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Family-friendly holiday rentals in Santa Cruz

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Santa Cruz

Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

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Guest favourite
Flat in Santa Cruz de la Sierra

Beautiful, spacious and unique apartment in the best area.

Create unforgettable memories in this unique and family-friendly accommodation. Exceptional 122 m2 apartment in the heart of Equipetrol. A very quiet place to relax or work, but also close to entertainment. You'll have an amazing stay! Spacious, modern, furnished and decorated apartment with air conditioning, Wi-Fi, 65" and 55" 4K Smart TVs, kitchen, 2 bedrooms, 3 bathrooms, private washing and drying area, and ample free parking at the entrance 24 hours a day. Beautiful swimming pool and sauna. Large balcony with a lovely view of the city.

5.0 out of 5 average rating, 8 reviews
Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

4.98 out of 5 average rating, 56 reviews
Top guest favourite
Flat in Santa Cruz de la Sierra

Macororo | 3D + heated pool

Enjoy a comfortable and stylish stay in this spacious three-bedroom apartment in Macororo 13/14, on Av. Los Cusis. Great for families, groups, and traveling for work. • Heated pool and social areas • Free Private Parking • Fast Wi-Fi. • Equipped kitchen • Washer & Dryer • Smart TV. Just a few steps away, you'll find a 24-hour supermarket, Starbucks, restaurants, a shopping centre and a gym opposite the building. A comfortable, safe space designed for an excellent stay.

4.98 out of 5 average rating, 83 reviews
Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

4.93 out of 5 average rating, 82 reviews
Guest favourite
An outdoor terrace features sleek wooden decking, complemented by low seating arrangements and lush greenery. A tranquil water feature runs along one side, reflecting the surrounding cityscape. Modern buildings rise in the background under a clear, blue sky.
Flat in Santa Cruz de la Sierra

Elegant family apartment in Equipetrol

Have fun with the family in this new, central, and stylish accommodation. Beautiful and modern apartment located in the best area of Santa Cruz. Just a few steps away from the city's best restaurants, pharmacies, supermarkets, cafes, nightclubs, and shopping malls. Ideal for families, a group of friends, or two couples. You can have all the comforts of a luxury apartment for a cozy and pleasant stay. The building's common areas are a dream!

4.97 out of 5 average rating, 59 reviews
Guest favourite
Flat in Santa Cruz de la Sierra

Equipetrol, Fantastic 2 Bedroom Apartment

Enjoy luxury and comfort with your family in the best area of Santa Cruz, Equipetrol! Welcome to the exclusive ARA Tower, where modern design merges with functionality in this stylish 2 bedroom apartment fully equipped, for your comfort. We also offer: infinity pool, lounge, rooftop barbecue and 24/7 security. You'll be just a stone's throw away from the best restaurants, cafés and nightlife. Book now and have an unforgettable experience!

5.0 out of 5 average rating, 33 reviews
Guest favourite
Flat in Santa Cruz de la Sierra

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

4.94 out of 5 average rating, 32 reviews
Guest favourite
Cottage in Samaipata

EcoHouse · Swimming pool · Nature · Tranquillity · Samaipata

A living-earth sanctuary on Samaipata Mountain. Handcrafted using natural materials, with a Bolivian soul. Welcome to CASA CACTUS — fully equipped and personalised for a stay surrounded by natural luxury. 🏊 Swimming pool · 🛜 Starlink · 🌿 Nature · Weekly and monthly DEALS *see below or contact us*. A space to truly unwind. For writing. For slow cooking. To work online and offline. To look at the mountains without haste.

4.93 out of 5 average rating, 30 reviews
Top guest favourite
Flat in Santa Cruz de la Sierra

Luxury & Comfort: Apartment with Private Balcony

Enjoy a luxury experience in the heart of Equipetrol. This elegant apartment combines design, comfort and carefully selected details, with a private balcony and a prime location next to Green Tower. Enjoy incredible social areas with a luxury pool, a modern co-working space, and areas designed for you to relax, work, and have fun. Everything you need for a sophisticated, comfortable and unforgettable stay in Santa Cruz.

4.88 out of 5 average rating, 105 reviews
Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

4.89 out of 5 average rating, 154 reviews
Guest favourite
Flat in Santa Cruz de la Sierra

The best view of Santa Cruz

From this apartment in the best area of Santa Cruz (Equipetrol Norte, in the business center) you will have the best apartment with a pleasant climate. It is located on the 16th floor, unsurpassed views and sunsets. The whole group will enjoy easy access to supermarkets, restaurants, pharmacies, banks, transportation, paddle courts, etc. The Ventura mall is steps away from the apartment.

4.94 out of 5 average rating, 17 reviews
Guest favourite
The lobby displays a modern aesthetic with concrete walls and a large piece of colorful artwork. A welcoming reception desk is prominent, accompanied by pendant lighting. A cozy seating area features a gray sofa and a round table, complemented by potted greenery and a light flooring.
Flat in Santa Cruz de la Sierra

Quartier Luxury 3

Luxurious apartment with an unbeatable location in Equipetrol. The space is fully furnished and you will be surrounded by a wide variety of restaurants, shops, close to major shopping malls, among others. The building has social areas on the top floor. Whether you're here for business or pleasure, our location will allow you to make the most of your time in the city.

4.81 out of 5 average rating, 191 reviews

Popular amenities for Santa Cruz family-friendly rentals