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Apartment holiday rentals in Santa Cruz

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santa Cruz

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 156 reviews

Studio 518 - Luxury near Everything

Automatic access, 2 Air Conditioners, Washing Machine, Kitchen, Sofa and TV perfect for working all day with a green view from an 8th floor apartment in the most sought-after neighborhood in the city, Equipetrol. If you get bored you can use the pool at no cost, social areas, BBQ. If you get bored, you'll be 2 minutes away from supermarkets, pharmacies, blocks from Equipetrol's main square with renowned restaurants, 5 minutes from the Central Plaza or 5 minutes from Bolivia's largest shopping mall, Ventura Mall.

Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
An open living area is displayed, featuring a modern design with light-toned floor tiles. A comfortable seating area includes a large gray sofa, black accent chairs, and an entertainment unit with a large TV. A kitchen bar with stools adds functionality to the space.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 13 reviews

Unique apartment in the best area!

Exceptional apartment of 88 m2 in the heart of Equipetrol. Very quiet place to rest or work, but at the same time close to fun. You will have an amazing stay!! With absolutely everything, brand new: furnished and decorated, air conditioning, Wi-Fi, 55" and 48" Smart TVs, fully equipped kitchen, king-size bed, queen-size sofa bed, private laundry and drying area, and ample free parking at the entrance 24 hours a day. Beautiful swimming pool and sauna. Spacious balcony with a lovely view of the city.

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 6 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests looking for an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and safest area of Santa Cruz, this elegant apartment on the penultimate floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecues, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafés, theatres, shops and business centres. Ideal for business trips, luxury getaways or unforgettable stays.

Top guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 19 reviews

POX | Green Tower 17th Floor, Luxury in Equipetrol

✨ Live the POX experience of luxury and comfort in the heart of Equipetrol ✨ Located on the 17th floor of the exclusive Green Tower, this POX Glam apartment combines modern design, sophisticated decor and a unique panoramic view of Santa Cruz. Perfect for business travelers, couples, or leisure stays looking for a premium space with all the amenities. At POX we don't just rent apartments: we give you a home away from home. Our team is available 24/7 to help you.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.89 out of 5 average rating, 150 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

Superhost
Flat in Santa Cruz de la Sierra
4.84 out of 5 average rating, 107 reviews

new and modern apartment

Welcome to your new home in Equipetrol, the best area of Santa Cruz! This new and modern apartment offers you a cozy and comfortable space, ideal for you to enjoy your stay, whether for work or rest. Located in the heart of Equipetrol, you'll be surrounded by everything you need: supermarkets, banks, shops, pharmacies, cafes, restaurants, church and the Ventura Mall. We invite you to enjoy an unforgettable stay.

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 20 reviews

Luxury apartment opposite the Hotel Yotaú

Enjoy a unique stay in the heart of Equipetrol, the best area of the city. Located on the 13th floor, this modern apartment offers a wonderful view and a private balcony for you to relax. Fully equipped for short or long stays, designed for your maximum comfort. What's more, you can enjoy exclusive luxury social areas that will make your experience even more special.

Top guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 39 reviews

Green Tower* 27th Floor Stunning views & Luxury

Truly the highest floor in the building, this modern luxury retreat soars above the city with breathtaking panoramic views. Sleek finishes, stylish decor, and plush comforts create a refined, high-end ambiance. Whether you’re sipping wine at sunset or waking up in the clouds, this stunning high-rise sanctuary delivers an unforgettable, elevated stay.

Superhost
The exterior of a modern building is highlighted by large glass windows reflecting the sunlight. A tree with vibrant yellow flowers frames the image, while palm plants create a lush entrance. The structure showcases a contemporary architectural design.
Flat in Santa Cruz de la Sierra
4.78 out of 5 average rating, 162 reviews

Nanotec

Welcome to our apartment in Equipetrol, where comfort and convenience come together to offer you an unforgettable experience during your stay in Santa Cruz de la Sierra. Whether you're visiting the city for business or pleasure, our apartment is the perfect place to enjoy all that this vibrant city has to offer. We hope to have you as a guest soon!

Popular amenities for Santa Cruz apartment rentals