House holiday rentals in Upstate South Carolina

4.98 out of 5 average rating, 212 reviews

Home in Taylors

Vintage home near downtown Greenville.

Cozy home with vintage look. Be in downtown Greenville or Paris Mt. State Park in under ten minutes. Close to shopping and the state Farmer's Market is a mile away. Acre yard gives spacious feeling. A complimentary Power Point of South Carolina and local history, culture, events, and business is available to help introduce you to one of the country's best kept secrets. Cut flowers and help yourself to our organic garden for use during your stay (seasonally). Small RV parking but no hook ups.

4.99 out of 5 average rating, 177 reviews

Modern Designer Getaway Near Downtown Greenville

Welcome to your Greenville getaway! Minutes from downtown, GetawayGVL is a designer 1950s midcentury modern ranch that offers the conveniences of a hotel with the comforts of home. This bright and airy 3BR, 1.5BA tropical oasis boasts a stunning outdoor space with yard games for entertaining, a dedicated desk for working, and a designer den for relaxing. You're only minutes away from a walk on the Swamp Rabbit Trail, dinner by the Reedy River, or a concert at The Well! Book your getaway today!

5 out of 5 average rating, 126 reviews

Home in Travelers Rest

Modern Wooded Retreat

Come enjoy this modern, 1.6 acre retreat! Relax with the whole family in a place you'll never want to leave. Located 5 min. to downtown TR and less than 20 min to downtown Greenville! Roast marshmallows by the firepit, play yard jenga, connect 4 and cornhole in the fully fenced, dog friendly back yard. Close to the swamp rabbit trail, and centrally located to lakes, hiking, fishing and exciting nightlife. Let us host you, while you explore everything Greenville and Travelers Rest have to offer.

4.94 out of 5 average rating, 281 reviews

Home in Westminster

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Paths for long walks. Architect James Fox designed this cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

4.98 out of 5 average rating, 103 reviews

Greenville GEM Luxurious Retreat in Prime Location

Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

4.97 out of 5 average rating, 226 reviews

Spectacular home 1 mile from Main St Greenville!

Enjoy your stay in this charming up to date house 1 mile from Main St Greenville! Take a walk through the Historic Pinckney district on your way to Greenville’s museums, restaurants, theaters, and stunning Reedy River Falls Park. Easy access to the Swamp Rabbit biking and walking trail, and just 4 blocks from the upcoming Unity Park. House is located on quiet residential street with private driveway. Relax on rocking chairs on front porch or around a portable fire pit in large backyard.

4.99 out of 5 average rating, 331 reviews

Home in Lake Toxaway

Cabin I Private hiking trails | Hot Tub I Sauna

Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

5 out of 5 average rating, 161 reviews

Home in Greenwood

The Little White House

Kick back and relax in our newly built guest house. We have put a lot of thought and effort into our space for you to have a comfortable stay. Enjoy a country living feel while being just minutes from shopping, restaurants, and the hospital. The host also live behind the property should you need anything. No pets. No smoking. This space is for paying guest only. No parties! We also have a 2nd listing in Greenwood- The Cottage @ Hill & Dale. *OWNER IS A LICENSED REAL ESTATE AGENT.

4.99 out of 5 average rating, 268 reviews

Home in Candler

Million Dollar View’s | Chef Kitchen | Luxury bath

Cloud 9 isn’t just a place to stay — it’s a place to feel. Elegant. Refined. Rooted in nature. Thoughtfully designed and tucked into the mountains, this soulful retreat offers stillness, beauty, and intention in every detail. It doesn’t compete with the land — it whispers into it. Here, quiet becomes the ultimate amenity. A place that feels like home — and a dream — all at once. Come experience the kind of calm that stays with you. Book your stay in the clouds!

4.99 out of 5 average rating, 211 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

4.97 out of 5 average rating, 239 reviews

Home in Simpsonville

Willow Oak Retreat // Comfy beds & Large backyard!

Welcome to Willow Oak Retreat! We cant wait to host you! - Private deck with grill and eating area - Fully equipped kitchen with tea, coffee and snacks - Safe and quiet neighborhood - 1 mile to all of downtown Simpsonville's restaurants and shops - 1 mile to huge park including playground, tennis, basketball and farmers market. - Short 20 minute drive to downtown Greenville - Perfect for families and those traveling for work!