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Holiday rentals in Rochester

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Top-rated holiday rentals in Rochester

Guests agree: these stays are highly rated for location, cleanliness and more.

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Home in Rochester

4.86 out of 5 average rating, 104 reviews

Relaxation Station 0.7 Miles from Mayo King Bed

Your home away from home awaits! With 3 bedrooms, 1 bath, kitchen, living room, office space, and laundry room (all newly renovated), this home is perfect for you! A large backyard and patio, easy access to miles of walking trails and a park right across the street makes this home great for relaxing outdoors. Conveniently located 0.7 miles from downtown and Mayo makes it a perfect stay for guests visiting the clinic or other Rochester events. We look forward to warmly welcoming you to Rochester!

Guest favourite

Home in Rochester

4.92 out of 5 average rating, 215 reviews

Home Calls the Heart- 10min to Mayo

1/2 block from HWY 52, serene and peaceful split level home. 10 min to Mayo Clinic & St. Mary's Hospital. Fully furnished, convenient and ideal for families and professionals for the home away from home feel. Luxury Sheets & Posturepedic beds. Reasonable Mall of America drive. Fully equipped with various kitchen appliances and utensils. Minutes to parks, groceries, Walmart, Target etc. Wifi, Roku Smart TV & cable. Phone call away if you have any issues while staying at our charming home.

Home in Rochester

4.92 out of 5 average rating, 165 reviews

St. Augustine Cottage, WALK St Marys/Mayo Clinic

Warm, cozy, centrally located home just yards from St Mary’s Hospital (hospital in background of pic) in the prestigious “Pill Hill” neighborhood. From St Mary’s catch the free Mayo Shuttle to other Mayo buildings. ****The home is a Duplex.*** Walkable to everywhere. Save money and hassle on parking! Features all hardwood floors, remodeled kitchen and bath, leather couch, smart tv and WiFi, high quality linens and Pottery Barn comforters. Garage parking available for a midsize vehicle.

Guest favourite

Home in Rochester

4.94 out of 5 average rating, 211 reviews

Euro House, Bright! Near Mayo-Single Family Home

Welcome to our private single family home designed by local architect Harold Crawford, located in a quiet neighborhood close to the Mayo Clinic, parks, & restaurants. The backyard is a master gardeners dream space, filled with native plants & outdoor seating. 2 queen bedrooms & 2 full baths. Off street parking for 1 vehicle, plenty of street parking. Wi-Fi, cable, smart TV's, washer & dryer included. Pet free, Clean and Modern home away from home. 5 minutes / .9 miles from Mayo Clinic!

Rental unit in Rochester

4.87 out of 5 average rating, 139 reviews

NEW: Calming main floor retreat near Mayo Clinic

• Enhanced cleaning protocols due to COVID • Fully renovated apartment in winter 2019 • Main floor apt in quiet 4plex • 550 square feet with refinished hardwood floors throughout • La-Z-Boy power recline loveseat with power headrests and USB ports. Both sides also rock. • 65" Smart TV with DirecTV • Free off-street parking • 6 blocks north of Mayo Clinic • Walk-in shower • Queen bed • Full kitchen with gas stove and dishwasher • High-speed WiFI — 100+ MBPS • Shared laundry in basement

Guest favourite

Home in Rochester

4.98 out of 5 average rating, 136 reviews

Spacious Modern Home Near Mayo, St. Mary's Campus

- 5 min walk to Mayo Clinic, St. Mary’s campus - 3 bedrooms, 3 bathrooms, and a loft - unique design with vaulted ceiling and skylights in the style of Frank Lloyd Wright, one of its kind in the whole neighborhood - two-car garage + another dedicated parking space outside - walkable and safe family-friendly neighborhood close to downtown and all amenities - outside front and back patios - fusball play table - dedicated workspace - high speed wifi - Apple TVs - washer and dryer

Guest favourite

Home in Rochester

4.97 out of 5 average rating, 156 reviews

The BEST Stay in Town: See Pics+Reviews to Believe

One level living/no stair. One-side of a duplex home: 1,200 Squarefeet w/ your own private entry, parking, laundry, kitchen, etc. 2 miles to Mayo, Target, Hyvee, gas stations...Fully furnished home. Smart TV & Fridge w/ Superfast internet & NetFlix included. Easy self-check-in keypad. A few blocks to the bus stop. Modern/spacious interior. Fully equipped kitchen w/ dishwasher, pots, pans, and washer/dryer at no additional cost. Fireplace & private deck. 3 parking spaces

Rental unit in Rochester

4.82 out of 5 average rating, 177 reviews

EXCEPTIONAL, CONTEMPORARY 2BD/1 BA/ CLOSE TO MAYO

*Following strict CDC guidelines for disinfecting for COVID-19! 4 miles from Mayo Clinic/St. Mary's Hospital. It features a custom kitchen with a large marble island, a large main living area, a 60" TV & DVD player. The Master Suite has a king bed and a separate sitting area. The bathroom has a walk-in shower with a rainfall shower head. Outdoor gas grill/patio, private entrance, washer/dryer combo unit and WiFi also included. Fireplace is NOT available for guests use.

Guest favourite

Home in Rochester

4.88 out of 5 average rating, 262 reviews

Mayo Downtown's Prairie Home Retreat

Nestled in a serene corner, this home offers a perfect blend of tranquility and accessibility; being near the Mayo campus and Rochester's key attractions. Enjoy comfortable beds, a well-appointed kitchen, and a fenced yard with patio gardens. It's an excellent spot for family bonding, featuring three smart TVs, rapid Wi-Fi, and a variety of indoor and outdoor entertainment options. We strive to accommodate flexible check-in/check-out arrangements whenever feasible.

Guest favourite

Rental unit in Rochester

4.93 out of 5 average rating, 134 reviews

Home for the Traveler, a walk to St. Mary's

This unit is located near the heart of Rochester, within blocks of St. Mary's hospital. This is a lower-level unit in an older home, and includes a gorgeous bedroom with a gas fireplace, a full kitchen, a cozy reading room, and a clean, updated bathroom. This home is also close to the Apache mall, the Canadian Honker and other local restaurants, several coffee shops, and the biking/walking trail system. There is also Wi-Fi, laundry, and parking on-site.

Guest favourite

Guest house in Rochester

4.97 out of 5 average rating, 181 reviews

Hygge House | A Cozy Guesthouse~15 min from Mayo

The Hygge (pronounced hyoo·guh) House is a tiny taste of Scandinavia in Southeastern Minnesota. What is Hygge? In short, it's a Scandinavian way of living that focuses on hunkering down and creating a safe, comforting and warm place to while away. My husband and I hand built the Hygge House with your comfort in mind. We love being cozy and having space to spend together so when the opportunity arose to renovate our studio, we wanted to share it!

Guest favourite

Home in Rochester

4.98 out of 5 average rating, 294 reviews

The Guesthouse Cottage, walkable to Mayo Clinic

Our Guesthouse has a clean cottage feel. King and queen bedrooms offer closets and quality linens. Cook meals in a fully stocked kitchen. Book an Uber, or walk 0.6 miles to Mayo's main Gonda building. We're close to grocers, coffee, parks and trails, and downtown's restaurants, shops, and a lovely public library. Free washer and dryer on site. Cable, internet, BluRay/DVD player. 3-season porch. Small guest garage. No smoking on the property.

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Popular amenities for Rochester holiday rentals

Free parking on premises

Air conditioning

Stay near Rochester's top sights

Apache Mall62 locals recommend

Mayo Clinic36 locals recommend

Walmart Supercenter29 locals recommend

Canadian Honker Restaurant30 locals recommend

Texas Roadhouse6 locals recommend

Costco Wholesale15 locals recommend

Other great holiday rentals in Rochester

Guest favourite

Home in Rochester

5 out of 5 average rating, 33 reviews

Beautifully Designed Space. 1 Mile to Mayo Clinic

Guest favourite

Home in Rochester

5 out of 5 average rating, 20 reviews

The Cozy Hideaway - 6 Minutes from Mayo Clinic

Guest favourite

Cottage in Stewartville

4.94 out of 5 average rating, 16 reviews

Quaint Cottage Surrounded by Nature

Guest favourite

Home in Rochester

5 out of 5 average rating, 34 reviews

Comfy, yellow home, 1 block from St Mary’s Hosp.

Apartment in Rochester

4.93 out of 5 average rating, 15 reviews

Rustic, Cozy Stay + 6 blocks from Mayo!

Guest favourite

Farm stay in Rochester

5 out of 5 average rating, 33 reviews

Lovely county home, on a horse farm, w/ 2 bedrooms

Guest favourite

Home in Rochester

4.96 out of 5 average rating, 76 reviews

Entire Boutique Home Kutzky Park ★ Walk to Mayo ★

Guest favourite

Campervan/Motorhome in Zumbro Falls

4.91 out of 5 average rating, 11 reviews

The Flipping RV: Lake Zumbro

Quick stats about holiday rentals in Rochester

Total rentals
660 properties
Total number of reviews
30K reviews
Family-friendly rentals
430 properties are a good fit for families
Pet-friendly rentals
190 properties allow pets
Rentals with a pool
30 properties have a pool
Rentals with dedicated workspaces
450 properties have a dedicated workspace

Destinations to explore