
House holiday rentals in Mesilla
Find and book unique houses on Airbnb
Quick stats about house rentals in Mesilla

Total holiday rentals
Explore 30 holiday rentals in Mesilla

Nightly prices starting at
Mesilla holiday rentals start at £52 per night before taxes and fees

Verified guest reviews
Over 2,190 verified reviews to help you choose

Family-friendly holiday rentals
20 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
30 of Mesilla holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Mesilla rentals

4.9 Average rating
Mesilla stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated house rentals in Mesilla
Guests agree: these houses are highly rated for location, cleanliness and more.

Modern Hidden Gem- HOT TUB & Organ Mtn Views/Patio
Escape the desert in this beautiful modern home with HOT TUB, exercise room and office space. Relax with the whole family at this peaceful private hidden gem. Enjoy the beautiful NM sunsets and beautiful Organ Mountain View. Children can play on playground and trampoline while you enjoy the fire pit. This is a great space for any work related stay or short relaxed vacation. Conveniently located near US 70 close to White Sands (sleds included) abouand both Red Hawk and Sonoma Ranch Golf Courses!

Desert Oasis with Pool
Pueblo Style home on 1+ Acre with Pool! This charming 4BR/2BA Pueblo Style home features stunning details throughout. Gorgeous saltillo tile in the living areas with beautiful wood beam accents, and a kiva-style fireplace for cozy winter nights. The primary suite offers direct access to the covered patio for summer dips in the pool and evening Sunsets. The 4th bedroom is huge and could be used as a second living area. The pool is not heated but will be open and cleaned all year. Sorry no pets.

Bonita Casita
This is a centrally located, remodeled 2 bedroom, 2 bathroom townhouse, very convenient to HWY 70, a straight shot to White Sands National Park, and Main Street, easy access to Downtown Las Cruces, home to Las Cruces's Farmer's Market. This townhouse features a split and open floor plan, full kitchen with everything you need to prepare a meal, dishwasher, microwave and gas cooking. You will also find an office and outdoor seating area. The property is located very near the lovely 4-Hills Park.

Conway Casita 5-1
Step into your newly renovated one-bed, one-bath haven located at the heart of Mesilla Park. Enjoy a leisurely walk to Picacho Roasters for a delightful coffee experience, or hop on a cruiser bike for a charming ride to historic Mesilla. Immerse yourself in the local ambiance, sipping a drink to the backdrop of live music. As the morning sun rises, take a stroll amidst century-old trees that grace Conway Avenue. Welcome home to a blend of modern comfort and the timeless charm of Mesilla Park.

Historic Adobe Home- Libélula (Dragonfly)
Adobe Libélula (Dragonfly) Historic pueblo-style adobe home & property, complimented with front & rear patios, gazebo, gardens & off-street gated parking. Lovingly renovated 1930 Adobe. Live in the birthplace of Las Cruces. A 5-minute casual stroll to explore and enjoy the origins of Las Cruces, neighborhood restaurants & coffee shops in the Mesquite Historic District, AND museums, shops, a street market off Main St. Las Cruces. Traditional Mexican Décor, Central A/C, WiFi, Smart TV.

Mesilla 1869 Adobe 2 blocks from plaza
I purchased this beautiful home built circa 1869 all Adobe in May 2019 and I want to share it with you! I am living in this home as one of my primary residences but I’m traveling the world and will make it available so you can also enjoy it. Authentic wood beams “vigas” and “latillas”, original kitchen wood floor, painted cement floors (by the previous artist owner), 3 foot thick adobe interior walls. Just steps to the Mesilla Plaza, shops, restaurants!

One bedroom casita in Mesilla Park with hot tub
This unique place has an ambiance all its own. Located a few minute drive from historic old Mesilla and walking distance to a local coffee shop, Mexican restaurant, and a pizza restaurant. Mesilla plaza, and bars are only a few minutes drive away. The building has stainless steel new appliances and dual refrigerated air mini splits, one in the living room, and one in the bedroom. Please note there is a train that occasionally travels near the neighborhood.

Charming Adobe One Block from the Mesilla Plaza
Beautiful, private casita built in the 1930's one block from the plaza. Historic charm with modern conveniences. Perfect for quiet retreat. Fenced flagstone patio in back yard fully equipped with gas grill, outdoor fireplace, outdoor dining area and french doors opening from the house. Large front yard fully enclosed. Full front porch creates shade. This house is peaceful but just steps from the fiestas and activities on the historical Mesilla Plaza.

NEW! 5 Bedroom Mesilla St Charmer- Remodeled!
This newly updated 5 bedroom, 2 bathroom house is located in a quiet neighborhood close to Mesilla, Downtown Las Cruces, NMSU, dining and much more. This little gem is the perfect location for your next Las Cruces stay. This home has 5 bedrooms, all with TVs. Living room has large TV as well. One large bedroom also has a futon to accommodate two more people. The kitchen has seating for 14 total including the island. Enough glass and serve ware for 12.

Modern Accessorized 3-Bedroom
This fully-furnished modern home is perfect for weekend getaways or longterm stays. With latest in appliances and style, the Powder River Villa offers the comfort of home with a luxury feel. Stream Netflix in front of the stacked stone fireplace, decompress in the pebble rain shower, or simply relax on the back porch to the beautiful New Mexico sunsets. This stylish space can be the romantic escape you're seeking or comfortably fit your group of 7.

Sombra Del Valle in Historic Mesilla.
Sombra Del Valle is a beautiful home located in a quiet neighborhood and within 5 minute walking distance to the historic Mesilla plaza and 2 minute walking distance to a Brewery and restaurant and approximately 5 minute drive to NMSU. The home is comfortable and spacious; great for family trips, honeymoons, or just a fun getaway. There is free guest private parking. Once you stay here you will want to come back; it’s a home away from home.

Home in Las Cruces Casa de Flores (Flower House) Near NMSU
Casa de Flores is a warm and cozy, good sized, pet friendly 3 bdrm, 2 bath house. Has a great outdoor living space with a covered, always working, heated hot tub. Ideal for short or long term stays. Fully stocked kitchen. High speed Internet. Water Softener. Great location!! Near hospitals, NMSU, Old Mesilla, mall, Downtown Main Street, several restaurants, grocery stores, local breweries and minutes away from highway access.
Popular amenities for house rentals in Mesilla
House rentals with a pool

Briarwood Place (with Game Room and Pool)

Luxury Home- Pool, Views, Early Check in

Casa Venus luxury gem w/arcade 50m to White Sands

Pet Friendly Luxury Retreat W/ Heated Pool & Spa

Private Oasis Near Old Mesilla with Pool/Jacuzzi!

Luxury Oasis Best Location • PingPong • CoffeeBar

Mesilla Estates with a pool

Year Round Heated Pool, Fast Wifi, Pet Friendly
Weekly house rentals

Near Old Mesilla, NMSU, spacious yard

Casa Mesilla

Beautiful Adobe Home

Haciendas de Horacio 3 bedrooms w/2 king beds.

Charming 1930 home near NMSU/ Mesilla

Luxury Southwest Retreat

King Bed |Spacious house |Pets OK

Apache’s Retreat w/ HOT TUB & Pool table
Private house rentals

Luxury on pecan farm

Rustic SouthWest Retreat | 4BR| Desert Charm

Cozy 2 bedroom home in the heart of Picacho Hill

Hidden Las Cruces Retreats

Cozy Las Cruces Home

Cielito Downtown

Charming Adobe Casita in Old Mesilla - near NMSU

Pet Friendly, EV Charger, Near NMSU, DT, & Golf
When is the best time to visit Mesilla?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £93 | £91 | £90 | £86 | £93 | £93 | £75 | £81 | £75 | £75 | £93 | £94 |
| Avg. temp | 4°C | 7°C | 10°C | 14°C | 19°C | 25°C | 27°C | 25°C | 22°C | 15°C | 9°C | 4°C |
Destinations to explore
- Family-friendly rentals Mesilla
- Rentals with a patio Mesilla
- Rentals with a fireplace Mesilla
- Rentals with outdoor seating Mesilla
- Rentals with pools Mesilla
- Rentals with a washing machine and dryer Mesilla
- Pet-friendly rentals Mesilla
- Rentals with a firepit Mesilla
- House rentals Doña Ana County
- House rentals New Mexico
- House rentals United States
- White Sands National Park
- Sun Bowl Stadium
- Wet 'N' Wild Waterworld
- Franklin Mountains State Park
- El Paso Zoo
- La Rodadora Espacio Interactivo
- El Paso Chihuahuas
- El Paso Museum of Art
- San Jacinto Plaza
- Farmers And Crafts Market of Las Cruces
- New Mexico Farm & Ranch Heritage Museum
- Sunland Park Racetrack & Casino
- Dripping Springs Natural Area
- Western Playland
- Southwest University Park
- Plaza Theatre
- Memorial Park
- Casa de Juan Gabriel
- Mesilla Plaza
- Museo de la Revolución en la Frontera
- Chamizal National Memorial





