Holiday rentals in La Mesa

4.99 out of 5 average rating, 157 reviews

Tiny home in La Mesa

Townhouse - Private Yard, La Mesa Village

Enjoy a stylish experience at this centrally-located studio. Walking distance to La Mesa Village, where you can enjoy restaurants, coffee shops, boutiques, & more. With all the things you need in a kitchen to whip up any meal, and a patio to enjoy the San Diego sun. Hop on the trolley to get to anywhere. Bringing more friends or family along with you? We also have another listing, Casa de Pueblo at the same property. 20 min drive to the Beach or Downtown 15 min drive to Balboa Park or Old Town

Superhost

Home in La Mesa

4.9 out of 5 average rating, 252 reviews

Hidden King Suite with Garden, Parking - 4 Guest

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

4.99 out of 5 average rating, 112 reviews

Emerald Suite Spa Experience with Sauna & Desk

Soothe your senses and unwind in your private spa retreat, featuring a restorative sauna, a huge soaking tub, and the refreshing scent of eucalyptus aromatherapy. Sink into a luxuriously comfortable king bed, surrounded by a calming ambiance. Thoughtful touches like plush robes and a chilled filtered water dispenser elevate your experience. Set in a tranquil neighborhood with easy access to San Diego’s highlights, this sanctuary offers the perfect blend of relaxation, rejuvenation, and comfort.

4.99 out of 5 average rating, 212 reviews

"NEW" SWEET AND COZY CACTUSVILLE STUDIO SAN DIEGO

Listing sleeps up to 4 guest. After third or fourth person an extra fee of $15. dollars per person, per night will be charged, comfortable, private studio in a great neighborhood in La Mesa. Freeway close to SDSU and the heart of downtown San Diego. Some local attractions are Sea Port Village, the world famous San Diego Zoo, Sea World, Balboa Park and much more. You may also want to see Downtown La Mesa, an 8 minute drive where there are restaurants, bars, antique shops and more to explore.

4.88 out of 5 average rating, 168 reviews

Stylish Boho Studio | Walk to Cafes | Outdoor Livi

The studio is located within a quiet leafy neighborhood right in the heart of La Mesa giving you a great base to explore everything San Diego has to offer. Inside you will find a bright, sun-filled space with a chic kitchen, an open plan living/dining area with a comfortable sofa bed, a stylish queen bedroom and a modern, sparkling bathroom with a built in laundry. Stay a short 15 min walk to a shopping center nearby with cafes, restaurants and stores and an easy 15 min drive into Downtown.

4.88 out of 5 average rating, 163 reviews

Cozy Unique Studio/One Bedroom Gem

Relax and renew at this unique and tranquil one bedroom/studio with queen bed. Comfortable and private, with an enclosed personal deck area. Includes a kitchen with an oven, full sink, refrigerator, microwave, coffee maker, and cookware/plates/utensils. Wall mounted TV with ROKU service. Bathroom with full tub. Complimentary coffee, snacks, and a pound of Starbucks coffee. Newly installed A/C unit. Gated off-street parking. No smoking in unit. Smoking is permitted on the patio. No pets.

4.99 out of 5 average rating, 192 reviews

Stunning Guest House 15 min. from Zoo, Downtown

Stunning guest house that's 15 minutes to San Diego Zoo + downtown San Diego. The cottage is decorated with mid-century and one-of-a kind furniture in a comfy living space overlooking a gorgeous garden. Enjoy the the garden on your private deck, watch TV while relaxing in the handcrafted Nicaraguan rocker or 1950s Danish slipper chair. The cottage also has a comfy queen-sized bed and a full kitchen that's stocked with what you'd need. Oh, and all guests arrive to a homemade loaf of bread.

4.99 out of 5 average rating, 252 reviews

Home in La Mesa

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

4.96 out of 5 average rating, 208 reviews

La Mesa Garden Suite

Welcome to our newly remodeled La Mesa Garden Suite - the perfect destination for your San Diego vacation! Nestled beneath a main residence in a lush backyard, this tranquil downstairs unit offers the perfect blend of privacy and convenience. Our Airbnb has its own private entrance, patio, and full bathroom. Send us a message if you have questions about our Airbnb availability. We try to accommodate as best we can. If you need anything during your stay don't hesitate to ask!

4.96 out of 5 average rating, 183 reviews

Mountain top view getaway loft

This loft is completely sound proof! VIEWS, VIEWS, VIEWS!! Do not miss this stunning contemporary loft, located in the highly desired Mt. Helix community. The guest house faces west, giving you phenomenal 270-degree views of the ocean, Downtown, Point Loma, Coronado islands, Coronado bridge, and more! Designed and built by an acclaimed San Diego home designer, this property was featured in Dream Homes Magazine and is well known for its incredible design and construction.

4.91 out of 5 average rating, 185 reviews

La Cabana

Perfect getaway for the wandering individual, couple, or young family. This rustic casita is surrounded by beautiful mountain and ocean views! Enjoy swimming in the pool, stargazing, lounging, or casual day trips around San Diego (All the amenities are shared with the main house) . The casita has one queen bed and a sofa bed, small kitchenette. Plenty of parking in driveway. Please read entire listing for details.