House holiday rentals in Upstate South Carolina

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Top-rated house rentals in Upstate South Carolina

Guests agree: these houses are highly rated for location, cleanliness and more.

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Guest favourite

Home in Iva

4.98 out of 5 average rating, 350 reviews

Country Cottage ~ Farm Animals!

Step away from your hustle as you enjoy this cozy, quiet setting in the country. We offer a small kitchen, microwave, toaster, a Keurig, refrigerator, and two-burner stove. You will find a comfy dining/sitting room area. Meander around outside, relax on the porch, or visit our farm animal pets. 20 minutes from Historic Abbeville. Greenwood or Anderson in 30 min. Greenville approx 1 hr. 5 miles from Erskine College 15 min to the famous Diamond Hill Mine! Heyward Manor wedding venue: 18 miles

Guest favourite

Home in Taylors

4.99 out of 5 average rating, 138 reviews

Vintage home near downtown Greenville.

Cozy home with vintage look. Be in downtown Greenville or Paris Mt. State Park in under ten minutes. Close to shopping and the state Farmer's Market is a mile away. Acre yard gives spacious feeling. A complimentary Power Point of South Carolina and local history, culture, events, and business is available to help introduce you to one of the country's best kept secrets. Cut flowers and help yourself to our organic garden for use during your stay (seasonally). Small RV parking but no hook ups.

Guest favourite

Home in Greenville

4.97 out of 5 average rating, 154 reviews

A Tranquil Place (near downtown Greenville)

A Tranquil Space is conveniently located close to Downtown Greenville. The large suite includes the bedroom, living area, kitchenette (fridge/freezer/convection oven), bathroom, and study/eating area. It is newly renovated area on the end of my home with a private entrance. The space is welcoming and inviting...a perfect space to get away from the hustle. Although minutes from Downtown, the suite feels like you're in the mountains with a private back yard and many trees. Enjoy your stay!

Guest favourite

Home in Hartwell

4.84 out of 5 average rating, 368 reviews

3 little Care Bear bungalow

Come and experience a little getaway on Lake Hartwell. This is a cute little house, perfect for families or just getting away from the hustle and bustle of Atlanta or Charlotte. There is fishing and you can go swimming in the cove. there's is plenty of parking available on my driveway for your boat SUV or other vehicles. Walmart and Ingles is about 8.2 miles from the house. drive into the city of Hartwell and experience some of the local dining. I left some brochures of my favorite restaurants.

Guest favourite

Home in Iva

4.98 out of 5 average rating, 158 reviews

Moonshine Bay

Your home away from home on South Carolina’s hidden gem, Lake Secession. Private wooded drive opens up to phenomenal lake view with shallow water entrance. Great for water sports, swimming, fishing and relaxation. If swimming isn’t for you, many beautiful reasonably priced golf courses are near by. Only 10 miles from Anderson & 36 miles to Clemson Stadium. Pull your boat to the dock or just enjoy some of our non-motorized lake toys. You’ll love it so much you want to come back year after year!

Guest favourite

Home in Pendleton

4.89 out of 5 average rating, 131 reviews

Comfort & Convenience Close to Campus

The perfect blend of modern charm and full comfort & convenience just minutes from Clemson, The Pendleton Square and HWY access. You will be sure to have everything you need for your visit. Comfortably sized bedrooms with queen size beds. Spacious living area with cable TV & Netflix. Bright and open kitchen and dining fully equipped for all your cooking needs. Whether you're traveling alone for a little peace & quiet, with friends, or with family... we hope you enjoy your time here!

Guest favourite

Home in Lake Toxaway

4.99 out of 5 average rating, 259 reviews

Treehouse with a Hot Tub, Hiking Trails & View

Perfect Mountain getaway. A place to unplug, reconnect & recharge in our fully stocked little treehouse in the woods. Enjoy swinging on the porch while watching the sunset over the mountainous view or roast marshmallows at the outdoor fire pit. The home a uniquely crafted Cabin. Prive Hiking Trails on property, outdoor pizza oven, Hot tub under the stars, cold plunge & sauna. This little cabin has so much to offer 25 minutes to Cashiers 25 minutes to Brevard 1 hour from Asheville

Guest favourite

Home in Easley

4.9 out of 5 average rating, 276 reviews

“Lake House Paradise” Waterfront Oasis

“Lake Paradise” is exquisitely furnished with 2 bedrooms and 1 and a half baths. Your Master Suite has its own screened in porch with private lake access. Wake up from your master suite to views from your bed of the water. Your en suite Master Bathroom has a large luxury marble shower. You will spend many hours of relaxation and peace in the most desirable location in the southeast. Visit Greenville SC's downtown just 15 minutes away. Clemson football Stadium is 20 miles away.

Guest favourite

Home in Greenville

4.99 out of 5 average rating, 131 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Guest favourite

Home in Anderson

4.99 out of 5 average rating, 178 reviews

Lake Escape

This is the perfect lake house for your next family vacation, Clemson football game, or just a long weekend at the lake! Enjoy full access to Lake Hartwell with a private dock and swimming area. The house is located just 20 minutes from both Clemson and Anderson and also just 5 minutes from Portman Marina. Kayaks do not come included with the house but can be rented if inquired about ahead of time. Come enjoy some nature, relaxation, and fun at the Lake Escape!

Guest favourite

Home in Abbeville

4.99 out of 5 average rating, 227 reviews

**Oak View**Peaceful**8 min to Erskine

If you are looking for a place to kick your shoes off and relax this is it! Whether its on the comfortable couches or on your own private deck watching the sunset and the cows grazing peacefully in the pasture. Everything has been updated from the new floors, paint, and new appliances and it's sparkling clean. the big bedroom has a king size bed and plenty of space to unpack and relax.

Guest favourite

Home in Pendleton

4.99 out of 5 average rating, 131 reviews

3 BR/2BA Cottage in Pendleton - 9 Miles to Clemson

For your next getaway, escape to our Pendleton Cottage. Located just 9 miles from Clemson's Memorial Stadium, you will find everything you need in our home away from home, including a full kitchen, a living room with a 65" TV, 3 bedrooms, each with its own 43" TV, 2 bathrooms, a huge fully fenced back yard, a full laundry room and so much more.