
Holiday rentals in Santa María
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Top-rated holiday rentals in Santa María
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Private Pool Oasis in a Tiny Boutique Villa
Eden Ubedi: Your own private sanctuary [WE ARE NOT LOCATED IN VALLE ANTON, it would be a 40-min drive] Enjoy 150m² of exclusive space featuring a private plunge pool, garden, spa bath, and cinema screen. It is one single space: loft-style. Discover a destination beyond the usual tourist spots. Try Panama by staying close to real local communities near the highway Our boutique villa for 2 people ensures privacy with No shops or restaurants nearby, beaches and dining are a 5–10 minute drive

CasAna
Fantástico lugar con espacios abiertos, luz natural y aire puro, 2 habitaciones con baño interno, terraza para recibir el amanecer y el atardecer, piscina privada que hace sentir que vuelas, mientras puedes compartir con amigos y familiares en un área grupal proporcionada por un espacioso deck, disfrutar de tus asados en la terraza y cocina equipada con todo lo que necesitas Ubicada a 10 mtos de Playa La Ermita y 12 mtos de la entrada del Valle, y a un salto del Restaurante Los Camisones.

Country House in Olá, rivers, waterfalls, Los Picachos
Finca La Terapia lives up to its name, it is located among the mountains of the picturesque village of Olá de Penonomé, where you can disconnect from the busy day to day of the city. It has 42 private hectares to explore nature. The Olá district is characterized by having the most beautiful natural landscapes, among which we can mention Los Chorros de Olá, Chorros las Mesitas, Cerros los Picachos, Rio San Antonio, Balneario Brujas, among others, just a few minutes from the property.

Cheerful 3 bedroom countryside Villa with pool.
Forget your worries in this spacious and serene space. This 2 hectares villa includes an 185 square meters house, with 3 air conditioned bedrooms. In addition it includes a swimming pool and 40 square meter ranch. Bedrooms have in total 9 beds, accomodating 12 people. There are 3. 5 bathrooms, internet and hot water. Total perimeter of land is fenced, including an electric gate at the entrance. The price includes the presence of an employee who will support you during your stay.

Casamar | Spacious terrace and garden overlooking the sea
First floor apartment, large terrace and private garden overlooking the ocean, designed with multiple spaces to relax and share. Each bedroom has its own terrace, plus several outdoor environments in the garden. From the property you can directly access one of the pools of the complex and is located a short walk from the sea and the beach club, ideal for enjoying the Casamar experience to the fullest. Resort with water park, swimming pools and beach club with access to the sea.

Private House + Beach 400m + Jacuzzi + BBQ / 10p
Private house in Playa Corona for up to 10 people, just 400 metres from the beach. Ideal for birthdays, family getaways or gatherings with friends. Enjoy a large, spacious hot tub with hydromassage and bubbles, a BBQ area, and a spacious outdoor space to share. A gated property that provides privacy and security during your stay. A 5-minute walk from the beach and close to the river. A comfortable and perfect space for creating unforgettable moments as a group.

Private Beach Studio · Sunset & Nature Views
Designed for comfort, functionality, and a welcoming atmosphere: • Comfortable bed for a truly restful sleep • Air conditioning • Wi-Fi • Kitchen • 2 Bathrooms • Parking Perfect for short stays or longer breaks. Wake up at your leisure, enjoy a relaxing coffee, stroll to the beach, or simply unwind in this space. This place is ideal for: • Romantic getaways • Personal retreats • “Work from the beach” • Escaping the hustle and bustle of the city

Santiago city, home w/ spacious living & office
Spacious and peaceful home in a safe area of Santiago. 4 bedrooms (ideal for families and groups), bright living-dining area and large kitchen to share with family or friends, plus a private office for working comfortably. High-speed Wi-Fi, air conditioning and fans in all rooms, fully equipped kitchen, washer/dryer, and safe for valuables. Self check-in with smart lock, parking for several cars, and a coffee station with board games and karaoke.

Casa Blu Central Chitre| Sleeps 6| Private Parking
Stay in a newly renovated private home in the center of Chitré with free gated parking, a large backyard, fast Wi-Fi, and space for the whole family. Walk to restaurants, supermarkets and the cathedral while enjoying the comfort of an entire home to yourselves. It combines comfort, spaciousness, and natural light in every corner — perfect for families or groups of friends looking for a place that feels just like home.

Beachfront Loft in Farallón
Wake up to the ocean in this beautiful beachfront loft in Farallón, located in the exclusive Miramar Loft next to the Decameron Hotel. Relax on the balcony with sea views, enjoy the pool, and walk to the beach with private cabanas on the sand. The apartment offers 2 bedrooms, a full kitchen, A/C throughout, and fast Wi-Fi. Just 2 hours from Panama City. Book now and live the beach experience you deserve!

Sun Cabin at Finca Namuiki by the River
Spectacular contemporary style villa surrounded by local flowers and woods. The villas design enhances the relationship with the outside environment with panoramic windows which are found in the dining room and kitchen, this offers an awesome view of the mountains and green flora. The villa is located in a organic quiet farm, with abundant vegetation and great presence of birds.

k* Casa Matilde | 2BR Santa Fe Retreat by River
Escape to Casa Matilde, a renovated 100 m² home in Santa Fe de Veraguas. With 2 bedrooms and 3 beds (1 queen & 2 twins), it’s perfect for families or remote workers. Enjoy a bright living room, modern bath with hot water, A/C, and fast Starlink Wi-Fi. Relax by the private creek, explore the river just 200 m away, and take in mountain views—all with total privacy and comfort.
Popular amenities for Santa María holiday rentals
Other great holiday rentals in Santa María

Chitré Oasis: Modern Home with Private Pool & BBQ

Charming house with beach access

Country House with Pool in La Enea de Guararé

Luxury 4BR Villa + Guesthouse & Pool @Buenaventura

Peaceful Garden Home |3BR| Fast WiFi|Near Penonomé

Exclusive cabin with Jacuzzi and unforgettable landscape

Cabin with river view

Cabin overlooking Picachos Olá. Near rivers and waterfalls
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