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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A small, rustic structure is positioned amidst a lush, mountainous landscape. A winding gravel road leads towards the building, surrounded by greenery, hills, and trees. The scene is softly illuminated by sunlight, highlighting the natural setting and open space.
Shipping container in San Carlos
4.99 out of 5 average rating, 68 reviews

Justinatinyhouse disconnects to connect

Justinatinyhouse is nestled in the foothills of the San Carlos Lagoon. It has everything you need for your stay with a lot of peace, a cool breeze in the mornings and afternoons, incredible views towards Altos del María, Sorá, Punta Chame, and a dirt road in good condition for any car. It has A/C and everything you need for your stay. It does not have a TV, but there is excellent cell phone coverage. I recommend bringing all the things you need for your food. The nearest store is a 10-minute drive away

Top guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 303 reviews

Horizonte Cabin by Casa Amaya

Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.

Guest favourite
Home in El Higo
4.97 out of 5 average rating, 30 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Top guest favourite
A swimming pool is positioned in the foreground, surrounded by lounge chairs and shaded by umbrellas. The house features a terracotta roof and a hammock hangs near the entrance, with lush greenery and a twilight sky providing a serene backdrop.
Home in Playa Coronado
5 out of 5 average rating, 39 reviews

The Dream of Playa Coronado

Whether traveling to Playa Coronado to relax, spend time with family, flee the cold weather or scout your retirement destination, this house is perfectly located in the heart of Playa Coronado and features an airy, tropical ambience, a pool with loungers to soak up the sun, two bohios with dining/lounging areas, hammocks to sway your day away and a BBQ to cook fresh fish bought at the local fish market. The house has a water well so no problems with access to water during the Dry Season.

Guest favourite
Cabin in Altos del Maria
4.9 out of 5 average rating, 29 reviews

Deimos – Modern Mountain Cabin with Heated Pool

Deimos is a one-bedroom cabin featuring a fully equipped kitchen, a modern bathroom, and a living room that opens onto a private terrace with a jacuzzi. The property consists of a total of three houses, and Deimos is located at the highest point, slightly farther from the others, offering added privacy. The tiny home comes fully equipped with everything needed for a weekend getaway or a longer stay, making it the perfect place to relax and enjoy the amenities of Altos del María.

Top guest favourite
Home in San Carlos
4.91 out of 5 average rating, 163 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Guest favourite
A tranquil outdoor area is depicted, featuring a small private pool surrounded by lush greenery. The charming cottage stands nearby, characterized by large windows and a covered porch that offers ample natural light.
Guest house in Panamá Oeste
4.8 out of 5 average rating, 187 reviews

Mountain cabin with private pool in Panama

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Discount for two nights or more. Close to: Laguna de San Carlos, Valle de Antón, beaches of the Panamanian Pacific.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 268 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Guest favourite
A large swimming pool is surrounded by tropical palm trees, appearing inviting under a clear blue sky. Lounge chairs are positioned around the pool area, providing ample space for relaxation. A portion of the pool is shallow, leading toward a landscaped section with greenery.
Flat in San José
4.85 out of 5 average rating, 170 reviews

B31-Tropical beach paradise, 2R/2B condo, w/pool

Disconnect for a few days from the routine. Have fun with your partner or family in our apartment in Punta Barco Viejo, we have everything you need to be comfortable and have fun in one of the most exclusive areas of the area. We have everything nearby for your best convenience, restaurants, banks, supermarkets ... I´ll deliver a personalized 5 stars attention. Oh and of course, the BEACH 5min by car!

Top guest favourite
Cabin in Panamá Oeste
4.91 out of 5 average rating, 203 reviews

Altos del María Cabin La Loma de Styria

Relax with the whole family at this peaceful place to stay. It is a fantastic, cool and pleasant place where you can do many ecotourism activities, the best option if you want to have one of the best views you can imagine. Great for couples too. We have 2 bedrooms on the 2nd floor and 2 bathrooms. Multiple places to take beautiful photographs

Top guest favourite
A spacious living area is illuminated by natural light streaming through large glass windows. Comfortable seating arrangements are positioned around a circular coffee table, creating an inviting space for relaxation. Scenic mountain views can be seen through the glass, emphasizing the connection with the outdoors.
Cabin in Altos del Maria
4.93 out of 5 average rating, 57 reviews

Blue Sky Lodge; the best view in Altos del María

This luxury mountain cabin offers a modern design, quality finishes, and 180° panoramic views of mountains and sea. It is located in a secure gated community, surrounded by a green garden, with large glass windows that favor connection with nature. The climate is pleasant, with temperatures between 23°C and 28°C. .

Guest favourite
A pool area is visible with a clear blue pool surrounded by a concrete patio. Two lounge chairs are positioned beside the pool, and greenery from surrounding plants enhances the outdoor space. The area is framed by a shaded overhang, providing a comfortable retreat.
Home in Bejuco Chame
4.86 out of 5 average rating, 43 reviews

Country House - family Bejuco-Chame

This unique place has its own style. Suitable for celebrating birthdays, projects, working, writing and being totally at peace. Read a good book, give yourself a good pool therapy and share great moments and events with family or couple. In addition to being in an area of cultural experiences.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz