Holiday rentals in East Syracuse

Lovely 2-bedroom home in the heart of Syracuse

Enjoy a private space to call home in this centrally located residence. Close to Syracuse University, Downtown, Destiny Mall, Onondaga Lake, Syracuse Hancock International Airport, NY State Fair Grounds, Le Moyne College, etc. This home offers a comfy living room, dining room and a kitchen in the main floor. And the upper level features two bedrooms and a full bath. Free parking on premises enough for two vehicles. There’s plenty of space in this 1040 sqft house to feel relaxed during your stay.

Three bedroom home near downtown, SU, & Lemoyne

This cozy, stylish home boasts modern amenities and historic charm. Originally a two-bed/one-bath 1922 bungalow, we've added a master bedroom suite that feels like an escape to a spa. The freshly remodeled three-bedroom, two-bathroom home is perfect for an extended stay with family, and just right for a weekend away with friends. Within walking distance to coffee, restaurants, and cute shops. A quick, ten-minute drive to Downtown Syracuse, Upstate University Hospital, and Syracuse University.

Anne's Place

Our place is conveniently located in a quiet and safe neighborhood just off the interstate - 10 minutes from Syracuse University, LeMoyne College, hospitals and downtown. It is just minutes away from Starbucks, Panera's, Wegmans and numerous other restaurants and shopping facilities. It is also very close to the Erie Canal trail (1/2 mile) for walking, jogging or biking. We have chosen to go with a farmhouse theme with our decor. We live next door and you will enjoy total privacy when you stay.

Family Retreat |Fenced Yard | Near Hospitals & SU

Charming 3-Bedroom Home in E. Syracuse with Fenced Yard! Welcome to your cozy home away from home in East Syracuse! This charming and spacious property is perfect! The Space • Bedrooms: 3 generously-sized bedrooms with comfortable beds, fresh linens, and plenty of storage. • Bathrooms: 2 full stocked bathrooms stocked • Living Area: A warm, inviting living room with cozy seating and a large TV. • Kitchen: Fully equipped with dining area. • Backyard: A spacious, fully fenced backyard

Gracious 1920s Georgian close to hosp & colleges

The whole group will enjoy easy access to everything from this spacious, centrally located home. Close to SU, LeMoyne, ESF, St Joseph’s hospital, Crouse & Upstate. Enjoy the large kitchen and separate dining room, and relax in the living room. You can look forward to a great nights sleep in our 2- king beds in our master suites, or a full in the guest room. If you don’t require full use of the house, please let us know and we can adjust the cleaning fee prior to your booking.

Entire Modern Cozy 2BR Apt mins SU LeMoyne DT

Retro-inspired retreat with bold design, natural light, and a dedicated workspace—ideal for remote work or weekend stays. Conveniently located just minutes from key local destinations. Nearby Syracuse University & JMA Wireless Dome – ~2.5 miles / ~7 mins Le Moyne College – ~1.5 miles / ~5 mins Downtown -~3.4 miles / ~10 mins SUNY Upstate Medical University – ~3 miles / ~8 mins CNY Fertility Syracuse – ~3.4 miles / ~13 mins Syr Hancock Int'l Airport – ~4.2 miles / ~15 mins

Designer's One of a kind Sun Drenched Loft!

As you enter the 12 foot tall front door, you cannot prevent your long exhale and its associated sense of calm. Natural light bathes you from a wall of windows as your senses are heightened by artworks that are at once bold and varied set alongside furnishings that are elegant yet comfortable. Everything is in its right place and nothing has been forgotten. You have arrived at your new favorite home away from home. You can't forget this place where form and function are one.

Affordable private basement apartment

My place is 10 min from Syracuse University, Upstate University hospital, Crouse Irving hospital, 5 min from LeMoyne College, 8 min from downtown Syracuse and St. Joeseph's Health hospital, 16 min from Green Lakes State Park... You’ll love my place because of the quaintness, the quiet and the proximity to what Syracuse has to offer. My place is good for couples, small families, solo adventurers, people with animals, and business travelers.

Syracuse Cozy Home Near SU & Destiny USA, Wi-Fi

Syracuse cozy, private, clean, and comfortable guesthouse in the Eastwood neighborhood. Ideally located just minutes from Syracuse University, downtown Syracuse, major hospitals, and top attractions. Enjoy fast WiFi, a fully equipped kitchen, free parking, self check-in, and complete privacy—perfect for business travelers, medical stays, families, and extended stays. A peaceful and convenient home away from home in Syracuse.

Newly renovated & modern 2-bedroom apartment

Enjoy a stylish stay at this newly renovated apartment. Minutes from downtown, Syracuse University, Destiny USA, and top hospitals. This thoughtfully designed space features two bedrooms with comfy queen beds, a dedicated workspace, and a fully equipped kitchen. Perfect for business travelers, University visits, or a weekend getaway. Just 12 minutes from the airport, with easy access to dining, shopping and entertainment.

New 2 bedroom apartment in Syracuse!

Welcome to Syracuse! This is a 2 bedroom, 1 bathroom apartment combines modern decor with vibrant vibes that helps you unwind after a busy day in Syracuse city. Very close to downtown, Syracuse University is only a 3min drive away. Destiny mall, St. Joseph’s Hospital and Upstate Hospital only 5min drive away. Syracuse airport a 12min drive. Also there is parking on the property and brand new central AC and heat!

Renovated 1880’s Milk Barn

Experience a unique stay in our fully renovated, charming, and historic tiny home. Situated on 2.25 acres of tranquil land, you'll have the perfect blend of nature and convenience. Just 10 minutes from Green Lakes! A local Gem! 12 minutes to Destiny USA 10 minutes to downtown Syracuse 15 minutes to the SU Dome 17 minutes to the Lakeview Amphitheater.