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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Home in Costa Esmeralda
4.98 out of 5 average rating, 213 reviews

Beach House-Amazing Pool & Jacuzzi - Pet Friendly

Majestic Sands! Come relax with the whole family at this piece of paradise.located in a private beach community in Costa Esmeralda, San Carlos. Few minutes from the Pan-American highway and a few minutes from other local beaches such as Gorgona, and Coronado. It is a 5-minute walk to our beach, or if you prefer you can go by car. The home includes an amazing saltwater pool and hot tub with hammocks with views of amazing palm trees.Uninterruptible power with Smart Home Energy Management Systems.

Top guest favourite
The exterior of the cabin is depicted, featuring a stone wall and a metal roof. A manicured grass area surrounds the structure, with pine trees in the background against a bright blue sky, creating a serene environment.
Cabin in Chicá
4.94 out of 5 average rating, 303 reviews

Horizonte Cabin by Casa Amaya

Take it easy at this unique and tranquil getaway at Cabaña Horizonte. Casa Amaya is a complex of 6 cabins located in Chicá de Chame, a cool climate between 18 and 24 degrees, where you can connect with nature and relax with your partner, friends or family. https://www.airbnb.com/h/miradorbycasamaya https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya We have an electric generator in case of power outages.

Guest favourite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo
4.97 out of 5 average rating, 31 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Guest favourite
Cabin in Altos del Maria
4.95 out of 5 average rating, 22 reviews

Fobos – Luxury 1-Bed Cabin with Heated Pool

Relax and enjoy Altos del María and its amenities in our brand-new tiny house. With beautiful views, a private jacuzzi, and a modern design, it truly ticks all the boxes. The house is ideal for couples (2 guests) but children are welcome (maximum 2). The kitchen is fully equipped, the bathroom features a modern design, and the bedroom is cozy and comfortable. Located on a shared lot with two others houses, this tiny house is perfect for enjoying a weekend getaway or a longer stay.

Guest favourite
Home in Nueva Gorgona
4.94 out of 5 average rating, 33 reviews

Playa Malibu Beach House.

Wake up to the sound of the waves at this beautiful oceanfront home in Playa Malibu, where the beach is literally your backyard. Step outside and enjoy direct beach access, morning walks on the sand, and unforgettable sunsets over the water. The home features a private pool, BBQ area, and an outdoor dining space perfect for shared meals and long, laid-back evenings. Inside, the house offers a cozy, comfortable, and relaxed vibe, with all the essentials for a stress-free stay.

Top guest favourite
Home in San Carlos
4.91 out of 5 average rating, 163 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Guest favourite
A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.
Home in Chame District
4.93 out of 5 average rating, 57 reviews

Summer House

Bring the whole family to this fantastic place with lots of fun areas. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH has a PH pool and a private pool, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, private hospital (emergency). Close to country activities, beaches, mountains, lake. It has a gazebo with all the amenities. The place is safe and complete.

Guest favourite
A small pool sits within a wooden deck area, surrounded by lush greenery. Steps lead from the deck to the pool, where a gentle waterfall feature adds a soothing element. Lounge chairs are positioned nearby for relaxation in a tranquil setting.
Guest house in Panamá Oeste
4.84 out of 5 average rating, 146 reviews

Mountain cabin with private pool

Enjoy peace and nature in this cozy and equipped cabin, perfect for disconnecting and relaxing. Surrounded by forests and spectacular views, here you can breathe fresh air and gaze at the stars. ✔️ Ideal for couples, families or adventurers. ✔️ Trails, rivers and viewpoints nearby. ✔️ Comfortable and equipped spaces for your comfort. - Sleeps 4 people. - Possibility of having 1 double bed and 2 single beds or 4 single beds. - Discount for two nights or more.

Guest favourite
Home in Altos del Maria
4.91 out of 5 average rating, 23 reviews

4-bed cabin - heated pool - billiards

Escape to a luxury cabin with heated pool, surrounded by nature and tranquillity. The property includes an additional cabin ideal for guests or families. Enjoy spacious terraces, a campfire area, an equipped kitchen, a games room and charming views of the forest and ravine within the property. Perfect for relaxing, unwinding and enjoying a unique experience in a natural setting with all modern amenities. Late check-out is offered as a courtesy on Sundays.

Top guest favourite
Camper van/Motorhome in El Valle de Antón
4.99 out of 5 average rating, 270 reviews

Armadillo Shelter & Garden Valle de Anton

It is a unique and special accommodation that we have designed for you to experience the Anton Valley in a more conscious and natural way. It's a remodeled RV or trailer, to make it cozy>functional and comfortable>tiny house style. The space has a small and complete kitchen, hot water, Wi-Fi, coffee and tea. It is surrounded by a nice garden. With a separate entrance and an area to park the car. Ideal for 1-2 people.

Top guest favourite
A spacious living area is illuminated by natural light streaming through large glass windows. Comfortable seating arrangements are positioned around a circular coffee table, creating an inviting space for relaxation. Scenic mountain views can be seen through the glass, emphasizing the connection with the outdoors.
Cabin in Altos del Maria
4.93 out of 5 average rating, 57 reviews

Blue Sky Lodge; the best view in Altos del María

This luxury mountain cabin offers a modern design, quality finishes, and 180° panoramic views of mountains and sea. It is located in a secure gated community, surrounded by a green garden, with large glass windows that favor connection with nature. The climate is pleasant, with temperatures between 23°C and 28°C. .

Guest favourite
Home in San José
5 out of 5 average rating, 16 reviews

Family Paradise | Pool, Jacuzzi & Garden

Escápate a esta exclusiva villa en Punta Barco, dentro de una urbanización privada. Disfruta piscina y jacuzzi privados, amplias terrazas, un enorme jardin y 4 elegantes recámaras. Perfecta para familias o grupos que buscan lujo, privacidad y cercanía a la playa. El terreno de esta villa es totalmente cercado.

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz