
House holiday rentals in Santo Domingo
Find and book unique houses on Airbnb
Top-rated house rentals in Santo Domingo
Guests agree: these houses are highly rated for location, cleanliness and more.

Casa Serena: cozy, modern, spacious and peaceful
Welcome to Casa Serena! A cozy, modern, and spacious house that exudes tranquility... perfect for trips with family or friends seeking a peaceful retreat. The ideal home for those looking to stay in a central area of Santo Domingo while also enjoying the benefits of a low-density residential neighborhood. With easy access, minimal traffic, high safety standards, serene surroundings, friendly neighbors, and a sense of peace, Casa Serena in the La Castellana urbanization is the perfect choice.

Colorful Caribbean house in the Zona Colonial
Enjoy a marvelous stay at this gorgeous, colorful and spacious home at the Zona Colonial. Light, airy rooms and amazing private outdoors create a unique caribbean flair. Relax in the tropical garden...refresh yourself with a dip into the tiny pool…dine under the stars or enjoy the amazing view of the San Francisco monastery ruins from the balcony. The famous Plaza de España is a few steps away and all the historical sites, museums, restaurants, cafés and bars are within easy walking distance.

Beautiful Colonial House with terrace and patio
Beautiful colonial house located in the historic center of Santo Domingo. The house is made up of two studio-apartments, which are rented separately. Each apartment has a bedroom, a bathroom, a living room and a kitchenette to prepare breakfasts and snacks. The two apartments share three areas: a fully equipped kitchen, the patio and the upper terrace. The main historical attractions of the first city of the New World are a five-minute walk from the house.

Stunning villa in Zona Colonial
Casa Republic – Historic Charm, Modern Luxury Tucked away in Santo Domingo’s iconic Zona Colonial, Casa Republic is a 4-suite architectural gem where colonial heritage meets contemporary design. Cool off in your private pool, unwind on the rooftop terrace, or relax in elegant indoor-outdoor spaces crafted for comfort and style. With room for up to 8 guests, this one-of-a-kind home offers a refined retreat in the charm of the old city.

Cozy, central and well-equipped place
We are located in a central and quiet part of the city, with access to 27 de Febrero, Máximo Gómez, and Jhon F. Kennedy avenues. Nearby are the Ibero-American University (Uníbe), Zambil shopping center, Banco Popular Dominicano Tower, as well as pharmacies and health centers. The apartment is located on the first floor, with independent access, parking, and an electric gate. It has a cable system, high-speed WiFi, and an inverter.

Ocean Waves, Boca Chica
Enjoy this charming two-story villa, two bedrooms, two bathrooms, sofa bed, a few meters from the beach, in the best most exclusive area of Boca Chica, just steps from the best restaurants: Boca Marina, St Tropez, Neptuno and Pelicano. Enjoy a cozy atmosphere, a finely furnished atmosphere for you and your family to have a wonderful experience. You'll receive a unique place with personalized service so you never miss a thing.

La Casita de Gazcue Bright C Suite
This simple but charming accommodation offers you a relaxing experience in a privileged location: just a 12-minute walk from the historic Colonial Zone and three blocks from the iconic Malecón, where you can enjoy ocean views, restaurants, and nightlife. Ideal for relaxing without going far, our space combines serenity with quick access to the main tourist, cultural and gastronomic attractions. Your comfort is our priority.

"Peter's Green Villa"
"Si quieres alejarte del ruido de la cuidad y conectarte con la naturaleza, este alojamiento esta pensado para ti, podrás disfrutar con toda tu familia y amigos, de una encantadora villa rodeada de naturaleza y hermosas vistas al horizonte. Un lugar simplemente hermoso donde podrás relajarte y escapar de la rutina diaria." Es para personas aventureras que les gusta la privacidad y tranquilidad de estar alejados de la ciudad!!

Cozy little house in the heart of the Colonial Zone
A cozy 2-bedroom house for 4 people, located in the heart of the Colonial Zone in Santo Domingo, within walking distance of all cultural and tourist attractions. It has 2 comfortable bedrooms and a study with a sofa bed; 2 bathrooms, a nice living room, large dining room, equipped kitchen and a beautiful inner courtyard. Wonderful for vacations and cultural trips, ideal for couples, families, friends, and business travelers.

Charming Colonial House!
Discover this beautiful renovated colonial house with a modern minimalist touch, located 2 minutes from Puerta del Conde and the historic Colonial City of Santo Domingo. Just steps from the Malecón, you'll be in a quiet area but close to restaurants, bars, beauty salons, spas, and supermarkets. Enjoy a comfortable stay in the heart of the city, combining history, modernity, and convenience. Perfect for exploring!

Charming Old City Corner House
This charming 2 bedroom corner house is located in the walled colonial city of Santo Domingo. It’s only a few steps away from historical attractions, museums, restaurants, coffee shops, bars, souvenir shops, bakeries, supermarket and lovely squares. The beautiful covered terrace, overlooking the rooftops of the old town with living area, hammock and BBQ is perfect for a relaxing afternoon or evening.

Your 2BR House + Terrace in the Colonial Zone
Feel the history in this authentic Colonial house from the XVI century with all the modern amenities you will need to make your trip unforgettable. Enjoy a walk to history in the oldest city of America. Visit impressive cultural sites, exquisite restaurants and bars. Have fun in a great night atmosphere. In just minutes you can be in the ocean shore ( malecon ) or in the Colonial promenade.
Popular amenities for house rentals in Santo Domingo
House rentals with a pool

Cheerful 4 bedroom home with pool and parking

Residential apartment in Boca Chica

Exclusive Townhouse, Boca Chica

Experience Ultimate Comfort | 4BR Home

Private Pool, Fast Wi-Fi, A/C, Near Zona Colonial

Casa Aló:Private house with jacuzzi in the Capital

Hm Tropical Villa-Luxury

Huge house with a pool
Weekly house rentals

Private Jacuzzi Apartment | Central Location

Comfortable house in Sto Dgo Este

Luxury house in the East Zone

Cozy Village in Bocachica beach.

“Your home away from home”

Modern House with Terrace

Zona Colonial Large Room, Private Bath & Entrance

Beautiful cozy room
Private house rentals

House for groups with a pool SDE

Large Colonial House • Central • Spacious • Comfortable • Safe

D4FREEE+ComfortBed..

Family Villa in Boca Chica

Winner Village

BRAND NEW 1Bdr Apt in the Heart of SDQ!

Luxurious townhouse in Boca Chica

House in Santo Domingo
Destinations to explore
- Rentals with outdoor seating Santo Domingo
- Rentals with beach access Santo Domingo
- Private suite rentals Santo Domingo
- Smoking-friendly rentals Santo Domingo
- Ski-in/ski-out rentals Santo Domingo
- Serviced apartment rentals Santo Domingo
- Holiday home rentals Santo Domingo
- Rentals with a cinema Santo Domingo
- Villa rentals Santo Domingo
- Rentals with an accessible-height bed Santo Domingo
- Rentals with a firepit Santo Domingo
- Guest house rentals Santo Domingo
- Townhouse rentals Santo Domingo
- Waterfront rentals Santo Domingo
- Farm stay rentals Santo Domingo
- Aparthotel rentals Santo Domingo
- Beachfront rentals Santo Domingo
- Rentals with a sauna Santo Domingo
- Bed and breakfasts Santo Domingo
- Rentals with breakfast Santo Domingo
- Rentals with a washing machine and dryer Santo Domingo
- Hotel rooms Santo Domingo
- Rentals with a patio Santo Domingo
- Loft rentals Santo Domingo
- Pet-friendly rentals Santo Domingo
- Flat rentals Santo Domingo
- Rentals with pools Santo Domingo
- Tiny house rentals Santo Domingo
- Fitness-friendly rentals Santo Domingo
- Family-friendly rentals Santo Domingo
- Cottage rentals Santo Domingo
- Apartment rentals Santo Domingo
- Boutique hotels Santo Domingo
- Rentals with a fireplace Santo Domingo
- Rentals with an EV charger Santo Domingo
- Rentals with lake access Santo Domingo
- Cabin rentals Santo Domingo
- Rentals with a hot tub Santo Domingo
- House rentals Dominican Republic
- Things to do Santo Domingo
- Entertainment Santo Domingo
- Food and drink Santo Domingo
- Things to do Dominican Republic
- Entertainment Dominican Republic
- Sports activities Dominican Republic
- Food and drink Dominican Republic
- Sightseeing Dominican Republic
- Art and culture Dominican Republic
- Nature and outdoors Dominican Republic
- Tours Dominican Republic




