Apartment holiday rentals in Santee

Find and book unique apartments on Airbnb

Top-rated apartment rentals in Santee

Guests agree: these apartments are highly rated for location, cleanliness and more.

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Superhost
A wooden dock extends over the tranquil waters, framed by trees with golden leaves. Boats are visible at the floating slips, surrounded by lush greenery and a peaceful lake setting.
Flat in Santee
4.81 out of 5 average rating, 27 reviews

Dockside Villa Lake Marion

Dockside Villa on lake Marion includes a boat slip just out the back door of condo. 1 king, 1 Queen: 2 private beds and 2 baths plus pull out sofa bed in living room. Condo is fully furnished which means it will sleep up to six comfortably for a family/friends, golfing-lake adventure. Bring your boat - keep it at the dock during your stay or rent a boat next door. The amenity package includes outdoor grills, walking trails, and a boat landing. 3 world class golf courses are 3 to 5 minutes away.

Guest favourite
The exterior of a single-story, light-colored home is shown, featuring a sloped roof and front steps leading to a welcoming entryway. Lush greenery, including shrubs and trees, surrounds the house, creating a serene environment. A covered porch is visible, enhancing the outdoor space.
Flat in Orangeburg
4.82 out of 5 average rating, 28 reviews

Cozy and Charming on Raysor

Cozy and comfortable fully furnished one bedroom on quiet street, fenced back yard and off street parking. Living room, Dining room, Office, Modern Kitchen, huge deck table, chairs. WiFi, Internet, TVs, Washer & Dryer. Pet Notes: Pets have to be approved in advance of stay and pet fees will be charged Pets are welcome but there is a pet fee based on number of dogs and breed. Airbnb only charged for 1 pet, we send request for additional pet fees. Some breed are restricted by insurance company.

Top guest favourite
Flat in Moncks Corner
5 out of 5 average rating, 37 reviews

Cozy escape studio apartment

Welcome to your perfect little retreat! This cozy studio apartment is nestled in the vibrant heart of our charming small town, just steps away from local shops, cafes, parks, and everything you need for a comfortable visit (See guidebook). We are minutes from several boat ramps on the lake and river listed in the guidebook. We have plenty of space in our driveway for you to bring your boat! 🚤 This is also a perfect extended stay space for traveling nurses and respiratory therapists! 🩺

Top guest favourite
An A-frame structure is pictured, elevated on a brick foundation. Sturdy wooden stairs lead to the entrance, flanked by a deck with railings. The surrounding area is filled with tall trees, and a car is parked underneath the apartment, offering a rustic country setting.
Flat in Orangeburg
4.99 out of 5 average rating, 169 reviews

Elevated Country Apartment

Discover the charm of country-living in our cozy 1-bedroom elevated apartment, just a short drive from Orangeburg, Bamberg, and Neeses. Wake up to the sound of roosters crowing and enjoy your morning coffee with views of our picturesque homestead, or enjoy a glass of wine while watching the sun set below the majestic pines. Perfect for those seeking tranquility without sacrificing convenience, our apartment offers a fully-equipped kitchen and laundry.

Guest favourite
A serene lakeside view is captured at sunset, displaying a colorful sky with hues of orange, pink, and blue. The calm water reflects the clouds, adding to the tranquil atmosphere. A wooden dock extends into the lake, enhancing the peaceful setting.
Flat in Moncks Corner
4.82 out of 5 average rating, 17 reviews

Ophir Oasis Unit #3

Stylish, clean, and Simplistic Studio Apartment at Locklairs Landing. Unit 3 offers a perfect blend of comfort and simplicity. This studio, 1-bath is ideal for relaxing or working remotely. As well as a kitchen area fully equipped with apartment sized appliances. The property is perfect for swimming, fishing, or taking in the scenery. If you're seeking a quiet getaway or active retreat, our apartment at Locklairs Landing offers a lakeside oasis.

Flat in Summerville
5 out of 5 average rating, 3 reviews

Landing | Chic 1BD, Gym, Yoga Studio

Welcome to The Isaac in Summerville, SC. Our fully-furnished apartments feature luxurious floor plans, full kitchens, stylish furnishings, and fast WiFi. Outside your door, enjoy resort-style amenities including a swimming pool, fitness and yoga studio, and a conference room. Located just off North Creek Drive and U.S. 176, near Goose Creek and Cane Bay High School, you'll be close to local favorites like North Main Market and Azalea Square.

Superhost
A serene lakeside view is presented, featuring multiple building levels illuminated softly by exterior lights. A wooden dock extends towards the water, surrounded by lush greenery and trees, creating a peaceful atmosphere along the shoreline.
Flat in Santee

3-Bedroom Dlx @ Lake Marion Resort

You'll have a great time at this comfortable place to stay. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
The image displays a multi-story building with large windows, surrounded by autumn trees featuring vibrant orange leaves. A dock is visible in front, with a red kayak resting on the water, reflecting the calming lake environment.
Flat in Santee

Lake Marion Resort 1 Bedroom Unit

Take a break and unwind at this peaceful oasis. When a trip calls for water and the ocean won’t do, a lake retreat is just the thing. Escape the everyday at this peaceful retreat located on Lake Marion’s Chapel Branch. Explore South Carolina’s largest lake, or discover other adventures like horseback riding, mountain biking, or hiking. And if the greens are more your thing, the area is brimming with exceptional golf courses, too.

Superhost
A wooden dock extends over calm waters, with a small boat resting at the edge. Surrounding trees display vibrant autumn foliage in shades of orange and red, reflecting on the water's surface under a clear blue sky with soft clouds.
Flat in Santee

Lakeside Bliss 2BR/2BA Suite Wyndham Lake Marion

Escape to lakeside bliss at our spacious 2-bedroom, 2-bathroom resort suite located in the serene Wyndham Lake Marion. Embrace the tranquility of the picturesque surroundings as you unwind in this comfortable retreat. Book your stay at our lakeside 2BR suite and experience the perfect blend of relaxation and adventure at Wyndham Lake Marion. Create unforgettable memories in this scenic oasis.

An efficiency suite features a cozy sleeping area with a queen bed, complemented by two bedside lamps. A kitchenette with cabinets and appliances is visible, alongside a dining table with four chairs. Light wood flooring enhances the overall warm ambiance of the space.
Flat in Vance
4.67 out of 5 average rating, 9 reviews

Apartment Suite on the Lake! 2 Bedrooms!

Relax with a peaceful place to stay, right on the Lake! Fish from the dock or launch your boat, and stock up on all of your items right from our Ship's Store. Grab a great meal at our on site Restaurant or enjoy some music on a Friday or Saturday night while having a cocktail at our waterfront Tiki Bar! Cozy room on our 14 acre Resort property that will become your getaway destination!

A cozy living area is highlighted by a brown sofa, a wooden coffee table, and a small dining table. The kitchen features light cabinets and stainless steel appliances. A ceiling fan is visible above, and a television is positioned on a stand against the wall.
Flat in Summerton
4.8 out of 5 average rating, 10 reviews

Come on Down to Goat Island!

Come relax by the lake with your family or friends at this peaceful place to stay. This remodeled 1 bedroom 1 bath condo located on the beautiful Goat Island in Summerton, SC (right on Lake Marion). This quant condo features a full kitchen, living room and the upstairs bathroom and bedroom with a balcony. Boat slip rental available.

A serene view captures a community pool bordered by lush greenery and palm trees. The lake reflects a pastel sunset, enhancing the tranquil atmosphere. Chairs are arranged around the pool, inviting relaxation. A well-maintained pathway leads through the landscape towards the water's edge.
Flat in Santee
4.83 out of 5 average rating, 6 reviews

Lake and pool side vacationing

Bring the whole family to this great place with lots of room for fun. community pool just a few steps away and the biggest lake in SC right behind it and a sandy cove a couple hundred feet way. Bring or rent a boat and use the private boat landing and a dock to tie off. Condo is probably the nicest in the building!

Popular amenities for Santee apartment rentals

Quick stats about flat rentals in Santee

  • Total holiday rentals

    Explore 10 holiday rentals in Santee

  • Nightly prices starting at

    Santee holiday rentals start at £111 per night before taxes and fees

  • Family-friendly holiday rentals

    10 properties offer extra space & child-friendly amenities

  • Holiday rentals with a pool

    10 properties feature pools

  • Rentals with dedicated workspaces

    10 properties have a dedicated workspace

  • Wifi availability

    10 of Santee holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Santee rentals