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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A serene outdoor space features a large saltwater pool surrounded by multiple lounge chairs and red umbrellas. Lush greenery is visible in the background, providing a tropical setting under a bright blue sky. A hand holds a beverage in the foreground, adding depth to the scene.
Home in Costa Esmeralda
4.98 out of 5 average rating, 201 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 286 reviews

Horizonte Cabin by Casa Amaya

Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.

Guest favourite
Lush palm trees surround the resort-style swimming pools, creating a tropical ambiance. Multiple lounge chairs are arranged neatly near the water, with shaded areas provided by large umbrellas. Pathways lead through landscaped gardens, enhancing the serene outdoor environment.
Flat in Nueva Gorgona
4.94 out of 5 average rating, 124 reviews

Amazing view! Beachfront @Nueva Gorgona Bahia

Luxury Apartment, Ph Bahia Resort, near of Coronado with 2 bedrooms and one with a fascinating ocean view, living room with sofa bed, dining room, kitchen, terrace and 2 full bathrooms. Totally new and with luxury finishes. Building "Resort Hotel" type, with direct access to the beach and 4 private pools, with Restaurant, Snack Bar in the pool area, and a Beach Bar with music at night in front of the sea, with Tennis, Volleyball, Basketball court , playground, billiards, private parking.

Guest favourite
An aerial view reveals a stretch of coastline featuring sandy beaches with a mix of dark volcanic sand and vibrant turquoise water. Lush greenery lines the shore, complemented by residential areas visible in the background, creating a serene and inviting landscape.
Tiny home in San Carlos
4.81 out of 5 average rating, 129 reviews

Cozy beach cabin at Costa Esmeralda.

Cozy private community cabin on a triple space for up to three people located in Costa Esmeralda beach, over the Pacific ocean. Very quiet area with a 2,200 Square meter patio with trees and vegetation. Relax enjoying of the tropical sun, warm temperatures all year long and the ocean breeze. Only 9 minutes away by walk from the closest beach with warm waters and volcanic black sand. 10 minute drive to Coronado (Grocery Stores, restaurants, bakeries, movie theater, malls and much more)...

Superhost
Cabin in Altos del Maria
5 out of 5 average rating, 3 reviews

Fobos – Luxury 1-Bed Cabin with Jacuzzi

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Superhost
The outdoor pool area is surrounded by palm trees and landscaped greenery. A spacious pool features a unique curved design, complemented by a smaller, adjacent soaking area. Lounge chairs are positioned beside the pool, inviting relaxation under the clear blue sky.
Home in Chame District
5 out of 5 average rating, 4 reviews

Country House with Pool + Billiards | Punta Chame

Welcome to our country house, ideal for disconnecting from the daily hustle and bustle and enjoying the tranquility of the natural environment. Surrounded by green landscapes, it combines rustic style with nature, creating the perfect atmosphere for an unforgettable holiday with family and friends. The house has: WiFi, CableTV, Netflix, A/C, Fans, Water Heater, Stove, Kitchen utensils, Refrigerator, Microwave, Oven, Coffee maker, Airfryer and water dispenser. We are Pet Friendly 🐶

Guest favourite
The exterior of the house features a charming design with a red-roofed upper level and a welcoming terrace. A small pool is visible in the foreground, surrounded by lush greenery and natural rock formations. Cloudy skies create a serene atmosphere, enhancing the tranquil setting.
Home in El Nancito
4.94 out of 5 average rating, 33 reviews

Mountain Retreat: Peaceful & Private Escape

Escape to tranquility in our beautiful rural retreat near Laguna de San Carlos, Panama. Nestled on a private hectare of lush land, this cozy two-bedroom, two-bath house boasts an open terrace with breathtaking views of the San Carlos mountains. Whether basking in summer sun or enveloped in clouds during the rainy season, you’ll find peace and beauty here. Just a 30-minute drive to Coronado and the stunning beaches of Panama Oeste, it’s the perfect sanctuary for your getaway.

Guest favourite
An outdoor patio space is presented with wooden chairs and a small table. Lush green grass extends towards the sandy beach, adorned with palm trees and sun loungers under thatched umbrellas, creating a calm coastal view.
Home in Chame
4.83 out of 5 average rating, 94 reviews

P/Caracol Ocean Haven View (C5-PBB) 2 bed, 2 bath

This unique place has a style all its own, steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space and an outside pergola area. (4 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views and great on-site amenities. 1km of beach to offer you the best beach and surfing experience around.

Top guest favourite
A spacious exterior view of the loft @ Londolozi showcases a two-story structure with a red-tiled roof. Large glass doors open to a patio area with lounge chairs and a hammock, surrounded by lush greenery and mountains in the background.
Cottage in Sorá
4.95 out of 5 average rating, 116 reviews

Luxury Private Cottage in Altos del Maria

This property is situated within the gated community of Altos del Maria. Surrounded by lush forest and rivers, the loft @ Londolozi is for guests who appreciate a sense of luxury while being close to nature. While Altos del Maria enjoys a warm tropical climate, there is a cooling breeze in the mountains that is not often present in the coastal areas.

Guest favourite
A panoramic view of the serene coastline is depicted, showcasing several islands in the distance surrounded by calm waters. Luscious green hills lead towards the shore, providing a tranquil backdrop under a subtly overcast sky.
Guest suite in Panamá Oeste
4.83 out of 5 average rating, 105 reviews

Casa Buena Vista

The house is newly built within walking distance to the lookout in the Altos De Campana National Park only 45 minutes from Panama City. With absolutely stunning views it sleeps 4 to make your stay a relaxing, tranquil experience. Bring your own cooler, cook for yourself in a full complete kitchen if you like and enjoy your drinks by the pool.

Top guest favourite
A spacious living area features large windows that provide a view of the ocean. Comfortable seating options include a sectional sofa and armchairs. A round coffee table sits on a textured rug, while ceiling fans circulate air in the bright, airy space.
Apartment in Nueva Gorgona
4.95 out of 5 average rating, 201 reviews

Fabulous Beach Apartment-Ph Royal Palm-Gorgona

FIRST LINE TO THE SEA WITH DIRECT ACCESS TO THE BEACH FROM THE PH POOLS. Fabulous BEACH APARTMENT, Beach Front Unit, comfortable, unique and to relax with the family, it has 4 incredible swimming pools, jacuzzi, sauna, sports courts, board games and access to the beach and restaurant service, coming is not wanting to leave ever

Guest favourite
A pool area is visible with a clear blue pool surrounded by a concrete patio. Two lounge chairs are positioned beside the pool, and greenery from surrounding plants enhances the outdoor space. The area is framed by a shaded overhang, providing a comfortable retreat.
Home in Santa Cruz De Chinina
4.85 out of 5 average rating, 33 reviews

Country House - family Bejuco-Chame

This unique place has its own style. Suitable for celebrating birthdays, projects, working, writing and being totally at peace. Read a good book, give yourself a good pool therapy and share great moments and events with family or couple. In addition to being in an area of cultural experiences.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz