
Guest house holiday rentals in Charleston
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Charleston
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Charleston
Family-friendly guest house rentals

Cozy Apartment in Mount Pleasant

Bungalow Under The Oaks

Riverland Terrace Guesthouse

The Condon Carriage | Cozy Downtown Escape

Creekside Cottage (Tiny Home)

The Cottage On Opal 2BR 1BA

Daniel Island Getaway

Urban Oasis, West of the Ashley
Guest house rentals with a patio

Quaint Cottage Studio in Ashley Forest (Avondale).

*Old Village/Shem Creek Charmer*NEW 2BR Guesthouse

2 King beds 2 Bath*Gardens* Downtown Summerville

Spacious 1 bedroom cottage in Avondale

Driftwood Cottage

My Happy Place

Cozy Cottage! 5 mins from Kiawah!

Walk to restaurants! New, beautiful & clean home
Guest house rentals with a washing machine and dryer

Peaceful Garden Cottage Retreat

Island Oasis Hideaway | Easy Beach & City Access

Beach, downtown, Alhambra Hall weddings so close!

Cozy Cottage w Games, Firepit, Grill, and More!

Charming Guest Cottage in Old Mount Pleasant, SC

The Guesthouse at Old Orchard

Old Mt. Pleasant/Shem Creek close to Sullivans/DT

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!
Quick stats about guest house rentals in Charleston
Total rentals
220 properties
Total number of reviews
26K reviews
Family-friendly rentals
30 properties are a good fit for families
Pet-friendly rentals
50 properties allow pets
Rentals with a pool
10 properties have a pool
Rentals with dedicated workspaces
100 properties have a dedicated workspace
Destinations to explore
- Saint Johns River Holiday rentals
- Western North Carolina Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Jacksonville Holiday rentals
- Pigeon Forge Holiday rentals
- Cape Fear River Holiday rentals
- North Myrtle Beach Holiday rentals
- Family-friendly rentals Charleston
- Beachfront rentals Charleston
- Bed and breakfasts Charleston
- Rentals with a hot tub Charleston
- Rentals with beach access Charleston
- Beach house rentals Charleston
- Rentals with outdoor seating Charleston
- Private suite rentals Charleston
- Rentals with pools Charleston
- House rentals Charleston
- Flat rentals Charleston
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- Pet-friendly rentals Charleston
- Rentals with breakfast Charleston
- Apartment rentals Charleston
- Mansion rentals Charleston
- Rentals with an accessible-height toilet Charleston
- Rentals with an EV charger Charleston
- Rentals with a fireplace Charleston
- Fitness-friendly rentals Charleston
- Tiny house rentals Charleston
- Rentals with a firepit Charleston
- Villa rentals Charleston
- Lakehouse rentals Charleston
- Rentals with a washing machine and dryer Charleston
- Rentals with an accessible-height bed Charleston
- Rentals with a kayak Charleston
- Hotel rentals Charleston
- Rentals with lake access Charleston
- Rentals with a patio Charleston
- Townhouse rentals Charleston
- Luxury rentals Charleston
- Guest house rentals Charleston County
- Guest house rentals South Carolina
- Guest house rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- The Golf Club at Wescott Plantation
- Waterfront Park
- Shem Creek Park
- Harbor Island Beach
- Hampton Park
- Angel Oak Tree
- The Charleston Museum
- Secession Golf Club
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Seabrook Island Beach
- Hunting Island Beach
- The Beach Club
- White Point Garden
- Charleston Aqua Park
- Seabrook Beach
- Whirlin' Waters Adventure Waterpark
- Things to do Charleston
- Food and drink Charleston
- Nature and outdoors Charleston
- Sightseeing Charleston
- Tours Charleston
- Sports activities Charleston
- Art and culture Charleston
- Things to do Charleston County
- Tours Charleston County
- Sports activities Charleston County
- Nature and outdoors Charleston County
- Sightseeing Charleston County
- Art and culture Charleston County
- Food and drink Charleston County
- Things to do South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Art and culture South Carolina
- Sports activities South Carolina
- Sightseeing South Carolina
- Wellness South Carolina
- Tours South Carolina
- Food and drink South Carolina
- Things to do United States
- Tours United States
- Sightseeing United States
- Entertainment United States
- Sports activities United States
- Wellness United States
- Food and drink United States
- Art and culture United States
- Nature and outdoors United States