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House holiday rentals in Upstate South Carolina

Find and book unique houses on Airbnb

Top-rated house rentals in Upstate South Carolina

Guests agree: these houses are highly rated for location, cleanliness and more.

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Top guest favourite
A charming large barn-style home is set against a backdrop of trees and a hillside. The structure features a wooden facade and a roof covered with metal. The surrounding landscape includes a grassy lawn and decorative wooden fencing.
Home in Highlands
4.97 out of 5 average rating, 212 reviews

River Love ❤@ The Barn *Highlands Trout Fishing

This romantic retreat on the CULLASAJA RIVER will have you swooning for your love and wanting to stay longer. Nestled in a picturesque valley at higher elevations with views of the lower gorge and the Cullasaja river rapids as your playground, the open floor plan and abundant windows feel like treehouse. Romantic is just the beginning as you sleep with views of the moon and stars over your bed in 1 of 2 Master Bedrooms. Or choose the 2nd enormous suite downstairs for more views of the river.

Top guest favourite
A gravel driveway winds through lush greenery leading to a contemporary mountain home. The structure features large windows that offer a glimpse of the inviting interior. Surrounding trees enhance the private, serene atmosphere of the location.
Home in Fairview
4.97 out of 5 average rating, 346 reviews

Modern Mtn Home - Hot Tub + Firepit + Luxury2

Asheville is Calling You Back – Be Part of the Comeback Asheville is open and more vibrant, resilient, and determined than ever — recently named a top 2025 destination by Forbes Travel Guide and The New York Times. Our Luxury-Romantic Contemporary mountain home is nestled in Fairview, NC. Only about 14 miles (approximately 22 minute) drive into downtown Asheville. Surrounded by the sounds of nature, complete with outdoor private hot tub + gas fire pit + and all the comforts of mountain life.

Top guest favourite
A screened porch is highlighted, featuring comfortable wooden seating with light cushions and a matching table. Natural light is allowed through large windows and a skylight, providing a view of the surrounding greenery. A small potted plant decorates the table, enhancing the relaxing atmosphere.
Home in Greenville
4.96 out of 5 average rating, 154 reviews

The Greenville Nest - Retreat & Relaxation Home

This beautifully one-level home offers 3 queen beds and 2 baths, accommodating up to 6 guests. Centrally located in a peaceful neighborhood. 8-minute drive to GSP airport, 15-minute drive to downtown Greenville, minutes from I-85/385, and minutes from Woodruff and Pelham Rd. You'll appreciate the easy access to food delivery and restaurants. Enjoy a stylish Experience for entertaining, working, and relaxing with high-speed Wi-Fi. Quiet and safe with an enjoyable private screened porch and Grill.

Top guest favourite
A charming cottage entrance is framed by natural stone and wood features. A path of stepping stones leads to a spacious outdoor area, where several Adirondack chairs are arranged, offering unobstructed views of the surrounding mountains and lush greenery.
Home in Candler
4.97 out of 5 average rating, 120 reviews

Grace Mountain Cottage-Mtn views /Peaceful+Private

Kick back and relax in this calm, stylish space. Escape to serenity at our mountain top cottage, 20 min to Asheville. Embrace panoramic mountain views from every corner of this charming retreat. Unwind by the outdoor firepit, roasting s'mores under the starlit sky. Enjoy al fresco dining with a backdrop of breathtaking sunsets. This cozy cottage sleeps 4, perfect for a family or friends seeking tranquility and nature's embrace. Experience the essence of mountain living in comfort and style!

Top guest favourite
Home in Greenville
4.99 out of 5 average rating, 106 reviews

Mountain Top Getaway w/ Hot Tub & Sauna!

Escape to an exclusive luxury log home with Hot Tub on prestigious Paris Mountain—great for romantic escapes but large enough for gatherings with friends and family. Enjoy: • Sunrise mountain views from the Hot Tub • Steam shower, sauna, soaking tub inside • European shower room with soaking tub • Indoor fireplaces • Dual balconies for stargazing & wine nights • Cozy bedrooms after days of hiking or exploring nearby Greenville & Travelers Rest Surrounded by million-dollar homes and views.

Top guest favourite
Home in Lake Toxaway
4.99 out of 5 average rating, 369 reviews

Cabin I Private hiking trails | Hot Tub I Sauna

Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Top guest favourite
A spacious living area is illuminated by natural light, featuring large windows with scenic mountain views. Soft, neutral-colored seating is arranged for comfort, including a cozy sectional sofa and armchairs. Decorative curtains frame the windows, enhancing the inviting atmosphere.
Home in Saluda
4.99 out of 5 average rating, 138 reviews

Orchard Hill Vintage Cottage

Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Guest favourite
Home in Westminster
4.94 out of 5 average rating, 296 reviews

Waterfall Views, Lake Hartwell, Highland Architect

Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Top guest favourite
The exterior of a modern mountain retreat is highlighted, featuring dark blue wooden siding and vibrant orange shutters. A gravel pathway leads to the entrance, with natural stone accents surrounding the area. Trees provide a lush backdrop, showcasing the serene wooded setting.
Home in Demorest
4.98 out of 5 average rating, 135 reviews

The Ridge: A Ga. Mtn. Hideaway

The Ridge is a tranquil retreat in Northeast Georgia. Enjoy a modern living space, fully equipped kitchen, private hot tub, and outdoor fire pit. Also featuring eco-conscious amenities, such as an EV charger and recycling services. A four minute drive from Piedmont University and downtown Demorest, The Ridge offers the perfect blend of nature (but not wilderness) and convenience. Experience the beauty of the Northeast Georgia Mountains in comfort and style. Humans only, no pets.

Top guest favourite
The treehouse structure features a distinctive A-frame design with large glass paneling allowing for abundant natural light. Surrounded by trees, an outdoor deck with seating complements the lush woodland setting. The rooftop deck above adds to the unique architectural appeal.
Home in Greenville
4.99 out of 5 average rating, 261 reviews

Cozy Treehouse

Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

Top guest favourite
A charming cottage is surrounded by lush greenery and tall trees, featuring a welcoming front porch with seating. The exterior is clad in grey siding and highlights stylish architectural design elements. A gravel driveway leads up to the house, emphasizing its peaceful and private setting.
Home in Seneca
5 out of 5 average rating, 129 reviews

The Cottage

Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.

Top guest favourite
An Airstream is positioned near a wooden deck featuring a hot tub, surrounded by lush greenery and trees. The deck is equipped with cozy seating and a firepit, creating an inviting outdoor space for relaxation.
Home in Pisgah Forest
5 out of 5 average rating, 194 reviews

Airstream w/ Bathtub, River, & Hot Tub

-Near restaurants, breweries, hiking, waterfalls -Private deck w/ hot tub, firepit, grill -Latte maker, soaker tub, rain showerhead -Heat, Air, Wifi, king bed, luxury linens -Dimmable lighting, peaceful location Come hiking, visit local restaurants, and stay at Royal Fern at Roamly Getaways in Brevard NC! This unique Airstream experience will leave you rested and revitalized. Our area is open and was safe from Hurricane Helene!

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