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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A modern living area features a comfortable dark leather sofa facing a large flat-screen television. A decorative coffee table sits in front of the sofa, with a potted plant nearby, and the room is illuminated by soft ceiling lights, offering views of the surrounding city through expansive windows.
Apartment
5 out of 5 average rating, 17 reviews

Green Tower - Luxury Apartment

Welcome to the most exclusive address in Santa Cruz—Green Tower. Located in the heart of the city’s top neighbourhood. This high-rise 16th-floor apartment offers breathtaking views over Urubo and Equipetrol. Enjoy a rooftop pool, sauna and top-rated bars and restaurants just an elevator ride away. With 24/7 concierge and security to ensure both comfort and safety throughout your stay. The ideal choice for travelers seeking comfort, privacy and premium access in Bolivia’s economic capital.

Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 152 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 154 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Top guest favourite
A cozy bedroom features a queen-sized bed dressed in light linens and accented by decorative pillows. A piece of wall art hangs above the bed, while a bedside lamp and a small side table provide additional lighting. A comfortable chair is positioned in the corner.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 26 reviews

Hestia Nuu Apartment in Equipetrol

Hestia Nuu en Equipetrol: Hogar, Calidez y Refugio Descubre un oasis de tranquilidad en el corazón de Equipetrol, inspirado en la calidez de Hestia, un balance perfecto entre confort moderno y serenidad. Amplios espacios iluminados, decoración elegante y todo lo necesario para una estadía memorable. Ideal para viajeros de negocios o turistas en busca de un refugio urbano, cerca de restaurantes, centros comerciales y la vida vibrante de la ciudad. Te esperamos con los brazos abiertos!

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 46 reviews

Apartment with good views and Equipetrol Sirari pool

Enjoy the simplicity of this quiet apartment close to the Equipetrol business area. Comfortable and equipped. The building has a small pool, co-working space, terrace with incredible views and parking according to availability with 24-hour security. In addition, the apartment has Wi-Fi, a smart TV, a small balcony, a kitchen, an electric oven, a washing machine and much more. Ideal for single people or couples. It is close to cafes, pharmacies, hospitals, markets, supermarkets and malls.

Top guest favourite
A well-appointed living space features a modern kitchen with wooden cabinetry and stainless steel appliances, including a refrigerator. A cozy seating area with a light gray sofa is arranged beside a spacious bed, while natural light filters through large windows.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 56 reviews

Smart Studio in Equipetrol

Welcome to this great Smart Apartment in the best residential and business area of Equipetrol. You're half a block from Av. San Martin and a short walk from restaurants, shops, bars, and more. The apartment is fully furnished with everything you need for a comfortable stay, including a fully equipped kitchen, air conditioning, Wi-Fi, and a large flat-screen TV. It has a swimming pool, barbecue, co-work rooms and washing machines on the terrace and common areas

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 132 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
A bright living area features a light-colored sofa positioned against a wall adorned with modern art pieces. Natural light enters through large glass windows, illuminating a minimalistic coffee table with a potted plant on top. The space exudes a stylish and contemporary atmosphere.
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 61 reviews

Technology and comfort in one place

Modern apartment located in the best area of the city, surrounded by exclusive restaurants, shops and attractions. Enjoy a rooftop pool with spectacular views, perfect for relaxing, cooling off, and sharing unique moments with your loved ones. The building also has an equipped coworking area, ideal for working, creating, and staying productive during your stay. Book today and experience comfort, style and a prime location!

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 8 reviews

Valentina Suit - Design, comfort and good energy.

Take a break and relax in this quiet oasis located in the best area of Santa Cruz Equipetrol. - Close to Restaurants, Cafes, Supermarket just a few steps away, Ventura Mall, Manzana 40, Green Tower. - Washer and dryer inside the apartment -Wi-Fi - TV in the room and in the living room - Pool and barbecue - Air conditioning in both rooms and heating - Equipped kitchen - Balcony overlooking the street

Guest favourite
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 15 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Guest favourite
A modern building is illustrated at dusk, displaying multiple balconies adorned with greenery. Soft lighting highlights each level, creating a welcoming ambiance. The structure features large windows, enhancing the connection to the outdoors, while the surrounding area includes trees and vehicles.
Apartment in Santa Cruz de la Sierra
4.72 out of 5 average rating, 131 reviews

Nomad Luxury (2 bedrooms)

Located in a modern building, our apartment has all the amenities you could want. Enjoy a pleasant and comfortable experience in the Equipetrol area. Close to supermarkets, restaurants, major shopping malls, among others. The building's social areas have a swimming pool, barbecue, coworking, billiard room, cafeteria service on the ground floor, clothes dryer service, and a rooftop bar.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 31 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Bolivia
  3. Santa Cruz