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Pet-friendly holiday rentals in Mesilla

Find and book unique pet-friendly homes on Airbnb

Top-rated pet-friendly home rentals in Mesilla

Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

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Guest favourite
A covered outdoor seating area is illuminated by string lights, creating a warm ambiance for evening relaxation. Comfortable seating is arranged around a central fire table, while a hammock is visible nearby. The space features a combination of brick and stone textures.
Townhouse in Las Cruces
4.96 out of 5 average rating, 302 reviews

The Ritz Spa Sanctuary hot tub/patio/fam/pet

Come unwind and rejuvenate at our zen sanctuary, where relaxation, simplicity, and comfort are key to a great stay! Pamper yourself in our spa like walk-in rain showers! Enjoy our newly remodeled contemporary interiors with natural terrecota concrete throughout. Private patio enjoy grilling with friends and family or spend a romantic evening sitting around the fire table or in the Hot tub! NMSU 5mi, White Sands 45mi, Less than 1 min access to Hwy-70, I-10,I-25 Old Mesilla 5mi, sec to Hospital

Top guest favourite
A welcoming porch features two light blue chairs positioned beside a rustic table under a wooden beam ceiling. A ceiling fan hangs above, and a colorful door adds a touch of character. A dried chili pepper wreath decorates the entryway, enhancing the outdoor oasis.
Guest house in Mesilla
5 out of 5 average rating, 238 reviews

Ocotillo Casita in Historic Mesilla.

Mesilla STR Permit #0830 We've renovated 90-year-old historic structures to create sustainable, environmental friendly spaces with rainwater harvesting, solar energy, electric solar-powered car charger. This renovated adobe casita is the 2nd structure after our main house. The 3rd is a smaller vacation rental called Yucca Casita. We are within 2 blocks of the historic Mesilla plaza with its farmers market, shops, galleries, restaurants, and walking trails along historic acequias (canals).

Top guest favourite
Guest house in Las Cruces
4.96 out of 5 average rating, 145 reviews

1 king bd with big fenced back yard pets welcome

Casita La Pacana is nestled in the middle of town surrounded by old pecan trees. Feels like the country but is in the middle of town. 1 bedroom, completely renovated casita that has 1 kind bed, a large living room, streaming TVs in both living room and bedroom, full kitchen including a dishwasher and washer/dryer, hardwood floors, authentic Talavera tile, large shower with a bench seat, huge back yard, and ample parking! This little casita has everything to be your home away from home.

Guest favourite
An interior space showcases wooden accents and a warm ambiance. A dining table with vintage-style chairs is set for guests, featuring tableware arranged neatly. Various mirrors reflect natural light from skylights above, while unique windows with shutters add character to the room.
Camper van/Motorhome in Las Cruces
4.96 out of 5 average rating, 111 reviews

The Stranded Time Traveler; a timeless experience!

Like something out of a fairy tale, the time machine's beauties are enchanting and memorable. Set somewhere in the past and present, it is being held in a large storage yard (plenty of space) because of flux capacitor issues while time marches on. Centrally located, it is about 3 mins. from NMSU, 5 mins. from Old Mesilla, the Billy the Kid court house, and the Farmers Market, 20 mins. from Dripping Springs Natural Area, 40 mins from El Paso, and 45 mins. from White Sands National Park.

Top guest favourite
A vibrant yellow casita is framed by a rocky landscape and native vegetation. Large windows and a covered porch are visible, inviting natural light. The casita's exterior showcases a blend of rustic charm and modern design, set against a clear blue sky.
Guest house in Las Cruces
4.98 out of 5 average rating, 199 reviews

Raven's House

Casita De Cuervo is a beautiful detached casita. This spacious & quiet casita is very close to popular hiking trails and feels remote while being less than 15 minutes from I-25, NMSU, and both hospitals. This home has a full kitchen, king bed, open living room, work nook, bar stool dining, & much more. Dogs are welcome - there is an enclosed side yard with tall walls for your use. Enjoy the sunrise over the Organ Mountains on the back porch and breathtaking sunset views over the city.

Guest favourite
The exterior of the remodeled 1940s limestone brick home is showcased, featuring a well-maintained patio area with a stone pathway. A flower bed filled with pink blooms adds color, while nearby greenery and a stone wall create a private atmosphere. Clear skies overhead enhance the inviting setting.
Bungalow in Las Cruces
4.93 out of 5 average rating, 296 reviews

Amazing Historical Bungalow-NMSU, Mesilla

Welcome to our beautiful 1940’s historical University-house that lives in the heart of Las Cruces. While this adorable home is the perfect private getaway for you and the family, its location makes it easy for you to get around; Walkable to NMSU, Dining, Brewery, Starbucks and nightlife. -2 blocks to NMSU, Performing arts, Convention Center. -5 mins to Old Mesilla village, Downtown Las Cruces. -55 mins to White Sands National Park Free EV Level 2 charging Pets welcome Love Kids

Guest favourite
The modern townhouse exterior features a neutral-toned facade with a tiled roof. A single door is positioned at the front, accompanied by a smaller side window. A driveway leads to a garage, and gravel landscaping extends towards the door, under a clear blue sky.
Townhouse in Las Cruces
4.94 out of 5 average rating, 496 reviews

Cul-de-sac Condo

You'll enjoy staying in this modern townhouse enjoy a glass of wine in the covered patio while taking in the New Mexico sunsets. Pet free, smoke free. Fully equipped kitchen with everything you'll need to prepare meals. Spacious 2 bedrooms , 2 full bathrooms. Smart TV's with Roku, access to garage, washer/ dryer. In friendly quiet cul de sac neighborhood with minimal traffic. Easy access to Interstates 10, 25, and Highway 70. Close to restaurants, movie theater, shopping.

Top guest favourite
The exterior of the guesthouse features a welcoming entrance with a turquoise door framed by two wooden columns. A small seating area with two chairs is positioned on the porch, accompanied by potted plants and a tiled floor. The sky above displays a gentle blend of blue and white hues.
Guest house in Mesilla
4.97 out of 5 average rating, 395 reviews

Getaway Guesthouse in Historic Mesilla

Welcome to our cozy guesthouse, just a few blocks away from the Historic Mesilla Plaza. You'll find unique shops, restaurants, bars, and art markets nearby, offering a delightful experience for all your senses! The mouth-watering scents of Chala's Wood Fired Grill and Spotted Dog Brewery will entice you, as they're just around the corner. You'll also hear the bells from one of the oldest churches in the area and enjoy live music from the neighborhood's restaurants and bars.

Top guest favourite
A single-story home showcases a traditional adobe exterior with a tiled roof. A well-maintained front yard features low-maintenance landscaping, including gravel, shrubs, and rocks. The driveway leads to a two-car garage, and a covered porch adds an inviting touch to the entryway.
Home in Las Cruces
4.99 out of 5 average rating, 195 reviews

"Casa de Maíz" centrally located - close to NMSU

"Casa de Maíz" is a quaint home close to New Mexico State University, the Las Cruces Convention Center, and has access to downtown and Historic Mesilla. The home is in a quiet neighborhood close to a park where you can take your children or your dog(s). The home is a perfect stop on a cross-country trip or a place for temporary housing. The sunsets from the backyard are breathtaking. You will be inspired to go hiking while viewing the Organ Mountains from the front yard.

Top guest favourite
A cozy interior space features a queen bed with a bright yellow throw pillow. A kitchenette with a microwave, mini-fridge, and sink is present. Natural light filters through the windows, which are adorned with blue curtains. A small table and chairs complement the room's design.
Guest house in Las Cruces
4.97 out of 5 average rating, 362 reviews

Cozy Casita w/private patio near Old Mesilla

This adorable casita is located just one mile from Historic Mesilla and 5 min from the interstate. The one bedroom 1 bath casita is perfect for visitors and travelers alike. Furnished with a queen bed, table and chairs and a outfitted kitchenette with microwave/air fry toaster oven/Keurig /double hot plate/ sink and mini-fridge. Also includes Wi-Fi , Smart TV (no cable), mini-split AC/ heater, and a private outdoor patio table and gas grill.

Top guest favourite
A charming casita features a turquoise door and a light exterior, framed by subtle landscaping. The sky is filled with vibrant orange and yellow hues as the sun sets, creating a striking contrast against the white walls and windows.
Guest house in Mesilla
4.99 out of 5 average rating, 222 reviews

Cozy Casita De Mesilla (Mesilla Cottage)

Cozy casita just steps from Old Mesilla’s historic plaza and coffee shops. Unwind in your private courtyard with a hot tub, or curl up by the fireplace inside the guesthouse. A kitchenette adds comfort for longer stays. Mesilla Bosque State Park by the Rio Grande is only 4 minutes by car—or a short bike ride—perfect for birdwatching, sunsets, and peaceful walks. The ideal spot for a romantic getaway or quiet retreat.

Top guest favourite
A welcoming living area features a modern design with a sectional sofa, a sleek coffee table, and a flat-screen television mounted on an embellished wall. A textured white fireplace serves as an elegant focal point, complemented by a decorative mirror and natural greenery in the corner.
Home in Las Cruces
4.95 out of 5 average rating, 190 reviews

New Modern/Cozy Spacious Home

Find comfort in this new home in a safe neighborhood! Stylish place to stay and is perfect for group or family trips. Fast wifi and a working space make it the perfect staycation for business travelers. Spacious 3 bedrooms, 2 baths can sleep up to 6 people. Enjoy cooking in the gourmet kitchen. Snuggle up next to the beautiful white quartz fireplace or sit on the patio to view the mountains at sunset.

Popular amenities for Mesilla pet-friendly home rentals

When is the best time to visit Mesilla?

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Avg. price£77£74£81£74£82£82£73£74£67£74£82£82
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Quick stats about holiday rentals that are pet-friendly in Mesilla

  • Total holiday rentals

    Explore 40 holiday rentals in Mesilla

  • Nightly prices starting at

    Mesilla holiday rentals start at £37 per night before taxes and fees

  • Verified guest reviews

    Over 3,030 verified reviews to help you choose

  • Family-friendly holiday rentals

    20 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    20 properties have a dedicated workspace

  • Wifi availability

    30 of Mesilla holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mesilla rentals

  • 4.9 Average rating

    Mesilla stays are highly rated by guests – averaging 4.9 out of 5!