
Holiday rentals in Mayo Lake
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Top-rated holiday rentals in Mayo Lake
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Mayo Lake Cabin Fun Peaceful Retreat With Firepits
Moonlight Cabin is a modern waterfront home on Mayo Lake. The lake house and nature provides a secluded and peaceful stay while being minutes from shopping, winery, and dining options. This family friendly cabin is both fun and relaxing. Enjoy quiet mornings overlooking the water with a coffee, swim & play in water, spend evenings by the fire pits, and take in the serenity of nature. Indoors, relax with board games, movies, reading, and fast WiFi. Perfect for couples, families, or work escapes.

Private Lakefront Paradise - Paddleboards & Kayaks
*Dogs only allowed with approval from owner. Scroll down to read more.* Beautiful 3 bedroom, 3 bath home on Mayo Lake in Roxboro, NC. Incredible views of the lake. You rarely see anyone on our secluded cove. You can swim, fish, paddleboard, kayak or tie up your boat. House is only 5 minutes from the marina and comes with paddleboards and kayaks and has a fire pit. Large, open kitchen, family room/ entertainment room, ping pong table, and jetted tub. Close to hiking, fine dining, and VIR.

Water Front Lake House!
Waterfront home on MAYO LAKE. 2 Bd, 1.5 bath fully furnished . Wi-fi, Smart TVs, Alexa, frig, stove washer/dryer, microwave. Queen-size bed, sleeper sofa and bunk bed. Wrap around porch w/ rocking chairs, swing and 2 picnic tables. Large yard for playing, just feet away from the water, and fire pit. Firewood not provided. Lots of fishing, single kayak, 2 person kayak, canoe and 2 paddle boats available. PERFECT FOR ANY SEASON LONG OR SHORT STAY. Located on Mayo Lake in Roxboro, NC

Peaceful tiny house retreat on 30 acre farm
This new tiny house is nestled amongst mature hardwood trees on a 30 acre working family farm in Hillsborough. Quiet your mind and restore your body in the luxurious hot tub or warm up by the cozy fire-pit. Under 10 miles to Hillsborough or Durham, and their many restaurants, breweries and shops. Enjoy the privacy of two secluded wooded acres, surrounded by the sights and sounds of our farm, where we are growing fruits, veggies and mushrooms & caring for our animals and pastures.

Mountain cabin feel on Hyco Lake.
Unwind at this hidden jewel tucked in the woods on Hyco Lake. Forget tiny houses, this “Skinny House” boasts two bedrooms, two baths, a spacious open floor plan, cedar ceilings, fully equipped kitchen, gas grill, solo stove, laundry room. Indoor and outdoor living that is large enough for six adults. Floating dock invites you to spend your days on the lake - swimming, fishing, boating, or just soaking in the views. Canoe, Kayaks, Paddle-boards & life vests provided!

Glass House on the Lake
This midcentury modern retreat nestled in a relaxing cove features floor-to-ceiling glass walls allowing the outdoors in, beautiful exposed wood beams, hardwood floors, and a cozy concrete fireplace. Enjoy the screened porch with new comfortable seating, updated kitchen, and stunning lake views. The gentle slope to the private dock passes by numerous resting nooks. Convenient to the Triangle, Triad, and VIR, it’s the perfect getaway blend of relaxation and adventure.

Lakefront Oasis-HotTub | GameRoom | Kayaks | Dock
At Pointe Mayo Lake, discover a serene, rustic retreat by Mayo Lake. Enjoy amenities like kayaks & canoes, private dock, fishing rods, a grill, a hot tub, a game room, and a fire pit. Perfect for avid vacationers, couples, families, groups of professionals, and even your furry friends! We are Pet and Family Friendly! Love what you see but not ready to book? Click the ❤️ "Save" button on the top right to easily find us again and secure your getaway when you're ready!

Sunset Lakefront Glass Retreat, Hot Tub, Kayaks
Just an hour from RTP, this sunset lakefront retreat is designed around the view, with expansive glass walls that bring Hyco Lake right into the living space. Spend the day on the water—launch a kayak, cast a line from the private dock, or relax by the lake—then unwind in the hot tub or around the fire pit as the sky turns gold. Perfect for romantic getaways, girls' weekends, or a peaceful midweek reset. Fast WiFi makes remote work easy, with on-site EV charging.

Long’s Lakehouse
Relax with the whole family at this peaceful waterfront property. It is a 2 bedroom, 2 bathroom house with one king bed, one queen bed, and a pull out sofa! The kitchen is fully stocked with a coffee pot, utensils, pizza pan, crock pot, skillet, pots , pans, baking sheets, toaster, oven and microwave! Bedrooms and living room have smart tvs. WiFi available! Enjoy the kayaks, lots of fishing, grilling, and fire pit! There is something for here for everyone!

Lake Front | Beautiful Views | Perfect Getaway
Come find a place of rest, relaxation and renewal here at Still Waters. A place that has been built by the hands of its owners, bringing peace to everyone that enters the home. This custom built home is situated just on the waters edge, with a dock and canoes available for use. This home is perfect for a couples get away, looking to recharge away from the hustle and bustle of our everyday lives. Roxboro is about 25 minutes away from the home.

Majestic Lakefront Log Cabin in the NC High Plains
Cozy Log Cabin located on Lake Mayo just above Roxboro, North Carolina on Whispering Wolf Ranch. Easy access to a functional floating dock. Great for fishing, swimming, meditating, or to just enjoy nature. Paddle boards and Kayaks can be rented at nearby Mayo Lake Park. Can be used for a private romantic getaway or family retreat. Less than 5 miles from the events held at Lake Mayo Park. PARTIES OR EVENTS ARE NOT ALLOWED!

The Tiny Cabin At Hurdle Mills - Sauna & Hot Tub
Welcome to our cozy Tiny home on 5 acres nestled in the beautiful town of Hurdle Mills, North Carolina. Surrounded by nature, our tiny cabin is the perfect getaway for those looking to unplug and enjoy the quiet of nature. Relax in the hot tub, build a cozy fire at the fire pit, enjoy the sauna and cold plunge with chiller combo to engage in hot-cold therapy and gaze at the stars, or enjoy your coffee in the cozy indoors.
Popular amenities for Mayo Lake holiday rentals
Other great holiday rentals in Mayo Lake

Lake-Front | Hot Tub, Large Dock, Fire-Pit, Deck

Mollie's Lakehouse

Private Lakefront + Hot Tub, Ping Pong, Foosball

Rustic Country Lakefront Retreat with Fire Pit

The Rustic Roost – Peaceful Farmside Cabin

Hyco Horizon, Boat Tie, Calm Cove, Outdoor Vibes

Large Spacious Home: Close to Hyco and Mayo Lake

Kerr Lake Escape | Dock + Beach Access
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- Duke University
- University of North Carolina at Chapel Hill
- Virginia International Raceway
- William B. Umstead State Park
- Crabtree Valley Mall
- Elon University
- Sarah P. Duke Gardens
- Durham Bulls Athletic Park
- Eno River State Park
- American Tobacco Campus
- Frankie's Fun Park
- Duke Chapel
- Durham Farmers' Market
- Carolina Theatre
- Occoneechee Mountain State Natural Area
- Museum of Life and Science
- American Tobacco Trail
- Durham Performing Arts Center
- North Carolina Central University
- The Durham Hotel
- 21c Museum Hotel
- Falls Lake State Recreation Area
- Lake Crabtree County Park
- Shelley Lake Park





