Holiday rentals in Mira Mesa

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Top-rated holiday rentals in Mira Mesa

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A two-story house features a stylish facade with a sloped roof and decorative elements. A garage is visible on the left, with a driveway leading to the entrance. Lush greenery surrounds the home, enhancing the inviting exterior.
Home in Mira Mesa
4.94 out of 5 average rating, 203 reviews

Spacious, Yard+Patio+Beach+Zoo+Legoland

A home great for families. Conveniently 1 mile to the shopping center and popular restaurants. One block walk to a pet friendly park with playground. Just ask me for recommendations for where to go and eat! This is a popular home for families wanting to visit Legoland, Torrey State Beaches, and is only 16 minutes to Balboa Park and the Zoo! We have many outdoor amenities to help you host your group - Games, BBQ, Fire pit, dining table, outdoor sofa, and string lights throughout the backyard!

Top guest favourite
An open living area showcases modern furnishings, including a light gray sectional sofa and a sleek coffee table. A workspace with a desk and chair is positioned near a window, while a bright kitchen area features stylish cabinetry and countertops visible in the background.
Home in Rancho Penasquitos
4.95 out of 5 average rating, 111 reviews

Peaceful in Penasquitos

NO AIRBNB FEES ARE CHARGED TO GUEST. Relax with the friends and family at this peaceful place to stay. Newly remodeled kitchen, bathrooms, appliances. Child friendly. Property is off of 56 Freeway and Rancho Peñasquitos Blvd. Driving Distance: 25 mins from San Diego Convention Center 25 min from San Diego International Airport 30 mins from Legoland (North County) 20 mins from San Diego Safari Park Zoo (North County) 25 mins from San Diego Zoo 25 mins from Mission Bay 25 mins from Downtown

Top guest favourite
A modern living area is shown with a comfortable gray sectional sofa adorned with decorative pillows. A round coffee table is positioned in front, holding a bowl and a stack of magazines. Large windows provide natural light, complemented by a warm floor lamp.
Guest house in Mira Mesa
5 out of 5 average rating, 38 reviews

Bright Modern Family Friendly Guest House

Welcome to our bright and cozy family friendly home located in the neighborhood of Mira Mesa, San Diego. This 3bed/2bath home is perfect for those looking for a peaceful retreat while still being close to the excitement of the city. You'll enjoy the open concept living and dining area that comes complete with a full-size kitchen & all the modern amenities needed for a comfortable stay- high-speed wifi, coffee, TV, & board games and only a short drive to beaches or downtown. 10mins to UCSD

Guest favourite
A game room is featured with vibrant LED lighting, showcasing a foosball table, basketball arcade, and pub table. An outdoor space includes a patio with a dining table and sun umbrella, a built-in grill, and a landscaped area with turf and children's play toys.
Home in Mira Mesa
4.92 out of 5 average rating, 101 reviews

Game Room! Patio, Grill, Backyard, Family-Friendly

Make long-lasting memories at this private, yet centrally-located San Diego home! The backyard features a built in grill, turf for lawn games, and children's toys! The interior includes a game room (basketball, ping pong, foosball, arcade game) and plenty of board games. This property is stocked with baby essentials and beach essentials. Also, the entire home utilizes a water filtration and water softener system! The property is professionally cleaned and sanitized for each guest.

Top guest favourite
A private yard is illuminated with string lights, highlighting the artificial grass area. A patio extends from the back of the suite, with a white fence enclosing the space. The contrasting dark sky adds depth to the peaceful outdoor setting.
Guest house in Mira Mesa
4.93 out of 5 average rating, 131 reviews

Easter Break Special Cozy Stay for Family & Pets

Welcome to our cozy Mira Mesa guesthouse in San Diego! This private 600 sq ft suite is perfect for families, friends, and pet-friendly stays. Enjoy a brand-new sofa bed (Sept 13, 2025) plus recent updates including a side bed, added storage, new wall décor, and curtains (Mar 22, 2026). The space also features a bright workspace with fast WiFi—ideal for remote work. Conveniently located near Freeway 15, you’re just 15–20 minutes from beaches, downtown, and top San Diego attractions.

Guest favourite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.91 out of 5 average rating, 149 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Top guest favourite
A wooden play structure featuring a slide and windows is placed on mulch in the backyard. A green sandbox sits nearby, under a shaded tree. The fenced area provides a safe and inviting space for outdoor play.
Home in Mira Mesa
4.94 out of 5 average rating, 348 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Superhost
An open living space features a comfortable sofa facing a mounted television. A stone accent wall complements the modern design. In the background, a fully equipped kitchen and dining area are visible, with natural light streaming through large windows.
Home in Mira Mesa
4.82 out of 5 average rating, 253 reviews

Modern Kitchen Zen Backyard Putting Green with AC

Our beautiful home is located in the heart of San Diego. From the living room front door you'll see through to the kitchen, family room, and straight into the wide backyard with a putting green. Set up perfectly for family gatherings. Kitchen comes fully equipped. - Thermador stove, down vent hood, microwave, oven, and wide island Backyard perfect for a gathering: Safe and clean for the kids to run around. Has putting green, fire pit, and multiple lounge areas.

Top guest favourite
A single-story ranch home is set amidst a landscaped front yard featuring vibrant green grass and white gravel accents. A large tree provides shade by the entrance, while a well-maintained driveway leads to a garage. Clear skies add to the welcoming exterior ambiance.
Home in Mira Mesa
4.98 out of 5 average rating, 81 reviews

Charming Family 3BR w/ Game Room

Experience San Diego living in this welcoming 3-bed, 2-bath Mira Mesa home. Perfect for families with a fun game room for entertainment and a spacious backyard featuring covered patio seating and grill for outdoor dining. Minutes from scenic hiking trails, family-friendly parks, and beautiful beaches. Easy access to diverse local restaurants. Your ideal Southern California base with space for both lively gatherings and relaxing downtime.

Guest favourite
Home in Mira Mesa
4.93 out of 5 average rating, 116 reviews

Open Concept modern ranch w/ bounce house included

Come and relax at our California ranch style family friendly home which is a 1 story (no stairs) 3 bedroom 2 bath home in Sunny San Diego.. This open concept home has two living rooms and a backyard patio to grill and lots of grass for the kiddos to run around in. This house is centrally located in San Diego and a quick drive to the beach, the San Diego Zoo, local hospitals, Petco Park for padres, Legoland, and downtown San Diego.

Top guest favourite
The living room features a spacious layout with vaulted ceilings, two comfortable sofas, and a coffee table. A decorative mirror hangs above a modern fireplace, while a wine and beverage fridge adds convenience. Natural light enters through the window, enhancing the inviting ambiance.
Home in Mira Mesa
4.96 out of 5 average rating, 109 reviews

Bright Cozy 3b/2b with nice backyard & BBQ

Relax and recharge in our cozy, family-friendly single-story home in the quiet neighborhood of Mira Mesa. Just minutes from dining, shopping, and groceries—and a short drive to San Diego’s beaches, hikes, parks, breweries, and top attractions. Enjoy a spacious living area, fully stocked kitchen, dining for 8, plush memory-foam beds, and a private turf backyard with patio seating—perfect for unwinding after a day of exploring.

Guest favourite
Home in Mira Mesa
5 out of 5 average rating, 10 reviews

Bright & Spacious | Modern Getaway

☀️👨‍🍳 Modern and Open space, additional 500 sq ft patio, close to all the best parts of San Diego! 🖥️👨‍🍳 It comes with AC/heat, a 65-inch TV, high-speed internet, Full Kitchen with smart appliances, washer dryer, a full length mirror, a huge closet with hangers 💦⛱️ Modern bathroom with push button rainfall shower, hair dryer, iron, and plenty of towels ✅ EASY, 24/7 self check-in with smart lock!

Popular amenities for Mira Mesa holiday rentals

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Quick stats about holiday rentals in Mira Mesa

  • Total holiday rentals

    Explore 280 holiday rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa holiday rentals start at £15 per night before taxes and fees

  • Verified guest reviews

    Over 12,920 verified reviews to help you choose

  • Family-friendly holiday rentals

    110 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 60 rentals that welcome pets

  • Holiday rentals with a pool

    60 properties feature pools

  • Rentals with dedicated workspaces

    190 properties have a dedicated workspace

  • Wifi availability

    280 of Mira Mesa holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests – averaging 4.8 out of 5!

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