
Hotel holiday rentals in Downtown
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Top-rated hotel rentals in Downtown
Guests agree: these hotel rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for hotel rentals in Downtown
Family-friendly hotel rentals

Stylish San Diego downtown Suite

Relax and Recharge! Pool, Beach Access, Parking!

Ocean Beach - Bed in a 8-Bed Mixed Dorm

Ocean Beach - Bed in 6-Bed Female Dorm

Studio 2 Queen Beds at Hard Rock Hotel San Diego!

Budget-Friendly Stay w/ Easy Access to SeaWorld

Stay Near Top Attractions | Balcony & Pet-Friendly

Ocean Beach - Bed in 6-Bed Mixed Room
Hotel rentals with a pool

Recently reno’d escape near the Gaslamp Quarter

Iconic Resort in San Diego

2 Pet-friendly Rooms—Minutes to Mission Bay Beach

Playful escape near games & concerts at Petco Park

Studio San Diego Marriott

Family Getaway w/ Pool & Free Airport Shuttle

Downtown Delight: Pets Allowed, Parking, Pool!

Comic-Con 2026 in San Diego @ Marriott Pulse Suite
Hotel rentals with a patio

Modern King Room | Luxe Stay in Little Italy

Club Wyndham Harbour Lights

Comic-Con 2026: Spacious King Suite + Sofa Bed

ITH Mission Beach Backpacker Hostel Mixed Dorm

2 bd/2 bth Resort Style Hotel

Nice Property, stay right in SD!

Worldmark Studio Sleeps 4

WorldMark San Diego Mission Valley Two Bedroom
Quick stats about hotel rentals in Downtown
Total rentals
260 properties
Nightly prices starting at
£30 before taxes and fees
Total number of reviews
4.2K reviews
Family-friendly rentals
60 properties are a good fit for families
Pet-friendly rentals
90 properties allow pets
Rentals with a pool
160 properties have a pool
Destinations to explore
- Rentals with outdoor seating Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Flat rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- House rentals Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Waterfront rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Hostel rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Apartment rentals Downtown San Diego
- Rentals with a cinema Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with a beach view Downtown San Diego
- Rentals with a washing machine and dryer Downtown San Diego
- Rentals with a patio Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with a firepit Downtown San Diego
- Hotel rentals San Diego
- Hotel rentals San Diego County
- Hotel rentals California
- Hotel rentals United States
- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Pacific Beach
- Tijuana Beach
- SeaWorld San Diego
- University of California San Diego
- LEGOLAND California
- Coronado Beach
- San Diego Zoo Safari Park
- Balboa Park
- La Misión Beach
- Oceanside Harbor
- Coronado Shores Beach
- Black's Beach
- Belmont Park
- Moonlight Beach
- Liberty Station
- Sesame Place San Diego
- Law Street Beach
- Torrey Pines Golf Course
- Santa Monica Beach
- Mission Beach
- USS Midway Museum