
Mansion holiday rentals in Santo Domingo
Find and book unique mansions on Airbnb
Top-rated mansion rentals in Santo Domingo
Guests agree: these mansions are highly rated for location, cleanliness and more.

Casa Pantheon Luxury Colonial House
Step back in time in this home first built in 1500 and located in the full heart of Colonial Zone in Santo Domingo, Pedestrian area. The estate, completely renovated in the year 2019, weaves modern luxury into spectacular Spanish colonial architectural elements, showcasing exposed brick, beamed ceiling, archways, courtyard patios, and all other facilities: steam bath, Wi-Fi, 2 smart tv, full Air Cond Totally Private Access to Pool, Jacuzzi and all the spaces of the House. Maid Service INCLUDED

Beautiful Modern Penthouse close to Zona Colonial.
Ideal for groups, Perfectly located in prestigious Gascue next to Palacio Bellas Artes, close to everything. Large 2 floor Penthouse (both floors elevator access). 4 Bedrooms with AC/4.5 Baths, Ocean/City views, 2 floors, 2 rooftop terraces, 2 parking spaces. Walk to El Malecon, Restaurants, Banks, Market and a short 8 minute drive to Zona Colonial, City Center, Plastic Surgery Clinics and attractions. Dedicated work space with internet, 4 smart TVs and much more. Smart lock for easy check-in.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

'Casa de Papel' Luxurious VILLA
Discover the ultimate party getaway at Villa Fiesta Oasis! This luxurious 4-bedroom villa offers everything you need for an unforgettable stay: a sparkling pool, a relaxing jacuzzi, and ample space for entertaining. Located just minutes from the airport, convenience and comfort come together in this stunning retreat. Whether you're hosting a celebration or simply seeking a relaxing escape, House of Cards (Casa de Papel) is your perfect destination. Experience the best of Santo Domingo!

Casa del Orfebre, circa 1525
Welcome to Casa del Orfebre, a jewel from the past, where history comes alive and the charm of the 16th century is breathed in every corner. This antique house, meticulously restored and consolidated, is located in the heart of the Colonial City and is one of the historical buildings certified by the colonial heritage of Santo Domingo, declared a World Heritage Site by UNESCO. 3 rooms have queen beds and 1 room with 2 double beds. So for 10 guests it is a perfect accommodation.

Luxury Rooftop Penthouse|Chef Experience|Sleeps 10
Indulge in a luxury rooftop lifestyle with this stunning penthouse, complete with a private jacuzzi, lounge, and panoramic city views. Elevate your stay with a private chef experience available upon request, creating unforgettable dining moments in total privacy. Ideal for families and groups, this expansive residence comfortably accommodates up to 10 guests while maintaining privacy, elegance, and high standards Note: Private chef service must be arranged in advance.

Luxe 4 Bedrooms, Pool, King Beds
Bring the whole family to this great place with lots of room. This 4 bedroom apartment great for large groups including two king beds. The location of this apartment in one of the most centrally located and exclusive areas in Santo Domingo is reason enough to want to be there, not to mention the exquisite decoration Furthermore the tower with all modern amenities including a pool, gym, and much more making it the perfect choice for you.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Paradise Luxury Penthouse With Private Jacuzzi
Apartamento cómodo y limpio en una area segura. Ubicado en la avenida España. A solo 20 minutos del aeropuerto, 25 minutos de la playa boca chica y 15 mins de la zona colonial. Cuenta con multiple opciones de restaurantes, bars, mixers, supermercado, farmacias, bodegas o colmados y mas a solo minutos. Aire acondicionado en cada dormitorio siempre que haya energía eléctrica, de no haber contamos con abanicos movidos por un inversor.

Spacious house, gated community of Alma Rosa I
Esta casa se encuentra en un residencial cerrado y muy seguro. Està centralmente ubicada; a sólo 20 minutos del aeropuerto de Las Americas y a pocos minutos de los lugares más icónicos del gran Santo Domingo. También puede trasladarse caminando a los restaurantes, supermercado y centros comerciales del area. Ofrecemos check- in temprano y check-out tarde, segun las reservaciones que tengamos pendientes.

Penthouse 5BR | Billar | City View | Terrace Top
Experience a modern 3-level penthouse in the heart of Evaristo Morales. With 5 bedrooms, spacious living areas, a private terrace, and elegant design, it’s ideal for families and groups. Steps from Gold’s Gym, Smart Fit, supermarkets, restaurants, and banks, and minutes from BlueMall, Acropolis, and Ágora Mall. Enjoy comfort, style, and the best location in Santo Domingo.

Villa Francisco RD, (15min Airport) Chef Included.
Do you want to disconnect and enjoy nature? This modern, welcoming apartment is ideal for a weekend with the whole family and will make you feel at home. Enjoy one of the best outdoor spaces by the pool, where you can prepare a delicious barbecue while relaxing and soaking up the sun. 15 minutes from Aeropuerto de las Americas (airport) and 12 minutes from downtown.
Popular amenities for Santo Domingo mansion rentals
Luxury mansion rentals

8-Bedroom Penthouse: Jacuzzi, Pool Table, Terrace

Three Harmony Condos in the Same Building@Pool•Gym

Villa Sabrina

Domus Santa Barbara Pool House Sleeps 12

Villa del Sol

FIXIE Lofts: Elegant Colonial Villa with Pool

✔️ 20-PAX VILLA | POOL | 8-BEDROOM | ZONA COLONIAL

La Casona del Higuero, a paradise in Santo Domingo,
Pet-friendly mansion rentals

villa yaya

Beautiful and comfortable house in the Colonial City

Bonita villa RD

Spacious 4BR pool house with private parking

VillaRosario-Resort-Pool-Wifi-BBQ-NearBeach-Relax

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Luxury Penthouse With Jacuzzi

Res. Obsession
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Beverly Hills Residencíal

6 Bedrooms Vacation Home & Pool (Apartment G-102)

Villa oasis

El Retiro Villa, San Antonio de Guerra.

Villa Luxury: tu paraíso exclusivo

House located in the center of La capital

Comfortable and complete apartment

Luxury 5BR Villa Large Pool Near Airport & Beach
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- Zona Colonial
- Playa Nueva Romana
- Ciudad Juan Bosch
- Playa Hemingway
- Malecón
- Metro Country Club
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- Santo Domingo Country Club
- Teatro Nacional Eduardo Brito
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- Megacentro
- Centro Olímpico Juan Pablo Duarte
- Downtown Center
- Félix Sánchez Olympic Stadium
- Cotubanamá National Park
- Parque Iberoamerica
- Bella Vista Mall
- Dr. Rafael Ma. Moscoso National Botanical Garden
- Cathedral of Santa María la Menor
- Enriquillo Park
- Galería 360
- Agora Mall
- Malecón de San Pedro de Macorís
- Plaza De La Cultura
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