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Guest house holiday rentals in James Island

Find and book unique guest house rentals on Airbnb

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Popular amenities for guest house rentals in James Island

Family-friendly guest house rentals

Guest favourite
Guest house in Charleston
4.92 out of 5 average rating, 706 reviews

Island Oasis—Near Downtown

SarahRating, 5 starstoday
The place that Chris provided was excellent! Everything is super clean and looks exactly like the photos online. We loved how this location was right in the middle of all the activities we had planned in any direction. Chris was super easy to communicate with and is very responsive. We didn’t use the grill but it’s great there was one available. Loved that there was also beach chairs and a beach umbrella for when we went the beach. His dog Django is the best and greeted us every morning and is such an easy going pup! We would definitely stay here again.
Top guest favourite
Guest house in Charleston
4.93 out of 5 average rating, 760 reviews

Charleston's Coolest Neighborhood

ShannonRating, 5 stars6 days ago
Clean and comfortable! Shower had lots of power and ac worked great! Located in a cute area with lots of unique shopping and food options within minutes. Plus it’s a short drive to downtown Charleston which has many more options.
Top guest favourite
Guest house in Summerville
4.88 out of 5 average rating, 796 reviews

New Loft in Historic Summerville

AmyRating, 5 stars4 days ago
We loved our stay at Jacquelynn's! We had to travel with our two older, yet anxious, dogs for a wedding and it turned out to be the perfect place for us. The loft is detached from the home, making it much more private to go to and from. The place was spotless with cute decor. Even though it is a smaller space, she has everything you need to make your stay comfortable. Lots of towels and blankets as well as silverware, coffee pot, and mugs. I was pleasantly surprised at how the bathroom was actually quite spacious for the small space. The most important and best part for us was the peace and quiet. We typically have to worry about outside noise as our dogs will bark at any and every noise they hear. But the loft is nestled in such a quiet and quaint neighborhood, making it perfect for anyone with anxiety ridden dogs. I highly recommend Jacquelynn's loft!
Guest favourite
Guest house in Mount Pleasant
4.94 out of 5 average rating, 251 reviews

Green Garden Studio @greengardenstudio2017

ShawnRating, 5 stars2 weeks ago
My wife and I stayed here for a long weekend during my families wedding. Place was just what we were looking for. Would definitely stay here again if we visit Charleston again! Host was very responsive and even let me borrow their personal iron. 5 stars!!
Top guest favourite
Guest house in Charleston
4.99 out of 5 average rating, 293 reviews

Spacious Daniel Island Apartment

NelleRating, 5 stars3 days ago
We had a wonderful stay at David’s. The space was exactly what we were looking for - clean, quiet, and comfortable. Daniel Island is beautiful, and downtown Charleston and Mount Pleasant are both very accessible by car/Uber. David was very communicative and a great host - we would love to stay here again!
Guest favourite
Guest house in Charleston
4.91 out of 5 average rating, 362 reviews

Mother in Law in James Island Riverland Terrace

BradRating, 5 stars6 days ago
Very gracious hosts and cute guest apartment convenient to Charleston. Property is beautifully landscaped and is very private and quiet. We enjoyed our stay.
Superhost
Guest house in Charleston
4.84 out of 5 average rating, 118 reviews

Romantic Beach Style Cottage close to everything!

NatalieRating, 5 stars3 days ago
Clean & conscious hosts! Mindful of needs that may crop up, lovely home & family. Flexible! Perfect oasis away from the bustle of Charleston.
Top guest favourite
Guest house in Mount Pleasant
4.98 out of 5 average rating, 133 reviews

5 STAR 1bd/1ba Shem Creek Retreat in #1 MtP area!

AndrewRating, 5 stars1 week ago
Amazing treehouse in quiet and beautiful neighborhood, just wow! Short distance to shem creek that has plenty of restaurants, night life, and views. We took the bikes down a few times, only 5-10 minutes. Then you get to come home to peace and quiet. One of the most beautiful neighborhoods we have ever been in. Easy Uber into Charleston. If you want to be close to the action but not right in the middle of it, this is the place for you!

Guest house rentals with a patio

Guest favourite
Guest house in Charleston
4.95 out of 5 average rating, 38 reviews

Secret Garden Guesthouse

RachelleRating, 5 stars3 days ago
Elizabeth & Jason were wonderful hosts to my husband and myself. The accommodations were pristine and quiet. We thoroughly enjoyed the peacefulness of the backyard/patio area! The location was very centralized to the downtown area. We would highly recommend this home to our family and friends! Don & Rocky
Guest favourite
Guest house in Charleston
4.94 out of 5 average rating, 236 reviews

Quaint Cottage Studio in Ashley Forest (Avondale)

JenniferRating, 5 stars1 week ago
John and his family offer a cozy place to rest after exploring the nearby neighborhoods by foot and the region by car. A comfy bed, a responsive host, a central location and great local recommendations were highlights.
Top guest favourite
Guest house in Summerville
4.99 out of 5 average rating, 73 reviews

Hearts & Dreams Peaceful Family Retreat w/ pool

AbigailRating, 5 stars1 week ago
Perfect spot for a family with young kids! Plenty for us to enjoy outdoors in the beautiful South Carolina weather. Hosts were very gracious!
Guest favourite
Guest house in Charleston
5 out of 5 average rating, 5 reviews

Stylish Carriage House+Pool House

KylieRating, 5 stars2 weeks ago
Jessie & Robin were PHENOMENAL hosts. Our stay wasn’t long but it was peaceful, clean and just what we were looking for. The space was exactly as described. They were quick to respond and were proactive at check in and check out. Our time in Charleston was wonderful and the stay only added to that! If we find our way back to Charleston I will be booking with them again.
Guest favourite
Guest house in Charleston
4.95 out of 5 average rating, 65 reviews

Country in the City, "The Outback"

BaileyRating, 5 stars3 days ago
Staying at the Outback was an absolute pleasure. We enjoyed the pool, Sue’s adorable pup and her kindness. She made us feel right at home and we couldn’t have asked for a better place to rest our heads. Thanks so much Sue!
Top guest favourite
Guest house in Johns Island
4.97 out of 5 average rating, 115 reviews

Driftwood Cottage

MeriRating, 5 stars4 days ago
Terry made staying at the Driftwood Cottage easy. Everything was clean and comfortable. Nice placce about 25 minutes outside of Charleston. Perfect place for exploring the area. Terry introduced himself and made sure everything was ok. Then I had complete privacy. Perfect host. Would stay at again.
Guest favourite
Guest house in North Charleston
4.92 out of 5 average rating, 131 reviews

My Happy Place

BridgetRating, 5 stars3 days ago
We loved our stay at the pool house! It had everything we needed and the location was great. I would highly recommend it!
Top guest favourite
Guest house in Charleston
4.99 out of 5 average rating, 153 reviews

The James: “Tiny” Home b/w Downtown & Folly

AutumnRating, 5 stars1 week ago
where do I begin? we LOVED this place! it was so clean, the beds were comfortable, and it was in a quiet neighborhood! we met Caitlin + Spencer the first day & they were SO kind! they have gone above and beyond to the attention to detail! they left us a bottle of Prosecco for our celebratory trip, a dog treat for Luna, & the sweetest handwritten letter! everything you might need they had! we are so obsessed with this cute Airbnb & we’ll definitely stay here again next time we stay in Charleston! Luna, our golden girl, also approved! Thanks so much for the beautiful stay Caitlin and Spencer we enjoyed it so much! 🩵🐶🐚🌴

Guest house rentals with a washing machine and dryer

Guest favourite
Guest house in Charleston
4.85 out of 5 average rating, 121 reviews

CHS Guest house w/ Pool on Golf Course

KarenRating, 5 stars3 weeks ago
The home was neat & clean, conveniently located, private, and quiet. We had so much fun visiting many parts of Charleston with the guest house as our homebase. The home had everything our small family needed for our stay and more! Alicia was a gracious, respectful, and responsive host. She even brought extra supplies to us in case we needed them! We would welcome the opportunity to be a guest with her again.
Top guest favourite
Guest house in Mount Pleasant
4.99 out of 5 average rating, 147 reviews

Groves Carriage House, near Shem Creek

JimiRating, 5 stars1 week ago
Wonderful, responsive hosts. This above garage unit has everything you need. The neighborhood is very accessible to anywhere you want to go. 5 minutes from Shem Creek. 15 minutes to Sullivan’s Island or Isles of Palms. Roughly 10-15 minutes from Downtown Charleston. The hosts were very helpful with any of my simple needs. I would definitely stay here again.
Top guest favourite
Guest house in Mount Pleasant
4.99 out of 5 average rating, 150 reviews

Beach, downtown, Alhambra Hall weddings so close!

ColleenRating, 5 stars3 days ago
Great spot to stay in Mt Pleasant!
Top guest favourite
Guest house in Johns Island
4.95 out of 5 average rating, 100 reviews

Leisure Lane-Private Apt on 22 acre Horse Farm

ChristineRating, 5 stars3 days ago
Absolutely amazing place! It’s quiet and a nice getaway from the city, but yet not too far to still see the sights. What you see in the photos is exactly what you get. We were so happy with the apartment, it’s clean, very comfortable and well thought out. A perfect place if you want some quiet after seeing Charleston for the day. Don’t hesitate, this place is perfect! Thanks Megan, you were an incredible host!
Top guest favourite
Guest house in Mount Pleasant
4.98 out of 5 average rating, 247 reviews

Cozy Apartment in Mount Pleasant

ElizabethRating, 5 stars4 days ago
We felt right at home from the moment we arrived. The apartment is beautifully appointed, comfortably furnished, and spotlessly clean. The kitchen had everything we needed. We appreciated the comfortable bed and how quiet the neighborhood was, while being so convenient to restaurants, shops, and everything the area has to offer. We also very much enjoyed meeting our hosts, who were so welcoming.
Guest favourite
Guest house in Mount Pleasant
4.94 out of 5 average rating, 107 reviews

Private Coastal Cottage-Near Beaches & Charleston!

ZacharyRating, 5 stars8 months ago
Thank you again for hosting us. The place was in a perfect location, and you all were very accommodating. Great storage if bringing a boat down, and Jaime and her husband are very welcoming. Would recommend this place to all
Top guest favourite
Guest house in Charleston
5 out of 5 average rating, 252 reviews

James Island "La Casita" Nestled btw Beach & City

ValarieRating, 5 stars2 weeks ago
John and Leah’s place was wonderful to stay in. Looks just like the pictures, beautiful bathroom, comfy couch and bed. We actually cooked breakfast every morning, and a couple of dinners too! We loved coming back to the Airbnb after a day of activity!! It was quiet, peaceful and we felt rested just by being there! We would definitely stay again next time we visit!!
Top guest favourite
Guest house in Summerville
4.97 out of 5 average rating, 258 reviews

Summerville’s Tiny Oak Hideaway

BrittanyRating, 5 stars1 week ago
Loved staying in this cute little cottage! Perfect amount of space for myself, a friend, and her newborn! Very peaceful and in walking distance to local coffee shops + more! Justin sent recommendations and the check in was easy. Will be back :)

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