
Holiday rentals in Santa María
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Top-rated holiday rentals in Santa María
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Spacious Casita with Bamboo View
Walk 20 minutes to the artisan mercado and restaurants on Ruta 71. Cerro Cara Iguana trailhead is walking distance from the casita. High insulated ceilings and 2 ceiling fans for comfort. Private hammock patio for an afternoon nap. Washer/dryer in the casita. Hot water throughout. Kitchen has a 2 burner cooktop, countertop oven, microwave, instant pot, electric skillet, blender and coffee maker. 2 Internet providers and a small workspace available. * No television set * Non smoking property

Paradise from ocean to jungle. Bohío cottage
Welcome to our beach house 850meters to beautiful pacific beach & 3 beach restaurants . Our house is gated and in a safe area .Many areas to visit nearby from surf areas to crater town in the mountains ! Hikes , Canyons , waterfalls ! Coronado is a 35 min drive with all conveniences .New mall is 10 min drive to grocery store , large drugstore. Fish market is 5 min . Seasonal riohato airport 5 min. . Our 1/4 acre property & house is on a country lane with some lovely estates surrounding it.

Country House Like in the City / La Casita
Casa fresca, con árboles y naturaleza. Áreas amplias para descansar. Ubicación céntrica, cerca de malls, restaurantes, estación de buses y ciclovía. Entrada privada, estacionamientos, cocina completa, mobiliario completo, baño, TV HD con cable, AC en recámara, agua caliente y Wi-Fi. ENG, PORT, FRAN and ITA Spoken! Ahora, Chitré, tiene un problema con el agua: no está potable; tenemos 50% de lo habitual, a veces estamos sin agua por algunas horas. Por favor, consulten antes de reserar.

Country House in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

5 min from Valle I Cabaña Vista 1 - Free coffee
🌿 Cabaña Moderna en la Naturaleza – Cerca de El Valle • 🏡 Cabaña moderna rodeada de naturaleza • 📍 A 5 min de Valle de Antón • 🛏️ Espacio tipo estudio: camas, cocina y desayunador integrados • 🍳 Estufa eléctrica (sin horno) y cafetera • 📺 TV • 🌄 Terracita con linda vista • 🐶 Hasta 2 perros pequeños permitidos • 🚗 Pasan todo tipo de auto (ultimos 3 minutos es calle de piedra) • 🫒 Café, azúcar, sal, pimienta, crema y aceite de oliva de cortesía • 🕒 3 pm | 🕛 12 md

Ocean View Marina Stay in Buenaventura | By Alura
Enjoy an exceptional stay in this elegant and modern apartment, located on the top floor in the marina in Buenaventura, Panama’s most exclusive beach resort. It offers panoramic views of the Pacific Ocean and the Marina. The apartment is fully equipped with high-quality furniture and finishes, thoughtfully designed to provide both comfort and style. You’ll also have access to beach clubs, restaurants, and more, for a truly unforgettable resort experience.

Peaceful home w/ spacious living & office area
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Playa Blanca-Spacious waterfront paradise
Conveniently located at 120 km from Panama City in Playa Blanca. Tastefully equipped 88 m2, one bedroom apartment offering more comfort than nearby hotels. Confy bed, lovely terrasse, good bathroom, fully equipped kitchen. The best view to the giant pool. Next to the sport center. Air conditioning, WIFI, cable TV included. Suitable for max. 4 persons. Access to giga salted pool also included it means that you can use the big pool in two parts.

Fenced and Pet-Friendly Cottage in Penonomé
Cozy private cottage, fully fenced — perfect for relaxing, remote work, or traveling with your pet. Enjoy the garden surrounded by greenery, rest in the covered hammocks, or do some birdwatching. Equipped kitchen, air conditioning, high-speed WiFi, and secure on-site parking. Just minutes from the Interamerican Highway, with easy access to cafés, shops, and more. Ideal for a peaceful getaway or productive stay.

Sun Cabin at Finca Namuiki by the River
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.

Little home near to the beach -Las Tablas
10 min drive- Las Tablas Get away from it all when you stay under the stars. A room very close to the sea, with an open kitchen that will allow you to disconnect and enjoy the view and nature in Las Tablas. You can plan to visit nearby beaches or take a walk through Pedasí, 30 minutes from Las Tablas.
Popular amenities for Santa María holiday rentals
Other great holiday rentals in Santa María

Finca los Macanos

Our Happy Place

Stunning loft in Buenaventura Golf&Beach Resort

Beach Apartment - Nikki Beach

Tropical 1BR Apt w/Pool & Beach View

Kincha Casa Cueva (Chitre-Herrera)

Treehouse

Cabin overlooking Picachos Olá. Near rivers and waterfalls
Destinations to explore
- Panama City Holiday rentals
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