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Apartment holiday rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Quick stats about apartment rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 580 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 13,180 verified reviews to help you choose

  • Family-friendly holiday rentals

    160 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 190 rentals that welcome pets

  • Holiday rentals with a pool

    500 properties feature pools

  • Rentals with dedicated workspaces

    360 properties have a dedicated workspace

  • Wifi availability

    550 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.8 Average rating

    Santa Cruz de la Sierra stays are highly rated by guests – averaging 4.8 out of 5!

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Top guest favourite
The living area features a comfortable couch positioned near a large window, allowing natural light to fill the space. A flat-screen television is mounted on a wood-paneled wall, and a small round table is visible nearby. The view showcases the city skyline and nearby greenery.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 32 reviews

Luxury, comfort, ideal location

Bienvenidos a la mejor ubicación de Santa Cruz! En el corazón del centro empresarial, pero en una calle tranquila. Supermercados y mucho más a la vuelta de la esquina. A pocos pasos encontrarás decenas de restaurantes increíbles: parrillada, comida japonesa, italiana o americana. Comida rápida o cenas elegantes. Manzana 40 está a 10 minutos a pie. Ventura Mall está a solo 5 min en auto. Ya sea para trabajo o diversión, este es el lugar ideal! El edificio cuenta con personal de seguridad 24/7.

Guest favourite
A modern living area features a comfortable dark leather sofa facing a large flat-screen television. A decorative coffee table sits in front of the sofa, with a potted plant nearby, and the room is illuminated by soft ceiling lights, offering views of the surrounding city through expansive windows.
Apartment
5 out of 5 average rating, 17 reviews

Green Tower - Luxury Apartment

Welcome to the most exclusive address in Santa Cruz—Green Tower. Located in the heart of the city’s top neighbourhood. This high-rise 16th-floor apartment offers breathtaking views over Urubo and Equipetrol. Enjoy a rooftop pool, sauna and top-rated bars and restaurants just an elevator ride away. With 24/7 concierge and security to ensure both comfort and safety throughout your stay. The ideal choice for travelers seeking comfort, privacy and premium access in Bolivia’s economic capital.

Top guest favourite
A cozy living area features a blue sofa adorned with two decorative pillows. A medium-sized round coffee table sits in front, with a book resting on it. Illuminated by natural light from the balcony, a large abstract artwork hangs above the sofa.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 13 reviews

Maximum comfort 3 blocks from the Hotel LosTajibos

Enjoy a pleasant and safe stay in Santa Cruz in our spacious 1-bedroom apartment with panoramic views of the ecological cordon from the 11th floor. Located in the best area of the city, Equipetrol, a safe neighborhood, close to the best restaurants and cafes. Close to supermarkets and pharmacies, two blocks from the Los Tajibos Hotel, Dockweiler Clinic and the Equipetrol business center. The building has a swimming pool, jacuzzi, sauna, gym, barbecue, coworking, etc.

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Apartment in Santa Cruz de la Sierra
4.85 out of 5 average rating, 294 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Guest favourite
Apartment in Centro
5 out of 5 average rating, 5 reviews

oGarden & Balcony + Parking, One Bedroom Apartment

Disfruta de un espacio tranquilo y acogedor, rodeado de verde y luz, cerca del 2º anillo y la rotonda de La Salle. Frente a Starbucks, KFC y DeLicor, con ubicación privilegiada para moverte por la ciudad y a pasos del vibrante barrio Equipetrol. Bienvenido al Condominio La Cañada, donde el diseño moderno se integra con jardines tropicales. Reserva y vive Santa Cruz al máximo. Contamos con parqueo en las instalaciones.

Top guest favourite
An open-concept living area features a modern sofa arrangement alongside a sleek dining table. A light fixture hangs above, while large windows dressed with sheer curtains allow natural light to fill the space. Decorative plants add a touch of greenery.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 32 reviews

Spacious apartment in Equipetrol

Experience the perfect blend of elegance and comfort at our exceptional apartment located in the heart of Equipetrol. With carefully curated decor, this space offers a welcoming and relaxing atmosphere from the moment you step in. Surrounded by the city's finest restaurants, shops, and attractions. Whether you're here for business or pleasure, you'll have access to everything you need for an unforgettable stay.

Guest favourite
A modern bedroom features a spacious bed with light-colored bedding and decorative pillows. Wooden paneling creates a warm aesthetic, complemented by wall-mounted plants. Natural light enters through floor-to-ceiling windows, and a small bedside lamp offers a soft glow.
Apartment in Santa Cruz de la Sierra
4.94 out of 5 average rating, 138 reviews

Modern Studio in the centre of Equipetrol

We offer you a comfortable stady with everything you may need, in this modern and new place with our top quality service. This place is fully furnished and has a beautiful view. Is located in the best area from Santa Cruz, and also near of fancy restaurants, malls and business area. You can have access to building's social areas like: co-work zone, pool, steakhouse and laundry. (pics)

Top guest favourite
Apartment in Santa Cruz de la Sierra
4.95 out of 5 average rating, 21 reviews

Beautiful Apartment In Equipetrol

This unique place is located in Equipetrol; an exclusive, quiet, and safe area of Santa Cruz. It has all the comforts for a pleasant stay, whether for leisure or work trips (wifi and work area). It is 2 minutes from the Ventura Mall and Av. San Martín, where you will find restaurants, cafes, clothing stores, financial institutions, etc.

Guest favourite
Apartment in Santa Cruz de la Sierra
4.87 out of 5 average rating, 119 reviews

New and modern studio in Equipetrol

We put all our work to make a cozy place for guests visiting Santa Cruz de la Sierra. A brand new studio for 3 people. Very well lit. The terrace has a beautiful view of Equipetrol. There is a pool, two churasqueras, and three spaces intended for rooftop meetings, and all located in a very trained and safe neighborhood.

Superhost
A cozy sleeping area is highlighted by a spacious bed dressed in a patterned blanket. Bright pillows add comfort, while natural light flows through a large window. A small table and chair complement the room, alongside a stylish yellow chair and wooden dresser.
Apartment in Santa Cruz de la Sierra
4.88 out of 5 average rating, 130 reviews

Premium Apartment with Panoramic View

Elegant apartment in an excellent location, within the famous Equipetrol neighbourhood, between Avenida Banzer and Avenida San Martín. Ideal for families or groups of friends, with air conditioning, high-speed Wi-Fi and a fully equipped kitchen. Close to many restaurants, supermarkets and shopping centres.

Guest favourite
A well-lit sleeping area features a spacious bed with a soft beige coverlet. Nightstands with lamps are positioned on either side. A full-length mirror reflects the room, while a window above the bed allows natural light to enter. A wardrobe is visible in the corner.
Apartment in Centro
4.88 out of 5 average rating, 169 reviews

Luxury apartment in magnificent area

In the exclusive area of Santa Cruz, 9 blocks from the main square, near supermarkets, pharmacies 24/7, restaurants, cafes, banks, laundry, etc., on the 2nd floor of a new building, elegant apartment, fully equipped. Ideal for travelers visiting us for pleasure or business.

Top guest favourite
A modern studio space features a comfortable sleeping area with a spacious bed, illuminated by soft overhead lighting. A dining area with sleek bar stools and a kitchen counter creates an inviting layout. Large windows provide natural light and a view of the city.
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 49 reviews

Luxurious apt. in the best area of ​​Santa Cruz

Enjoy a stylish experience in this central studio apartment located in the Equipetrol area, it has all the necessary amenities. The location allows you to be close to restaurants, supermarkets, shopping centers, gyms, pharmacies and business centers.

Popular amenities for Santa Cruz de la Sierra apartment rentals

Destinations to explore