
Family-friendly holiday rentals in Mesilla
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Top-rated family-friendly rentals in Mesilla
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

Charming 1930 home near NMSU/ Mesilla
Sunny two bedroom one bath house on a quiet tree lined street in Mesilla Park. Enjoy this peaceful retreat close to everything. Conveniently located near the Mesilla Plaza, NMSU, and the Convention Center. Refrigerated air set up on the Nest system. The house has internet access. The wood floors, sash windows and front screen porch give this house the character we fell in love with. We've tried to decorate it to feel like home, and provide all the amenities you might need while you're staying.

Desert Oasis with Pool
Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Relax in the ❤️ of Old Mesilla. Close to plaza.
Welcome to Casa de Martiana! This gorgeous casita is located just a few short blocks (about 1/4 mile) from the plaza in Old Mesilla where you will find tons of great restaurants (mostly delicious Mexican food), wineries, bars, unique shopping and fun events. There is a market in the square on Fridays and Sundays with neat jewelry, art and other local treasures. The area is rich in history and culture and has many tales of days when Billy the Kid and Pat Garrett used to wonder the village.

Ocotillo Casita in Historic Mesilla.
Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Historic Adobe Home- Libélula (Dragonfly)
Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A 5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

Airstream Airdream w hot tub!
Welcome to the “Retro Retreat,” a 1968 Land Yacht infused with NM’s enchantment. This vintage stay has been lovingly curated with elements of nostalgic Americana and contemporary desert chic, featuring vintage books, games, and iconic art. This fully restored tiny stay set amidst a pecan field in the Mesilla Park district offers modern amenities including a remodeled bathroom with shower, Wi-Fi, Smart TV, a mini-split for easy heating and cooling, and a private hot tub for relaxation.

Josefina's Queen Suite in Mesilla Plaza.
Josefina's Queen Suite is located just off the Plaza in Historic Old Mesilla. Behind the thick adobe walls, you will find this tranquil retreat. Charmed by the ambiance of our historic Southwestern design and the Garden Greenhouse, our luxurious Queen Suite offers a cozy step back in time, weaving together old world charm and modern comforts like WIFI, mini fridge, Smart TV, AC, plush bathrobes and more. If the Queen suite is already booked, please check out our King Suite!

Getaway Guesthouse in Historic Mesilla
Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Little House with Private Patio and Hot Tub
Our guesthouse is located on historic Highway 28, also known as the Don Juan de Onate Trail, which connects El Paso and Las Cruces. It is one of the area's most scenic routes. You can find breweries, multiple wineries, and the famous Chopes restaurant and bar along the route. The highlight of the 10-mile drive from our little house in San Miguel to historic Mesilla takes you through unique canopies of pecan trees, in the largest pecan-producing county in the nation.

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

Sombra Del Valle in Historic Mesilla.
Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Cozy Casita w/private patio near Old Mesilla
This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.
Popular amenities for Mesilla family-friendly rentals
Family-friendly home rentals with a hot tub

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio

Hadley House 1 Bed/ 1 Bath Hot Tub 5 min downtown

Private Oasis Near Old Mesilla with Pool/Jacuzzi!

Heated Pool HotTub GameRoom Views Near White Sands

The Ritz Spa Sanctuary hot tub/patio/fam/pet

Home in Las Cruces Casa de Flores (Flower House) Near NMSU

Apache’s Retreat w/ HOT TUB & Pool table

Pecan Palace – Luxe 4BR w/ Hot Tub, Game Room & EV
Family- and pet-friendly home rentals

"Casa de Maíz" centrally located - close to NMSU

The Adobe Escape and Sauna

* Double Decker Shipping Container Home

Beautiful Adobe Home

Hacienda de Napoleon in Mesilla. Small house with 2 bedrooms.

Amazing Historical Bungalow-NMSU, Mesilla

King Bed |Spacious house |Pets OK

Oasis Crosses | Movie Theater| 3BR
Family-friendly home rentals with a pool

Luxury Home- Pool, Views, Early Check in

[Pool open] Nature Retreat 12-min from Downtown

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Sancho's Condo in Mesilla

95° Heated Saltwater Pool | Desert Views | Pets OK

Desert Peaks Casita

Clara's Nest - The Gem of Hacienda de Las Cruces

Desert Pool Oasis-Central Location-Family Friendly
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £94 | £92 | £92 | £85 | £92 | £92 | £85 | £86 | £77 | £89 | £92 | £93 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Quick stats about holiday rentals that are family-friendly in Mesilla

Total holiday rentals
Explore 40 holiday rentals in Mesilla

Nightly prices starting at
Mesilla holiday rentals start at £59 per night before taxes and fees

Verified guest reviews
Over 2,390 verified reviews to help you choose

Pet-friendly holiday rentals
Find 20 rentals that welcome pets

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
40 of Mesilla holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests – averaging 4.9 out of 5!
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- White Sands National Park
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- Sun Bowl Stadium
- Western Playland
- New Mexico Farm & Ranch Heritage Museum
- El Paso Zoo
- El Paso Museum of Art
- El Paso Chihuahuas
- Southwest University Park
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- San Jacinto Plaza
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- Sunland Park Racetrack & Casino
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