Holiday rentals in Mira Mesa

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Top-rated holiday rentals in Mira Mesa

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
The poolside area features a well-maintained saltwater pool reflecting the colors of the sunset. Comfortable seating arrangements, including lounge chairs and a cozy fire pit, are visible. Large umbrellas provide shade, and lush greenery adds to the serene ambiance.
Guest house in Lake Murray
4.97 out of 5 average rating, 154 reviews

Vacation Paradise-Heated Pool+Hot Tub+FirePit+EV

Welcome to your personal resort! This is your private Guest House with a salt & heated pool + hot tub. Located in a very quiet & safe neighborhood in beautiful San Diego. Drive 15 minutes to the beach, downtown, La Jolla, Zoo, stadiums, Sea World, Convention Center + more. Hike next door at Cowell Mountain or Lake Murray. Smart TV, wifi, two zone AC, full kitchen, W/D combo, top quality finishes & furniture. Everything you need for memorable vacation! No smoking or vaping on the property.

Guest favourite
A game room is featured with vibrant LED lighting, showcasing a foosball table, basketball arcade, and pub table. An outdoor space includes a patio with a dining table and sun umbrella, a built-in grill, and a landscaped area with turf and children's play toys.
Home in Mira Mesa
4.93 out of 5 average rating, 108 reviews

Game Room! Patio, Grill, Backyard, Family-Friendly

Make long-lasting memories at this private, yet centrally-located San Diego home! The backyard features a built in grill, turf for lawn games, and children's toys! The interior includes a game room (basketball, ping pong, foosball, arcade game) and plenty of board games. This property is stocked with baby essentials and beach essentials. Also, the entire home utilizes a water filtration and water softener system! The property is professionally cleaned and sanitized for each guest.

Top guest favourite
A private yard is illuminated with string lights, highlighting the artificial grass area. A patio extends from the back of the suite, with a white fence enclosing the space. The contrasting dark sky adds depth to the peaceful outdoor setting.
Guest house in Mira Mesa
4.94 out of 5 average rating, 139 reviews

Family & Fur Baby Friendly Suite

Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Guest favourite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.91 out of 5 average rating, 152 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Guest favourite
A wooden play structure featuring a slide and windows is placed on mulch in the backyard. A green sandbox sits nearby, under a shaded tree. The fenced area provides a safe and inviting space for outdoor play.
Home in Mira Mesa
4.94 out of 5 average rating, 356 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Guest favourite
An open living space features a comfortable sofa facing a mounted television. A stone accent wall complements the modern design. In the background, a fully equipped kitchen and dining area are visible, with natural light streaming through large windows.
Home in Mira Mesa
4.82 out of 5 average rating, 257 reviews

Modern Kitchen Zen Backyard Putting Green with AC

Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Guest favourite
A spacious living room features a high, beamed ceiling and large windows allowing natural light. Comfortable seating includes a blue sofa and two armchairs, arranged around a central coffee table. A stone fireplace and decorative plants add to the inviting ambiance.
Home in Mira Mesa
4.93 out of 5 average rating, 122 reviews

Open Concept modern ranch w/ bounce house included

Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

Top guest favourite
The living room features a spacious layout with vaulted ceilings, two comfortable sofas, and a coffee table. A decorative mirror hangs above a modern fireplace, while a wine and beverage fridge adds convenience. Natural light enters through the window, enhancing the inviting ambiance.
Home in Mira Mesa
4.96 out of 5 average rating, 109 reviews

Bright Cozy 3b/2b with nice backyard & BBQ

Relax and recharge in our cozy, family-friendly single-story home in the quiet neighborhood of Mira Mesa. Just minutes from dining, shopping, and groceries—and a short drive to San Diego’s beaches, hikes, parks, breweries, and top attractions. Enjoy a spacious living area, fully stocked kitchen, dining for 8, plush memory-foam beds, and a private turf backyard with patio seating—perfect for unwinding after a day of exploring.

Guest favourite
Home in San Diego
5 out of 5 average rating, 10 reviews

Bright & Spacious | Modern Getaway

☀️👨‍🍳 Modern and Open space, additional 500 sq ft patio, close to all the best parts of San Diego! 🖥️👨‍🍳 It comes with AC/heat, a 65-inch TV, high-speed internet, Full Kitchen with smart appliances, washer dryer, a full length mirror, a huge closet with hangers 💦⛱️ Modern bathroom with push button rainfall shower, hair dryer, iron, and plenty of towels ✅ EASY, 24/7 self check-in with smart lock!

Guest favourite
A cozy sleeping area features a spacious bed with a blue blanket and decorative pillows. Soft lighting is provided by two bedside lamps on dark wooden nightstands. A bright piece of wall art hangs above the bed, and a clothing rack is positioned nearby.
Home in Mira Mesa
4.88 out of 5 average rating, 104 reviews

Charming & Spotless Studio with Own Entry

Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.

Top guest favourite
Home in Mira Mesa
4.99 out of 5 average rating, 202 reviews

4BR Family Home, Central Location, Bright & Safe

Safe and centrally located, stand-alone, two-story, four bedroom house with two and one half baths, that is all yours! Bright, airy, and comfortable, with all the comforts of home. Fully stocked kitchen. Many amazing restaurant and shopping offerings within the neighborhood, and 90% of all beaches and attractions are located in less than a 30 minute drive. When you’re at our house, you’re at home!

Guest favourite
Guest house in Mira Mesa
4.96 out of 5 average rating, 46 reviews

Studio 2

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 Full bath. Quiet midtown of Mira Mesa central drive in San Diego. Studio fully equip with 1 queen bed, working desk, kitchenette meant for light food warm, full size refrigerator, single sink meant for light cup and dish wash All shops, restaurants, cinema within minus drive about 2 miles away.

Popular amenities for Mira Mesa holiday rentals

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Quick stats about holiday rentals in Mira Mesa

  • Total holiday rentals

    Explore 290 holiday rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa holiday rentals start at £15 per night before taxes and fees

  • Verified guest reviews

    Over 12,420 verified reviews to help you choose

  • Family-friendly holiday rentals

    120 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 60 rentals that welcome pets

  • Holiday rentals with a pool

    70 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wifi availability

    290 of Mira Mesa holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests – averaging 4.8 out of 5!

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