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Holiday rentals in Panama Canal

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Panama Canal

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Flat in Panamá
4.8 out of 5 average rating, 5 reviews

Apto céntrico moderno y acogedor con rooftop unico

VIVE Y DISFRUTA una experiencia única en el corazón de la ciudad de Panamá, apartamento moderno, acogedor y totalmente equipado. Su ubicación estratégica y céntrica te permitirá moverte fácilmente y conocerTODO LO MEJOR DE PANAMA. restaurantes, centros comerciales, supermercados, farmacias, hoteles y principales atracciones turísticas, todo a minutos. Ideal para tour, trabajo remoto o estadías cortas y largas. Aquí encontrarás comodidad, diseño, vistas espectaculares y una estadía inolvidable.

Top guest favourite
A communal rooftop space is revealed, showcasing several white-accented chairs and small tables arranged amidst potted plants. The backdrop features a panoramic view of the Panama City skyline against a clear blue sky.
Flat in Panamá
5 out of 5 average rating, 57 reviews

Tropicool Loft w/rooftop steps from Casco

This historic 1941 loft is located at the entrance of Casco Viejo where you’re steps from the fish market and all the cool cafés, rooftops, and trendy restaurants that make up the neighborhood. Fully equipped kitchen, washer/dryer combo, 1.5 bath, bedroom on 2nd floor, 2 balconies + communal rooftop, projector w/Netflix, fast internet, and great AC. You’re also directly in front of the Cinta Costera park for running, biking, tennis courts. Near local airport for flights to Bocas!

Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 223 reviews

En el corazón de Casco, remodelado y con parking

Escápate y descubre casco antiguo en este remodelado , cómodo y céntrico alojamiento en el corazón de Casco Viejo. Nuestra ubicación es lo mejor, te hará regresar. Cerca de restaurantes, Bares, Impresionantes Iglesias y Museos. La propiedad data del siglo XVII (1756) historia y buen ambiente. Podrás explorar la zona a pie, cocina full equipada, cama king europea, te sentirás como en casa, rodeado de las famosas paredes de calicanto. -Amplia sala de estar -Cocina full equipada

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 5 reviews

Amplio Apartamento en La Cuadra - Casco | By Alura

El Casco Antiguo de Panamá es uno de los barrios más encantadores y vibrantes de la ciudad. Declarado Patrimonio de la Humanidad por la UNESCO. El Apartamento El espacio combina líneas modernas con detalles originales del barrio. Cuenta con una distribución luminosa, cocina equipada, sala amplia y acabados pensados para brindar comodidad. Posee un dormitorio con cama king y un hermoso balcón. Es ideal para quienes buscan vivir una experiencia auténtica en el Casco Antiguo.

Guest favourite
Flat in Panamá
4.9 out of 5 average rating, 20 reviews

Casco Viejo / Penthouse w/ Terrace & Pool Access

Nuestro Penthouse, en el último piso de La Cuadra Residence, en Casco Antiguo, cuenta con terraza privada con vista al Océano Pacifico y su entrada al Canal de Panamá, Cerro Ancón, Casco Antiguo, Cinta Costera, Biomuseo, Puerto de Cruceros de Amador y el skyline de la hermosa Ciudad de Panamá. Contamos con acceso privado al área social y piscina, desde nuestra terraza. Nuestro Lobby cuenta con acceso privado al restaurante Ayala Vida, de autentica comida panameña.

Guest favourite
The spacious bedroom features a comfortable queen-sized bed with fresh linens. Light from bedside lamps creates a soft glow. Unique tiled flooring adds character, and the slanted ceiling enhances the room's spaciousness. A piece of artwork is displayed above the headboard, contributing to the overall ambiance.
Flat in Panamá
4.92 out of 5 average rating, 148 reviews

Perfect Location - Beautiful Apt in Casco Viejo

Peaceful, beautiful and spacious apartment in perfect location. Located in a quiet area of Casco Antiguo, just steps away from lively Plaza Herrera. It cannot get any better, as just across from this unit you have Museo de La Mola, also restaurant Fonda Lo Que Hay and Felipe Motta Wine Store. Downstairs you have one of the best pizzas in the neighborhood. It’s walking distance from the best coffee shops, restaurants, supermarkets, shops, pharmacies and more.

Top guest favourite
Flat
4.95 out of 5 average rating, 19 reviews

Gorgeous Flat in the best location in Casco Viejo

This cute and stylish studio is perfectly located in the heart of Casco Viejo, Panama City’s most charming historic district. Recently renovated, it combines modern comfort with classic charm inside a beautiful colonial building—just steps from top restaurants, bars, monuments, and attractions. The space includes a comfortable sofa bed, making it ideal for a couple or a small family looking to enjoy the vibrant atmosphere of Casco right outside their door.

Top guest favourite
Flat in Panamá
5 out of 5 average rating, 12 reviews

Private parking & rooftop | Studio Casco Center

This beautiful restored studio from the 1870s blends history with modern design. Enjoy a private rooftop terrace with seating and BBQ, plus private PARKING—ideal after exploring Casco's best restaurants, galleries, and nightlife steps away. ✨ Highlights: - Historic Charm: Original tile floors and exposed colonial stone walls. - Comfort: King bed, living room, and full kitchen. - Amenities: Private rooftop & private PARKING. - Great location

Guest favourite
Flat in Panamá
5 out of 5 average rating, 5 reviews

Cozy Studio in Cinta Costera with Home Vibes

✨ Vive la experiencia “Cinta Costera Vibes” 🌴 desde este moderno apartaestudio con vista panorámica a la Bahía y a la vibrante Avenida Balboa. Perfecto para viajeros que buscan confort, estilo y ubicación premium. Disfruta piscina, restaurante, gimnasio y rooftop con el mejor atardecer de Panamá 🌅. Ideal para estancias cortas o largas — tu hogar con calor de hogar y toque 5⭐. ¡Guárdalo como favorito y vive la experiencia Host Up!

Guest favourite
A modern living area features a soft beige sofa facing a flat-screen TV mounted on a textured stone wall. Large glass doors provide a view of vibrant city buildings and the coastline, allowing natural light to illuminate the space.
Apartment in Panamá
5 out of 5 average rating, 32 reviews

180° Casco Viejo Views, Pool & Coworking

☆ What our guests are saying: "The view was astonishing." "It is clean, quaint, and cozy." "I truly felt safe, and it was very modern." "No one can beat this treatment Chef kiss". ☆ Early check-in is available! AMENITIES: ☆ Salt-water pool. ☆ Comfy coworking space with free wifi. ☆ High-speed elevators. ☆ Bicycle rental is available in the lobby. ☆ Parking space (extra fee applies). ☆ Lobby concierge and 24/7 security.

Top guest favourite
A modern living space features a light-colored sofa accompanied by a round coffee table. A large television is mounted on a decorative wall behind the sofa. Natural light streams through tall windows dressed with sheer curtains, enhancing the cozy atmosphere.
Flat in Panamá
4.93 out of 5 average rating, 60 reviews

Elegant apartment with a view & the warmth of home

This apartment with the warmth of home, elegant and comfortable with spectacular views of the city, located in one of the best areas of Panama City, surrounded by places of interest such as restaurants, commerce and the most important banking area of ​​the city, and its proximity to the Iglesia del Carmen metro station provides easy transportation in and out of Panama City.

Guest favourite
An inviting lobby area features modern furniture with plush white chairs arranged around a circular table. The wall is adorned with a text sign that reads 'La Cuadra.' Decorative plants add a touch of greenery to the stylish space, complemented by patterned flooring.
Flat in Panamá
4.87 out of 5 average rating, 116 reviews

Hermoso apart en Casco Viejo

Ubicado en el corazón de Casco Viejo, podrás disfrutar el atardecer con vistas a la ciudad, al mar y al canal, desde su rooftop. En planta baja del edificio alberga La Cuadra Market en el cual hay una variedad de restaurantes de renombre con diferentes estilos de comida, así como un bar. Cerca de todo, puedes recorrer todo caminando y disfrutar cada lugar que te ofrece.

Popular amenities for Panama Canal holiday rentals

Destinations to explore

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  2. Panama
  3. Panama Canal