
Family-friendly holiday rentals in Mesilla
Find and book unique family-friendly homes on Airbnb
Quick stats about holiday rentals that are family-friendly in Mesilla

Total holiday rentals
Explore 40 holiday rentals in Mesilla

Nightly prices starting at
Mesilla holiday rentals start at £52 per night before taxes and fees

Verified guest reviews
Over 2,550 verified reviews to help you choose

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Holiday rentals with a pool
20 properties feature pools

Rentals with dedicated workspaces
20 properties have a dedicated workspace

Wifi availability
40 of Mesilla holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated family-friendly rentals in Mesilla
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

Conway Casita 5-1
Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Josefina's Queen Suite in Mesilla Plaza.
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Little House with Private Patio and Hot Tub
Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Cozy Casita w/private patio near Old Mesilla
This adorable Casita is located in a semi-rural area just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Mesilla 1869 Adobe 2 blocks from plaza
I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Sombra Del Valle in Historic Mesilla.
Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Yucca Casita in Historic Mesilla
Mesilla STR Permit #0830 We have created a sustainable design, including rainwater harvesting and water saving landscaping, solar energy, energy saving and efficient construction, electric vehicle charger (which is solar powered), composting, organic gardens, firepit, and labyrinth.This is the 3rd unit (Yucca Casita) that we've completed, the 1st being our home and 2nd our other vacation rental property - Ocotillo Casita.

Casita de Colibrí | Hot Tub • Walk to Old Mesilla
Escape to Casa de Colibrí, a private Southwest-inspired casita just a short walk from the historic Old Mesilla Plaza, restaurants, cafés, shops, and local attractions. Relax in your private hot tub, unwind on the peaceful patio, and enjoy a comfortable stay with fast Wi-Fi, a cozy bed, and thoughtful amenities. Whether you’re here to explore Las Cruces or simply relax, Casa de Colibrí is the perfect home away from home.

Rustic Downtown Hideaway
This Rustic guest home has all the amenities, 1 Queen bed, couch sleeps small person or child, and walk-in shower. Inspired by the old west, this guest home has reclaimed wood and tin roof from an old barn in New Mexico. Within walking distance to cafes, restaurants, bars, and shops. Easy private access, keyless entry, and off street parking.
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hidden Las Cruces Retreats

Private Oasis Near Old Mesilla with Pool/Spa

Cielito Downtown

Tuscan Villa Outdoor Living, Jacuzzi & Gym

Home in Las Cruces Casa de Flores (Flower House) Near NMSU

Apache’s Retreat w/ HOT TUB & Pool table

Vacation Home
Family- and pet-friendly home rentals

Cul-de-sac Condo

Artistic Escape

Casa Mesilla

The Stranded Time Traveler; a timeless experience!

El Studio Steps from Historic Mesilla Plaza & Park

1 bed cute casita near NMSU, pet friendly

Raven's House

King Bed |Spacious house |Pets OK
Family-friendly home rentals with a pool

Luxury Home- Pool, Views, Early Check in

[Pool open] Nature Retreat 12-min from Downtown

Long term Furnished Executive apartment rentals

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Peaks Casita

Desert Oasis with Pool

Sunsets In Sonoma W/Heated Pool! Pet Friendly

Clara's Nest - The Gem of Hacienda de Las Cruces
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £95 | £100 | £92 | £86 | £92 | £92 | £85 | £86 | £77 | £89 | £92 | £93 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Destinations to explore
- Rentals with a fireplace Mesilla
- Rentals with outdoor seating Mesilla
- House rentals Mesilla
- Rentals with pools Mesilla
- Rentals with a washing machine and dryer Mesilla
- Rentals with a patio Mesilla
- Rentals with a firepit Mesilla
- Pet-friendly rentals Mesilla
- Family-friendly rentals Doña Ana County
- Family-friendly rentals New Mexico
- Family-friendly rentals United States
- White Sands National Park
- Sun Bowl Stadium
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- El Paso Zoo
- La Rodadora Espacio Interactivo
- El Paso Chihuahuas
- El Paso Museum of Art
- San Jacinto Plaza
- Farmers And Crafts Market of Las Cruces
- New Mexico Farm & Ranch Heritage Museum
- Sunland Park Racetrack & Casino
- Dripping Springs Natural Area
- Western Playland
- Southwest University Park
- Plaza Theatre
- Memorial Park
- Casa de Juan Gabriel
- Mesilla Plaza
- Museo de la Revolución en la Frontera
- Chamizal National Memorial





