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Holiday rentals in Santa Cruz de la Sierra

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz de la Sierra

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
Apartment in Santa Cruz de la Sierra
5 out of 5 average rating, 11 reviews

2D Premium Apartment + Balcony + Garage on Ground Floor + Shared Areas – Excellent Location

💎 Premium apartment + private balcony + 80 m² garage in an exclusive and secure area, self check-in ✅️🛡. It has 2 bedrooms 🛏️ with high-end mattresses; the main one with an extra large 2×2 m bed 😴💎. 65” Smart TV 📺, surround sound 🎶, high-speed internet 📶 and air conditioning ❄️. Exterior balcony on the first floor 🌿☀️. Building with 24/7 security 👮‍♂️, panoramic pool 🏊‍♂️, gym 💪 and sky lounge 🍸✨. Close to shopping centres 🛍️, 24-hour supermarkets 🛒, clinics 🏥, and banks 🏦. Ideal for couples 🌙✨🍷❤️🍷

Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 48 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Top guest favourite
A serene outdoor area features a spacious swimming pool surrounded by a sleek stone wall. Comfortable loungers offer a relaxing spot to enjoy panoramic views of the city skyline and a colorful sunset.
Flat in Santa Cruz de la Sierra
4.99 out of 5 average rating, 70 reviews

Modern Apartment in Equipetrol with Pool and View

✨ Enjoy a comfortable stay in Equipetrol, one of Santa Cruz’s most exclusive areas. The building offers shared areas: on the 4th floor you’ll find a spacious lounge with sofa, TV, air conditioning, and a pool table, along with a swimming pool and barbecue area; on the 17th floor you can enjoy the gym, another barbecue area, and city views. The apartment includes fast 300 Mbps Wi-Fi, an in-unit washer, 4K TV, air conditioning, and a fully equipped kitchen, ideal for business or leisure stays.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 24 reviews

Equipetrol, Fantastic 2 Bedroom Apartment

¡Disfruta con tu familia del lujo y la comodidad en la mejor zona de Santa Cruz, Equipetrol! Bienvenido al exclusivo Torre ARA, donde el diseño moderno se fusiona con la funcionalidad en este elegante departamento de 2 dormitorios totalmente equipado, para tu confort. Además te ofrecemos: piscina tipo infinita, lounge, barbacoas en la azotea y seguridad 24/7. Estarás a pasos de los mejores restaurantes, cafeterías, y vida nocturna. ¡Reserva ahora y disfruta de una experiencia inolvidable!

Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 149 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favourite
An expansive rooftop pool is illuminated by soft lighting, reflecting the city skyline at night. Lounge chairs are neatly arranged along the pool's edge, and the sleek wooden deck complements the modern aesthetic of the space.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 150 reviews

Luxurious and modern apartment. Equipetrol Sky Elite

This luxurious studio is located in the Equipetrol neighborhood, Sky Elite Building, one block from the Los Tajibos Hotel; it represents the perfect combination of exclusivity and first-class amenities in the city of Santa Cruz de la Sierra, surrounded by restaurants, shops, cafes, pharmacies and supermarkets. The building offers more than 3,000 square meters of social areas including a modern gym, extensive swimming pool, barbecue, coworking, private movie theater, sauna and whirlpool.

Top guest favourite
An inviting pool area is surrounded by modern buildings, featuring lounge chairs arranged neatly along the water's edge. The pool's surface reflects the colorful lights of the surrounding structures and the evening sky, creating a tranquil atmosphere.
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 50 reviews

Green Tower 26th Floor, Luxury, Panoramic Views

Disfruta tu estadía en el airbnb mas Espacioso, amplio, mas alto de Santa Cruz y donde todo queda cerca y en el mejor edificio de la ciudad, en las instalaciones podrás disfrutar de Piscina, Sauna a Vapor, vistas espectaculares desde el piso 26 hacia el hermoso edificio Manzana 40, el iconico Rio Pirai. A Pasos de supermercado, restaurantes, malls, bancos, spa, etc… En el mismo edificio Estan los restaurantes Bellos y lujosos Cielo skay bar (rooftop), Jardin de Asia y más.

Guest favourite
An outdoor terrace is showcased, featuring a dining table surrounded by wooden chairs. A sleek kitchen area with a dark countertop is positioned nearby, while panoramic city views are framed by glass railings. Soft lighting enhances the space as the sunset casts a warm glow.
Flat in Santa Cruz de la Sierra
4.94 out of 5 average rating, 68 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A modern kitchen is showcased, featuring a sleek black countertop and stainless steel appliances. A cooking range is integrated into the design, with polished surfaces reflecting the natural light from the large windows. Views of the cityscape are visible through the window, enhancing the ambiance.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 132 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
4.94 out of 5 average rating, 18 reviews

Luxury 1-bedroom apartment, equipped and close to everything.

Discover a luxury retreat in a quiet residential area. This 1-bedroom apartment offers a contemporary design and spaciousness that is noticeable in every detail: bright spaces, fully equipped kitchen. A place designed for your rest and comfort, with a queen bed, large closets, washing machine, TV in the living room and bedroom. Prime location near malls, restaurants, pharmacies and supermarkets. Enjoy total comfort and privacy.

Guest favourite
Flat in Santa Cruz de la Sierra
4.93 out of 5 average rating, 15 reviews

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 7 reviews

Apartment 3D Macororo 13/14 • Garage, Pool and much more

Welcome to your new favorite place in Santa Cruz. Macororo Condo 13/14 Layout & amenities: 3 beds in total Living-dining room with balcony Modern kitchen with full kitchenware Equipped laundry Covered garage included free Condominium social areas 50 m pool, solarium, heated pool, jacuzzi, sauna, barbecue grills, game room, meeting room, children's game room, party room and more!

Popular amenities for Santa Cruz de la Sierra holiday rentals

Frequently Asked Questions

  • What are the best places to stay in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has stays in lively neighborhoods like Equipetrol, known for dining and nightlife, and around the city center near plazas and shops. Guests often appreciate areas with leafy streets, local cafes, and easy access to cultural sites.

  • What are the best things to do in Santa Cruz de la Sierra with kids?

    Families can explore city parks, interactive museums, and local zoos featuring native wildlife. Playgrounds and green spaces in residential neighborhoods add opportunities for outdoor fun.

  • What are some of the best things to do in Santa Cruz de la Sierra?

    Discover central plazas, explore Museo de Historia Natural Noel Kempff Mercado, and wander bustling traditional markets. The city also has botanical gardens, art spaces, and vibrant street life.

  • How is the weather in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra generally has warm, humid conditions year-round, with wetter spells in certain months and a tropical atmosphere. Lightweight clothing and sun protection are often suggested, especially for daytime outings.

  • What are the best places to visit in Santa Cruz de la Sierra?

    Explore Plaza 24 de Septiembre, admire local art at Museo de Arte Contemporáneo, and stroll the city’s botanical gardens. Markets and lively pedestrian zones add extra color to the experience.

  • What are some hiking trails in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has nature reserves and eco-parks where visitors can follow shaded trails amidst tropical plants and birds. Urban green spaces and parks also provide pathways for relaxed walks.

  • What are some family activities we can do in Santa Cruz de la Sierra?

    Families frequently explore city zoos, botanical gardens, interactive museums, and open-air playgrounds. Participating in local craft workshops or tasting fresh fruit at traditional markets brings a sense of discovery.

  • What are some of the best day trip ideas from Santa Cruz de la Sierra?

    Day trips often include exploring nature reserves, visiting Jesuit mission towns, or discovering small communities with locally rooted traditions. Eco-parks around the city provide hiking, birdwatching, and opportunities to connect with regional culture.

  • Are there any pet friendly accommodations available in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has pet-friendly vacation rentals in neighborhoods like Equipetrol, Urbarí, and around the city center. Many stays include access to green spaces and parks for walks with your pet.

  • What are some local tips for visiting Santa Cruz de la Sierra?

    Locals appreciate lightweight clothes for the heat, insect repellent, and comfortable shoes for exploring urban sights. Trying locally grown fruits at traditional markets is frequently suggested, and learning some Spanish phrases adds ease to your experience.

  • What is Santa Cruz de la Sierra known for?

    Santa Cruz de la Sierra is known for its lively main plaza, tropical botanical gardens, and dynamic blend of Indigenous and European traditions. The city’s vibrant markets, local cuisine, and arts scene are frequently highlighted.

  • What are the best hidden gems to explore in Santa Cruz de la Sierra?

    Around Santa Cruz de la Sierra, visitors often discover small artisan shops, tranquil eco-parks, and street murals tucked in residential neighborhoods. Community-run cafés and weekend craft markets add unique flavor.

  • What are the best foods to try in Santa Cruz de la Sierra?

    Local favorites include salteñas, sonso de yuca, and traditional dishes made from corn, plantain, and tropical fruits. Refreshing drinks such as mocochinchi and locally roasted coffee are often recommended.

  • What should I bring for a trip to Santa Cruz de la Sierra?

    Pack lightweight clothing, sun protection, insect repellent, and comfortable shoes for walking. Bringing a reusable water bottle and rain jacket can add convenience, especially if you plan outdoor excursions.

  • What is the nightlife in Santa Cruz de la Sierra like?

    Santa Cruz de la Sierra has lively nightlife, with bars and clubs frequently suggested around the Equipetrol neighborhood. In the city center, you can explore relaxed venues featuring live music, local cocktails, and outdoor patios.

  • What are the most popular events or festivals in Santa Cruz de la Sierra?

    Santa Cruz de la Sierra has celebrated cultural festivals, Carnaval, and regional fairs throughout the year. Music, dance, and food events are frequently suggested, especially around holidays and community celebrations.

  • Are there family friendly vacation rentals in Santa Cruz de la Sierra?

    Family-friendly vacation rentals can be found in Equipetrol, Urbarí, and the city center, many with spacious layouts and access to parks or play areas. Hosts often provide amenities for children to make visits comfortable.

  • When is the best time to visit Santa Cruz de la Sierra?

    Visitors often prefer the drier months for outdoor activities and exploring city sights, while some enjoy the lush greenery during wet seasons. Popular festivals and pleasant evenings draw many travelers throughout the year.

Quick stats about holiday rentals in Santa Cruz de la Sierra

  • Total holiday rentals

    Explore 4,450 holiday rentals in Santa Cruz de la Sierra

  • Nightly prices starting at

    Santa Cruz de la Sierra holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 57,810 verified reviews to help you choose

  • Family-friendly holiday rentals

    1,200 properties offer extra space & child-friendly amenities

  • Pet-friendly holiday rentals

    Find 1,210 rentals that welcome pets

  • Holiday rentals with a pool

    2,950 properties feature pools

  • Rentals with dedicated workspaces

    2,490 properties have a dedicated workspace

  • Wifi availability

    4,070 of Santa Cruz de la Sierra holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santa Cruz de la Sierra rentals

  • 4.7 Average rating

    Santa Cruz de la Sierra stays receive an average rating of 4.7 out of 5 from guests

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