
House holiday rentals in Seneca
Find and book unique houses on Airbnb
Quick stats about house rentals in Seneca

Total holiday rentals
Explore 40 holiday rentals in Seneca

Nightly prices starting at
Seneca holiday rentals start at £37 per night before taxes and fees

Verified guest reviews
Over 1,880 verified reviews to help you choose

Family-friendly holiday rentals
30 properties offer extra space & child-friendly amenities

Pet-friendly holiday rentals
Find 10 rentals that welcome pets

Rentals with dedicated workspaces
10 properties have a dedicated workspace

Wifi availability
40 of Seneca holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Seneca rentals

4.9 Average rating
Seneca stays are highly rated by guests – averaging 4.9 out of 5!
Top-rated house rentals in Seneca
Guests agree: these houses are highly rated for location, cleanliness and more.

Lake Hartwell house w/ dock 2 miles from Clemson.
This is a simple, comfortable, recently renovated (2019) home for Clemson fans and lake vacationers. Decor is vintage/antique. It is 3 1/2 miles to stadium entrance. We have a deep water cove with fire ring, decks, dock, and stairs to gangway, parking for 6 cars, woods and lake on 3 sides, a variety of restaurants nearby. Clemson Marina is 1 cove away. Clemson golf course is across the lake. We are PET FRIENDLY with a max of 2 dogs. There is a $75 pet fee. Read the house rules concerning pets.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Hidden Lake Sanctuary
Recently remodeled and boasting 3000 sq ft, this home offers comfort and serenity. Tucked away in a peaceful cove feeding into Lake Keowee, it’s the perfect escape for nature lovers-especially kayakers. The property comes fully equipped with kayaks and paddle boards. Please note: Access to the dock involves a very steep descent, and the return hike can be challenging—best suited for active guests. Unwind in the private hot tub on the deck or gather around the cozy fire pit.

Singing Pines Cottage
Right among the pines of South Carolina you will find our cottage. It's 5 minutes from the Historic Ram Cat Alley with Live Outdoor music every Thursday Night (Apr.-Oct.), Shopping, Boutiques, Restaurants, Breweries, and Coffee Shops. It's only 12 minutes from Clemson University, and a short drive to Lake Keowee, Lake Jocassee, and Lake Hartwell. This area is home to numerous Waterfalls, Hiking Trails, and good southern barbecue. We do not host work crews.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Shady Rest
As you enter the screened in front porch you will instantly relax, experience a peaceful and quiet tree lined front yard. The house has plenty of shade and old oaks, built in 1935 has the charm of visiting great grandmother’s farm house without the wallpaper. Large side deck with grill, hot tub and plenty of shaded sitting. Side yard has a fire pit for evening campfires and roasting marshmallows. The house has an open floor plan.

Getaway on Lake Hartwell: Pontoon Rental, Clemson
Our 3 bedroom house is located on Lake Hartwell and is just a 15 min drive to Clemson University. You can enjoy access to the dock and beach which are a quick golf cart ride away. We have paddle boards on the dock and kayaks, coolers, bagged ice, fishing poles etc upon request. Off the back of the detached garage there’s a furnished screened-in deck with a grill that overlooks the end of the cove and fire pit below.

The Carriage House at South Townville
Stay in a charming loft-style carriage house in historic downtown Seneca. This two-bedroom space comfortably sleeps 4 and features a full kitchen, private bathroom, and convenient washer/dryer combo. Enjoy walkable access to local shops, restaurants, and coffee spots, or take a short drive to Lake Keowee for boating and views, or visit Clemson University for games and campus events. Perfect for a relaxing getaway.

5 Min to Clemson | Large Driveway & Self Check-In
Welcome to your Cozy Family Home! Escape to this charming 3-bedroom, 2-bathroom home, just a short 3-mile drive from the iconic Clemson Memorial Stadium. Whether you're planning a trip to the lake, tailgating for the big game, catching up with friends, or exploring the local hiking trails, this quiet and convenient home is your ideal base. Can't wait for you to enjoy Clemson, SC. Go Tigers! Pet Fee of $100.

Waterfall Cove - East
Enjoy 1,400 sq ft with a magnificent view of a 25 foot natural waterfall. Secluded, yet only 10 minutes from SC I-85 (Exit 2 and 4) at this unique and tranquil getaway in a cove on Lake Hartwell. Private entrance from deck, full kitchen, dining area, bedroom with new queen bed, bathroom, living room (queen pull-out bed with memory foam). Two TVs,high-speed fiber optic Internet. Sleeps four.

The House on Oak Grove
Enjoy your time spent in this spacious and peaceful pet friendly space. Nicely appointed with everything you need for a short or long term stay. Ten easy miles to Clemson and 3 miles to SWU. Besides the open living space the house has a screened porch and accomodates 4 with 2 bedroom & 2 adjoining baths. The home includes washer & dryer, coffee bar, granite countertops, and microwave.
Popular amenities for house rentals in Seneca
House rentals with a pool

Lakeside Retreat • Pet friendly • Fire Pit

Keowee Key Luxury Condo - Stunning Views!

Lakeside Retreat - 4BR/4BA Home

Pete's Place

See you soon Keowee Kustom!*NO Dock!

Golf view, lake access, 3 pools!

New Construction w/ Pool!

Pool • Hot Tub | Game Room • Fire Pit | Sleeps 14
Weekly house rentals

Sweet Tea Retreats

Modern Home Near Keowee, Clemson, Walhalla

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Lakefront Home w/Deep Water Dock 20 min to Clemson

Mountain Road Cottage

The Landing Spot

New! Charming 4/2.5 Modern Home in Clemson, SC

Valhalla: Cliff-Edge Suite · Forest Views · Tub
Private house rentals

Pet-Friendly 5BR Getaway near Lake Keowee

The Black Brick

Lakefront+Near Clemson+Dock+Kayaks+Putting Green

Deep-Water Keowee Lakefront, Dock, Deck, Kayaks

The Midpoint Manor

Anchor Point, Lake Retreat - Clemson, 2-story dock

No cleaning fee farmhouse lake keowee near Clemson

Cozy Modern Home Close Clemson
When is the best time to visit Seneca?
| Month | Jan | Feb | Mar | Apr | May | Jun | Jul | Aug | Sept | Oct | Nov | Dec |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Avg. price | £127 | £149 | £141 | £113 | £144 | £124 | £122 | £175 | £162 | £145 | £173 | £134 |
| Avg. temp | 6°C | 8°C | 12°C | 16°C | 21°C | 25°C | 27°C | 26°C | 23°C | 17°C | 11°C | 7°C |
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- Clemson University
- Black Rock Mountain State Park
- Table Rock State Park
- Gorges State Park
- Tallulah Gorge State Park
- Helen Tubing & Waterpark
- Devils Fork State Park
- Bell Mountain
- DuPont State Forest
- Unicoi State Park and Lodge
- Bon Secours Wellness Arena
- Chattooga Belle Farm
- Ski Sapphire Valley
- Jump Off Rock
- Fred W Symmes Chapel
- Looking Glass Falls
- Dillard House Restaurant
- Fluor Field at the West End
- Jones Gap State Park
- Anna Ruby Falls
- Peace Center
- Falls Park On The Reedy
- Carl Sandburg Home National Historic Site
- Dry Falls





