
Places to stay near Museum of Life and Science
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Top-rated holiday rentals near Museum of Life and Science
Guests agree: these stays are highly rated for location, cleanliness and more.

2-BR apt/garden near downtown Durham arts & eats
A private, restful & artful 2-BR apt. hosted by one of fewer-than-20 Airbnb Belo Award winners in the world. 900 sq. ft. complete lower fl. of 1960s brick split-level on unpaved lane near park. Lush garden. Private entry; parking; lvng rm w/fireplace; bthrm/shwr; kitchenette only; generous amenities; wifi; TV. Superhost since 2014; 1,100+ 5-star reviews. 1 mi. DPAC/Durham Bulls; 1.5 mi. Carolina Theatre; 3 mi. Duke U/Med Cntr. No added cleaning fee. The dear furry ones do not enter the apt.

Warm and Welcoming 3-Bedroom Cottage
Welcome to Carolina Cottage, nestled in one of Durham's premier post WWII neighborhoods, and extensively renovated by Designer + Builder Alicia Hylton-Daniel. Your experience will be enhanced by the thoughtfully curated spaces for relaxing, renewing and re-connecting. The home is spacious, with common areas to be shared, inside and out, as well as quiet spaces to read, nap, scroll and stream. You'll enjoy a full chef's kitchen and dining room, along with a sunny porch and shaded patio.

Tiny Farmhouse in the Heart of Durham
Enjoy the tiny experience without sacrificing the relaxations and comforts of home. Unwind in this quaint 1 bedroom 1 bath tiny farmhouse that’s equipped with full-sized appliances and tasteful amenities. The Farmhouse at Scout is nestled in Downtown Durham’s burgeoning Southside neighborhood and is extremely close to the best restaurants, shops, and activities that Durham has to offer. Major attractions: • DPAC: .8 mi • Durham Bulls: .8 mi • Farmer’s Market: 1.2 mi • Duke: 2.9 mi

Luxurious Modernist Tree House
Stunning, private, and truly one-of-a-kind—this unique home is perfect for a vacation, staycation, special occasion, or simply celebrating everyday life. Designed by renowned modernist architect Frank Harmon. The 2,128-square-foot residence sits on 1.3 acres and was crafted with meticulous attention to detail. Inside, you’ll feel nestled among the treetops while remaining conveniently close to restaurants, shopping, downtown Raleigh, WakeMed, UNC, Duke, and Research Triangle Park.

The Japandi Dome
Experience a taste of Japandi in this dome home on our small homestead, and enjoy the mind and body benefits of being closer to nature with the comforts of indoor amenities. This unique space is built with a full skylight to allow you to sleep under the night sky. Complete with heating and A/C for year-round comfort, a full zen-inspired bathroom, and luxury European bedding. Enjoy your meal around a Japanese inspired floor table with straw mats and meditation cushion for seating.

Modern Tiny House Near Duke & Downtown
You’ll feel like you’re getting away from it all in this modern, private tiny house in the trees, even though you’re just minutes from Duke, downtown Durham, shopping, and restaurants. It’s the perfect balance of peaceful retreat and city convenience. The home includes all the essentials — full kitchen, laundry, A/C, and high-speed internet — but many guests find themselves spending most of their time relaxing on the screened-in porch, listening to birds, and recharging.

Midcentury Modern, Near Duke
Enjoy a relaxing stay in mid-century style with modern convenience. Our midcentury modernized all-steel home, manufactured by the Lustron Corporation in the 1940s, is nestled in a quiet residential neighborhood near Duke University and Hospital, the NC School of Science and Math, and Ninth St shops and restaurants. Our house retains all its original built-in steel cabinetry and features period-appropriate furniture handcrafted by the owner.

Rivers Edge Farm Silo Suite
Enjoy the sounds of nature when you stay in this unique place. The Silo Suite tiny home is nestled in a private area by the silo on our horse farm. This location is fully equipped with all the comforts of home. Loads of day hiking opportunities whether your planning a day trip, weekend getaway or week long vacation there is no shortage of things to do and see. Come enjoy our country setting that’s only minutes away from Duke and Downtown.

The Mural Suite, An Artsy One Bedroom in Durham
A mural filled one bedroom suite with a full bath and kitchenette attached to our house with its own separate entrance. Located less than 5 minutes by car to downtown Durham with easy access for those who prefer to travel by bicycle or foot to the Ellerbee Creek trail. Centrally located to Duke University and Duke Medical. Perfect for longer stays for visiting professionals as well as shorter stays to enjoy all Durham has to offer.

The Angier House | Modern Smart Home | 4Car Garage
Urban-modern near downtown living. Newly built and furnished 4 bedroom, 3.5 bath and features 2 owner suites, on first level and second level of the home. The house has a strong presence with minimal styling to create for a nice vibe and good times. Meticulous attention to detail everywhere you look from the chef-inspired kitchen to the two spacious en suite bathrooms.

Pet Friendly | Cozy Cottage in Bull City
In town for work? Fun? Catching a game? This lovely cottage is an 8 minute drive to Main Street, which means it’s convenient to the fun, but peaceful and quiet when you’re ready for the party to stop. Also less than 15 minutes to Duke Hospital, 20 minutes to Chapel Hill, and 30 minutes to Raleigh. We are also dog-friendly with a fenced in back yard!

Eco-Urban Tiny House near Downtown and Duke
Our Tiny House is a haven, a simple retreat from the rush of daily living, and has been mindfully constructed with eco-friendly, recycled, and sustainable materials. Nestled in a corner of our backyard among old oaks and pines, it feels far from Downtown Durham even though you're only 1.5 miles away (walkable on a greenway).
Popular amenities for holiday rentals near Museum of Life and Science
Apartment rentals with wifi

1 BR Condo in Cameron Village *Pet Friendly*

Lake view condo w/office, walk to food/greenway

Downtown "Bull Durham" Condo

Condo @ Historic Duke Tower

Warehouse District Modern Condo w/ Private Garage

Let’s stay on Peace St

Downtown Durham Midcentury Flat

Condo in Village District near NC State & Downtown
Family-friendly house rentals

Modern 3BR Near DT Durham | Screened Porch

Family Visit+Pet+Fenced+DownTown+FibreWiFi.

Chic Craftsman, Walk to Downtown

Downtown Durham Area

Comfy bungalow (2 BR, 1BA) for any travel need

Guest house With Private Gate Near downtown

Perfectly Appointed @ Duke-Blue Devil Living!

Curated & Caffeinated! Gem near Duke & Downtown
Apartment rentals with air conditioning

Garden Oasis in the heart of downtown Durham

Bull City Apts near Downtown / Duke - Trinity 01

Bungalow retreat: spacious, light, easy access!

Downtown Durham Retreat

Heel-O Sunshine

Dollar Avenue Treehouse near Duke

Walk to Duke Campus! 1 Bedroom in Trinity Park!

100 Year-Old Historic Brick 2BR Loft |Large Patio2
Other great holiday rentals near Museum of Life and Science

*Newly Renovated* 1 BR Bungalow near DT Durham

Forest Retreat! Cozy 4Bed/3Ba mins to Duke & DPAC

New Build |Trinity Park | 5 Min to Duke & Hospital

Sleeps 5| Fenced Yard| Dogs OK| Near Duke & DPAC

Luxury Warehouse District Condo

The Little Bull

Bull City Guest Apartment #1 near Duke East Campus

Luxury Hot Tub | 3BR Suites near Duke
Destinations to explore
- Duke University
- PNC Arena
- North Carolina State University
- Raleigh Convention Center
- Raven Rock State Park
- Sarah P. Duke Gardens
- North Carolina Museum of Natural Sciences
- Durham Bulls Athletic Park
- William B. Umstead State Park
- Lake Johnson Park
- North Carolina Museum of Art
- Eno River State Park
- University of North Carolina at Chapel Hill
- American Tobacco Campus
- Frankie's Fun Park
- Crabtree Valley Mall
- International Civil Rights Center & Museum
- Virginia International Raceway
- North Carolina Museum of History
- Durham Farmers' Market
- Carolina Theatre
- Duke Chapel
- Elon University
- Koka Booth Amphitheatre





