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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Top guest favourite
A modern living area is furnished with a gray sofa and a brown accent chair. A wooden coffee table sits on a textured rug in front of the sofa. Natural light floods in through large windows, illuminating the open layout that connects to an equipped kitchen.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 55 reviews

Luxury and comfort in every detail

This apartment combines luxury, style, and comfort in every detail. Designed as a boutique hotel, it offers a unique experience with impeccable finishes, an equipped kitchen, a cozy living room, spacious bedrooms, and a beautiful balcony to relax. Located in the heart of Equipetrol and a short walk from restaurants, shops and attractions. Perfect for business trips or relaxation, this modern and elegant space is ideal for relaxing and enjoying an unforgettable stay. You'll love it! Parking is included!

Guest favourite
A modern living area is displayed, featuring a comfortable sofa and a green accent pouf. A dining table is situated nearby. Floor-to-ceiling windows offer a view of the greenery outside, allowing natural light to fill the space. The kitchen is equipped with sleek appliances.
Flat in Santa Cruz de la Sierra
4.91 out of 5 average rating, 155 reviews

Studio 518 - Luxury near Everything

Acceso automático, 2 Aires Acondicionados, Lavadora, Cocina, Sofa y TV perfecto para trabajar todo el día con una vista verde de un 8 piso desde el barrio más cotizado de la ciudad, Equipetrol. Si te aburres puedes usar la piscina sin costo, áreas sociales, asado BBQ. Si te aburres más estarás a 2 minutos de Supermercados, Farmacias a cuadras de la principal de Equipetrol con Restaurantes renombrados, a 5 min de la Plaza Central o a 5 min del shopping más grande de Bolivia, Ventura Mall.

Top guest favourite
A modern interior is presented, featuring a cozy seating area with a dark sofa, complemented by a circular coffee table. A wooden divider offers separation from the sleeping area, where a spacious bed with neutral bedding is visible. Natural light fills the space from the nearby window.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 45 reviews

SkyLuxia New Equipetrol Apartment - Safe & Luxurious

Enjoy and relax in this new, quiet and elegant space for two people. Located in Equipetrol, the best area of Santa Cruz, close to restaurants and shopping centers. It offers comfort, convenience and safety. You'll find: WiFi, 55” Smart TV, Cable TV, Air Conditioning, Washer + Dryer. ✔ Large swimming pool and sauna ✔ Gym ✔ Meeting room ✔ 24/7 Reception Fully equipped with towels, shampoo, conditioner, soap, toilet paper, tea, coffee, sugar, salt and oil.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 76 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 12 reviews

Comfortable and modern apartment in Equipetrol with fast WiFi

Stay in the best part of the city – Equipetrol Norte This studio is ideal if you’re looking for comfort, style and a convenient location. 🛏️ Modern, stylish and fully equipped space 💻 Perfect for remote working and corporate stays High-Speed 📶 Internet 📍 Unbeatable location: Just a few minutes from Ventura Mall, Hipermaxi Just a short walk from the Fidalga, Green Tower and Manzano 40 supermarkets Surrounded by cafés, restaurants and business centres

Guest favourite
A tranquil studio space features a spacious bed dressed with light linens and decorative pillows. A cozy seating area includes a dark grey sofa and a round wooden coffee table. Natural light streams through a large window draped with light curtains, highlighting a wall accentuated with soft textures.
Apartment in Santa Cruz de la Sierra
4.85 out of 5 average rating, 299 reviews

Quiet Monoenvironment in Equipetrol

Enjoy the simplicity of this quiet studio in the heart of Equipetrol, where you can be close to restaurants, supermarkets, squares, churches, the business center if you come for work in the same way. In your leisure time, the studio has Wify, TV, Netflix, kitchen, microwave, oven, refrigerator and everything you need to be comfortable inside the building, since in the social areas you can enjoy the pool, churrasqueras, game room and coWork

Top guest favourite
A comfortable sleeping area features a spacious bed adorned with soft pillows and a decorative throw. Warm bedside lamps illuminate the space, while large windows offer views of the surrounding cityscape and allow natural light to brighten the room.
Flat in Santa Cruz de la Sierra
4.98 out of 5 average rating, 135 reviews

13° SmartLife - Luxury Equipetrol

Welcome to your sanctuary of sophistication and elegance at the top. This exceptionally cozy and stylish studio on the 13th floor invites you to experience luxury and comfort at their finest. Ready to experience the perfect combination of sophistication, comfort, and technology? Don't miss out on this unique opportunity. Book your stay at "13° SmartLife" and be seduced by the charm of this incomparable space! Your urban retreat awaits.

Guest favourite
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 25 reviews

POX: Green Tower 16th floor | Luxury and elegance - 2H

Live the POX experience! We present our largest apartment in the iconic Green Tower, the most exclusive and luxurious building in Santa Cruz. A fully equipped apartment for you to live a unique experience with your family or friends. Be dazzled by the best view of the city, 24/7 service and close to banks, restaurants, shopping malls, everything you need meters away. We'll make sure you have a great stay, welcome to POX!

Guest favourite
Cottage in Samaipata
5 out of 5 average rating, 23 reviews

EcoHouse · Swimming pool · Nature · Tranquillity · Samaipata

A living-earth sanctuary on Samaipata Mountain. Handcrafted using natural materials, with a Bolivian soul. Welcome to CASA CACTUS — fully equipped and personalised for a stay surrounded by natural luxury. 🏊 Swimming pool · 🛜 Starlink · 🌿 Nature · Weekly and monthly DEALS *see below or contact us*. A space to truly unwind. For writing. For slow cooking. To work online and offline. To look at the mountains without haste.

Guest favourite
A bright and airy bedroom features a spacious bed adorned with white bedding. Soft, sheer curtains filter natural light from the large window. A bedside lamp provides additional illumination, while a delicate arrangement of orchids adds a touch of elegance to the serene ambiance.
Flat
4.86 out of 5 average rating, 22 reviews

Luxury apartment with swimming pool in Equipetrol

Enjoy a luxury experience in this exclusive apartment in the heart of Equipetrol, the best financial and leisure area of ​​Santa Cruz. Close to hospitals, restaurants and cafes, but on a quiet street. Swimming pool, 2 barbecues, gym and chill out area. All social areas with stunning views. You can find more photos, videos and recommendations of places to eat or visit on the Insta account: deluxe santacruz bolivia

Superhost
Flat in Santa Cruz de la Sierra
4.84 out of 5 average rating, 106 reviews

new and modern apartment

Welcome to your new home in Equipetrol, the best area of Santa Cruz! This new and modern apartment offers you a cozy and comfortable space, ideal for you to enjoy your stay, whether for work or rest. Located in the heart of Equipetrol, you'll be surrounded by everything you need: supermarkets, banks, shops, pharmacies, cafes, restaurants, church and the Ventura Mall. We invite you to enjoy an unforgettable stay.

Top guest favourite
Flat in Santa Cruz de la Sierra
5 out of 5 average rating, 18 reviews

Luxury apartment opposite the Hotel Yotaú

Enjoy a unique stay in the heart of Equipetrol, the best area of the city. Located on the 13th floor, this modern apartment offers a wonderful view and a private balcony for you to relax. Fully equipped for short or long stays, designed for your maximum comfort. What's more, you can enjoy exclusive luxury social areas that will make your experience even more special.

Popular amenities for Santa Cruz holiday rentals