
Pet-friendly holiday rentals in Seneca
Find and book unique pet-friendly homes on Airbnb
Top-rated pet-friendly home rentals in Seneca
Guests agree: these pet-friendly homes are highly rated for location, cleanliness and more.

Waterfront cottage w/deep dock 17 miles to Clemson
Welcome to the Queen of Harts, our 2BR/1BA, waterfront cottage on Lake Hartwell w/private, deep water dock. The house is located on a quite street 25 min to Clemson. Interior has been remodeled including farmhouse kitchen sink, butcher block countertops, dishwasher, large bathroom, washer/dryer, and new furnishings. Enjoy beautiful sunsets on the dock or explore the cove on stand-up paddle boards included with rental. Other amenities include wi-fi, 55" Smart TV, charcoal grill, and fire pit.

The Cashiers Cabin
Remotely located 30 minutes from Cashiers, NC and 45 minutes from Highlands, NC. This is the perfect place to relax, disconnect & immerse yourself into nature. From the cabin take a short hike to the national forest, hiking trails, waterfalls, and the Chattooga River. You can park at the cabin and enjoy nature without driving to other locations. Pets are welcome (fee per stay). If your looking for a peaceful , REMOTE get away this is for you. AWD OR 4WD is needed to park near the house.

Basement apartment in Pendleton w/ sep. entrance
This is a basement apartment in my personal home with its own separate entrance, bathroom, and kitchen. Parking is on the street in front of the house and there’s a concrete walkway that takes you down to the entrance. It’s a studio style apartment with your own thermostat, a king bed, ceiling fans, over 500 sqft, and a fenced backyard for your pup if you bring one. Minutes from Clemson University, T ED Garrison Arena, I85, and 40 min from downtown Greenville. Hulu Live is provided on the tv

Clemson Mom Apartment
Roomy 1 bedroom, 1 bath apartment in Seneca, SC. Approximately 2.5 miles from Wal-Mart and 2 miles from Waffle House. 9 miles from Clemson football stadium. Excellent location with a short drive to restaurants, shopping, 3 24-hour gyms, and grocery stores. Located in a quiet subdivision with minimal traffic. This is the perfect spot, close to Seneca, but away from highly trafficked areas. Great for a working adult and quiet enough during the day for someone working third shift to sleep.

33 Ft Camper perfect for a layover/getaway
Close to Clemson, I- 85, Lake Hartwell, and Anderson. My 2023 Wildwood 28vbxl CAMPER sits in my driveway which is also home to Freedom Fences, a non profit animal rescue. This is a working farm so people are always milling around. Well behaved, housetrained animals allowed but must be crated if left alone. Great spot for Clemson football. 25 minutes to Greenville. 10 minutes from downtown Anderson. Less than 7 miles to Garrison arena. NO Smoking! If you are high maintenance, don't book!

Comfort & Convenience Close to Campus
The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

Magical Historic Cabin | Outdoor Tub
Heady Mountain Cabin, a historic 1890 retreat beside the Nantahala National Forest and our horse pasture. Curated for a dreamy full-service stay with rustic charm, exquisite comfort, and space for romance and reflection. Breathe fresh air, take a bath in the outdoor tub, play a record, gather by the firepit. Slow down and reconnect—with yourself, each other, and nature. Always fresh coffee and a welcome drink. Ideal for a solo retreat, romantic getaway, or a small family.

Cozy Rustic Lakefront Cabin
“on the edge” is a small, cozy, rustic, lakefront cabin with easy walk to a private dock on Lake Hartwell. Great for fishing and swimming. Public boat ramp 2 miles. Living/dining area, two bedrooms. Relax on the large porch with swing and rocking chairs or enjoy fire pit area. No kitchen but includes microwave, full fridge, toaster, Keurig, coffee maker and gas grill. Perfect getaway but also near charming downtown Toccoa, Toccoa Falls, Currahee Mountain, hiking…..

Cozy 3 Br Family Home • 5 min to Clemson Campus
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Rock wood Turtle
The RV is on a 2 acre lot with access to Lake Hartwell. There are trails nearby with many different exploring options in the area. You may interact with me by cell phone or online. I can show you how to operate the propane stove and lights and answer any other questions you might have. The rv shares the same drive way with the green house. I also have kayaks available to rent, so ask me about pricing.

Lakeside Cabin ❤ Seneca Treehouse Project
Visit a cozy lakeside cabin at the Seneca Treehouse Project. It is a 550-square-foot handcrafted studio apartment with a king bed, futon, and blowup twin. Check out our garden & food forest across the street from the cabin. Take a picnic and enjoy the lake. Our goal is to provide a relaxing, inspiring, and educational experience. We encourage questions, there are some unique features on this property.

Cozy Pendleton Cottage ~ Minutes to Clemson
For your next getaway, escape to our Pendleton Cottage. Located just 9 miles from Clemson's Memorial Stadium and only 6 miles to Garrison Arena, you will find everything you need in our home away from home, including a full kitchen, a living room with a 65" TV, 3 bedrooms, each with its own 43" TV, 2 bathrooms, a huge fully fenced back yard, a full laundry room and so much more.
Popular amenities for Seneca pet-friendly home rentals
Pet-friendly house rentals

Comfy, cozy duplex apt in old home downtown Easley

Sweet and Cozy Home for Rent

New! Charming 4/2.5 Modern Home in Clemson, SC

Lake Escape

No cleaning fee farmhouse lake keowee near Clemson

Cozy Modern Home Close Clemson

New! Peaceful Lake Keowee Home ~ Near Clemson

Lakeside Living: Private Dock + 4 Kayaks to Use
Pet-friendly home rentals with a pool

Condo at Lake Keowee

Lakeside Family & Dog Retreat Awaits! DWC

Pete's Place

Golden T's|Dog Friendly| Walk to Pool|Lake Access

Keowee Lakeside with pool for 16

Lake Keowee Loft Cabin + Walkable Dock Access

Winter fun-Ice skating rink minutes away!

Renfrow's Retreat
Private, pet-friendly home rentals

900' of lake front property - 20 min from Clemson

"A Crossvine Cottage

Log Cabin, Table Rock Views, Pet Friendly

Modern home near Clemson, Keowee

Cozy Clemson Lake Hartwell Getaway with Dock

Residences on Main Issqueena Suite

Lion Container Cabin A – Walterfalls, Upstate SC

Keowee Waterfront Lakeside Retreat -Keowee Cottage
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sep | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £86 | £63 | £65 | £91 | £117 | £111 | £115 | £136 | £152 | £74 | £114 | £88 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
Quick stats about holiday rentals that are pet-friendly in Seneca

Total holiday rentals
Explore 20 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at £37 per night before taxes and fees

Verified guest reviews
Over 1,400 verified reviews to help you choose

Family-friendly holiday rentals
10 properties offer extra space & child-friendly amenities

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
20 of Seneca holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests – averaging 4.9 out of 5!
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- Black Rock Mountain State Park
- Gorges State Park
- Tugaloo State Park
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- Mountaintop Golf & Lake Club
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