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Holiday rentals in Santa María

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Top-rated holiday rentals in Santa María

Guests agree: these stays are highly rated for location, cleanliness and more.

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Superhost
Cottage in Playa El Jobo
4.76 out of 5 average rating, 120 reviews

Disfruta una Casa de Playa frente al mar, patio

Playa El Jobo is a magical place, special for connecting with nature and resting. It is oceanfront at a height of 9 meters, which allows you to receive the cool sea breeze. The property has a wooden house with a first floor and an upper floor. On the ground floor you will find the kitchen, two full bathrooms, two outdoor showers and a covered space with hammocks. Upstairs there is a large balcony with hammocks, two bedrooms, a living area and two bathrooms. There is good lighting, natural ventilation and A/C

Guest favourite
Two dome structures are positioned on a terrace overlooking a lush green valley. A vibrant sunset casts warm colors across the sky, with scattered clouds creating depth. String lights are visible along the railing, enhancing the natural setting adorned with trees.
Dome in El Valle de Antón
4.87 out of 5 average rating, 101 reviews

5 min from Valle I Domo No. 7-Free coffee

🌄 Dome in El Valle – Nature, peace and incredible views • 🆕 New dome, queen-size bed, Wi-Fi • 🚿 Private en-suite bathroom • 🌬️ Cool mountain climate all year round • 🌿 Surrounded by greenery • 🌄 Stunning views • 🐶 1 small pet • ❄️ Fridge, microwave and coffee maker (no kitchen) • ☕ Welcome courtesy: Small quantities of coffee, sugar and milk for the start of your stay. • 🚗 5 minutes before El Valle (the last two minutes are along a stony track; small cars can pass) • 🕒 3 pm | 🕛 12 pm

Guest favourite
A private pool is surrounded by a smooth concrete deck, with gentle steps leading into the water. The adjacent open-air area features large glass doors that highlight the indoor living space, while the softly lit evening sky adds a serene ambiance.
Home in El Higo
4.96 out of 5 average rating, 26 reviews

CasAna

Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Superhost
A scenic view of rolling hills under a colorful sky at sunset. Shades of orange, pink, and purple blend, creating a vibrant horizon. Lush trees are scattered across the landscape, adding a touch of greenery to the terrain.
Cottage in Olá
4.79 out of 5 average rating, 28 reviews

Country House in Olá, rivers, waterfalls, Los Picachos

Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Guest favourite
A bright bedroom is displayed, featuring a spacious bed covered with a textured white blanket. A television is mounted on the wall opposite the bed. Natural light floods through large windows, accompanied by sheer curtains. A cozy orange chair and potted plant add a touch of warmth.
Tiny home in Playa El Jobo
4.93 out of 5 average rating, 44 reviews

Private Beach Studio · Sunset & Nature Views

Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Guest favourite
Home in Canto del Llano
4.89 out of 5 average rating, 36 reviews

Santiago city, home w/ spacious living & office

Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Top guest favourite
A modern beachfront building rises against a bright blue sky, with large windows reflecting the surroundings. Thatched-roof cabanas are visible on the sandy beach, bordered by lush greenery. The structure stands in a tranquil setting, inviting relaxation and enjoying ocean views.
Loft in Rio Hato
4.98 out of 5 average rating, 58 reviews

Beachfront Loft in Farallón

Wake up to the ocean in this beautiful beachfront loft in Farallón, located in the exclusive Miramar Loft next to the Decameron Hotel. Relax on the balcony with sea views, enjoy the pool, and walk to the beach with private cabanas on the sand. The apartment offers 2 bedrooms, a full kitchen, A/C throughout, and fast Wi-Fi. Just 2 hours from Panama City. Book now and live the beach experience you deserve!

Guest favourite
Farm stay in Santa Fe
4.9 out of 5 average rating, 317 reviews

Sun Cabin at Finca Namuiki by the River

Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

Guest favourite
Cottage in Santa Fe
4.85 out of 5 average rating, 13 reviews

k* Casa Matilde | 2BR Santa Fe Retreat by River

Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Top guest favourite
Home in La Villa de los Santos
4.95 out of 5 average rating, 110 reviews

Spacious house in Villa de los Santos

Comfortable family accommodation in La Villa de Los Santos, with Wi-Fi, A/C, equipped kitchen, patio and parking. Located near supermarkets and plazas. Only 15 minutes from El Rompió and Monagre, 45 minutes from Isla Iguana and 1h 30 minutes from Playa Venao.

Top guest favourite
Home in Rio Hato
4.99 out of 5 average rating, 68 reviews

Vacation Home

Relax with the whole family in this home where the tranquility is breathable. We now have a private beach club for residents, with ample parking, bathrooms, ranches and amenities. It is simply beautiful and relaxing.

Guest favourite
A contemporary cabana is nestled among lush greenery, showcasing a unique stone accent wall. Large windows offer expansive views of the natural surroundings, complemented by a covered terrace that invites outdoor relaxation.
Home in Las Trancas
4.9 out of 5 average rating, 31 reviews

Vergara Cabin Santa Fe

Kick back and relax on this 2 acre ( 1 hectare) private mountain side property, on the Santa Maria River. Equipped with all the amenities you will need to make your stay a home away from home!

Popular amenities for Santa María holiday rentals

  1. Airbnb
  2. Panama
  3. Herrera
  4. Santa María