House holiday rentals in Seneca
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Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for house rentals in Seneca
House rentals with a pool
Home in West Union
4.95 out of 5 average rating, 137 reviewsSunsets and Siestas -Lake Keowee home near Clemson
8–15 Mar
Home in Greenville
5.0 out of 5 average rating, 106 reviewsPalmetto Escape - Pool- Firepit- 6.6 mi DTWN GVL
27 Dec – 3 Jan
Home in Greenville
4.92 out of 5 average rating, 107 reviewsSouthern Bungalow with Stock Tank Pool + Firepit
3–10 Sept
Home in Greenville
4.88 out of 5 average rating, 116 reviewsSaluda Splash Home
3–10 Sept
Home in Westminster
5.0 out of 5 average rating, 19 reviewsThe Hilltop Hideaway at Lake Hartwell
9–16 Dec
Home in Westminster
4.99 out of 5 average rating, 76 reviewsDream Weaver Lakefront• jacuzzi• dog friendly home
13–20 Mar
Home in Seneca
5.0 out of 5 average rating, 11 reviewsKeowee Lakeside with pool for 16
30 Oct – 6 Nov
Home in Salem
5.0 out of 5 average rating, 9 reviewsNewly Updated | Lake Keowee | Pool | Amenities
14–21 Jan
Weekly house rentals
Home in Anderson
4.95 out of 5 average rating, 143 reviewsLake Hartwell House - Cozy and Close to Clemson!
17–24 Feb
Home in Seneca
4.85 out of 5 average rating, 174 reviewsCozy Lake House 5 miles from Clemson w Dock
10–17 Jul
Home in Seneca
4.97 out of 5 average rating, 120 reviewsLake Hartwell house w/ dock 2 miles from Clemson.
16–23 Feb
Home in Pendleton
4.99 out of 5 average rating, 130 reviews3 BR/2BA Cottage in Pendleton - 9 Miles to Clemson
13–20 Jul
Home in Seneca
4.92 out of 5 average rating, 37 reviewsSouth Cove Bungalow Lake Keowee
8–15 Feb
Home in Seneca
5.0 out of 5 average rating, 46 reviewsModern & Cozy Cottage-12 min. from Clemson Uni.
4–11 Aug
Home in Westminster
4.94 out of 5 average rating, 16 reviewsMountain Road Cottage
26 Jul – 2 Aug
Home in Westminster
4.92 out of 5 average rating, 88 reviewsShady Rest
23–30 Aug
Private house rentals
Home in Seneca
5.0 out of 5 average rating, 55 reviewsLake Hartwell Dock, Lakefront, Kayaks, Clemson 4BR
5–12 Dec
Home in Tamassee
5.0 out of 5 average rating, 24 reviewsWhitewater Lake Front Cottage
27 Oct – 3 Nov
Home in Seneca
4.92 out of 5 average rating, 72 reviewsCharming Secluded Lake House Convenient to Clemson
22–29 Oct
Home in Anderson
5.0 out of 5 average rating, 66 reviewsLakefront dock *Hot tub* Anderson Clemson King bed
7–14 Jan
Home in West Union
4.89 out of 5 average rating, 66 reviewsSherwood Forest
2–9 Jan
Home in Seneca
4.96 out of 5 average rating, 54 reviewsTee House... waterfront on beautiful Lake Keowee
25 Oct – 1 Nov
Home in Clemson
5.0 out of 5 average rating, 19 reviewsVaulted Ceilings & Accent Windows--1 mile from CU
16–23 May
Home in Walhalla
4.91 out of 5 average rating, 43 reviewsThe Yellow Quilt in Walhalla
22–29 Jul
Quick stats about house rentals in Seneca
Total rentals
30 properties
Rentals with dedicated workspaces
10 properties have a dedicated workspace
Pet-friendly rentals
10 properties allow pets
Family-friendly rentals
30 properties are a good fit for families
Total number of reviews
1.3K reviews
Nightly prices starting at
£32 before taxes and fees
Destinations to explore
- Gatlinburg Holiday rentals
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- Monthly Rentals Seneca
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