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Holiday rentals in Panama Canal

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Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 223 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Flat in Panamá
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 5 reviews

Large Apartment in La Cuadra - Casco | By Alura

El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Guest favourite
Flat in Panamá
4.9 out of 5 average rating, 20 reviews

Casco Viejo / Penthouse w/ Terrace & Pool Access

Nuestro Penthouse, en el último piso de La Cuadra Residence, en Casco Antiguo, cuenta con terraza privada con vista al Océano Pacifico y su entrada al Canal de Panamá, Cerro Ancón, Casco Antiguo, Cinta Costera, Biomuseo, Puerto de Cruceros de Amador y el skyline de la hermosa Ciudad de Panamá. Contamos con acceso privado al área social y piscina, desde nuestra terraza. Nuestro Lobby cuenta con acceso privado al restaurante Ayala Vida, de autentica comida panameña.

Guest favourite
The spacious bedroom features a comfortable queen-sized bed with fresh linens. Light from bedside lamps creates a soft glow. Unique tiled flooring adds character, and the slanted ceiling enhances the room's spaciousness. A piece of artwork is displayed above the headboard, contributing to the overall ambiance.
Flat in Panamá
4.92 out of 5 average rating, 148 reviews

Perfect Location - Beautiful Apt in Casco Viejo

Peaceful, beautiful and spacious apartment in perfect location. Located in a quiet area of Casco Antiguo, just steps away from lively Plaza Herrera. It cannot get any better, as just across from this unit you have Museo de La Mola, also restaurant Fonda Lo Que Hay and Felipe Motta Wine Store. Downstairs you have one of the best pizzas in the neighborhood. It’s walking distance from the best coffee shops, restaurants, supermarkets, shops, pharmacies and more.

Superhost
Flat in Panamá
4.8 out of 5 average rating, 5 reviews

Modern and cozy central apartment with unique rooftop

LIVE AND ENJOY a unique experience in the heart of Panama City, modern, cozy and fully equipped apartment. Its strategic and central location will allow you to move around easily and get to know THE BEST OF PANAMA. Restaurants, shopping centres, supermarkets, pharmacies, hotels and main tourist attractions, all within minutes. Ideal for tours, remote work, or short and long stays. Here you'll find comfort, design, spectacular views and an unforgettable stay.

Top guest favourite
Flat
4.95 out of 5 average rating, 19 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 12 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
Flat in Panamá
5 out of 5 average rating, 5 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Live the "Cinta Costera Vibes" experience 🌴 from this modern studio apartment with a panoramic view of the Bay and the vibrant Balboa Avenue. Perfect for travelers looking for comfort, style, and a premium location. Enjoy the pool, restaurant, gym, and rooftop with the best sunset in Panama 🌅. Ideal for short or long stays — your home with home warmth and a 5⭐ touch. Save it as a favorite and live the Host Up experience!

Guest favourite
A modern living area features a soft beige sofa facing a flat-screen TV mounted on a textured stone wall. Large glass doors provide a view of vibrant city buildings and the coastline, allowing natural light to illuminate the space.
Apartment in Panamá
5 out of 5 average rating, 32 reviews

180° Old Town Views, Pool & Coworking

☆ What our guests are saying: "The view was astonishing." "It is clean, quaint, and cozy." "I truly felt safe, and it was very modern." "No one can beat this treatment Chef kiss". ☆ Early check-in is available! AMENITIES: ☆ Salt-water pool. ☆ Comfy coworking space with free wifi. ☆ High-speed elevators. ☆ Bicycle rental is available in the lobby. ☆ Parking space (extra fee applies). ☆ Lobby concierge and 24/7 security.

Top guest favourite
A modern living space features a light-colored sofa accompanied by a round coffee table. A large television is mounted on a decorative wall behind the sofa. Natural light streams through tall windows dressed with sheer curtains, enhancing the cozy atmosphere.
Flat in Panamá
4.93 out of 5 average rating, 60 reviews

Elegant apartment with a view & the warmth of home

This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of ​​the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Top guest favourite
Flat in Panamá
4.99 out of 5 average rating, 128 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Popular amenities for Panama Canal holiday rentals

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