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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A swimming pool is positioned in the foreground, surrounded by lounge chairs and shaded by umbrellas. The house features a terracotta roof and a hammock hangs near the entrance, with lush greenery and a twilight sky providing a serene backdrop.
Home in Playa Coronado
5 out of 5 average rating, 39 reviews

The Dream of Playa Coronado

Whether traveling to Playa Coronado to relax, spend time with family, flee the cold weather or scout your retirement destination, this house is perfectly located in the heart of Playa Coronado and features an airy, tropical ambience, a pool with loungers to soak up the sun, two bohios with dining/lounging areas, hammocks to sway your day away and a BBQ to cook fresh fish bought at the local fish market. The house has a water well so no problems with access to water during the Dry Season.

Guest favourite
A private pool area is featured, surrounded by lush greenery. A patio table with six chairs invites dining outdoors, while a lounge chair with colorful stripes offers a spot for relaxation. A large umbrella provides shade by the shimmering blue water.
Place to stay in San José
4.93 out of 5 average rating, 202 reviews

House in Punta Barco - Pool and Nature

Sun, breeze, nature, and tranquility. House 2 minutes away from the sea. Come and relax with all the amenities. We have: - 1 master bedroom (king size bed) with air conditioning, full bathroom - 1 room with queen bed, bunk bed, A/C, and full bathroom - 1 room with queen bed, bunk bed, air conditioning, and full bathroom - 1 room for service personnel: 1 bunk bed, fan and full bathroom. Private pool with sunbed, a practical bench, and a dining table. Large terrace with 3 hammocks.

Top guest favourite
The exterior of the three-story beach house is showcased, featuring terracotta roofs and lush landscaping. Palm trees and colorful flowers enhance the vibrant surroundings, while the ocean is visible in the background, complementing the peaceful neighborhood setting.
Home in San Carlos
4.94 out of 5 average rating, 149 reviews

OceanView-Rooftop Jacuzzi&Pool | Concierge Service

Unique 3-story beach house – one of a kind. 7 bedrooms, 13 beds, 8.5 baths. hot water. Every room with full bath -AC’s and ceiling fans in all rooms, separate laundry -Rooftop area pool, Jacuzzi, bar, BBQ(charcoal & gas) with amazing ocean view -High ceilings, large open kitchen and living area. -Spacious balcony for dining or relaxing. - 5 min. walk to the beach. -Parking for up to 7 cars - Base rate covers up to 4 guests, with a $40 charge per additional person, per night.

Guest favourite
A dining area is illuminated by natural light streaming through a large window, offering a clear view of the surrounding mountains. A table is set with plates and utensils, creating a space for shared meals while connecting with the scenic landscape.
Cottage in Chame District
4.83 out of 5 average rating, 82 reviews

Cabin with Private Pool in the Mountains

Stay in this country house located 30 minutes from the Pan-American Highway and overlooking the mountains of Panama Oeste and Coclé. This house has a swimming pool, social area, soccer field, and private parking. It can accommodate 10 guests and features basic amenities, a well-equipped kitchen and gas grills, as well as WiFi, TV, and air conditioning in the rooms. It is located a few minutes from trails in the mountains of western Panama and beaches of the Panamanian Pacific.

Guest favourite
Cabin in Altos del Maria
4.9 out of 5 average rating, 29 reviews

Deimos – Modern Mountain Cabin with Heated Pool

Deimos is a one-bedroom cabin featuring a fully equipped kitchen, a modern bathroom, and a living room that opens onto a private terrace with a jacuzzi. The property consists of a total of three houses, and Deimos is located at the highest point, slightly farther from the others, offering added privacy. The tiny home comes fully equipped with everything needed for a weekend getaway or a longer stay, making it the perfect place to relax and enjoy the amenities of Altos del María.

Guest favourite
A cozy cabin is illuminated at night, surrounded by lush greenery and softly glowing lights. A walkway leads to the cabin, enhancing the inviting atmosphere of the outdoor space. Stone features and landscaped areas are visible, creating a serene setting for relaxation.
Cabin in Panamá Oeste
4.82 out of 5 average rating, 374 reviews

Mirador Cabin by Casa Amaya

Casa Amaya is a cabin complex located one hour from the capital city, in Chicá de Chame, with pleasant temperatures between 18 and 24 degrees, where you can get in touch with nature and relax with your partner, friends or family. Other cabins: https://www.airbnb.com/h/lospinosbycasaamaya https://www.airbnb.com/h/buenavistabycasaamaya https://www.airbnb.com/h/panoramabycasaamaya https://www.airbnb.com/h/horizontebycasaamaya We have an electric generator in case of outages.

Guest favourite
Home in Nueva Gorgona
4.94 out of 5 average rating, 33 reviews

Playa Malibu Beach House.

Wake up to the sound of the waves at this beautiful oceanfront home in Playa Malibu, where the beach is literally your backyard. Step outside and enjoy direct beach access, morning walks on the sand, and unforgettable sunsets over the water. The home features a private pool, BBQ area, and an outdoor dining space perfect for shared meals and long, laid-back evenings. Inside, the house offers a cozy, comfortable, and relaxed vibe, with all the essentials for a stress-free stay.

Top guest favourite
Home in San Carlos
4.91 out of 5 average rating, 163 reviews

El Palmar, beach 50 meters away

Listen to the waves from the privacy of our terrace and create unforgettable memories in this unique and family-friendly accommodation just steps from the beach with a private pool. El Palmar is a quiet community with several restaurants available a few steps from the house. The property is fully fenced for the tranquility and safety of children and their pets. In addition, you have wifi, cable TV in both rooms and air conditioning in the dining room and in all the bedrooms

Guest favourite
A modern single-story house is displayed with a large front porch and a carport. The exterior features a mix of light and dark materials, with a neatly landscaped yard and a white picket fence. Clear blue skies and scattered clouds complete the setting.
Home in Chame District
4.93 out of 5 average rating, 57 reviews

Summer House

Bring the whole family to this fantastic place with lots of fun areas. Close to all the amenities of Coronado, a few minutes from beaches, San Carlos lagoon and just an hour and a half from the city. The PH has a PH pool and a private pool, in a quiet and spacious area. You will find 4 supermarkets, pharmacies, private hospital (emergency). Close to country activities, beaches, mountains, lake. It has a gazebo with all the amenities. The place is safe and complete.

Top guest favourite
The modern two-story cabin features large glass windows that offer expansive views of the surrounding greenery. A spacious deck with seating is visible, surrounded by lush vegetation and natural stone pathways leading up to the entrance.
Cabin in Panamá Oeste
4.91 out of 5 average rating, 203 reviews

Altos del María Cabin La Loma de Styria

Relax with the whole family at this peaceful place to stay. It is a fantastic, cool and pleasant place where you can do many ecotourism activities, the best option if you want to have one of the best views you can imagine. Great for couples too. We have 2 bedrooms on the 2nd floor and 2 bathrooms. Multiple places to take beautiful photographs

Top guest favourite
A spacious living area features large windows that provide a view of the ocean. Comfortable seating options include a sectional sofa and armchairs. A round coffee table sits on a textured rug, while ceiling fans circulate air in the bright, airy space.
Apartment in Nueva Gorgona
4.95 out of 5 average rating, 226 reviews

Fabulous Beach Apartment-Ph Royal Palm-Gorgona

FIRST LINE TO THE SEA WITH DIRECT ACCESS TO THE BEACH FROM THE PH POOLS. Fabulous BEACH APARTMENT, Beach Front Unit, comfortable, unique and to relax with the family, it has 4 incredible swimming pools, jacuzzi, sauna, sports courts, board games and access to the beach and restaurant service, coming is not wanting to leave ever

Top guest favourite
An open-plan dining and living area is visible, featuring large glass windows that merge indoor and outdoor environments. A natural wood dining table is arranged for ten, complemented by a plush seating area with a sofa and armchairs. A modern chandelier and a sleek electronic fireplace add warmth to the space.
Cabin in Altos del Maria
4.93 out of 5 average rating, 57 reviews

Blue Sky Lodge; the best view in Altos del María

This luxury mountain cabin offers a modern design, quality finishes, and 180° panoramic views of mountains and sea. It is located in a secure gated community, surrounded by a green garden, with large glass windows that favor connection with nature. The climate is pleasant, with temperatures between 23°C and 28°C. .

Popular amenities for Santa Cruz holiday rentals

  1. Airbnb
  2. Panama
  3. Panamá Oeste
  4. Santa Cruz