
House holiday rentals in Upstate South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in Upstate South Carolina
Guests agree: these houses are highly rated for location, cleanliness and more.

River Love ❤@ The Barn *Highlands Trout Fishing
This romantic retreat on the CULLASAJA RIVER will have you swooning for your love and wanting to stay longer. Nestled in a picturesque valley at higher elevations with views of the lower gorge and the Cullasaja river rapids as your playground, the open floor plan and abundant windows feel like treehouse. Romantic is just the beginning as you sleep with views of the moon and stars over your bed in 1 of 2 Master Bedrooms. Or choose the 2nd enormous suite downstairs for more views of the river.

Atrium House - Spa Retreat
Come unwind and breathe at our couples mountain spa retreat. Atrium House has been designed to feel open to the lovely mountain surroundings yet let you relax in privacy. Our outdoor therapy hot tub, indoor/outdoor gas fireplace, and spacious two-person, walk-in shower make for a getaway so tranquil, you may never make it in to nearby Asheville! We're out in the country but just over a 15-minute drive from downtown Asheville, Biltmore, Hendersonville, Asheville Airport, and dozens of breweries.

NEW mountain cottage between Dupont and Pisgah!!
Getaway and enjoy this New fully furnished cottage style home complete with new queen beds, hardwood floors on a beautiful private .50 acre lot. Listen to the small waterfall and catch a peak of the local deer sipping from our backyard stream as you enjoy your morning cup of joe on the balcony. Then take a ride into downtown Brevard to hit the local eats and shops. Pisgah Forest is centrally located to Dupont State Forest and Pisgah National Forest, Downtown Brevard and a variety of breweries.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Grace Mountain Cottage-Mtn views /Peaceful+Private
Kick back and relax in this calm, stylish space. Escape to serenity at our mountain top cottage, 20 min to Asheville. Embrace panoramic mountain views from every corner of this charming retreat. Unwind by the outdoor firepit, roasting s'mores under the starlit sky. Enjoy al fresco dining with a backdrop of breathtaking sunsets. This cozy cottage sleeps 4, perfect for a family or friends seeking tranquility and nature's embrace. Experience the essence of mountain living in comfort and style!

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Franklin A-Frame with Hot Tub and Mountain Views
Escape to this stylish mountain retreat featuring 3 bedrooms and 2 bathrooms. Relax on the spacious deck or soak in the private hot tub while taking in breathtaking views of the Blue Ridge Mountains. Stay connected with high-speed internet, perfect for work or streaming during your stay. Ideally located for adventure: just 8 minutes to Downtown Franklin, 30 minutes to Highlands, 1 hour to Asheville, and close to countless hiking trails, waterfalls, scenic drives, and more!

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Walk-to-Downtown Retreat | Creekside + Hot Tub
Perfect get away, this 820-sq-ft creekside cabin blends 1950s charm with modern comforts—two queen bedrooms, a bright kitchen, and a relaxed living room. Step onto the back porch or creekside patio for slow mornings and sunset chats, then wander 5 minutes to downtown Clayton for dinner, craft drinks, and dessert. Afterward, slip into the hot tub under the stars. Trails, waterfalls, whitewater, and Black Rock Mountain vistas are minutes away.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
Popular amenities for house rentals in Upstate South Carolina
House rentals with a pool

Pet-Friendly 4BR: Pool, Screen Porch, Fenced Yard

Keowee Key Luxury Condo - Stunning Views!

Estate-Like Retreat/ Walk to Town /Hot Tub & Pool

Wonderful mountain cottage with amazing view!

Shalom House with Pool near DT Greer SC

NEW - Heated Pool - Hot Tub - Game Room - Sauna -

Spacious 3 BR house with private backyard.

Near Downtown Greenville + Swamp Rabbit Trail
Weekly house rentals

Private Luxury Resort Greenville | Spa, Pool More

Private Luxe Romantic Mountain View Getaway

KargoHaus - Dog Park - Unique Getaway Near Helen

Lakefront Mid-Century Dream Home / 3 mi to Clemson

Welcome to River House

Mountain Villa 15min from Downtown Greenville

100 acre peaceful Retreat, Creek+Views+Hiking

Mountaintop A-Frame Trails, Tub & Firepit Sleeps 8
Private house rentals

Modern Cottage in the Woods w/ Hot Tub & Firepit

Mountain Rest Lake Becky Retreat

Huge Views, Outdoor Tub, Fire Pit, Close to Town!

Heart of Downtown Fountain Inn

Mountain Home | Backyard Waterfall | Sleeps 10+

Riverfront Escape w Deck, Porch and Fenced Yard

Whitewater Lake Front Cottage

Sunset Cottage -Waterfront with Kayaks
Destinations to explore
- Augusta Holiday rentals
- Western North Carolina Holiday rentals
- Atlanta Holiday rentals
- Nashville Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Savannah Holiday rentals
- Hilton Head Island Holiday rentals
- Cape Fear River Holiday rentals
- Pigeon Forge Holiday rentals
- Townhouse rentals Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Rentals with a firepit Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Villa rentals Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Barn rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- Flat rentals Upstate South Carolina
- Rentals with a cinema Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Tent rentals Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Hotel rooms Upstate South Carolina
- Holiday home rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Boutique hotels Upstate South Carolina
- Rentals with an accessible-height toilet Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Farm stay rentals Upstate South Carolina
- Motorhome rentals Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- Resort rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Guest house rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- The North Carolina Arboretum
- Gorges State Park
- Chimney Rock State Park
- Table Rock State Park
- Clemson University
- Lake Lure Beach and Water Park
- Tryon International Equestrian Center
- Jump Off Rock
- Bon Secours Wellness Arena
- Saint Paul Mountain Vineyards
- Burntshirt Vineyards
- Carl Sandburg Home National Historic Site
- Devils Fork State Park
- Jones Gap State Park
- Fred W Symmes Chapel
- Overmountain Vineyards
- Falls Park On The Reedy
- Peace Center
- DuPont State Forest
- Paris Mountain State Park
- Looking Glass Falls
- Furman University
- Fluor Field at the West End
- Things to do Upstate South Carolina
- Things to do South Carolina
- Art and culture South Carolina
- Sports activities South Carolina
- Nature and outdoors South Carolina
- Sightseeing South Carolina
- Entertainment South Carolina
- Tours South Carolina
- Food and drink South Carolina
- Things to do United States
- Wellness United States
- Food and drink United States
- Entertainment United States
- Sightseeing United States
- Sports activities United States
- Tours United States
- Nature and outdoors United States
- Art and culture United States




