Holiday rentals in Santee

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Top-rated holiday rentals in Santee

Guests agree: these stays are highly rated for location, cleanliness and more.

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Guest favourite
A view from the balcony captures a serene landscape featuring a pool adjacent to Lake Marion. Lush greenery and palm trees frame the scene, while guests enjoy the pool area. The tranquil waters of the lake are visible in the background under a clear sky.
Apartment in Santee
4.96 out of 5 average rating, 93 reviews

Lovely Condo w/pool, balcony, and lakeside view!

Relax on the balcony overlooking the pool and lake Marion or go down and relax at the pool, or launch your boat at the boat ramp for the day and go fishing or cruising. There is also a myriad of golf courses near by. For dinner with a great view head over to the other side of the lake to the Lake House bar and grill for adult beverages on the lake with great food. For upscale dining Clark’s restaurant is a good choice. Bike,hike,or cook out over at Santee state park which is only 10 minutes away

Top guest favourite
The cottage is surrounded by greenery, showcasing a welcoming front porch with white railings. Two planters are placed at the entrance, and a swing is visible on the side. The entrance is accessible from a paved pathway leading to the door.
Cottage in Sumter
4.97 out of 5 average rating, 509 reviews

Restful Lakeside Getaway Cottage -Dogs allowed

This pond-side cottage is a peaceful place to relax and unwind. Sit on the enclosed porch and watch the water or enjoy the front porch swing where you can listen to the birds and frogs. We are 12 min. from downtown Sumter and 20 min from Shaw AFB. Local points of interest are Swan Lake Iris Gardens and Poinsett State Park. It is only 2 hours to Myrtle Beach and Charleston, SC & 3 hrs to the mtns. While it is conveniently located, this cottage offers a quiet place to put your feet up and rest.

Top guest favourite
A serene view of Lake Marion is captured, featuring calm waters reflecting blue skies and lush greenery. A wooden dock is visible on the left, surrounded by grass and trees, creating a tranquil natural setting.
Home in Eutawville
4.96 out of 5 average rating, 85 reviews

Heated Indoor Pool on Lake Marion with Dock

Lake Marion Lakefront on a private 2.5 wooded lot. Two houses - 4000 sq. ft. of space, plenty of room for 14! Dock to fish off of or bring your fishing boat. Heated indoor pool and Margaritaville-themed bar. Firepit, pool table, games, and dining table for 14 people. Great spot for Family Gatherings or Friends' Getaway. Golf, fishing, fruit picking, and amazing country food restaurants - 25 min drive. 5% Discount Gov. Employees :) Parties over 14 ppl ++ fees apply, details discussed prior.

Top guest favourite
A charming log home is set on a grassy lot, surrounded by trees. The façade showcases large windows that invite natural light inside. A wooden deck extends from the entrance, providing a space for outdoor seating. A paved pathway leads to the front steps.
Cabin in Vance
4.9 out of 5 average rating, 234 reviews

Log home on Lake Marion inlet w/private dock.

Relax with family and friends at this peaceful lake home. Located on an inlet one minute off the largest lake in South Carolina, Lake Marion is known for it's big fish and abundant wildlife. With your own private dock, you can boat/fish all day and leave your boat in the water for your entire stay. If you enjoy golfing, three of the states best golf courses are within minutes. This log home is centrally located between Columbia and Charleston. Restaurants, shopping, and beaches all close by.

Guest favourite
A spacious covered deck provides views of the lake through large trees, featuring two striped chaise loungers and a dining table with four chairs. The wooden flooring enhances the outdoor space, inviting relaxation and enjoyment of the serene surroundings.
Guest suite in Eutawville
4.8 out of 5 average rating, 101 reviews

Relaxing Comfortable Waterfront Family Dock Suite

Bring your family or group to this 3 bedroom 1+ bath place in the large trees with lots of room for relaxing and fun (….if you are a jeans and sweatshirt kind of person. It is not the Hilton!) TVs in each room, and 2 covered decks. Fish, or just sit out on the dock, watch the boats run by, and appreciate the lake. We rarely use the dock ourselves. 600’ from our public boat ramp with a park and small beach. Please also note that we do have cameras installed that monitor outside only.

Guest favourite
A scenic view of the lake is presented, featuring a long dock extending into the calm water. Lush greenery and palm trees frame the foreground, while a faint rainbow appears in the backdrop under a partly cloudy sky.
Home in Santee
4.96 out of 5 average rating, 170 reviews

Santee lakefront home, big water right off I-95

Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*

Top guest favourite
An outdoor deck is presented with a black wooden dining table surrounded by six chairs. A cozy seating area with red and gray cushions invites relaxation. The fenced yard is visible in the background, surrounded by trees and distant homes.
Home in Santee
4.97 out of 5 average rating, 175 reviews

Pet-Friendly Lake Marion Getaway - Just off I-95!

In the quaint lakefront town of Santee, There exists a special place. Past Main street and down a country road, nestled in a modest lakefront community, with views of the majestic Lake Marion, we've worked tirelessly to create the perfect family retreat. No matter who you call family, this home is perfect for boaters, golfers, and nature enthusiasts. Guests at the Kindred Spirits Retreat experience more than just a beautiful home, they experience the joys of purposeful travel.

Top guest favourite
Home in Santee
4.93 out of 5 average rating, 15 reviews

Sunny Santee Stay · 5BR Cityview · Lake & Golf

Brand new 2025 modern, cozy home near interstate I95, golf courses, markets, local restaurants (Cracker Barrel Old Country Store, Starbucks, etc) and Lake Marion. Santee is right in the middle distance between Miami and New York. Clean and stylish space with two 75” smart TVs, Wi-Fi, full amenities, and easy self check-in. Relax with the whole family at this new clean, quiet, safe and peaceful neighborhood. View our profile to explore more homes in the area.

Top guest favourite
A scenic view of Lake Marion is presented, featuring a wooden dock extending into the water. A picnic table is situated on the grassy shore, beneath a large tree. A flag waves gently in the breeze, adding a touch of patriotism to the serene landscape.
Home in Eutawville
4.97 out of 5 average rating, 29 reviews

Lake House at Lake Marion

Beautiful lakefront 3 Bedrooms/2 full baths with million dollar view of Lake Marion. -2 Queen beds/2 twins/1 futon -Private Dock so you can fish in “big water” -Canoe and Kayak -Firepit -Includes linens and beach towels and more! -Fully Furnished + grill and covered parking -One level open concept -75” Roku TV and WiFi -great safe neighborhood for walking and bike riding -public boat landing and county park with playground within 2 blocks.

Guest favourite
A spacious outdoor area is featured, showcasing a heated saltwater pool surrounded by lounge chairs. An umbrella provides shade, and lush greenery and trees line the background, which overlooks a serene lake. The open sky is bright with fluffy clouds.
Holiday home in Summerton
4.95 out of 5 average rating, 122 reviews

Lakefront Paradise W/Pool/hot tub/outdoor kitchen

Brand new heated saltwater pool, hot tub and outdoor kitchen area. This upgraded home is ready to host your family or large group! Enjoy breathtaking sunsets year round from your private beach directly on the big waters of Lake Marion. Spends evenings out on the dock fishing or pull your boat right up to the beach. Ping pong and bumper pool tables, fast wifi and big screen tv's make for the perfect entertaining space for large groups.

Top guest favourite
An expansive outdoor swimming pool reflects the blue sky, surrounded by well-maintained landscaping. Several lounge chairs are positioned at the pool's edge, providing a place to relax. Resort buildings are visible in the background, contributing to the inviting resort atmosphere.
Apartment in Santee
5 out of 5 average rating, 8 reviews

Lakeside Bliss: 2BR Suite at Wyndham Lake Marion

Escape to lakeside bliss at our spacious 2-bedroom, 2-bathroom resort suite located in the serene Wyndham Lake Marion. Embrace the tranquility of the picturesque surroundings as you unwind in this comfortable retreat. Book your stay at our lakeside 2BR suite and experience the perfect blend of relaxation and adventure at Wyndham Lake Marion. Create unforgettable memories in this scenic oasis.

Guest favourite
A serene lake view appears at dusk, with gentle water reflecting the sky. A wooden dock extends into the lake, accompanied by scattered benches on the shoreline. Spanish moss drapes from nearby trees, adding to the tranquil ambiance.
Home in Eutawville
4.73 out of 5 average rating, 37 reviews

Lake House for Perfect Getaway

Forget your worries in this spacious and serene space. This 3 story home offers 6 bedrooms and 4 bathrooms and large enough to house your entire family. Make it a day on the lake and catch some sun on the extended dock. Bring your boats or jet skis to enjoy the beautiful Lake Marion. When hunger hits, grill up your favorites before shooting some hoops or shooting a game of pool.

Popular amenities for Santee holiday rentals

When is the best time to visit Santee?

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Avg. price£174£180£190£189£186£207£175£207£214£217£207£213
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Frequently Asked Questions

  • Are there vacation rentals with a dedicated workspace in Santee?

    Yes! Work meets play with ease at over 10 vacation rentals in Santee featuring dedicated workspaces. Stay connected and productive in your home away from home.

  • Are there Santee vacation rentals on Airbnb with pools?

    Yes! Dive into the perfect getaway at one of over 20 vacation homes with pools in Santee, available on Airbnb. Make a splash and soak up the sun in style!

  • How much does it cost to stay in apartment rentals in Santee?

    Experience the best of Santee with our apartment rentals, starting at about $150 per day, before taxes and fees. Embrace comfort and style while staying within your budget in your home away from home.

  • Do apartment rentals in Santee have wifi?

    Absolutely! We offer over 10 apartment rentals with wifi in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Do apartment rentals in Santee have a gym?

    Absolutely! We offer over 10 apartment rentals with a gym in Santee. Enjoy a tailored experience with all the comforts you desire.

  • Are there family-friendly vacation rentals in Santee?

    Santee has more than 30 family-friendly stays. Amenities on the property may include high chairs, travel cribs, or strollers.

Quick stats about holiday rentals in Santee

  • Total holiday rentals

    Explore 30 holiday rentals in Santee

  • Nightly prices starting at

    Santee holiday rentals start at £75 per night before taxes and fees

  • Verified guest reviews

    Over 220 verified reviews to help you choose

  • Family-friendly holiday rentals

    30 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    20 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    30 of Santee holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Self check-in, Gym and BBQ grill across Santee rentals

  • 4.8 Average rating

    Santee stays are highly rated by guests – averaging 4.8 out of 5!