
Lake house holiday rentals in Santee
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Top-rated lake house rentals in Santee
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The Heron Lake House
Lakefront Escape on Beautiful Lake Marion Wake up to stunning water views in this charming 4-bed, 2-bath lakefront home. Enjoy a large deck, screened-in porch, and newly landscaped yard—perfect for relaxing! Your stay includes 2 adult kayaks & 2 child kayaks, plus a cozy fire pit for evenings under the stars. Share meals on the deck or at the handmade farm-table inside. With your own private dock, you can easily bring your boat or water toys & make the most of Lake Marion from sunrise to sunset.

Luxury Lakefront Chalet W/Pool, Hot Tub & Beach
Bring the whole family to this gorgeous lakefront chalet with tons of guest amenities in a quiet neighborhood on Wyboo Creek. Sleeps 2 families comfortably w/ 4 large BR, 2 bathrooms, a game room, a fully equipped kitchen, living area, & screened porch. Enjoy the in ground pool w/ tanning ledge, hot tub, built-in fire pit, outdoor grilling & dining area, private sandy beach, & pier on open water. Launch your boat at the public ramp at the end of the street (.2 miles) & dock at the private pier.

Lake Murray Paradise~2 BR, 1 Bth, Kit/Living area.
Enjoy the full lake adventure with 4 kayaks included. Our property is a lake front paradise w/ about 1 acre on Lake Murray near the dam on the Lexington side of the lake. Close to Columbia, USC and Ft. Jackson. 3 Decks, 1 dock, hot tub & fire pit w/ wood. Private upper deck to the 2 Bedroom, 1 Bath suite with Open Kitchen, Living & Game Area w/ large flat screen TVs, Pool, Ping Pong & Foosball table. The entire upstairs is your private area w/ views of the lake. We offer boat tours. Fees apply.

Cozy Church Branch Cabin
A cozy lakefront cottage made by family, for family. This was our parents home away from home, their favorite getaway. Now that they're gone, we want to share what they enjoyed. Traditionally constructed lake cabin with all the comforts of home. Large partially covered deck, large pier for fishing, plenty of room to bring your boat, canoes, or kayaks. Extremely close proximity to large landings where national fishing tournaments are held on Lake Marion. Prime hunting, near great hunting clubs.

Lake Murray Family Retreat | BIG Water View Chapin
Lake Murray Family Retreat is a modest & cozy 3 bedroom, 2 bathroom home on an acre lot on Lake Murray, Chapin, SC with BIG views. We put a lot of thought into furnishing this home and had families in mind with each detail. It isn't the most updated or fanciest home on the lake, but it's one of the homiest! ★ 2 Queen beds + 3 twin beds (1 bunk + trundle) ★ 2 Full bathrooms ★ Smart TVs in the living room & primary bedroom ★ Gas fireplace ★ Firepit ★ Laundry area ★ Parking for 2 boats at dock

Hillside Haven on Lake Wateree- Entire House
Lake Wateree rental with 3 bedrooms, 2 bathrooms that will comfortably sleep 8 guests. It also has 2 sleeper sofas. It is located in Ridgeway, SC and less than 5 minutes to Buck Hill Landing. Upstairs, you will find a fully stocked kitchen, living\dining room and master bedroom. Downstairs, there is a second living area with second kitchen, bathroom and 2 bedrooms. Home includes private deep water dock. Perfect location for swimming, kayaking and fishing. Fire pit is perfect for cool nights.

Lakefront Lookout
The best panoramic views of Lake Marion! Whether you're out on the porch or indoors in our air-conditioned unit, you will not miss out on the beauty of the lake. Our updated kitchen and two full bathrooms are stocked with all the essentials. Hop on a boat, swim in the community pool, fish, walk, run, or bike the pedestrian bridge, or just hang out with your company while watching the boats go by. Please respect the fact that there is a small pet fee and we’re alerted when pets are present.

3000 sq ft lake house with views from every window
Lake Wateree 4 bedroom + bunk room with private dock and sleeps 12 comfortably. Our home has been completely renovated and is ready to enjoy! It is located in Ridgeway, SC and 20 minutes from Camden and Lugoff. Colonel Creek Landing is 4 miles away and the perfect location to launch your boat. You can dock your boat in 12 feet of water at our dock. Perfect location for fishing, kayaking and swimming. Two living spaces with smart tv's. Now you can enjoy the fire pit and outdoor shower.

Lakefront home on Lake Murray with private dock
Lakefront home on Lake Murray in Lexington, SC on over 1/2 an acre, 166 feet of waterfront with deep water, private dock, and entertainment space- perfect for an unforgettable vacation or weekend. Entire home for rent-4BR, 3 Bath +2 half baths, 2 sofa sleepers, sleeps 12. Breathtaking kitchen & large living space, perfect for the entire family. 2 single person kayaks, outdoor grill, 65 inch and 55 inch TV, washer/dryer, and fast wifi. Master suite with a lavish bathroom and soaking tub.

Downtown Columbia 3/2 - Entire House
* Entire House on a large lot with no neighbors behind for added privacy * 3 Bedrooms 2 Full Baths * 1.4 miles from PRISMA Hospital (4-minute drive) * NEWLY RENOVATED * BLACKOUT CURTAINS in all the bedrooms * 15 minutes to Fort Jackson * 7 minutes to Riverbanks Zoo * 5 minutes to the Columbia Museum of Art and Soda City Market * Split floor plan with the main bedroom on the right side of the home with on-suite * Open kitchen adjacent to the dining room overlooking the living and sunroom

Nanny’s Lake Retreat
Located in a quiet, dead end community. Enjoy the lake sounds from the spacious screened in porch. The porch has a swing, rocking chairs, and table with chairs. The den boasts a beautiful gas log fireplace and has two futons and a loveseat. The house is located in a golf cart community on a cove. Sandy beaches are just minutes away depending on the lake levels. Whether you’re looking for a vacation destination or fishing/hunting trip you will love this home. Pets require pre approval

Santee lakefront home, big water right off I-95
Lakefront home on the big water of Lake Marion. This home is on the Santee side of the lake in a quiet neighborhood, 1-2 miles from restaurants, grocery stores, golf courses and I-95. Starbucks is less than 2 miles away. *Home can accommodate 10 guests max. *Indoor hot tub is available October through March. *Only registered guests listed on the booking are authorized at the property unless prior approval has been granted. *STRICT no pet policy. *PARTIES ARE STRICTLY PROHIBITED*
Popular amenities for Santee lake house rentals
Waterfront lakehouse rentals

Lovin’ Lake Life

Riverfront Stay w/ Dock + Kayaks – Pet Friendly

Lakefront Cabin Off i95, Bells Marina & Resort

A Lake Slice of Heaven

Lake Moultrie retreat

Peaceful lake house near Columbia - sleeps 7

Almost Heaven on Lake Marion, SC

Sunrise and Sunset on the Lake
Pet-friendly lake house rentals

Jewel on the Lake

Lakefront home with boat ramp and game room

Lakefront w/ dock at Mill Creek

Cutest Cottage on the Lake

Lake Marion Cottage

Fisherman's Dream at Low Falls Landing-Lake Marion

Large Lakefront Home w/360 view, beaches, & dock

Luxe Lake Marion Oasis with Pool/Hot Tub/Dock
Private lake house rentals

Beautiful 3-Bedroom House

Santee/Lizzie's Creek Lakefront

Cozy Little Nook

Palms in Paradise 2 Docks & Steps into Lake Murray

Cove Cottage

Lowcountry Cottage

Be "On Lake Time" with Waterfront and Private Dock

Lake Marion Beauty w/ 5br/3ba
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- Rentals with a washing machine and dryer Santee
- Family-friendly rentals Santee
- Rentals with lake access Santee
- Rentals with pools Santee
- Pet-friendly rentals Santee
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- Lakehouse rentals South Carolina
- Lakehouse rentals United States
- Riverbanks Zoo and Garden
- Middleton Place
- Congaree National Park
- South Carolina State House
- Columbia Museum of Art
- South Carolina State Museum
- Whirlin' Waters Adventure Waterpark
- University of South Carolina
- Colonial Life Arena
- Magnolia Plantation & Gardens
- North Charleston Coliseum & Performing Arts Center
- Columbia Metropolitan Convention Center
- Edventure
- Riverfront Park
- West Columbia Riverwalk Park and Amphitheater
- Charleston Southern University
- Cypress Gardens
- Soda City Market
- Williams Brice Stadium
- Sesquicentennial State Park
- Wannamaker County Park




