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Holiday rentals in Santo Domingo

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Top-rated holiday rentals in Santo Domingo

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Villa in Playa Venao
5 out of 5 average rating, 8 reviews

Playa Laska – Oceanfront Escape with Infinity Pool

Welcome to Playa Laska, a luxury beachfront villa where tropical elegance meets modern comfort. With three beautifully designed bedrooms, a private infinity pool, and open-air decks surrounded by lush greenery, every corner invites you to unwind, connect, and savor the ocean breeze. Start your mornings with the sound of waves, relax by the pool or stroll along the shore, and let evenings unfold with dining under the stars. Every corner is thoughtfully crafted for a seamless and relaxing stay.

Top guest favourite
An open-concept living area showcases a modern design with a neutral color palette. A plush gray sofa faces a minimalist coffee table, complemented by a decorative plant. Large windows invite natural light, while soft curtains frame the views of the surrounding greenery.
Home in Playa Venao
5 out of 5 average rating, 29 reviews

Nearly Oceanfront: Blue 3 Bedroom Spacious Villa

Villa-33, your exquisite retreat nestled within Blue Playa Venao. Discover a tropical paradise of stunning beaches. Embark on endless adventures just a short walk away. This beautiful Villa offers 3 bedrooms and 3 baths. Two of the bedrooms feature queen beds, while the third bedroom has 2 twin beds, ensuring a restful night's sleep for everyone. The living area, kitchen, and terrace are thoughtfully equipped with everything you need to make yourself at home during your fun family getaway.

Superhost
Cottage in Playa El Jobo
4.76 out of 5 average rating, 120 reviews

Disfruta una Casa de Playa frente al mar, patio

Playa El Jobo, es un lugar mágico, especial para conectar con la naturaleza y descansar. Está frente al mar a 9 metros de altura, lo que permite recibir el fresco de la brisa marina. La finca tiene una casa de madera de PB y un alto. En PB encuentras la cocina, dos baños completos, dos duchas al aire libre y un espacio techado para estar con hamacas. En planta alta hay un gran balcón con hamacas, dos recamaras, un área de estar y dos baños. Hay buena iluminación, ventilación natural y a/c

Top guest favourite
Flat in Las Tablas
5 out of 5 average rating, 12 reviews

Loft Conivan-Las Tablas

Disfruta de Las Tablas como en casa en este amplio y cómodo apartamento completo. Ubicado en un primer piso. Equipado para estancias cortas o largas, con cocina completa, sala acogedora, aire acondicionado y WiFi, ideal para todo tipo de viajeros. A pocos minutos encontrarás playas, restaurantes, supermercados y los principales puntos turísticos del pueblo. Ya sea que vengas por celebración, descanso, o paseo este alojamiento es el punto de partida perfecto para disfrutar Las Tablas.

Guest favourite
A refreshing swimming pool sits in the foreground, complementing the rustic building behind it. Lush greenery and potted plants surround the area, enhancing the natural setting. A shaded patio area with outdoor seating is visible, offering a serene environment for relaxation.
Guest house in La Enea
4.96 out of 5 average rating, 50 reviews

Casa de Campo con Piscina en La Enea de Guararé

Lejos de la urbe capitalina, ven a disfrutar del folklore panameño en un espacio rústico pero acogedor viviendo una experiencia autóctona. Relájate en la piscina ó descansa en una hamaca, respira aire puro, cerca del mar, rodeado de jardines amplios y naturales para un buen paseo. Cerca del Puerto de Guararé donde disfrutarás de los mejores mariscos y bebidas ó disfruta el corazón del mejor evento del folklore resaltando las tradiciones y las mejores polleras panameñas.

Superhost
A sunset view from the property captures golden rays casting soft light over lush greenery and distant hills. The vibrant hues of the sky blend into warm oranges and yellows, illuminating the surroundings, while the ocean can be faintly seen in the distance.
Cottage in Cañas
4.88 out of 5 average rating, 8 reviews

Bella Vista wooden house - near Playa Venao

Unique house in Los Santos! This home is a 60 years old Panamanian wooden house that's been renovated while still keeping its charm. 2 bedroom (main bedroom with king size bed, 2nd bedroom with twin size bed), 1 bathroom, fully equipped kitchen with spacious living and dining room. 1 closed and secure office with A/C with all the equipment needed (office chair, monitor, keypad...) A/C only in office, rest of house with fans! Papaya, our cat, lives in the house!

Top guest favourite
An outdoor space features a small pool surrounded by grass and stone flooring. A covered patio provides sleek bar stools and a grill, complemented by vibrant greenery and tropical plants. Large windows allow natural light to enhance the inviting entrance.
Townhouse in Pedasí
4.99 out of 5 average rating, 72 reviews

Maison de plage à Pedasí

Cette maison toute neuve dans le village de Pedasí vous offre 2 chambres à coucher avec salles de bain et douches privées et un grand salon avec cuisine. En plus il y a une piscine avec espace de bien-être avec grill et un patio couvert derrière, parfait pour se reposer ou bien pour travailler. La maison se trouve à 5 minutes en voiture de différentes plages, entre autre aussi de la playa El Arenal ou vous pouvez prendre le bateau pour aller sur l'Isla Iguana.

Guest favourite
A modern tropical home is set amid lush greenery, featuring an expansive deck that connects to a serene pool. Large glass doors provide a view of the inviting interior and allow natural light to fill the space. Mountains and trees frame the backdrop.
Home in Playa Venao
4.97 out of 5 average rating, 69 reviews

Casa Samambaia - sea view tropical paradise w pool

With a modern tropical design, this home features a cozy living room and a stylish kitchen at the center of the social area. Open the glass doors to immerse yourself in open-concept living, seamlessly blending the indoors with the main terrace and the pool, all oriented towards the ocean view. With two en-suite bedrooms with AC and fans, the house is immersed in nature, green mountains, and a lovely garden, everything 5 minutes from the beach center.

Guest favourite
The modern house is surrounded by lush greenery, featuring a spacious wooden deck with lounge chairs and a private pool. Sliding glass doors enhance the connection with nature, while a covered terrace provides shaded seating areas for relaxation.
Home in Playa Venao
4.91 out of 5 average rating, 68 reviews

Casa Pelicano - Tropical house w pool and seaview

Welcome to Casa Pelicano! Indulge yourself in a retreat with breathtaking views of the ocean and mountains from every corner. Unwind in the private refreshing pool, where the turquoise waters seem to blend seamlessly with the horizon. The stylish interior features open-plan living spaces, perfect for entertaining or relaxing. Whether you're soaking up the sun or gazing at the moonlit ocean under the stars, this home is your ultimate escape.

Guest favourite
Place to stay in Pedasi
4.78 out of 5 average rating, 9 reviews

Una Buena Caminata-Pedasi

Una Buena Caminata is a quiet, spacious villa designed as a retreat base—where days unfold slowly and logistics are handled with care. Set between the town center and Playa El Arenal, the gateway to Isla Iguana, the property offers both connection and seclusion in equal measure. This is not a resort and not a hands-off rental. It is an intentionally curated space for guests who value privacy, ease, and thoughtful living.

Top guest favourite
Villa in El Ciruelo
4.96 out of 5 average rating, 27 reviews

Villa Almanglar - Tropical Home with Pool and View

Escape to 'Al Manglar', where tranquility meets luxury. Enjoy breathtaking views of the mangroves, beach, and ocean from your private infinity pool. This spacious 2-bedroom villa offers king beds, private bathrooms, and a fully equipped kitchen. Perfect for remote work with a dedicated co-working space. Just 7 minutes from Playa Venao, this is your ultimate coastal getaway.

Top guest favourite
The villa is nestled within a lush tropical garden, featuring a private pool with clear, inviting water. Lounge chairs are positioned beside the pool, surrounded by greenery. Large windows illuminate the house, which offers views of the serene outdoor environment.
Villa in Pedasí District
4.87 out of 5 average rating, 186 reviews

Charming beach villa Pedasi, Panama

Villa in the Destiladeros Beach Pedasi (3min walk), private garden and private pool only for the guests of the villa. Very quiet place, secure. For people who are looking for a hidden place, far from the crowd but with all the commodities around (markets in Pedasi village 10min driving, several beaches , little restaurants...). Just to enjoy nature with all the comfort.

Popular amenities for Santo Domingo holiday rentals