
House holiday rentals in Downtown San Diego
Find and book unique houses on Airbnb
Top-rated house rentals in Downtown San Diego
Guests agree: these houses are highly rated for location, cleanliness and more.

Walk to Balboa Park and Hillcrest from an Immaculate Home
Take a stroll through the park, then unwind with a leisurely dinner under the festoon lights. Classic crown molding, hardwood floors, and pared-back tones of gray and taupe create an air of calm at this elegant haven spread out over 1500 square feet. You will find the space charming & spacious with over 1500 sq. feet. This single level property is the lower level of a historic duplex. Hardwood floors, crown molding, gas fireplace and laundry room. Street parking is usually readily available. This A+ location of Banker's Hill is NOT impacted by air plane noise. Enjoy the entire lower level duplex and use of the back yard with patio set for dining. Please note the upper tenant may also want to use this space so this area could be shared. We would love to greet you but are also fine with allowing you to access with a code on the front door. We live nearby and are happy to make suggestions for dining or things to do. Located near numerous restaurants, and Balboa Park, Hillcrest, the zoo, Downtown, Little Italy, and the Convention Center are all within 10 minutes. Be at the beach in less than 15 minutes. The bus line runs up First Ave for easy access to Downtown and Uptown. Near trolley and train station. We are within 10 minutes to the San Diego International Airport and a quick Uber ride to Downtown, Little Italy. Walk to the heart of Hillcrest, Balboa Park and the Zoo. Be at the beach in less then 15 minutes. Central location near the I-5, I-163 & I-8. Because of the hardwood floors, you will hear the footsteps above. The kitchen is well stocked if your a cook and we have an area where you can set up your laptop. wireless available and 3 smart TV's for your enjoyment. Small market less than 1 block away.

Admire Harbor Views from the Porch at a City Gem
Unwind in a cozy colorful casita in this light-filled 1920s Spanish bungalow decorated with Mexican folklorico. Take a walk into Little Italy for dinner. Or to a show at the Old Globe.What’s best, is how close you are to so much, all without needing a car. A very small single car garage is provided, think compact car. Street parking is free but challenging at times. The house is located directly below the incoming flight path. You are encouraged to read the reviews regarding this.Ideal for four.

NEW Luxury 3BR HOUSE❤️of DT Walk Petco w/Garage AC
Located in the heart of Downtown San Diego, this unique house has been completely remodeled and re-imagined to make your stay unforgettable. Designed with the eye toward comfort and entertainment. 7 min walk Petco Park/14 min walk to Convention Center/6 min to Zoo/9 min Airport/12 min to SeaWorld/9 min to Coronado *Stunning bathrooms w/ dual showers, tub, smart glass *Full Kitchen, AC Central *SONOS Sound System, 4K TVs every room *Walk to coffee, yoga & gyms, dining, entertainment, shopping!

EpicViews | 3-Stories with Rooftop | Cortez Hill
📍 Unbeatable Central Location! Welcome to Casa Cortez Hill! This charming 3-story home features 3 bedrooms, 2 baths, and a private 4th-story rooftop deck with firepit. At 1,510 sq ft, it comfortably sleeps up to 8 guests. Centrally located—walk to Little Italy, Gaslamp, and Petco Park. Just few miles from the airport and minutes to the beach. Enjoy San Diego’s best dining, nightlife, and coastal vibes. Casa Cortez Hill is your home base for all things San Diego. We can't wait to host you!

#1 LOCATION - Rare Luxury Home in Downtown
***THE BEST RATED RENTAL IN DOWNTOWN SAN DIEGO*** Location doesn't get better than this! Right in the heart of the lively Little Italy area in downtown San Diego. San Diego's best restaurants and nightlife in your backyard. Just blocks from the waterfront and a short Uber or walk to the Gaslamp, Convention Center & Zoo! All the frills: + Prime location! 98/100 Walker Score rating + Private parking + Private Sundeck & Backyard Stay at this modern luxury home for your next trip!

Little Italy 2BR Loft Near Waterfront & Convention
Discover the heart of San Diego from our spacious loft in Little Italy, the culinary gem of downtown. Perfectly situated for both business and leisure travelers, you're steps away from the waterfront, convention center, and vibrant city life. Embrace the urban experience with convenience at your doorstep, including eclectic bars and restaurants. We provide a white noise machine and earplugs, though the lower floor offers a quieter retreat. Experience the best of city living!

The Island View Penthouse
⸻ Welcome to our sophisticated three-bedroom, three-bath retreat in historic Bankers Hill. Enjoy sweeping views, a full modern kitchen, and spacious living areas perfect for relaxing or entertaining. Located just minutes from Balboa Park, downtown, and San Diego’s best dining, this home blends comfort, convenience, and classic neighborhood charm. All rooms feature luxury beds from Davenport Collection. We require minimum 2-night minimum per City code, and a $299 cleaning fee.

Downtown View - 2 Story House Next to Little Italy
Two story house with 2 living rooms; 3 blocks to Little Italy restaurants, bars, & shops. Near Balboa Park, San Diego Zoo, Gaslamp, Waterfront Park & the Harbor. Museums, restaurants, theaters & nature are all nearby. Located in historic Bankers Hill, next to Interstate 5, near the airport and city center. With 2 living rooms, my house is perfect for travelers needing separate space. One parking spot is available. Extra large vehicles will have to park on the street.

Charming 3 Bed Oasis | Fire Pit, BBQ | Downtown SD
Experience San Diego in style at this beautifully furnished and ultra-comfortable 2-bedroom townhouse, located in a tranquil downtown neighborhood. Enjoy special features such as the BBQ grill and fire pit along with modern comforts like A/C, Wi-Fi, and an array of streaming services. Step out from your serene patio to a world of attractions, with Balboa Park, USS Midway Museum, Petco Park and the San Diego Zoo all at your doorstep.

🌟BEST LOCATION🌟 4BR/2BA - WALK to Little Italy 🇮🇹
Updated craftsman style home in THE BEST location! This beautiful house is close to almost everything San Diego has to offer. Only about a mile or two away from Balboa Park, the Zoo, Old Town, The Gaslamp Quarter, The Embarcadero, Hillcrest and just minutes from the airport. WALK to Little Italy in 10 minutes! Beautiful huge backyard with plenty of room to entertain. GREAT for families, or larger groups!! Sleeps 8 comfortably!

The California
Welcome to your dream vacation home in the heart of San Diego, perched high atop the hills of Mission Hills on California St! This beautifully remodeled home has breathtaking panoramic views of downtown San Diego, the sparkling bay, the airport, Point Loma, and even South Coronado Island off the coast of Baja on clear days. Come experience the best of San Diego from the comfort of your own private abode! 🌅

Hillcrest 2 bed 2 en-suite baths garage zen garden
Start your day with a freshly brewed coffee (complimentary), on the large, breezy front porch, or the calming Zen Garden, with the sounds of the granite fountain. This remodeled two Bed/two ensuite Baths, Hillcrest property, includes a resort-like landscaped garden, gazebo, BBQ area, in a zen-like atmosphere. Hillcrest location, three car garage, and plenty of free street parking.
Popular amenities for house rentals in Downtown San Diego
House rentals with a pool

Modern Central SD Home w/ Pool & Spa Near Beach

La Jolla Beach House-Family Focused-3min to Beach

Your Modern Lux Pool Resort in the Heart of SD

Casa De Colores

Luxury Family Home Near Dining, Shops + Zoo

1 bedroom, 1 bath /Hillcrest/San Diego Zoo/Balboa

Designer Luxury Rental With Pool

Heated Pool|Jacuzzi|King Bed|City Views|Chic Decor
Weekly house rentals

5 Bed 2 Bath Victorian Carriage House | Parking

Golden Hill Tree House

Hip Home with Spectacular Views

Sunset View home 2 min walk to beach parking

6BR in Mission Hills-Little Italy Area

Brunch House 3bd/2 Amazing Baths. Private yard.

Pool Oasis in Central Hillcrest by Park/Zoo

Exquisite Luxury San Diego Living In 3BR 2BA Home
Private house rentals

Designer 2BR w FirePit Near PetcoPrk, Zoo, Downtwn

Peaceful Jungle Retreat In The Heart of San Diego

Allergy free TH, rooftop, walk to Little Italy!

Modern Home - Rooftop Hot Tub with Ocean Views!

Coastal Chic Retreat in Bankers Hill

Walk to Little Italy Sleeps 8, Backyard + Parking

Panoramic Bay Views | Private Deck Bankers Hill

Little Italy Historical
When is the best time to visit Downtown San Diego?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £139 | £152 | £157 | £152 | £167 | £178 | £207 | £179 | £162 | £159 | £158 | £175 |
| Avg. temp | 15°C | 15°C | 16°C | 17°C | 18°C | 20°C | 21°C | 22°C | 22°C | 20°C | 17°C | 14°C |
Quick stats about house rentals in Downtown San Diego

Total holiday rentals
Explore 140 holiday rentals in Downtown San Diego

Nightly prices starting at
Downtown San Diego holiday rentals start at £44 per night before taxes and fees

Verified guest reviews
Over 14,210 verified reviews to help you choose

Family-friendly holiday rentals
100 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 50 rentals that welcome pets

Rentals with dedicated workspaces
80 properties have a dedicated workspace

Wifi availability
140 of Downtown San Diego holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Downtown San Diego rentals

4.8 Average rating
Downtown San Diego stays are highly rated by guests – averaging 4.8 out of 5!
Destinations to explore
- Waterfront rentals Downtown San Diego
- Resort rentals Downtown San Diego
- Rentals with an EV charger Downtown San Diego
- Rentals with beach access Downtown San Diego
- Rentals with a firepit Downtown San Diego
- Fitness-friendly rentals Downtown San Diego
- Townhouse rentals Downtown San Diego
- Flat rentals Downtown San Diego
- Loft rentals Downtown San Diego
- Family-friendly rentals Downtown San Diego
- Rentals with a hot tub Downtown San Diego
- Pet-friendly rentals Downtown San Diego
- Rentals with a washing machine and dryer Downtown San Diego
- Hostel rentals Downtown San Diego
- Hotel rooms Downtown San Diego
- Serviced apartment rentals Downtown San Diego
- Rentals with pools Downtown San Diego
- Rentals with a sauna Downtown San Diego
- Rentals with a cinema Downtown San Diego
- Rentals with a patio Downtown San Diego
- Smoking-friendly rentals Downtown San Diego
- Rentals with outdoor seating Downtown San Diego
- Boutique hotels Downtown San Diego
- Rentals with a fireplace Downtown San Diego
- Rentals with breakfast Downtown San Diego
- Apartment rentals Downtown San Diego
- House rentals San Diego
- House rentals San Diego County
- House rentals California
- House rentals United States
- Rosarito Beach
- LEGOLAND California
- San Diego Convention Center E Ent
- SeaWorld San Diego
- University of California-San Diego
- Oceanside City Beach
- Petco Park
- San Diego Zoo Safari Park
- Ocean Front Walk
- Pacific Beach
- Tijuana Beach
- Torrey Pines State Beach
- Balboa Park
- Coronado Beach
- San Diego Zoo
- San Diego State University
- Liberty Station
- La Misión Beach
- Moonlight State Beach
- Belmont Park
- Oceanside Harbor
- Sesame Place San Diego
- Black's Beach
- Coronado Shores Beach




