House holiday rentals in La Mesa

An outdoor seating area is equipped with sectional sofas arranged around a fire pit, featuring a grassy lawn surrounded by lush greenery. A large tree provides shade, while a spacious porch is visible in the background, contributing to the serene atmosphere.

4.93 out of 5 average rating, 129 reviews

Family Fun! Game Garage + Big Yard + Free Parking

Embodying the epitome of cool! This home has the perfect blend of a vintage feel with a modern touch. Stepping inside, you’re greeted by an atmosphere of fun & creativity. A large private serene retreat in the backyard w/abundant seating and fire pit. Huge 3-car garage bonus space with games. Located just minutes from downtown La Mesa, many dining options & conveniences. Everything you need & more! Distance to: San Diego Zoo: 18 min Sea World: 23 min SDSU: 13 min Airport: 19 min Gaslamp: 18 min

The property features a spacious backyard with a heated pool surrounded by lounge chairs. Palm trees line the perimeter, and soft lighting illuminates the outdoor area during sunset. The two-story house overlooks the pool, creating an inviting atmosphere for relaxation and gatherings.

4.95 out of 5 average rating, 219 reviews

XTRA 10% OFF until Nov: Pool, outdoor fire pits, c

Find your family's dream spot in San Diego! Our cozy house sits on a quiet hill, offering privacy and amazing sunset views. Dive into our pool year-round (heating at an additional cost), roast marshmallows by the fire, and cook up fun meals together. With 3 bedrooms and 2 bathrooms, it’s perfect for families, accommodating up to 9 guests. Plus, we're close to all the best attractions. Want a vacation you'll always remember? Send us a message to make it happen! 🌅🏠 We have 3 comfy beds that can

The interior of the studio showcases a spacious layout, featuring a king size bed adorned with yellow and white pillows. A dark gray sofa complements the decor, facing a coffee table with a plant. Large glass doors provide a view of the garden and outdoor seating.

4.9 out of 5 average rating, 277 reviews

2 Bed Hidden Oasis | Garden, Laundry, Parking

Capture the essence of San Diego in our Hidden King Suite with Garden hosted by Ethos Vacation Homes. The peaceful property features elite comfort for up to 4 guests with beautiful outdoors and garden, off-street parking, A/C and heating, FREE laundry, comfortable king and queen size beds, plenty of sheets and towels, a large HDTV, Netflix, Max, Hulu, Showtime, Disney+, Apple+, and ESPN+. This spacious San Diego vacation rental home has everything you need for your California Dreaming Vacation!

4.99 out of 5 average rating, 110 reviews

The exterior of a modern two-story home is displayed, featuring solar panels on the roof. Brightly lit outdoor spaces are landscaped with greenery, leading to a cozy seating area near a stylish outdoor fireplace.

Home in College East

Newly Built Upscale Home with 5 Bedrooms/6 Baths

Experience High End Luxury in our New 5 Bed/6 Bath Home. Located in a Prime area within a 15 minute drive to Downtown Gaslamp/Convention Center, San Diego Zoo, SeaWorld, World Class Pickleball Venues, and Beaches. This Custom Built Home boasts an array of amenities including En-Suite Bathrooms in Each Bedroom, Culinary Chef’s Kitchen, a Cozy Fireplace, and Large Outdoor Entertainment Space. This house is perfect for Families, Groups, or Professionals seeking an unforgettable stay in San Diego.

A spacious living area features a large leather sectional sofa positioned around a circular wooden coffee table. A wall-mounted TV is visible above a decorative fireplace, while natural light streams through a large window adorned with sheer curtains. A dining area is seen in the background.

4.87 out of 5 average rating, 107 reviews

Sunny & Spacious 3BR Retreat w/ Parking & A/C

Centrally located in La Mesa is this newly refurbished home ideal for business or pleasure with all of life’s little luxuries waiting for you to enjoy. The home features open concept living with a gourmet kitchen, a chic dining space, 3 beautiful bedrooms, 2 modern bathrooms and an expansive yard with an outdoor lounge. Walk 10 mins to Grossman Center with a Target, restaurants, cafes, a cinema & Walmart or drive to the heart of San Diego and all its attractions just 20 mins from your door.

5 out of 5 average rating, 100 reviews

A spacious studio features a purple sofa and a queen bed, both adorned with soft blankets and decorative pillows. Vibrant area rugs cover the wooden floor. Natural light floods the room through glass doors, leading to a private patio surrounded by greenery.

Home in San Diego

XLarge Artist's Retreat w/private patio/parking

*Forget your worries in this beautiful 700sq/ft spacious and serene space. *Come soak up in the artsy feel of this newly renovated large guest suite, ideally located in the middle of town close to SDSU. Roll out of bed and Enjoy a cup of coffee in the private patio then explore ALL of the city’s top attractions a short drive away. This beautiful space is clean, crisp and fully decorated with great style uniquely curated with original art by one of SD’s most established artists. * Enjoy*

A view into a modern living space reveals a sleek kitchen with bar seating and a spacious dining area. Natural light floods the room through large glass doors, showcasing lush greenery outside. A cozy area is completed with a colorful rug beneath and a inviting seating arrangement.

4.94 out of 5 average rating, 234 reviews

Cottage in the Garden! New! Modern!

COTTAGE IN THE GARDEN - New! Modern! Find beauty and serenity in this special guest house in one of San Diego's most desirable areas! Flowering bushes, plants, olive tree and fruit trees seen from all windows. All amenities: WiFi, Cable, serving dishes and tableware, full coffee bar, Ninja Blender, Flat screen TVs, 100% Egyptian Cotton Sheets or Boll and Branch Sheets (used by 3 Presidents), Japanese Toilette and more. 15 minutes to Downtown San Diego and 20 minutes to the beach!

A welcoming living area features a spacious beige sectional sofa adorned with patterned throw pillows. Natural light filters through a large window, complemented by soft, flowing curtains. A dark ottoman with decorative details adds a contrasting element to the cozy space.

4.98 out of 5 average rating, 117 reviews

Zen Retreat: 3-Bedroom Oasis near La Mesa Village

Relax in this charming 3-bedroom, 1-bathroom home located just 1 mile from the heart of Historic Downtown La Mesa Village. Nestled in a quiet, central neighborhood, this cozy retreat offers easy access to major freeways, top-rated restaurants, and the local trolley line making it a breeze to explore the best of San Diego. Within 10 to 15 miles, you’ll find yourself in iconic destinations like Downtown San Diego, Balboa Park, Coronado Island, scenic beaches, and beautiful mountain trails.

A colorful studio space features turquoise walls and a ceiling fan. A comfortable sofa with decorative pillows is paired with a coffee table. A bed with a floral-patterned comforter sits against a window, while a TV and white refrigerator complete the modern setup.

4.98 out of 5 average rating, 302 reviews

SDCannaBnB #2 *420 *parking *dog-friendly *hot tub

Welcome to SDCannaBnB - San Diego's premier cannabis-friendly rental! Our studio is newly remodeled with luxury ammenities. We proudly cater to the cannabis community and non-users alike. Our studio has HEPA air purifiers, is fully ventilated and receives deep cleanings between each guest. This ensures that every guest checks into a clean, fresh-smelling place that feels like home. Our studio is located in our quiet, fully fenced in backyard, close to San Diego's attractions

4.93 out of 5 average rating, 148 reviews

A comfortable living area features a large sectional sofa with decorative pillows. Natural light streams in through two windows, adorned with dark curtains. A rustic brick fireplace and a low wooden coffee table with magazines add character to the space, enhancing its welcoming ambiance.

Home in Rolando

(Relist!) Relax at a Stunning 1931 Historic Tudor!

Come & enjoy our 1931 historic tudor home! Beautifully rebuilt within the last 2 years. This house has a huge front lawn and space to roam. Enjoy the serenity this large property has to offer. Three peaceful patios to enjoy your morning coffee. The kitchen has an 48-inch 1950’s oven for the chef in the family. Bay windows, arched entryways and original light fixtures make this such a charming place to stay. Centrally located to enjoy everything San Diego & La Mesa has to offer.

5 out of 5 average rating, 108 reviews

Home in Rolando

Peaceful Casita | Firepit • Near SDSU

Welcome to our cozy home, perfect for couples visiting the area. It's also a great spot for SDSU parents visiting their kids. Conveniently close to the campus but far enough to enjoy some peace and quiet. If you enjoy this listing, click the heart icon ❤ in the top-right corner to bookmark it for easy access! Minutes from key attractions: ★ 6 min to SDSU/Viejas Arena ★ 14 min to Balboa Park ★ 17 min to Downtown SD (Gaslamp) ★ 19 min to San Diego Zoo ★ 21 min to the Airport

An open-concept living space features a modern kitchen with a large island and bar seating for four. A light-colored sofa is positioned nearby, with a stone fireplace adding warmth to the room. Natural light streams through the skylight and windows, enhancing the airy feel.

4.9 out of 5 average rating, 107 reviews

Bright Contemporary 5-Bedroom Oasis, Pool and Yard

Welcome to our 5-bedroom, 3-bathroom home, offering ample space for your entire group. With a myriad of amenities, games, and relaxation areas, you may find yourself wanting to spend your entire stay simply enjoying the comforts of this exceptional home. Whether that be opting for a pool day relaxing in San Diego's mediterranean climate, or cozying up next to the fireplace with your fav movie on. This spacious rental will ensure a memorable San Diego experience! 🌄

Popular amenities for house rentals in La Mesa

Kitchen

Wifi

Pool

Free parking on premises

Air conditioning

House rentals with a pool

Superhost

An aerial view captures the spacious outdoor area, featuring a rectangular pool surrounded by sun loungers and umbrellas. Lush greenery is visible alongside neatly arranged pathways and stone retaining walls, complementing the mountain-modern design of the home in the background.

Home in University Heights

4.89 out of 5 average rating, 162 reviews

Your Modern Lux Pool Resort in the Heart of SD

Superhost

The private pool area is surrounded by palm trees and cacti, with lounge chairs positioned for relaxation. A shaded dining area is visible in the background, complemented by the warm glow of a sunset sky. The scene creates a serene outdoor retreat.

Home in San Diego

4.85 out of 5 average rating, 100 reviews

Surf Cottage w/Pool & Firepit 10min from the beach

A spacious outdoor area features a clear blue pool surrounded by palm trees. Lounge chairs are positioned nearby, and a shaded table with chairs offers a spot for relaxation. The backyard showcases a privacy fence and ample sunlight.

4.85 out of 5 average rating, 229 reviews

La Mesa

Home in University Heights

A tranquil pool area is surrounded by lush landscaping, featuring palm trees and various plants. Two lounge chairs with an umbrella are positioned beside the pool, reflecting a serene evening sky with hues of pink and purple.

4.97 out of 5 average rating, 154 reviews

University Heights Oasis Getaway

4.97 out of 5 average rating, 102 reviews

Flamingo Sunset House: Sleeps 10: Pool + Hot Tub

A scenic hillside is displayed, featuring a variety of homes nestled among lush greenery. The landscape showcases a blend of residential architecture within a mountainous region, with expansive views of the surrounding area under a clear blue sky.

4.93 out of 5 average rating, 124 reviews

Updated TownHome, Great Location, Fantastic Views

4.99 out of 5 average rating, 171 reviews

A bright living space features a warm wooden ceiling and large windows. A comfortable orange sofa is paired with a wooden coffee table on a patterned area rug. The kitchen, visible in the background, includes modern appliances and white cabinetry, enhancing the cozy atmosphere.

Home in Hillcrest

Custom Guesthouse, Balboa Park/Zoo/Hillcrest& pool

4.91 out of 5 average rating, 206 reviews

A private pool is surrounded by natural stone and lush greenery. Palm trees provide shade, while a bamboo privacy fence enhances the secluded atmosphere. The clear blue water invites relaxation, showcasing gentle ripples under the sunlight.

Home in Chula Vista

Oasis with ocean views/Pool/Hot tub! Sleeps 10!

Weekly house rentals

5 out of 5 average rating, 18 reviews

A cozy outdoor seating area features two white Adirondack chairs positioned beside a small round table. The inviting entryway of the tiny home is visible, surrounded by lush greenery and trees, creating a peaceful and refreshing environment.

Home in Rolando

Tiny Home with a View

A softly lit wooden pathway meanders through a lush garden, framed by greenery. Warm lights illuminate the edges, creating a serene ambiance as the path leads deeper into the vibrant landscape.

5 out of 5 average rating, 99 reviews

Shadow House Mt. Helix

5 out of 5 average rating, 15 reviews

Airbnb Luxe: Designer Pool, Fitness and Office

5 out of 5 average rating, 14 reviews

Helix Haven

5 out of 5 average rating, 69 reviews

A modern kitchen features green cabinetry and a spacious island with seating. Stainless steel appliances and a window above the sink provide natural light. Open shelving displays kitchen essentials, while a door leads to the outside, enhancing accessibility.

Home in San Diego

San Diego's Finest Retreat

A modern living space is highlighted with a comfortable gray sofa adorned with vibrant cushions. A textured golden coffee table is positioned in front of the sofa, topped with a game and a decorative bowl. Natural light floods the area, drawing attention to the art on the walls.

4.97 out of 5 average rating, 32 reviews

25% off •Hot tub•BBQ•Patio•4 min SDSU•CentralSD

The front entrance of the house features a covered porch with a wooden deck. Two outdoor chairs are situated on the left side, alongside vibrant plants and flowers. The door is flanked by modern light fixtures, and a large window provides a view of the surrounding greenery.

4.95 out of 5 average rating, 83 reviews

Entire house, fenced yard, and driveway

An inviting outdoor space features a large hot tub, surrounded by lush greenery and spots for seating. A fire pit surrounded by comfortable seating is visible, complemented by dining options beneath umbrellas. The space is gently illuminated by soft lighting, creating a cozy atmosphere.

4.96 out of 5 average rating, 50 reviews

The Sand House-Cozy 3BR 2BA-HotTub+FirePit+Yard+EV

Private house rentals

The backyard area features a saltwater pool, surrounded by inviting lounge chairs and palm trees. A patio with umbrellas offers shaded seating, while the upper balcony of the house overlooks the scene. Lush greenery enhances the tranquil ambiance of the outdoor oasis.

4.92 out of 5 average rating, 59 reviews

5br Home with Pool, Hot Tub, BBQ, Putting green

The entrance features a welcoming pathway lined with shrubs, leading to an intricately designed front door beneath a porch light. Inside, a spacious game room showcases a pool table and a stylish bar area under modern lighting. The vibrant arcade room is visible, filled with various games. The backyard retreat boasts a sparkling pool surrounded by lounge chairs, with the evening sky enhancing the serene atmosphere.

5 out of 5 average rating, 31 reviews

Surreal Serenity Escape wIth Game Room, Pool & Spa

The living room is furnished with a comfortable loveseat and a coffee table, complemented by a white TV stand supporting a large smart TV. Decorative plants and slender white branches enhance the ambiance, while soft lighting is provided by a standing lamp. Framed artwork adorns the walls.

4.98 out of 5 average rating, 55 reviews

Discover La Mesa: Your Perfect Cozy Base

5 out of 5 average rating, 35 reviews

Home in Cherokee Point

Garden Retreat in North Park.

Superhost

A modern kitchen features sleek black cabinetry and stainless steel appliances. A spacious countertop provides ample prep area, while stylish open shelving displays decorative items. Soft natural light filters in through a window, highlighting a patterned rug on the floor.

4.72 out of 5 average rating, 18 reviews

Modern, Private, & Stylish Home

4.94 out of 5 average rating, 82 reviews

A grassy backyard features a shaded hammock suspended between trees and a dining set positioned on the lawn. Sunlight filters through the branches, creating playful shadows on the ground. The surrounding landscape includes tiered stone steps leading to elevated areas, enhancing the outdoor space.

Home in Spring Valley

Beautiful Mid-Century Home on Tree Lined Street!

Luxe

5 out of 5 average rating, 7 reviews

Hilltop Family Retreat | Heated Pool & Ocean Views