total holiday rentals
Explore 770 holiday rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego holiday rentals start at £30 per night before taxes and fees

Verified guest reviews
Over 31,460 verified reviews to help you choose

Pet-friendly holiday rentals
Find 260 rentals that welcome pets

Holiday rentals with a pool
210 properties feature pools

Rentals with dedicated workspaces
490 properties have a dedicated workspace

Wifi availability
770 of Downtown San Diego holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests – averaging 4.8 out of 5!
Destinations to explore
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- House rentals Downtown San Diego
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- Waterfront rentals Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with a patio Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Rentals with a firepit Downtown San Diego
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- Serviced apartment rentals Downtown San Diego
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- Family-friendly rentals San Diego
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- Family-friendly rentals United States
- Rosarito Beach
- San Diego Convention Center E Ent
- SeaWorld San Diego
- Petco Park
- University of California-San Diego
- Oceanside City Beach
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- Coronado Beach
- Torrey Pines State Beach
- San Diego Zoo
- Tijuana Beach
- Balboa Park
- San Diego State University
- Mission Beach
- LEGOLAND California
- La Misión Beach
- Moonlight State Beach
- Liberty Station
- Oceanside Harbor
- Sesame Place San Diego
- Belmont Park
- Black's Beach





