
Holiday rentals in Mesilla
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Top-rated holiday rentals in Mesilla
Guests agree: these stays are highly rated for location, cleanliness and more.

Conway Cottage 2
Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Southwest Mexican Adobe Casa Historic District
This wonderful adobe home with refrigerated air is located directly in the heart of the city the Mesquite Historic District of Las Cruces. This Mexican home combines the neighborhood classic adobe style. Directly across the street is a Mexican cafe and a coffee shop. Seven minute walk to downtown which has wonderful pubs and restaurants. This home is located directly across the street from my other two casitas that are listed in Airbnb. Dog fee $10.00 which can be left on the table.

One bedroom casita in Mesilla Park with hot tub
This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building is fully renovated with stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Josefina's Queen Suite in Mesilla Plaza.
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Cozy Casita De Mesilla (Mesilla Cottage)
Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

2 bed, yard, pet friendly in Historic Mesilla.
Welcome to Casa de Sapo Verde! Nestled just outside the center of the historic Mesilla Plaza and on the edge of the area’s farmland, this cozy casita is the best of both worlds. Stay in this authentic Adobe home with vigas, coved ceilings, and brick floors and experience all Mesilla has to offer. Restaurants, galleries, and shops are all nearby, or you can stroll the ditch banks by neighboring farms.

Cozy Casita with Patio
Cozy casita (guest house) with patio in nice quiet neighborhood close to NMSU, Convention center, Memorial Hospital, Mountain View Hospital, Old Mesilla, ,wine country, shopping, convenient to White Sands, hiking, etc. Casita has private entrance, private bath, small refrigerator, TV, coffee maker, microwave, and wifi

Casa Susana
Beautiful one bedroom apartment just minutes from historic Mesilla plaza. This modern space is on the 2nd floor of a lovely red barn located on 5 acres. View acres of pecan trees, in the fertile Mesilla Valley. Close to shopping and restaurants.
Popular amenities for Mesilla holiday rentals
Other great holiday rentals in Mesilla

Nature Retreat 12-min from Downtown (with pool)

Mexican Adobe Casita in Historic District

Mesilla 1869 Adobe 2 blocks from plaza

Southwest Escape

Sancho's Condo De Mesilla

Cozy downtown adobe home with hot tub and sauna

Quaint casita for 2

Raven's House
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £79 | £75 | £81 | £75 | £82 | £77 | £75 | £75 | £75 | £75 | £79 | £75 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Quick stats about holiday rentals in Mesilla

Total holiday rentals
Explore 70 holiday rentals in Mesilla

Nightly prices starting at
Mesilla holiday rentals start at £30 per night before taxes and fees

Verified guest reviews
Over 7,480 verified reviews to help you choose

Family-friendly holiday rentals
40 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 30 rentals that welcome pets

Holiday rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
70 of Mesilla holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests – averaging 4.9 out of 5!
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