
Guest house holiday rentals in Mount Pleasant
Find and book unique guest house rentals on Airbnb
Top-rated guest house rentals in Mount Pleasant
Guests agree: these guest house rentals are highly rated for location, cleanliness and more.
Holiday rentals for every style
Get the amount of space that is right for you
Popular amenities for guest house rentals in Mount Pleasant
Family-friendly guest house rentals

The Crescent Moon | A Cozy Haven for Two

The Olive FROG in Park Circle! 3 min walk to FUN!

Riverland Terrace Guesthouse

New Loft in Historic Summerville

Cottage apartment near beach and downtown

Parkway Place - Entire Studio Apartment - Sleeps 2

Creekside Cottage (Tiny Home)

The Cottage On Opal 2BR 1BA
Guest house rentals with a patio

Quaint Cottage Studio in Ashley Forest (Avondale).

Studio 77 in dt Charleston with bikes

Farm Stay w Gardens, Cute Animals, Firepit + Porch

Spacious 1 bedroom cottage in Avondale

Driftwood Cottage

My Happy Place

The Violet Villa w/no cleaning fee

The James: “Tiny” Home b/w Downtown & Folly
Guest house rentals with a washing machine and dryer

Cozy Apartment in Mount Pleasant

Cozy Cottage w Games, Firepit, Grill, and More!

Private Coastal Cottage-Near Beaches & Charleston!

James Island "La Casita" Nestled btw Beach & City

Summerville’s Tiny Oak Hideaway

Cozy Park Circle, Charleston Guest House

Charming Guest Cottage in Old Mount Pleasant, SC

The Guesthouse at Old Orchard
Quick stats about guest house rentals in Mount Pleasant
Total rentals
50 properties
Total number of reviews
6.6K reviews
Family-friendly rentals
10 properties are a good fit for families
Pet-friendly rentals
10 properties allow pets
Rentals with dedicated workspaces
20 properties have a dedicated workspace
Wifi availability
50 properties include access to wifi
Destinations to explore
- Saint Johns River Holiday rentals
- Western North Carolina Holiday rentals
- Atlanta Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Pigeon Forge Holiday rentals
- Jacksonville Holiday rentals
- Cape Fear River Holiday rentals
- Private suite rentals Mount Pleasant
- Rentals with an EV charger Mount Pleasant
- Flat rentals Mount Pleasant
- House rentals Mount Pleasant
- Beachfront rentals Mount Pleasant
- Rentals with a hot tub Mount Pleasant
- Pet-friendly rentals Mount Pleasant
- Rentals with pools Mount Pleasant
- Rentals with a washing machine and dryer Mount Pleasant
- Rentals with beach access Mount Pleasant
- Rentals with outdoor seating Mount Pleasant
- Rentals with a kayak Mount Pleasant
- Townhouse rentals Mount Pleasant
- Rentals with a fireplace Mount Pleasant
- Apartment rentals Mount Pleasant
- Fitness-friendly rentals Mount Pleasant
- Waterfront rentals Mount Pleasant
- Rentals with a firepit Mount Pleasant
- Rentals with breakfast Mount Pleasant
- Villa rentals Mount Pleasant
- Rentals with a patio Mount Pleasant
- Luxury rentals Mount Pleasant
- Family-friendly rentals Mount Pleasant
- Guest house rentals Charleston County
- Guest house rentals South Carolina
- Guest house rentals United States
- Park Circle
- Hunting Island State Park Beach
- Sullivan's Island Beach
- Bulls Island
- Middleton Place
- James Island County Park
- Waterfront Park
- The Golf Club at Wescott Plantation
- Shem Creek Park
- Angel Oak Tree
- Harbor Island Beach
- Hampton Park
- The Charleston Museum
- Driftwood Beach
- Morris Island Lighthouse
- Isle of Palms Beach
- Seabrook Island Beach
- Hunting Island Beach
- Charleston Aqua Park
- Gibbes Museum of Art
- White Point Garden
- Seabrook Beach
- Whirlin' Waters Adventure Waterpark
- Splash Zone Waterpark At James Island County Park
- Things to do Mount Pleasant
- Nature and outdoors Mount Pleasant
- Things to do Charleston County
- Nature and outdoors Charleston County
- Sightseeing Charleston County
- Tours Charleston County
- Food and drink Charleston County
- Art and culture Charleston County
- Sports activities Charleston County
- Things to do South Carolina
- Entertainment South Carolina
- Nature and outdoors South Carolina
- Wellness South Carolina
- Sightseeing South Carolina
- Food and drink South Carolina
- Sports activities South Carolina
- Art and culture South Carolina
- Tours South Carolina
- Things to do United States
- Wellness United States
- Food and drink United States
- Tours United States
- Art and culture United States
- Entertainment United States
- Nature and outdoors United States
- Sightseeing United States
- Sports activities United States