
House holiday rentals in La Mesa
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Top-rated house rentals in La Mesa
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in La Mesa
House rentals with a pool

3 BR Urban Oasis with Pool and Spa in Great Area

La Jolla Beach House-Family Focused-3min to Beach

Your Modern Lux Pool Resort in the Heart of SD

Lionhead - Private Boutique Home

Bright and spacious home with views, pool & spa.

University Heights Oasis Getaway

Oasis with ocean views/Pool/Hot tub! Sleeps 10!

Canyon House: Sunset View Tranquil Private Pool
Weekly house rentals

Cozy 1BR Home with Lovely Front Yard

Exquisite, Modern, Walk to Bliss

Sunny Loft | Beaches | Lakes | Trails

Cozy quiet getaway, great mattress (1-br)

Modern, Private, & Stylish Home

Cozy Getaway | SDSU | Firepit & Private Yard

Charming Cozy Studio Centrally Located

Luxury Hilltop Stay: Pool, Firepit & Views
Private house rentals

[1,888 SF] Casa De Rosas: Spacious home near SDSU

Cozy, cute home: Welcome to Hilltop Sanctuary

The Pool House

Lavish pool Villa In Mt. Helix, close to beaches

SunnySD Private Pool-SoCal Oasis

Sunnyside Resort Spa, Beach, Zoo, Arcade

Hilltop luxe retreat with breathtaking views

Tropical Oasis: spa, solar heated pool, waterslide
Quick stats about house rentals in La Mesa
Total rentals
290 properties
Total number of reviews
12K reviews
Family-friendly rentals
180 properties are a good fit for families
Pet-friendly rentals
90 properties allow pets
Rentals with a pool
70 properties have a pool
Rentals with dedicated workspaces
170 properties have a dedicated workspace
Destinations to explore
- San Diego Holiday rentals
- La Joya Holiday rentals
- Palm Springs Holiday rentals
- Anaheim Holiday rentals
- Stanton Holiday rentals
- Los Angeles Holiday rentals
- Santa Monica Holiday rentals
- San Fernando Valley Holiday rentals
- Channel Islands of California Holiday rentals
- Southern California Holiday rentals
- Las Vegas Strip Holiday rentals
- Henderson Holiday rentals
- Smoking-friendly rentals La Mesa
- Rentals with beach access La Mesa
- Rentals with an EV charger La Mesa
- Rentals with a hot tub La Mesa
- Pet-friendly rentals La Mesa
- Flat rentals La Mesa
- Rentals with a beach view La Mesa
- Rentals with a firepit La Mesa
- Rentals with outdoor seating La Mesa
- Private suite rentals La Mesa
- Rentals with a washing machine and dryer La Mesa
- Family-friendly rentals La Mesa
- Rentals with breakfast La Mesa
- Guest house rentals La Mesa
- Rentals with a fireplace La Mesa
- Family-friendly rentals La Mesa
- Rentals with pools La Mesa
- Fitness-friendly rentals La Mesa
- Rentals with a patio La Mesa
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- Rosarito Beach
- Oceanside City Beach
- Torrey Pines State Beach
- Tijuana Beach
- Pacific Beach
- Coronado Beach
- La Misión Beach
- SeaWorld San Diego
- Coronado Shores Beach
- Oceanside Harbor
- University of California San Diego
- LEGOLAND California
- Black's Beach
- San Diego Zoo Safari Park
- Balboa Park
- Belmont Park
- Pechanga Resort Casino
- Liberty Station
- Moonlight Beach
- Sesame Place San Diego
- Playas Los Buenos
- Playa Popotla
- USS Midway Museum
- Torrey Pines Golf Course