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Apartment holiday rentals in Santa Cruz de la Sierra

Find and book unique apartments on Airbnb

Quick stats about flat rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 2,650 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 37,120 verified reviews to help you choose

  • Family-friendly holiday rentals

    680 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 630 rentals that welcome pets

  • Holiday rentals with a pool

    2,050 properties feature pools

  • Rentals with dedicated workspaces

    1,660 properties have a dedicated workspace

  • Wifi availability

    2,520 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

Top-rated apartment rentals in Santa Cruz de la Sierra

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 156 reviews

Studio 518 - Luxury near Everything

Automatic access, 2 Air Conditioners, Washing Machine, Kitchen, Sofa and TV perfect for working all day with a green view from an 8th floor apartment in the most sought-after neighborhood in the city, Equipetrol. If you get bored you can use the pool at no cost, social areas, BBQ. If you get bored, you'll be 2 minutes away from supermarkets, pharmacies, blocks from Equipetrol's main square with renowned restaurants, 5 minutes from the Central Plaza or 5 minutes from Bolivia's largest shopping mall, Ventura Mall.

Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 6 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests looking for an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and safest area of Santa Cruz, this elegant apartment on the penultimate floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecues, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafés, theatres, shops and business centres. Ideal for business trips, luxury getaways or unforgettable stays.

Top guest favourite
Flat in Santa Cruz de la Sierra
4.97 out of 5 average rating, 79 reviews

Spacious 3-bedroom property | heated pool | Macororo

Enjoy a comfortable and stylish stay in this spacious three-bedroom apartment in Macororo 13/14, on Av. Los Cusis. Great for families, groups, and traveling for work. • Heated pool and social areas • Free Private Parking • Fast Wi-Fi. • Equipped kitchen • Washer & Dryer • Smart TV. Just a few steps away, you'll find a 24-hour supermarket, Starbucks, restaurants, a shopping centre and a gym opposite the building. A comfortable, safe space designed for an excellent stay.

Top guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 19 reviews

POX | Green Tower 17th Floor, Luxury in Equipetrol

✨ Live the POX experience of luxury and comfort in the heart of Equipetrol ✨ Located on the 17th floor of the exclusive Green Tower, this POX Glam apartment combines modern design, sophisticated decor and a unique panoramic view of Santa Cruz. Perfect for business travelers, couples, or leisure stays looking for a premium space with all the amenities. At POX we don't just rent apartments: we give you a home away from home. Our team is available 24/7 to help you.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Top guest favourite
A modern studio apartment is shown with a spacious bed featuring a striped grey and white duvet. A partition defines the sleeping area, while a kitchenette is visible in the background, equipped with dark cabinetry. Two stylish stools and small tables complement the layout.
Flat in Santa Cruz de la Sierra
4.99 out of 5 average rating, 69 reviews

Cozy luxury apartment in Equipetrol

Enjoy an unforgettable experience in this new, comfortable, and stylish place. Beautiful and modern apartment located in the best area of Santa Cruz. Just steps away from the city's best restaurants, pharmacies, supermarkets, bars, nightclubs, and shopping malls. Ideal for couples or business travelers. You can count on all the comforts of a luxury apartment to spend a cozy and pleasant stay. The building's common areas are a dream!

Guest favourite
A bright and airy bedroom features a spacious bed adorned with white bedding. Soft, sheer curtains filter natural light from the large window. A bedside lamp provides additional illumination, while a delicate arrangement of orchids adds a touch of elegance to the serene ambiance.
Flat in Santa Cruz de la Sierra
4.86 out of 5 average rating, 22 reviews

Luxury apartment with swimming pool in Equipetrol

Enjoy a luxury experience in this exclusive apartment in the heart of Equipetrol, the best financial and leisure area of ​​Santa Cruz. Close to hospitals, restaurants and cafes, but on a quiet street. Swimming pool, 2 barbecues, gym and chill out area. All social areas with stunning views. You can find more photos, videos and recommendations of places to eat or visit on the Insta account: deluxe santacruz bolivia

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.89 out of 5 average rating, 150 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

Guest favourite
Flat in Santa Cruz de la Sierra
4.94 out of 5 average rating, 17 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Guest favourite
Flat in Santa Cruz de la Sierra
4.96 out of 5 average rating, 47 reviews

Spectacular monoambiente in SkyElite

Enjoy a unique stay in this elegant monoenvironment located in the modern Sky Elite building in Santa Cruz de la Sierra, one block from Los Tajibos Hotel. A space designed to combine comfort, practicality, and a touch of luxury. Its location is excellent, close to restaurants, cafes, shopping centers and the city's main avenues. Ideal for both business trips and break getaways.

Popular amenities for Santa Cruz de la Sierra apartment rentals