
Holiday rentals in Santa María
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Top-rated holiday rentals in Santa María
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Luxury 4BR Villa + Guesthouse & Pool @Buenaventura
Welcome to one of the nicest villas in Buenaventura, Panama's most luxurious beach resort community. This meticulously kept, spacious, 4 bedroom vacation paradise with additional private guest house and pool will make for unforgettable getaways with family and loved ones. Private baths, multiple dining areas, Sonos indoor/outdoor sound system, gorgeous outdoor areas and high end finishes, furnishings, and appliances throughout make every moment spent in Las Portales one to treasure.

Pacific View | Jacuzzi, Pool, Views and Alexa
We are a country house for up to 10 people on a 1,000 m² fenced lot at the highest point of Valle Los Lirios, Las Uvas de San Carlos, maintaining a feeling of isolation. Located in a neighborhood with 24/7 video surveillance and security garage. It offers views of the sea, Valle de Antón and forests. Relax in the jacuzzi with whirlpool and jets or anything in the pool. We have hammocks, barbecue, ping pong table, fire pit and Alexa voice assistant. There is parking for up to 6 cars.

Country House in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Private Beach Studio · Sunset & Nature Views
Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Santiago city, home w/ spacious living & office
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Guacamaya Hill View|3BR Country Home Near Penonomé
We want you to feel truly comfortable and at home. A home away from home. If you’re looking to spend quality time with family or friends, “Mi casa es su casa” at Villas de Santa María is the perfect place to relax, disconnect, and escape the noise of crowded cities. Enjoy our private garden and unwind on the terrace with stunning views of Guacamayas Hill, where you’ll experience peaceful surroundings and beautiful sunsets every afternoon.

Beachfront Loft in Farallón
Wake up to the ocean in this beautiful beachfront loft in Farallón, located in the exclusive Miramar Loft next to the Decameron Hotel. Relax on the balcony with sea views, enjoy the pool, and walk to the beach with private cabanas on the sand. The apartment offers 2 bedrooms, a full kitchen, A/C throughout, and fast Wi-Fi. Just 2 hours from Panama City. Book now and live the beach experience you deserve!

Casamar | Private pool | Garden
Spacious and elegant fully equipped apartment in Casamar. It has 4 bedrooms, 5 bathrooms, each bedroom with its own private bathroom, a guest bathroom, private pool exclusively for our apartment, terrace and garden. Just 70 minutes from Panama City, enjoy this large luxury residential complex facing the Pacific Ocean, where you can spend a few incredible days with your family or friends.

k* Casa Matilde | 3BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 3 bedrooms and 4 beds (1 queen, 1 full & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Sun Cabin at Finca Namuiki by the River
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Panama del Mar
Panama del Mar, nestled in center of Buenaventura, is truly a tropical paradise with a variety of pools, cabanas, pristine beach, restaurants, spas, and everything that makes your vacation relaxing. This spacious home accommodates 12 guests and includes all the conveniences of home. Any further questions can directed to Sandra to 507-6980-1314.

Colonial House in Parita
Discover the charm of Parita from a comfortable and spacious home, perfect for large groups. Located in the picturesque and peaceful town of Parita, in the Herrera Province, just 12 minutes from Chitré, this spacious home is the ideal place to immerse yourself in the history and culture of a historic colonial-era town.
Popular amenities for Santa María holiday rentals
Other great holiday rentals in Santa María

CasAna

Private Oceanfront Villa | Sleeps 14 |Playa Blanca

Stunning loft in Buenaventura Golf&Beach Resort

Puntarena | 2BR | Steps from The Beach Club

Farmhouse

Salamanca Loft

Family home for 8 | 3 bedrooms with air conditioning

Buenaventura home directly on beach, private pool
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