Holiday rentals in Mira Mesa

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Top-rated holiday rentals in Mira Mesa

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Guest suite in Mira Mesa
4.97 out of 5 average rating, 122 reviews

Private Suite w/ full Kitchen, Bath,Washer & Dryer

Newly-built 1 Bed/1 Bath Guest Suite with private entrance, private restroom, new air conditioning unit, new full-size kitchen and new washer/dryer inside the unit. It's a centrally-located place near Qualcomm, Sorrento Valley, UCSD, La Jolla beaches, etc...Easy access to I-15 and 805 freeways. Convenient travel to Legoland, SeaWorld, San Diego Zoo, USS Midway Museum,Balboa Park and many other attractions in San Diego. It offers everything you need for a nice stay. Check out our awesome reviews!

Guest favourite
A cozy bedroom features a spacious bed with white bedding and blue accent pillows. A comfortable chair is positioned beside the bed, and a small desk sits opposite. Natural light fills the room through a window, which has light, partially open curtains.
Guest house in Mira Mesa
4.93 out of 5 average rating, 122 reviews

Private Guesthouse ADU #1 · Mira Mesa · Kit & Bath

Welcome to this cozy retreat in Mira Mesa! This is Unit #1, a fully private guesthouse ADU with its own entrance, a kitchenette, and a private bathroom, ideal for travelers who value privacy and convenience. Driving time to: Downtown - 20 min Sorrento Valley Coaster Station - 10 min Illumina - 7 min Qualcomm offices - 5 min La Jolla/ Del Mar beaches - 17 min Del Mar Fairground - 15 min UCSD campus - 11 min San Diego Zoo/Balboa park - 19 min (Note: Driving times may vary based on traffic.)

Top guest favourite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.92 out of 5 average rating, 143 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Guest favourite
Guest house in Mira Mesa
4.92 out of 5 average rating, 110 reviews

Family, Pet paradise _Sunshine San Diego

Welcome to our cozy San Diego Mira Mesa Guesthouse! This private 600 sqft suite offers comfort and convenience for families, friends, and pets. Enjoy a brand-new sofabed added Sep 13th 2025. For those working during their stay, the suite includes a dedicated remote-friendly workspace with fast WiFi and natural light, ideal for video calls or productivity on the go. With quick access to Freeway 15, you’re just 15–20 minutes from beaches, downtown, and San Diego’s top attractions.

Guest favourite
A light-filled room features a full bed with white linens, complemented by a bedside table with a small decorative plant. A wardrobe provides storage space, while a desk and chair offer additional utility. The window, covered by blinds, allows for natural light to filter in.
Private room in Mira Mesa
4.92 out of 5 average rating, 201 reviews

Room2 with shared bath in Miramesa

译文 Our home is located in the quiet community in Mira mesa. I am Chinese, my husband is American. This is a small room,public one bathroom. Bath supplies complete, provide clean towels. The room is comfortable and simple ,it has a 1.5* 2.0m full bed, as well as big wardrobe, drawer cabinet, chair, desk ,lamp and other living things. Free parking in front of the house! Free wi-fi . For safety purposes, a Blink security camera is installed outside the front door.

Top guest favourite
A spacious bedroom features a black metal bed frame with patterned bedding. A small bedside table is positioned beside the bed. Natural light fills the room through a large window, which is adorned with light-colored curtains that complement the neutral walls.
Guest house in Mira Mesa
4.92 out of 5 average rating, 79 reviews

Gated Detached Large House Convenient/Quiet

The spacious detached casita/guest house comes with private entrance and a backyard. It has a large bedroom, walk-in closet, full bathroom, living dinning, and kitchen. The kitchen has new sink, stove/oven, refrigerators, essential cookware, utensils, and tableware. The house has a queen size bed that can sleep two adults, a brand new sofa sleeper bed and a queen size air mattress for additional guests. Guest may use the new LG washer/dryer combo unit.

Top guest favourite
A single-story ranch home is set amidst a landscaped front yard featuring vibrant green grass and white gravel accents. A large tree provides shade by the entrance, while a well-maintained driveway leads to a garage. Clear skies add to the welcoming exterior ambiance.
Home in Mira Mesa
4.98 out of 5 average rating, 58 reviews

Charming Family 3BR w/ Game Room

Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Home in Mira Mesa
4.94 out of 5 average rating, 34 reviews

2 Bed 1 Bath Entire House

Dear Guest, This is a 1 story house located in the heart of Mira Mesa. It is in a quiet residential neighborhood. Driveway and street parking are available to use. You will have the entire house to yourself. The living room, a full kitchen, a full bathroom with tub, a laundry room and 2 bedrooms. This space is excellent for a small group of friends, or a family to stay while you enjoy your visit to San Diego.

Guest favourite
A spacious living area features high ceilings and natural light flowing through plantation shutters. A comfortable sofa is positioned alongside a coffee table and accent chair. A dining table is set for six, complemented by decorative wall art and a chandelier overhead.
Private room in Rancho Penasquitos
4.95 out of 5 average rating, 231 reviews

Private Room in Upscale House

Desirable quiet neighborhood, luxury accommodations, large gourmet kitchen, indoor laundry, fenced back yard. Close to parks, highways, hiking, stores, restaurants. Upgraded, modern, single-level house; central AC and fan in bedroom. Newer furniture, adjustable bed to raise head and/or feet with memory foam mattress. Large bathroom - dual sinks. Breakfast included. I have another AIRBNB queen bedroom.

Guest favourite
A cozy sleeping area features a spacious bed with a blue blanket and decorative pillows. Soft lighting is provided by two bedside lamps on dark wooden nightstands. A bright piece of wall art hangs above the bed, and a clothing rack is positioned nearby.
Home in Mira Mesa
4.84 out of 5 average rating, 70 reviews

Charming & Spotless Studio with Own Entry

Entire Private Studio Suite. Brand new updated entire suite with 1 Queen Bed & 1 Full bathroom. Ideal for couples, solo adventurers, and business travelers. Just minutes from central of shopping and food like Asian restaurants, markets as well as 24h stores, Edward Cinema, etc... Less than 20 mins to Balboa Park, La Jolla Shores Park, Solana Beach, Moonlight Beach, San Diego Zoo, San Diego Sea World.

Guest favourite
A modern living area features a blue upholstered sofa paired with two wooden armchairs. A wooden coffee table sits in front, complemented by a decorative rug. A plant adds a touch of greenery, while artwork adorns the wall. A dining area is visible in the background.
Home in Mira Mesa
5 out of 5 average rating, 25 reviews

Urban Oasis - Just Remodeled

**Brand New Listing** Located in the heart of Mira Mesa and just minutes from the 15 Freeway, this beautifully remodeled home offers the perfect combination of style, comfort, and convenience. Whether you're visiting for business, pleasure, or a bit of both, you'll love the thoughtful upgrades and luxurious touches throughout. The home offers plenty of parking, in a safe neighborhood.

Home in La Mesa
4.72 out of 5 average rating, 53 reviews

Charming Family-Friendly La Mesa Getaway

Live like a local in this cozy, family-friendly La Mesa home! Features 4 comfy bedrooms, 2 full baths, full kitchen, and spacious living room. Enjoy sunny SoCal weather on the covered patio or backyard with BBQ. Walk to cafes, craft beer spots, and parks — plus quick freeway access to all of San Diego. Includes family essentials like crib, high chair and toys!

Popular amenities for Mira Mesa holiday rentals

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Quick stats about holiday rentals in Mira Mesa

  • Total holiday rentals

    Explore 270 holiday rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa holiday rentals start at £15 per night before taxes and fees

  • Verified guest reviews

    Over 12,970 verified reviews to help you choose

  • Family-friendly holiday rentals

    100 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 50 rentals that welcome pets

  • Holiday rentals with a pool

    60 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wifi availability

    270 of Mira Mesa holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests – averaging 4.8 out of 5!

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