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Family-friendly holiday rentals in Mira Mesa

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Mira Mesa

Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

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Top guest favourite
A contemporary living area is featured with a sleek sofa positioned against the wall. Two windows allow natural light to fill the space. A television is placed on a low console, accompanied by a small plant and a floor lamp. The entrance is marked by a white door.
Guest suite in Mira Mesa
4.97 out of 5 average rating, 121 reviews

Private Suite w/ full Kitchen, Bath,Washer & Dryer

Newly-built 1 Bed/1 Bath Guest Suite with private entrance, private restroom, new air conditioning unit, new full-size kitchen and new washer/dryer inside the unit. It's a centrally-located place near Qualcomm, Sorrento Valley, UCSD, La Jolla beaches, etc...Easy access to I-15 and 805 freeways. Convenient travel to Legoland, SeaWorld, San Diego Zoo, USS Midway Museum,Balboa Park and many other attractions in San Diego. It offers everything you need for a nice stay. Check out our awesome reviews!

Guest favourite
A spacious bedroom features a king bed dressed with a patterned duvet. A stone fireplace adds warmth, while a dresser and TV are positioned nearby. Natural light filters through large windows, highlighting the vaulted wooden ceiling and creating an inviting atmosphere.
Guest suite in Santee
4.95 out of 5 average rating, 370 reviews

Spacious 1 Bdrm Unit: king bed, fireplace, parking

Come relax in this bright & spacious 1 bedroom detached unit with private entrance. This room has a king bed, fireplace, full bathroom, table & chairs, mini fridge/freezer, microwave, closet ,dresser, Tv and beautiful mountain views. La Jolla Beaches, downtown San Diego, the Zoo, and Sea World are 25 minutes away. Santee Lakes is just a short drive away where you can enjoy fishing, paddle boating, splash park, biking and picnic area. Mission Gorge Trails is also located just 5 minutes away.

Guest favourite
A cozy studio suite features a queen bed with fresh linens and a sleek, dark wood frame. A full-size leather sofa is positioned near a decorative coffee table. Soft lighting illuminates the gray walls, and artwork is displayed above the bed.
Guest house in Rancho Penasquitos
4.92 out of 5 average rating, 111 reviews

❤ Cozy Private Studio w/ WD 2 Minutes from Freeway

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 bath. Ideal for couples, solo adventurers, and business travelers alike. Studio is fully equipped with AC, 1 queen bed, full-size leather sofa, working desk, kitchenette meant for light food warm, mini size refrigerator, single sink meant for light cup and dish wash. All new furniture, comfortable mattress, fresh linen! All shops, restaurants, cinema, hiking trails within minus drive about 1-5 miles away!!!!

Guest favourite
A spacious room is furnished with a plush brown sectional sofa adorned with red accent pillows and an ottoman. A large bed with neutral bedding is positioned nearby, and framed artwork adds subtle elegance to the wall, complemented by soft ceiling lights that enhance the inviting space.
Guest suite in Mira Mesa
4.92 out of 5 average rating, 142 reviews

Stunning Private Entrance 2bd/1ba Suite

Located in the heart of San Diego, guests are a short drive or bus ride to all the local hotspots. Shopping and restaurants are within walking distance. The space itself is large, exquisitely decorated, has a dedicated driveway parking space and its own private entrance in the front of the house. Also available are the washer/dryer for laundry, beach equipment, electric bikes (with signed waiver), cribs/toys/etc. for children. Short drive to SeaWorld, Zoo, Safari Park and beaches.

Guest favourite
A cozy sleeping area features a spacious bed draped in a patterned bedspread. Natural light filters in through a nearby window, illuminating the room. Modern art adorns the wall, adding a touch of character to the minimalist space.
Guest house in Mira Mesa
4.92 out of 5 average rating, 106 reviews

Cozy Family & Pet-Friendly & Remote work

Welcome to our cozy San Diego Mira Mesa Guesthouse! This private 600 sqft suite offers comfort and convenience for families, friends, and pets. Enjoy a brand-new sofabed added Sep 13th 2025. For those working during their stay, the suite includes a dedicated remote-friendly workspace with fast WiFi and natural light, ideal for video calls or productivity on the go. With quick access to Freeway 15, you’re just 15–20 minutes from beaches, downtown, and San Diego’s top attractions.

Top guest favourite
A wooden play structure featuring a slide and windows is placed on mulch in the backyard. A green sandbox sits nearby, under a shaded tree. The fenced area provides a safe and inviting space for outdoor play.
Home in Mira Mesa
4.94 out of 5 average rating, 330 reviews

Contemporary Family-Friendly Home in SD with EV&AC

Welcome to San Diego, the city of sun and fun. This newly-renovated, spacious home has 3 beds and 2 baths with central AC, and is conveniently located in the center of San Diego with easy access to freeways 5, 805 and 15. It's close to many attractions -Legoland, Sea World, San Diego Zoo, Balboa Park, and beautiful beaches. The neighborhood has a variety of restaurants, cafes, movie theater, shopping center, and grocery stores. Just a few minutes from Sorrento Valley and UCSD.

Guest favourite
A compact kitchenette features cream-colored cabinetry complemented by a vibrant blue countertop. Appliances include a microwave and refrigerator, with cooking utensils and dishware neatly arranged on the open shelves above. A flat-screen TV is mounted on the wall, enhancing the functional space.
Guest suite in Lemon Grove
4.87 out of 5 average rating, 245 reviews

GROVE CASITA/ Amiable Room, Private Enrty, Bath

Quaint Guest Space - 2 easy, fast access ways to Freeway - Keypad entry - Parking - AIR CONDITIONING, - Wired internet, Wi-Fi - Laundry - 10 to 15 minutes to downtown San Diego, the Convention Center, Little Italy, and 32nd Naval Base, San Diego Zoo/ Balboa Park, Coronado Island beach - 15 to 20 minutes to Sea World, Tijuana Mexico, La Jolla, Imperial Beach, Ocean Beach - 1.6 miles to Trolley - 0.6 miles to bus Bus lines - Close to Grocery Stores , fast food, and restaurants

Top guest favourite
The living room features a spacious layout with vaulted ceilings, two comfortable sofas, and a coffee table. A decorative mirror hangs above a modern fireplace, while a wine and beverage fridge adds convenience. Natural light enters through the window, enhancing the inviting ambiance.
Home in Mira Mesa
4.96 out of 5 average rating, 104 reviews

Bright Cozy 3b/2b with nice backyard & BBQ

Our family-friendly, single story home is centrally located in a quiet neighborhood of Mira Mesa. Less than 1 mile to restaurants, grocery stores, banks, shopping centers while just a short drive to beaches, hikes, parks, local breweries & San Diego attractions. The entire home offers a spacious living room, a separate fully equipped kitchen and dining up to 8, comfy beddings, memory foam mattresses in all rooms & turf backyard with patio furniture for a comfy, relaxed stay.

Top guest favourite
A comfortable living room features a gray sectional sofa arranged around a coffee table. A large TV is positioned against the wall, complemented by a minimalist wooden console. A rug enhances the space, while natural light enters through the windows, illuminating a decorative plant in the corner.
Home in San Diego
4.92 out of 5 average rating, 103 reviews

20% OFF- Newly updated guesthome for families

Newly updated peaceful and convenient guesthome in Scripps Ranch. With a private dining room, a fully equipped private kitchen, two cozy bedrooms with desks, and a private bathroom. With central AC and 500Mbp WIFI. 1 minute's driving to a plaza with a supermarket, bank, Starbucks, and restaurants. 5 minutes’ drive to Lake Miramar. Perfect location for exploring UCSD, LaJolla Shores, San Diego Zoo, Sea World, Legoland, Balboa Park, and many other attractions in San Diego.

Guest favourite
A bright studio space features a queen bed with soft bedding, complemented by a bedside lamp. A stylish chair sits nearby, with a mirror and wall decor enhancing the room's functionality. Light tiles and neutral tones contribute to a serene ambiance.
Tiny home in Rancho Penasquitos
4.87 out of 5 average rating, 200 reviews

WOW! Private Studio Minutes To Shopping& Freeways.

Entire Private Studio Suite. Brand new up dated entire suite with 1 Queen Bed & 1 bath. Ideal for couples, solo adventurers, and business travelers. Studio is fully equipped with 1 queen bed, 1 working desk, kitchenette meant for light food warm, mini size refrigerator, single sink meant for light cup and dish wash. All new furniture, mattress, beddings. All shops, restaurants, cinema, hiking trails within minus drive about 1-5 miles away!

Top guest favourite
A sunset is captured over the ocean, with shades of orange, pink, and yellow in the sky. Silhouettes of palm trees frame the scene, while the distant pier is visible along the coastline. The tranquil atmosphere reflects a peaceful end to the day.
Guest suite in Ocean Beach
4.95 out of 5 average rating, 753 reviews

Place to Stay with Private Entrance near Beach

The room has a private entrance. It's ideally located in a residential area of Ocean Beach. 5 blocks to the beach, OB pier, and 2 blocks to village life, shops & restaurants. It has a queen bed, a small private bathroom with a shower, a fridge, TV, Wifi, microwave, etc. Guests will love the location and privacy! Beach chairs, towels, umbrellas, etc. are available for your enjoyment. Enjoy the great ocean view from the backyard.

Guest favourite
A kitchenette area is visible, featuring a small dining table with two chairs and a leather sofa nearby. Storage cabinets and a full-size refrigerator are included. A coffee maker, sink, and various kitchenware are arranged on the countertop, with decorative art hanging on the wall.
Guest suite in Mira Mesa
4.87 out of 5 average rating, 193 reviews

STUDIO 56

Entire Private Studio Suite. The entire suite is brand new and updated with 1 queen bed, 1 double bed, and 1 full bath. Quiet midtown of Mira Mesa central drive in San Diego. Studio fully equipped with 2 beds, a leather sofa, working desk, kitchenette meant for light food warm, full size refrigerator, single sink meant for light cup and dish wash All shops, restaurants, a cinema within minus drive about 2 miles away.

Popular amenities for Mira Mesa family-friendly rentals

When is the best time to visit Mira Mesa?

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Quick stats about holiday rentals that are family-friendly in Mira Mesa

  • Total holiday rentals

    Explore 100 holiday rentals in Mira Mesa

  • Nightly prices starting at

    Mira Mesa holiday rentals start at £23 per night before taxes and fees

  • Verified guest reviews

    Over 4,290 verified reviews to help you choose

  • Pet-friendly holiday rentals

    Find 40 rentals that welcome pets

  • Holiday rentals with a pool

    30 properties feature pools

  • Rentals with dedicated workspaces

    70 properties have a dedicated workspace

  • Wifi availability

    100 of Mira Mesa holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Mira Mesa rentals

  • 4.8 Average rating

    Mira Mesa stays are highly rated by guests – averaging 4.8 out of 5!