
Holiday rentals in Santa Cruz
Find and book unique accommodation on Airbnb
Top-rated holiday rentals in Santa Cruz
Guests agree: these stays are highly rated for location, cleanliness and more.

Beach House-Amazing Pool & Jacuzzi - Pet Friendly
Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.
4.98 out of 5 average rating, 222 reviews
Horizonte Cabin by Casa Amaya
Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.
4.94 out of 5 average rating, 319 reviews
The Dream of Playa Coronado
Whether traveling to Playa Coronado to relax, spend time with family, flee the cold weather or scout your retirement destination, this house is perfectly located in the heart of Playa Coronado and features an airy, tropical ambience, a pool with loungers to soak up the sun, two bohios with dining/lounging areas, hammocks to sway your day away and a BBQ to cook fresh fish bought at the local fish market. The house has a water well so no problems with access to water during the Dry Season.
5.0 out of 5 average rating, 43 reviews
Playa Malibu Beach House.
Wake up to the sound of the waves at this beautiful oceanfront home in Playa Malibu, where the beach is literally your backyard. Step outside and enjoy direct beach access, morning walks on the sand, and unforgettable sunsets over the water. The home features a private pool, BBQ area, and an outdoor dining space perfect for shared meals and long, laid-back evenings. Inside, the house offers a cozy, comfortable, and relaxed vibe, with all the essentials for a stress-free stay.
4.95 out of 5 average rating, 44 reviews
Modern House with Great Views and Heated Pool
Modern mountain house in Altos del Maria, Panama, a gated comunity at just 1 hour and 30 minutes away from Panama city. The comunity has rivers, bird watching trails, and is only 25 minutes away from the pacific beaches. Its a perfect place to take a break and relax. The house has a modern decor, infinity pool, 2 bedrooms with A/C, wifi, dishwashing machine, washer and dryer and great view of the mountains. Free late checkout is given for rentals checking out on Sundays.
4.82 out of 5 average rating, 337 reviews
Exclusive Beachfront apartment 1Hour from Pma City
SPECTACULAR FULLY EQUIPPED luxury apartment with 3 bedrooms (all with direct ocean view), 2 full bathrooms and a half guest bathroom; maid's room and bathroom. Fine finishes, 100% stainless steel kitchen and high-efficiency air conditioners throughout the apartment. Condominium with "Hotel Style Living" concept; restaurant and bar for the evenings (Thursday to Sunday), snack bar in the pool area and a Tiki Bar on the beach, as well as a volleyball court, tennis, basketball.
4.96 out of 5 average rating, 184 reviews
Ocean Waves Villa (C6-1D) 2 bed, 2 bath
This unique place is a fully furnished 2 bed/2 bath plus a sofa bed, second floor villa unit has breathtaking ocean views with direct beach access. The unit has a open concept living, dining & kitchen space (6 guests). Unique villa apartment over looking the picturesque Playa Caracol coast with 1km of ocean front and majestic mountain views. Playa Caracol is located on a the beach of Chame and is a newly developed area with expansion for the property and amenities.
4.86 out of 5 average rating, 119 reviews
Summer House
Bring the whole family to this fantastic place with lots of fun areas. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH has a PH pool and a private pool, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, private hospital (emergency). Close to country activities, beaches, mountains, lake. It has a gazebo with all the amenities. The place is safe and complete.
4.94 out of 5 average rating, 67 reviews
Villa Acuario
Relaxation is guaranteed in this one-of-a-kind glass house nestled in the lush mountains of Altos del María. Surrounded by nature and designed with floor-to-ceiling glass walls on all sides— as if you’re living inside a crystal ball. With no direct neighbors, panoramic forest views, it is perfect for a family getaway, a quiet reset, or an extended stay. The home offers light-filled interiors during the day and unforgettable stargazing nights from the rooftop.
4.76 out of 5 average rating, 170 reviews
Paradise house in a natural setting in Playa Coronado with a pool
Enjoy relaxing days with the whole family or your friends in this peaceful place with lots of nature! The beach is a 5-minute walk away. Many different shops are a 8-minute drive away. Two small shops are also a 5-minute walk away. Everything is taken care of in the house: air conditioning in every room, large 75" TV, washing machine, dryer, hair dryer, towels... everything you need. The pool provides refreshment – a place to feel good!
4.94 out of 5 average rating, 35 reviews
Country House with Pool / Villas del Maria
Relax in this quiet and elegant space. This place is perfect for groups of people, family trips, or a romantic gateway. Located in Sora, 5 minutes from Interamericana, 15 minutes from supermarkets and places to eat in Coronado. Villas del María is a safe and relaxing place to spend time as a family. Enjoy a cozy quiet place with everything you need for your stay. You and your family will love this place!
4.86 out of 5 average rating, 22 reviews
Spectacular Beachfront House
Beautiful house with private beach access right on the property. Relax on the hammocks and be surrounded by nature, with the best ocean view. Only 10 minutes drive from Coronado with all its amenities. There are two wonderful caretakers on the property who are in charge of security, cleaning, and can answer questions and help you with anything you need.
5.0 out of 5 average rating, 41 reviewsPopular amenities for Santa Cruz holiday rentals
Other great holiday rentals in Santa Cruz

20th Flr Beachfront Nueva Gorgona, Panama 2/3 unit
4.89 out of 5 average rating, 71 reviews
Enjoy the view of Mount Picacho
4.89 out of 5 average rating, 85 reviews
Beach house with a pool and a hot tub
4.93 out of 5 average rating, 14 reviews
Beautiful beach villa
4.82 out of 5 average rating, 72 reviews
Your perfect mountain escape
5.0 out of 5 average rating, 15 reviews
Luxury Beachfront Home • Private Pool • Coronado
4.89 out of 5 average rating, 18 reviews
house with 3 bedrooms and a pool
4.9 out of 5 average rating, 10 reviews
Mountain Retreat: Peaceful & Private Escape
4.96 out of 5 average rating, 47 reviewsDestinations to explore
- Panama City Holiday rentals
- Cahuita Holiday rentals
- Quepos Holiday rentals
- Bahía Ballena Holiday rentals
- Coveñas Holiday rentals
- Puerto Viejo de Talamanca Holiday rentals
- Bocas del Toro Province Holiday rentals
- Uvita Holiday rentals
- San Andrés Holiday rentals
- Rio Hato Holiday rentals
- Boquete Holiday rentals
- El Valle Holiday rentals





