
Family-friendly holiday rentals in Panama City
Find and book unique family-friendly homes on Airbnb
Top-rated family-friendly rentals in Panama City
Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

In the heart of Casco, refurbished and with parking
Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Apto 4 min from Tocumen Airport | 24-hr check-in
Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

OceanViewBalcony • RemoteWorking • Near Multiplaza
➤ Bright ✨ and beautifully decorated apartment with ocean views 🌅, a private balcony and an unbeatable location📍. 🚶🏻🚶🏻♀️Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes 🧑🏻💻 Ideal for remote workers , desktop, 750 MB internet speed, 100 Up. ➤ Urban Escape - Building Highlights: ★ Gym. ★ 2 Co-Working Spaces with 500 MB internet speed. ★ Pool on the Rooftop Terrace. ➤ Located in San Francisco, Panama City | Rooftop Pool | Explore the city easily | Uber-Friendly

Modern apt ocean view in heart of Panamá yoo tower
Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Yoo Panama, 54th floor, comfortable and cozy.
Beautiful apartment located on the 54th floor of the most luxurious building in Panama. Areas designed by designer Philip Stark. It is 134 square meters, fully furnished, has a bedroom, walk-in closet, full bathroom, open living room and kitchen, half bathroom, terrace, and laundry room. The building is a unique place, with special and luxurious communal areas; 2 elegant restaurants; 2 swimming pools; gym; spa; 2 squash courts; poker room, lobby with pool table, etc.

New apartment in the heart of Panama
Comfort, location and tranquility in new accommodation, in the financial center of Panama, close to Calle 50 and the emblematic El Tornillo building. All modern amenities, close to hotels, casinos, restaurants and with a completely safe area to walk. Swimming pool and gym on the top floor with spectacular city views. Easy access: from the airport Metro or land terminal you can reach the station via Argentina located 400 meters from the apartment.

Luxury apartment in downtown Panama, banking area
We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

k*| Delightful 1 BR w/King Bed in Calle 50
Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Beautiful apartment in Casco Viejo ST. George D
Welcome to our spacious and charming apartment in Casco Viejo. Located in a vibrant and historic neighborhood. You will love the warm atmosphere created by the lime and pebble walls, in perfect harmony with our modern and elegant decor. The space is large and comfortable, ideal for relaxing after a day exploring the city. As a host, I'm available 24/7 to answer questions and make sure you make the most of your stay.

Full apartment in Panama
This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM
Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Corcho rooms #1 - queen rom with a balcony
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.
Popular amenities for Panama City family-friendly rentals
Family-friendly home rentals with a hot tub

Luxury 2BR w/Ocean Views – 27th Fl, Wanders YOO

Beautiful colonial condo with a hot tub and balcony

PH Yoo 44i – Ocean View Apartment

New Flat with Ocean + City Views

Unique Historic House in Casco

Tropical Paradise at Playa Bonita

Panama Dream View Escape

Luxury apartment in the Panamá city
Family- and pet-friendly home rentals

Arcoiris - Studio in Casco Antiguo

Cozy apartment in Panama

Luxury Centric 2BR Apartment in Casco Viejo

Spacious oceanfront apartment

Where I'm happy in Panama City

Amazing loft with an iconic view of Casco Viejo

Beautiful and Quiet Apartment in the Best Location

private ocean view studio apto.
Family-friendly home rentals with a pool

A Modern & Cozy Apartment In Prime Location

Elegant Apt in Costa del Este. Premium Amenities

Elegant apartment with a view & the warmth of home

Cozy Studio in Cinta Costera with Home Vibes

Cozy Condo with Ocean View in Exclusive Area!

1bd/2Bthrm East Coast-Panama

UrbanLuxuryintheCloudsFreeParkingclosetoeverything

Sea View in Panama City: BrisaMarina
Quick stats about holiday rentals that are family-friendly in Panama City

Total holiday rentals
Explore 1,530 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at £7 per night before taxes and fees

Verified guest reviews
Over 46,180 verified reviews to help you choose

Pet-friendly holiday rentals
Find 630 rentals that welcome pets

Holiday rentals with a pool
910 properties feature pools

Rentals with dedicated workspaces
970 properties have a dedicated workspace

Wifi availability
1,460 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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