
House holiday rentals in Upstate South Carolina
Find and book unique houses on Airbnb
Top-rated house rentals in Upstate South Carolina
Guests agree: these houses are highly rated for location, cleanliness and more.

River Love ❤@ The Barn *Highlands Trout Fishing
This romantic retreat on the CULLASAJA RIVER will have you swooning for your love and wanting to stay longer. Nestled in a picturesque valley at higher elevations with views of the lower gorge and the Cullasaja river rapids as your playground, the open floor plan and abundant windows feel like treehouse. Romantic is just the beginning as you sleep with views of the moon and stars over your bed in 1 of 2 Master Bedrooms. Or choose the 2nd enormous suite downstairs for more views of the river.

Modern Mtn Home - Hot Tub + Firepit + Luxury2
Asheville is Calling You Back – Be Part of the Comeback Asheville is open and more vibrant, resilient, and determined than ever — recently named a top 2025 destination by Forbes Travel Guide and The New York Times. Our Luxury-Romantic Contemporary mountain home is nestled in Fairview, NC. Only about 14 miles (approximately 22 minute) drive into downtown Asheville. Surrounded by the sounds of nature, complete with outdoor private hot tub + gas fire pit + and all the comforts of mountain life.

Atrium House - Spa Retreat
Come unwind and breathe at our couples mountain spa retreat. Atrium House has been designed to feel open to the lovely mountain surroundings yet let you relax in privacy. Our outdoor therapy hot tub, indoor/outdoor gas fireplace, and spacious two-person, walk-in shower make for a getaway so tranquil, you may never make it in to nearby Asheville! We're out in the country but just over a 15-minute drive from downtown Asheville, Biltmore, Hendersonville, Asheville Airport, and dozens of breweries.

Modern Lake Vibes – Kayaks, Dock & Fireplace
The perfect home for lake lovers and college football fans. Located just ~5 minutes away from Clemson and Death Valley, the newly renovated lakefront cottage will be the perfect stay for you, your family, and friends. With an outdoor fire pit, amazing views, boat dock, kayaks, and a modern kitchen, this retreat has all the amenities you're looking for inside and out! Whether you spend your time relaxing at the house, cheering on the Tigers, or fishing the lake, the Hideaway is sure to please.

Greenville GEM Luxurious Retreat in Prime Location
Beautifully renovated 3 beds, 2 baths haven! This gem is a tranquil & stylish retreat, blending modern & cozy charm. Spacious bedrooms, each with plush bedding and storage. Two Bathrooms with soaking tub and a spacious walk-in shower. Cozy living room with a fireplace, TV, and comfy seating. Fully equipped kitchen, Wi-Fi, Private deck and gazebo, fenced yard. Close to the city's best attractions, dining, and entertainment options. This is the perfect home base for your Greenville adventures.

Grace Mountain Cottage-Mtn views /Peaceful+Private
Kick back and relax in this calm, stylish space. Escape to serenity at our mountain top cottage, 20 min to Asheville. Embrace panoramic mountain views from every corner of this charming retreat. Unwind by the outdoor firepit, roasting s'mores under the starlit sky. Enjoy al fresco dining with a backdrop of breathtaking sunsets. This cozy cottage sleeps 4, perfect for a family or friends seeking tranquility and nature's embrace. Experience the essence of mountain living in comfort and style!

Beautiful Lake Front Cottage on Lake Greenwood
Come enjoy the beauty of Lake Greenwood from this custom fully renovated gem. Whether you prefer to float in the cove or boat the lake this place is a perfect, family friendly get away. 3 bedrooms, 2 bathrooms, open floor plan with family room leading to a custom kitchen and adorable sitting nook. Massive deck offers outdoor dining and plenty of space to relax. An easy walk to the brand new dock that is big enough for your boat and plenty of water fun. Come stay and enjoy our lake getaway!

Cabin I Private hiking trails | Hot Tub I Sauna
Welcome to your private mountain escape in Lake Toxaway, NC! This 1-bedroom, 2-bathroom cabin is a one-of-a-kind retreat, offering breathtaking sunset views, a peaceful wooded setting, and unique architectural details. Unwind in the hot tub under the stars, relax in the sauna, challenge your partner to air hockey, or cozy up by the fire pit—all while enjoying the beauty of nature. Plus, enjoy exclusive access to 3 miles of private hiking trails, perfect for exploring the great outdoors!

Orchard Hill Vintage Cottage
Come enjoy this magnificent view in Saluda! Relax in the swings or sit on the porch and enjoy the peacefulness. The fire pit under the stars is so Saludacrous! Our cozy cottage is just steps from Judds Peak and 2 miles from downtown, where there is always food and fun! The Gorge Zipline is located in our quaint little town and the Green River has hiking, tubing, kayaking, white water rafting, rock climbing! The towns of Hendersonville, Flat Rock and Asheville are just minutes away.

Waterfall Views, Lake Hartwell, Highland Architect
Come and enjoy nature with 100+ acres to roam. Architect James Fox designed this cantilevered cliffside home overlooking a beautiful waterfall. Feel like you are in the trees, in an area much as it was when inhabited by Cherokee Indians. Stream feeds into Lake Hartwell. In the summer months on the weekends and holidays kayaks, jet skis and small boats visit the falls. This property is in the foothills of the Appalachian Mountains. Please respect our pet policy, only service animals.

Cozy Treehouse
Situated at the back of a wooded 2 acre lot, only 10 minutes from downtown Greenville, this is a little oasis in the city! While most treehouses take you on a "roughing it" adventure, Cozy Treehouse is the glamping version of treehouses, boasting 9' ceilings, 1.5 baths, 3 LED TV's and many outdoor living options. If you are looking for a unique getaway just minutes from one of the top growing cities in the south, Cozy Treehouse is the perfect destination for you.

The Cottage
Relax, recharge, and enjoy the quiet. Unwind on the front porch as the sun sets and nature comes alive with the peaceful sounds of evening. Spend time by the pond and cast a line for a simple, relaxing escape (fishing poles not provided). Private and serene, yet just 5 minutes to Walmart and Oconee Memorial Hospital—and only 13 miles to Clemson. The perfect blend of tranquility and convenience. Minimum age to book is 25 years of age.
Popular amenities for house rentals in Upstate South Carolina
House rentals with a pool

Keowee Key Luxury Condo - Stunning Views!

Estate-Like Retreat/ Walk to Town /Hot Tub & Pool

Pool Gameroom Hot Tub Family Fun Getaway

BICYCLE HAVEN

Shalom House with Pool near DT Greer SC

Spacious 3 BR house with private backyard.

Pool, Game Room, Hot Tub, Golf!

Say hello to Splash Home
Weekly house rentals

900' of lake front property - 20 min from Clemson

The Mountain House

Harbor Light Lake House w/ Hot Tub

Altamont Rest-Top of the Mtn Luxury Adult Retreat

5 minutes to town! Emerald Ferns Cottage

North House - Charming home, walk to AU & AnMed

Valhalla: Cliff-Edge Suite · Forest Views · Tub

Sunlight Chalet, Ultimate Highlands Destination
Private house rentals

Modern Cottage in the Woods w/Hot Tub & Firepit

Palmetto Trailside Retreat

Welcome to River House

Mountain Home|Backyard Waterfall|Sleeps 10+|pets+

Little Bear Lodge

Beautiful, secluded, nestled in the woods+sauna!

Tiny Home-Hot Tub-Epic Views -Fragrance Free

Quiet & Cozy in Traveler's Rest
Destinations to explore
- Western North Carolina Holiday rentals
- Atlanta Holiday rentals
- Nashville Holiday rentals
- Myrtle Beach Holiday rentals
- Charleston Holiday rentals
- Gatlinburg Holiday rentals
- Charlotte Holiday rentals
- Hilton Head Island Holiday rentals
- Savannah Holiday rentals
- Cape Fear River Holiday rentals
- Pigeon Forge Holiday rentals
- North Myrtle Beach Holiday rentals
- Tent rentals Upstate South Carolina
- Villa rentals Upstate South Carolina
- Townhouse rentals Upstate South Carolina
- Rentals with beach access Upstate South Carolina
- Nature eco lodge rentals Upstate South Carolina
- Guest house rentals Upstate South Carolina
- Rentals with an EV charger Upstate South Carolina
- Rentals with a sauna Upstate South Carolina
- Rentals with a kayak Upstate South Carolina
- Resort rentals Upstate South Carolina
- Rentals with a hot tub Upstate South Carolina
- Barn rentals Upstate South Carolina
- Rentals with a fireplace Upstate South Carolina
- Rentals with a firepit Upstate South Carolina
- Rentals with pools Upstate South Carolina
- Farm stay rentals Upstate South Carolina
- Motorhome rentals Upstate South Carolina
- Rentals with a cinema Upstate South Carolina
- Rentals with an accessible-height toilet Upstate South Carolina
- Rentals with outdoor seating Upstate South Carolina
- Private suite rentals Upstate South Carolina
- Waterfront rentals Upstate South Carolina
- Serviced apartment rentals Upstate South Carolina
- Rentals with a patio Upstate South Carolina
- Beachfront rentals Upstate South Carolina
- Rentals with breakfast Upstate South Carolina
- Boutique hotels Upstate South Carolina
- Holiday home rentals Upstate South Carolina
- Pet-friendly rentals Upstate South Carolina
- Campsite rentals Upstate South Carolina
- Tiny house rentals Upstate South Carolina
- Chalet rentals Upstate South Carolina
- Family-friendly rentals Upstate South Carolina
- Smoking-friendly rentals Upstate South Carolina
- Hotel rooms Upstate South Carolina
- Cabin rentals Upstate South Carolina
- Loft rentals Upstate South Carolina
- Treehouse rentals Upstate South Carolina
- Rentals with lake access Upstate South Carolina
- Fitness-friendly rentals Upstate South Carolina
- Rentals with a washing machine and dryer Upstate South Carolina
- Cottage rentals Upstate South Carolina
- Apartment rentals Upstate South Carolina
- Flat rentals Upstate South Carolina
- Bed and breakfasts Upstate South Carolina
- House rentals South Carolina
- House rentals United States
- Blue Ridge Parkway
- Clemson University
- The North Carolina Arboretum
- Chimney Rock State Park
- Gorges State Park
- Lake Lure Beach and Water Park
- Table Rock State Park
- Tryon International Equestrian Center
- Jump Off Rock
- Ski Sapphire Valley
- Saint Paul Mountain Vineyards
- Bon Secours Wellness Arena
- Burntshirt Vineyards
- Fluor Field at the West End
- DuPont State Forest
- Devils Fork State Park
- Peace Center
- Carl Sandburg Home National Historic Site
- Jones Gap State Park
- Overmountain Vineyards
- Looking Glass Falls
- Falls Park On The Reedy
- Fred W Symmes Chapel
- Whitewater Falls
- Things to do Upstate South Carolina
- Things to do South Carolina
- Food and drink South Carolina
- Tours South Carolina
- Art and culture South Carolina
- Nature and outdoors South Carolina
- Sightseeing South Carolina
- Sports activities South Carolina
- Entertainment South Carolina
- Things to do United States
- Tours United States
- Entertainment United States
- Sports activities United States
- Nature and outdoors United States
- Wellness United States
- Art and culture United States
- Sightseeing United States
- Food and drink United States





