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Holiday rentals in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,380 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 59,960 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,170 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,180 rentals that welcome pets

  • Holiday rentals with a pool

    2,980 properties feature pools

  • Rentals with dedicated workspaces

    2,510 properties have a dedicated workspace

  • Wifi availability

    4,040 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 14 reviews

Sofisticado 2 Dorm. de Lujo Absoluto

Experiencia de lujo absoluto y sofisticación superior. Este exclusivo departamento de 2 dorms redefine el concepto de confort en Equipetrol, la zona más prestigiosa de SCZ. Cada espacio ha sido cuidadosamente diseñado con mobiliario elegante y una estética refinada que transmite distinción en cada detalle. Exclusivas áreas sociales: 🏊 Piscina 💪 GYM 🎯 Sala de juegos 🌇 Mirador con vista panorámica Ideal para quienes buscan elegancia y una experiencia superior en la mejor zona de la ciudad.

Superhost
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Diseñado para huéspedes de gustos exigentes que buscan una experiencia superior a un hotel 5 estrellas. Ubicado en Equipetrol, la zona más exclusiva y segura de Santa Cruz, este elegante Dpto. en penúltimo piso ofrece doble balcón con vistas únicas! Premium amenities como sky pool, lounge, billar, churrasqueras, gym completo y más! Rodeado de los mejores restaurantes, bares, cafés, teatros, tiendas y centros empresariales. Ideal para viajes ejecutivos, escapadas de lujo o estadías inolvidables.

Top guest favourite
A modern studio apartment is shown with a spacious bed featuring a striped grey and white duvet. A partition defines the sleeping area, while a kitchenette is visible in the background, equipped with dark cabinetry. Two stylish stools and small tables complement the layout.
Flat in Santa Cruz de la Sierra
4.99 out of 5 average rating, 68 reviews

Acogedor departamento de lujo en Equipetrol

Disfruta de una experiencia inolvidable con en este alojamiento nuevo, cómodo y elegante. Hermoso y moderno departamento ubicado en la mejor zona de Santa Cruz. A tan solo pasos de los mejores restaurantes, farmacias, supermercados, bares, discotecas y centros comerciales de la ciudad. Ideal para parejas o viajeros de negocios. Podrás contar con todas las comodidades de un apartamento de lujo para poder pasar una estadía acogedora y agradable. ¡Las áreas comunes del edificio están de sueño!

Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Lujo y confort en cada detalle

Este depto combina lujo, estilo y confort en cada detalle. Diseñado como un hotel boutique, ofrece una experiencia única con acabados impecables, cocina equipada, sala acogedora, dormitorios espaciosos y un hermoso balcón para relajarte. Ubicado en pleno Equipetrol y a pocos pasos de restaurantes, tiendas y atracciones. Perfecto para viajes de negocios o descanso, este espacio moderno y elegante es ideal para relajarte y disfrutar de una estadía inolvidable. ¡Te encantará! Incluye parqueo!

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 5 reviews

Hermoso, Amplio y Único Dpto. en la mejor zona.

Crea recuerdos inolvidables en este alojamiento único y familiar. Excepcional dpto. de 122 m2 en el corazón de Equipetrol. Lugar muy tranquilo para descansar o trabajar, pero a la vez cerca de la diversión. Pasarás una increíble estadía! Dpto. amplio, moderno, amoblado y decorado, A/C, Wifi, Smartv 4k 65' y 55', cocina, 2 dormitorios, 3 baños, área de lavado y secado propio, amplio parqueo gratuito en la entrada las 24 horas. Hermosa Piscina y sauna. Gran balcón con linda vista a la ciudad.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

departamento con excelente vista

Departamento ubicado en la zona de Equipetrol. Situado en el piso 13, disfrutarás de impresionantes vistas en un ambiente cómodo y elegante. Este departamento cuenta con dos habitaciones y dos baños, ideal para familias o grupos. Está completamente equipado para que te sientas como en casa. Entre las amenidades del edificio, encontrarás un cine, una piscina, un área de churrasco, gimnasio equipado, área de juegos, parqueo para visitas. Acceso fácil a restaurantes, tiendas y atracciones.

Guest favourite
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 25 reviews

POX: Green Tower piso 16 | Lujo y elegancia - 2H

¡Vive la experiencia POX! Te presentamos nuestro departamento más grande en la iconica Green Tower, el edificio más exclusivo y lujoso de Santa Cruz. Un departamento completamente equipado para que vivas una experiencia única con tu familia o amigos. Déjate deslumbrar por la mejor vista de la ciudad, atención 24/7 y cerca de bancos, restaurantes, centros comerciales, todo lo que necesitas a metros de distancia. Nos encargaremos que tengas una estadía formidable, bienvenidos a POX!

Top guest favourite
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 79 reviews

Depto. Premium 3 dormitorios | Piscina |Macororo.

Disfruta de una estadía cómoda y elegante en este amplio departamento de 3 dormitorios en Macororo 13/14, sobre Av. Los Cusis. Ideal para familias, grupos y viajes de trabajo. • Piscina temperada y áreas sociales • Parqueo privado gratuito • WiFi rápido • Cocina equipada • Lavadora y secadora • Smart TV A pocos pasos encontrarás supermercado 24 horas, Starbucks, restaurantes, centro comercial y gimnasio frente al edificio. Un espacio cómodo, seguro y pensado para una excelente estadía.

Guest favourite
A spacious bedroom features a large bed with neutral-toned linens, complemented by bedside tables and soft lighting. Floor-to-ceiling windows frame views of greenery, allowing natural light to fill the room. A simple area rug adds warmth to the polished tile floor.
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 59 reviews

Luxurious stay at modern apartment (Equipetrol)

Astounding apartment furnished to an impeccable standard. It’s the ideal retreat for an exquisite & up-scale stay, located close to the absolute heart of Santa Cruz in one of its finest neighbourhoods. We believe it’s the ultimate location to experience Santa Cruz the way it should be. Get ready to get inspired! Very close to some fabulous sites. All in all, guaranteed enjoyment and relaxation. All day long. Settle in by zoning out with a small company in a professionally cleaned home.

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Lujo Equipetrol

Bienvenido a tu santuario de sofisticación y elegancia en lo alto. Este monoambiente excepcionalmente acogedor y elegante en el 13° piso te invita a experimentar el lujo y la comodidad en su máxima expresión. ¿Estás listo para experimentar la combinación perfecta de sofisticación, comodidad y tecnología? No pierdas esta oportunidad única. ¡Reserva tu estancia en el "13° SmartLife" y déjate seducir por el encanto de este espacio incomparable! Tu refugio urbano te esta esperando.

Guest favourite
Flat in Santa Cruz de la Sierra
4.85 out of 5 average rating, 33 reviews

Penthouse on Avenida Beni

This is the one! Located minutes from restaurants, shopping, and downtown, it doesn't get much more convenient than this! With a fully equipped kitchen, comfortable bedrooms and a cozy environment Step into this apartment and let the cozy surroundings instantly appeal to you! Here you will find everything you need to make this your home away from home. From the thoughtful decor and thoughtful furnishings, this place has been designed to make everyday life beautiful.

Superhost
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 4 reviews

Luxury Studio|GreenTower|Pool & Parking|Equipetrol

Bienvenido a un espacio que combina elegancia y comodidad en el corazón de Equipetrol. Rodeado de cafés, restaurantes con auténticas propuestas gastronómicas. Su ubicación estratégica, te permitirá descubrir con facilidad las mejores zonas de la ciudad. En este loft encontrarás un equilibrio perfecto entre comodidad, estilo y ubicación. Ideal tanto para turismo, una escapada tranquila o un viaje de negocios. Te esperamos para que disfrutes de una estancia única.

Popular amenities for Santa Cruz de la Sierra holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.