
Guest house holiday rentals in Greenville County
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Greenville County
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Greenville County
Family-friendly guest house rentals

Travelers Rest Country Retreat Two miles to NGU
I can't say anything negative about Cliff and Mary's place. It is a gem. You watch horses graze on one side of the house and overlook a pond on the other side. Cliff and Mary are very responsive and go out of their way anticipating their guests needs, stocking the kitchen and fridge with snacks, coffee, cream, and other goodies. Any questions we had about the area were answered immediately. They are pleasant people that I would be glad to call new friends!

La Bella Farm
Jessica and her husband were very welcoming and we defiantly enjoyed our stay!

Holly Hideaway! 10 Highway miles to Clemson U!
Our stay at Jen's place was under special circumstances and to say that Jen was simply accommodating, would be a gross understatement!! Her sweet, quiet, and private guest home proved to be a true God send. Jen went above and beyond to make us feel at home and we are forever grateful.

Private Suite in Downtown Simpsonville
This was the perfect place for us to stay while visiting family in the area ! It was exactly as described ,neat and clean and welcoming ! We would love to stay again when in the area. Thank you !

Quiet Guest Apartment in the Woods
Miranda's guest apartment was perfect for a long term stay. It was well equipped, neat, and ideally located with easy proximity to Paris Mountain State Park as well as downtown Greenville. Miranda was a wonderful host and prompt to respond the few times I needed something.

Executive Suite on a farm @GSP Airport
Wonderful place! Nice people

South Oaks Guesthouse
Diane's place was just what we needed for an overnight stay to watch an early bike race the next morning that took place right near by. The room was clean and the coffee cake was delicious, as described in many other reviews. The room was a bit smaller than expected for the price, but it was beautifully decorated and extremely comfortable. We would definitely stay again!
Guest house rentals with a patio

Budget Bliss: Cozy Elegance
Christian was a great host. The guest home was cute and cozy, perfect for just myself on a weekend trip to visit some family. I had a hard time finding the place initially because it was dark, and Christian responded quickly to help me get there! Thanks so much for a great stay!

Chic Studio with Private Deck
Very comfortable and well equipped space. I especially liked having the back porch. Host was very responsive. Definitely would stay here again.

Birdsong Bungalow-This wk ONLY June/July 10% off
Amy thought of everything in making someone comfortable. This was a quiet and very peaceful place to stay. It is on a dirt road, but after a day or so, I realized I didn’t even mind because it was so peaceful when I arrived. This place is spacious, clean, and all the comforts of home. I would love to stay again sometime! Thank you Amy!

Fun, cozy cottage for two w/games, deck in Easley
we found shannon’s place very last minute when my husband had to rush down here to be at his terminally ill mothers side. shannon was sweet, caring, and her home gave my husband comfort when he would come back from the hospital after a very long day. if we have to come back to the area, this is our new spot

Sugar Creek Retreat
I’ve stayed in several Airbnb’s and they were nice, but Kristen’s was the best by far. It was the most comfortable place to stay. She gets 2 thumbs up. If I had more thumbs she would get them too. Thank you for accepting us.

Botanical Cottage ~Great Check in
Mary's cottage is so cute! Definitely a great option for single people trying to take a mini vacation (like myself)!

Tranquil 2BR Guest House on Pond by Furman
Peaceful surroundings with pond and patio. Great location. Close to shopping, swamp rabbit trail, parks, and mountains. Very clean and nicely decorated. Very responsive host. Hope to stay again.

Shou-Sugi-Ban Retreat on the Saluda River
We absolutely loved staying here! It is a cute little spot that’s got a beautiful view of the river and we felt all alone on the property. It is close to downtown Greenville too. Would definitely recommend and want to stay again!
Guest house rentals with a washing machine and dryer

The Spring Valley Retreat
We had a wonderful stay at Daniel's place! We were there for my son's wedding and it was a peaceful place to come back to in our down time. The guest house was one of the most well stocked Airbnbs we have stayed in. They thought of everything. The kitchen had everything we needed! It is also furnished in such a cozy, relaxed way. Made you feel right at home. I accidentally left some jewelry in the Airbnb and Daniel quickly let me know and made arrangements for me to pick it up. They are such kind people! We would most definitely stay again.

Upscale cottage in Downtown Fountain Inn
This was my second visit here and I can’t wait for my third. The location is perfect, close to beautiful downtown Fountain Inn and just a short trip to downtown Greenville. Lisa is also an amazing host. Super responsive and stays ahead of any questions you might have.

Just off Main near Taylors Mill - Clean & Comfy
This place is so clean and well taken care of. The attention to detail is evident. My son and I really appreciated the separate bedrooms and bathrooms. It was wonderful!

Mod studio- loft, outdoor covered space & parking
grate place easy to handle Tiffany grate person 100% satisfied

Adorable renovated private house w/ parking.
Great place to stay!

Nishleigh's Nook - West End Downtown Greenville
We absolutely loved this space ! I am a house cleaner, and it was sooo clean! The bed was extremely comfortable, and the space is used to every degree to make it feel like a luxury space. It was very private, and we liked that. I loved the creamer and coffee provided, especially since we were there just one night. So nice knowing I didn’t have to pack all that. The small makeup remover pouches were precious. My husband is not an avid walker and I am sure you could walk to places, but we decided to take an Uber to the gathering place and it was only a four minute ride! Just perfect 🤩 Will return

Beautiful guest house
Beautiful place. You can tell he put a lot of work into place. Highly recommend staying here if you’re in town.

Entire Cottage w/Hot Tub - Easy Checkout!
Great host, very responsive! good environment and place was clean!
Destinations to explore
- Rentals with a washing machine and dryer Greenville County
- Rentals with lake access Greenville County
- Rentals with outdoor seating Greenville County
- Tiny house rentals Greenville County
- Rentals with an EV charger Greenville County
- Family-friendly rentals Greenville County
- Rentals with breakfast Greenville County
- Rentals with a hot tub Greenville County
- Rentals with a patio Greenville County
- Cabin rentals Greenville County
- Farm stay rentals Greenville County
- Rentals with a kayak Greenville County
- Rentals with a firepit Greenville County
- Apartment rentals Greenville County
- Pet-friendly rentals Greenville County
- Fitness-friendly rentals Greenville County
- House rentals Greenville County
- Private suite rentals Greenville County
- Rentals with a fireplace Greenville County
- Flat rentals Greenville County
- Rentals with pools Greenville County
- Family-friendly rentals Greenville County
- Loft rentals Greenville County
- Rentals with an accessible-height toilet Greenville County
- Guest house rentals South Carolina
- Guest house rentals United States
- Yurt Rentals United States
- Yurt Rentals United Kingdom
- Castle Rentals United States
- Houseboats United States
- Holiday Caravans United Kingdom
- Private Island Rentals United States
- Farm Houses United States
- Farm Cottages United Kingdom
- Cabin Rentals Australia
- Luxury Cabins United Kingdom
- Luxury Cabins United States
- Holiday Chalets United Kingdom
- Cottage Rentals United States
- Holiday Cottages United Kingdom
- Mansion Rentals United States
- Villa Rentals United Kingdom
- Holiday Bungalows United Kingdom
- Bungalow Rentals United States
- Condo Rentals United States
- Holiday Apartments Australia
- Holiday Houses United States
- Holiday Houses United Kingdom
- Private Holiday Rentals United Kingdom
- Big House Rentals United States
- Big Cottages Australia
- Large Villas United Kingdom
- House Rentals with a Pool United States
- Cabin Rentals with a Pool United States
- Villas with a Pool United Kingdom
- Apartments with a Hot Tub United States
- Holiday Cottages with a Hot Tub United Kingdom
- Beach Cabins United States
- Beach Condos United States
- Beachfront Rentals United States
- Beach Houses United Kingdom
- Beach Villas United Kingdom
- Coastal Cottages United Kingdom
- Pet-Friendly Vacation Rentals United States
- Pet-Friendly Beach Rentals United States
- Pet-Friendly Cabin Rentals United States
- Dog-Friendly Cottages United Kingdom
- Luxury Dog-Friendly Cottages United Kingdom
- Blue Ridge Parkway
- Lake Lure Beach and Water Park
- Table Rock State Park
- Gorges State Park
- Mountaintop Golf & Lake Club
- Jump Off Rock
- Ski Sapphire Valley
- The North Carolina Arboretum
- River Arts District
- Old Edwards Club
- Vineyards for Biltmore Winery
- Thomas Wolfe Memorial
- French Broad River Park
- Discovery Island
- Wade Hampton Golf Club
- Haas Family Golf
- Chimney Rock State Park
- Carl Sandburg Home National Historic Site
- Biltmore Forest County Club
- Woolworth Walk
- Victoria Valley Vineyards
- Things to do Greenville County
- Things to do South Carolina
- Food and drink South Carolina
- Nature and outdoors South Carolina
- Tours South Carolina
- Sports activities South Carolina
- Wellness South Carolina
- Entertainment South Carolina
- Art and culture South Carolina
- Sightseeing South Carolina
- Things to do United States
- Sightseeing United States
- Food and drink United States
- Tours United States
- Wellness United States
- Entertainment United States
- Art and culture United States
- Nature and outdoors United States
- Sports activities United States