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Holiday rentals in Santa Cruz

Find and book unique accommodation on Airbnb

Top-rated holiday rentals in Santa Cruz

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
Flat in Santa Cruz de la Sierra
4.9 out of 5 average rating, 21 reviews

Luxury apartment in Equipetrol | SKY Moon

Enjoy an experience with a unique style, just a stone's throw from Mall Ventura, Mz-40, Green Tower and the Hotel Camino Real. Elegant studio in SKY MOON, Equipetrol Norte. Furnished studio with a bed, a comfortable sofa, a desk, a fully equipped kitchen, a private bathroom and a balcony. Great for business trips or rest. Enjoy hotel-style amenities: pool, sauna, gym, coworking, billiards, paddle tennis court and terrace with fireplace in the best business area of Santa Cruz. Book and enjoy the experience today

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 7 reviews

Skyline Luxury • Rooftop, Piscina, Billar & Lounge

Designed for discerning guests looking for an experience superior to a 5-star hotel. Located in Equipetrol, the most exclusive and safest area of Santa Cruz, this elegant apartment on the penultimate floor offers a double balcony with unique views! Premium amenities such as a sky pool, lounge, pool table, barbecues, fully equipped gym, and more! Surrounded by the best restaurants, bars, cafés, theatres, shops and business centres. Ideal for business trips, luxury getaways or unforgettable stays.

Guest favourite
A contemporary entryway featuring sleek, metallic walls and smooth marble flooring. A minimalist reception desk with soft ambient lighting displays the name 'NUU.' A large potted plant adds a touch of greenery, while well-placed lighting creates a bright atmosphere.
Flat in Santa Cruz de la Sierra
4.92 out of 5 average rating, 79 reviews

apartment with an excellent view

Apartment located in the Equipetrol area. Located on the 13th floor, you'll enjoy stunning views in a comfortable and elegant atmosphere. This apartment has two bedrooms and two bathrooms, ideal for families or groups. It's fully equipped to make you feel at home. Among the building's amenities, you will find a cinema, a swimming pool, a barbecue area, an equipped gym, a playground, and parking for visitors. Easy access to restaurants, shops, and attractions.

Top guest favourite
A modern living area is presented, featuring a comfortable gray sofa facing a large window with city views. A sleek, wall-mounted television is positioned above a stylish wooden console. Natural light fills the room, complemented by decorative plants and minimalist artwork.
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 55 reviews

Xquisite Suite - 1 Room Equipetrol North

Discover elegance in this cozy 1-bedroom apartment with dreamy views. Experience the luxury of extreme equipment with a 65" 4K HDR Smart TV in the living room and another 50" TV in the bedroom, powerful air conditioning equipment, a washing machine, and necessary appliances, an Ultra Comfort Queen bed, a changing table and a dresser, as well as home automation and Alexa to fulfill your orders. Experience the synthesis of modernity like never before, book NOW!

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 12 reviews

Comfortable and modern apartment in Equipetrol with fast WiFi

Stay in the best part of the city – Equipetrol Norte This studio is ideal if you’re looking for comfort, style and a convenient location. 🛏️ Modern, stylish and fully equipped space 💻 Perfect for remote working and corporate stays High-Speed 📶 Internet 📍 Unbeatable location: Just a few minutes from Ventura Mall, Hipermaxi Just a short walk from the Fidalga, Green Tower and Manzano 40 supermarkets Surrounded by cafés, restaurants and business centres

Superhost
Cottage in Samaipata
4.96 out of 5 average rating, 25 reviews

EcoHouse · Swimming pool · Nature · Tranquillity · Samaipata

A living-earth sanctuary on Samaipata Mountain. Handcrafted using natural materials, with a Bolivian soul. Welcome to CASA CACTUS — fully equipped and personalised for a stay surrounded by natural luxury. 🏊 Swimming pool · 🛜 Starlink · 🌿 Nature · Weekly and monthly DEALS *see below or contact us*. A space to truly unwind. For writing. For slow cooking. To work online and offline. To look at the mountains without haste.

Top guest favourite
A spacious bed is positioned against a large window, offering a view of the cityscape. Soft pillows and a neatly arranged blanket enhance the comfort of the sleeping area. A small rug lies on the floor, complementing the modern decor.
Flat in Santa Cruz de la Sierra
4.89 out of 5 average rating, 150 reviews

Comfortable/modern studio apartment beautiful view 300Mbps

Welcome to the most active area of Santa Cruz! The price already includes all fees, you won't pay anything extra in the app. The apartment is a fully equipped, modern and comfortable studio. It has a double bed and a sofa bed in addition to a private bathroom, washer/dryer, kitchen and all the necessary appliances. Wi-Fi Internet, cable TV and NETFLIX. Close to supermarkets, the best restaurants in town and malls.

Superhost
Flat in Santa Cruz de la Sierra
4.83 out of 5 average rating, 110 reviews

new and modern apartment

Welcome to your new home in Equipetrol, the best area of Santa Cruz! This new and modern apartment offers you a cozy and comfortable space, ideal for you to enjoy your stay, whether for work or rest. Located in the heart of Equipetrol, you'll be surrounded by everything you need: supermarkets, banks, shops, pharmacies, cafes, restaurants, church and the Ventura Mall. We invite you to enjoy an unforgettable stay.

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 25 reviews

Work and relax in Equipetrol, accessible and practical

New studio apartment in the heart of Equipetrol. Ideal for 2 people looking for comfort, style and an unbeatable location. It has an equipped kitchen, a desk to work or study, fast Wi-Fi and a giant Smart TV. The building offers a swimming pool, entertainment room with views, air conditioning and automatic check-in. Perfect for digital nomads, tourists or couples who want to enjoy Santa Cruz to the fullest.

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 20 reviews

Luxury apartment opposite the Hotel Yotaú

Enjoy a unique stay in the heart of Equipetrol, the best area of the city. Located on the 13th floor, this modern apartment offers a wonderful view and a private balcony for you to relax. Fully equipped for short or long stays, designed for your maximum comfort. What's more, you can enjoy exclusive luxury social areas that will make your experience even more special.

Guest favourite
A modern living space is shown, featuring a round dining table surrounded by four chairs. A dark sofa with colorful cushions is positioned against a wall. The kitchen appliances and cabinetry are visible in the background, complemented by bright decor elements on the wall.
Flat in Santa Cruz de la Sierra
4.99 out of 5 average rating, 71 reviews

Comfortable and modern apartment

Guests can enjoy a pleasant stay in an excellent location, the apartment's design, furniture and equipment suitable for a unique experience. It has a double bed and a sofa bed, A/C in the master bedroom and living room, a bathroom with a washing machine and all the amenities, and a kitchen equipped with everything you need. Internet speed: 35 Mbps

Guest favourite
Flat in Santa Cruz de la Sierra
5.0 out of 5 average rating, 49 reviews

POX | Green Tower 15 Th Floor | Luxury and confort

Enjoy a unique experience in Bolivia's most exclusive and luxurious building: the iconic Green Tower! Let yourself be surprised with an unbeatable view, in an apartment of 80 m2, technological and luxurious. No further explanation is needed—see for yourself what it’s like to live under the purest sky in America. Rest, Enjoy, Come Back

Popular amenities for Santa Cruz holiday rentals