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Family-friendly holiday rentals in Panama City

Find and book unique family-friendly homes on Airbnb

Top-rated family-friendly rentals in Panama City

Guests agree: these family-friendly homes are highly rated for location, cleanliness and more.

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Top guest favourite
Flat in Panamá
4.98 out of 5 average rating, 228 reviews

In the heart of Casco, refurbished and with parking

Escape and discover the old town in this remodeled, comfortable and central accommodation in the heart of Casco Viejo. Our location is the best, it will make you come back. Close to restaurants, bars, impressive churches, and museums. The property dates back to the 17th century (1756) history and good atmosphere. You can explore the area on foot, fully equipped kitchen, European king bed, you will feel right at home, surrounded by the famous calicanto walls. -A large living room -Fully-equiped kitchen

Guest favourite
Flat in Panamá
4.93 out of 5 average rating, 101 reviews

Apto 4 min from Tocumen Airport | 24-hr check-in

Layover in Panama? Stay where everything is easy and comfortable Just 4 minutes from Tocumen International Airport – perfect for early flights or quick stopovers A modern, comfortable, and secure apartment with: • Fast WiFi and air conditioning • Smart lock and flexible check-in • 24/7 security • Pool, gym, and fully equipped kitchen • Steps from the ITSE Metro station Ideal for layover travelers, curious tourists, or business trips. 🌴 Just arrive — everything’s ready for you. We’ll be waiting!

Guest favourite
A spacious balcony offers a view of greenery and the sea. A sleek white chair and a small black table are positioned to take in the scenery. A decorative plant enhances the outdoor space, while a modern vase with flowers adds a touch of elegance.
Flat in Panamá
4.97 out of 5 average rating, 33 reviews

OceanViewBalcony • RemoteWorking • Near Multiplaza

➤ Bright ✨ and beautifully decorated apartment with ocean views 🌅, a private balcony and an unbeatable location📍. 🚶🏻🚶🏻‍♀️Walk 5-10 mins to Restaurants, Supermarkets, Multiplaza Mall, Cafes 🧑🏻‍💻 Ideal for remote workers , desktop, 750 MB internet speed, 100 Up. ➤ Urban Escape - Building Highlights: ★ Gym. ★ 2 Co-Working Spaces with 500 MB internet speed. ★ Pool on the Rooftop Terrace. ➤ Located in San Francisco, Panama City | Rooftop Pool | Explore the city easily | Uber-Friendly

Top guest favourite
A modern living area features a large wave mural that enhances the space's vibrant decor. Comfortable seating arrangements include a sleek white sofa and a pair of stylish armchairs. A glass coffee table is centered among the furnishings, with tastefully arranged decorative accents.
Flat in Panamá
4.93 out of 5 average rating, 286 reviews

Modern apt ocean view in heart of Panamá yoo tower

Este lugar tiene una ubicación estratégica: ¡será muy fácil planear tu visita! Ph Yoo and Arts, ubicado en Av. Balboa, súper céntrico Esta hermosa y moderna propiedad cuenta con un estilo único y una vista al mar increíble, piso alto, 2 habitaciones, 2.5 baños completos, Lavanderia, amplia terraza, luces dimeables en todo el espacio, sala comedor, sala de películas, espacio de trabajo, 3 smart tvs, 3 aires acondicionados céntrales, cocina full equipada, cristalería moderna.

Superhost
Flat in Panamá
4.89 out of 5 average rating, 196 reviews

Yoo Panama, 54th floor, comfortable and cozy.

Beautiful apartment located on the 54th floor of the most luxurious building in Panama. Areas designed by designer Philip Stark. It is 134 square meters, fully furnished, has a bedroom, walk-in closet, full bathroom, open living room and kitchen, half bathroom, terrace, and laundry room. The building is a unique place, with special and luxurious communal areas; 2 elegant restaurants; 2 swimming pools; gym; spa; 2 squash courts; poker room, lobby with pool table, etc.

Top guest favourite
A modern living space features a light-colored sofa facing a wall-mounted television. A round dining table with four chairs is positioned nearby. Large windows offer views of the cityscape, while natural light brightens the room. The elegant flooring complements the contemporary design.
Flat in Obarrio
4.96 out of 5 average rating, 25 reviews

New apartment in the heart of Panama

Comfort, location and tranquility in new accommodation, in the financial center of Panama, close to Calle 50 and the emblematic El Tornillo building. All modern amenities, close to hotels, casinos, restaurants and with a completely safe area to walk. Swimming pool and gym on the top floor with spectacular city views. Easy access: from the airport Metro or land terminal you can reach the station via Argentina located 400 meters from the apartment.

Superhost
An inviting living area is featured, showcasing a modern grey sofa accented with decorative pillows. A round glass dining table is surrounded by chairs, and artistic wall frames complement the space. Natural light is filtered through elegantly layered window shades.
Flat in Panamá
4.93 out of 5 average rating, 136 reviews

Luxury apartment in downtown Panama, banking area

We have a strategic location right on the main road of Panama (Calle 50) Bella Vista. You will find yourself located in the heart of the banking area. Whether you're coming for work or vacation, this is the ideal place. You'll find all kinds of restaurants, shops, and shopping malls nearby. You'll have the Cinta Costera just a 10-minute walk away where you can walk or exercise. Fun and enjoyment within walking distance

Guest favourite
A modern dining area features a white table set for four, surrounded by stylish chairs. Large windows allow natural light to fill the space, revealing views of the city skyline. A sleek kitchen is visible in the background, showcasing a gas stove and granite countertops.
Flat in Panamá
4.94 out of 5 average rating, 114 reviews

k*| Delightful 1 BR w/King Bed in Calle 50

Calle 50 es el Times Square de la Ciudad de Panamá. Esta emblemática calle resguarda a la concurrida Area Bancaria. La ubicación del apartamento es excepcional y céntrica, cercana a: ->Estación Iglesia del Carmen [Línea 1 del Metro de Panamá] ->Cinta Costera ->Parque Urracá ->Supermercado Rey ->F&F Tower (Edificio del "Tornillo") ->Nightlife en Calle Uruguay Desde el piso 19 se ofrecen vistas a la ciudad y a la selva.

Guest favourite
A rooftop terrace features a wooden hot tub surrounded by potted plants and a stone pathway. In the background, historical ruins are visible, complementing the vibrant atmosphere of the area. Seating areas and greenery contribute to a relaxing outdoor space.
Flat in Panamá
4.94 out of 5 average rating, 100 reviews

Beautiful apartment in Casco Viejo ST. George D

Welcome to our spacious and charming apartment in Casco Viejo. Located in a vibrant and historic neighborhood. You will love the warm atmosphere created by the lime and pebble walls, in perfect harmony with our modern and elegant decor. The space is large and comfortable, ideal for relaxing after a day exploring the city. As a host, I'm available 24/7 to answer questions and make sure you make the most of your stay.

Guest favourite
Flat in Panamá
4.99 out of 5 average rating, 136 reviews

Full apartment in Panama

This charming apartment is located in one of the best neighborhoods in Panama, San Francisco, a downtown location where you will find ample cuisine, entertainment venues, close to bus stations, and the city's most important shopping mall, Multiplaza. This central and quiet apartment is an opportunity you won't want to miss. It offers the perfect combination of comfort, beauty, and a convenient location.

Top guest favourite
A serene rooftop infinity pool reflects city lights and the night sky. The panoramic view captures the skyline of Ciudad de Panamá, showcasing tall buildings illuminated against the dark water, creating a calm atmosphere for relaxation.
Flat in Panamá
4.99 out of 5 average rating, 131 reviews

Sky Lounge/ APT 1 BR-vista al Mar/Pool bar & GYM

Moderno apartamento de lujo en la Cinta Costera, ideal para ejecutivos, parejas o familias. Dormitorio amplio con vista al mar, baño privado, cocina y electrodomésticos. Diseño elegante con seguridad 24/7, gimnasio, piscinas, 4 restaurantes, bar y Sky Lounge. Ubicación privilegiada cerca de supermercados y excelente oferta gastronómica en Ciudad de Panamá. PANAMA

Superhost
A private balcony features woven chairs and a glass-topped table. Green ferns are visible hanging from the wall, while the tiled roof of nearby buildings adds a traditional touch to the view.
Loft in Panamá
4.87 out of 5 average rating, 192 reviews

Corcho rooms #1 - queen rom with a balcony

Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

Popular amenities for Panama City family-friendly rentals

Quick stats about holiday rentals that are family-friendly in Panama City

  • Total holiday rentals

    Explore 1,530 holiday rentals in Panama City

  • Nightly prices starting at

    Panama City holiday rentals start at £7 per night before taxes and fees

  • Verified guest reviews

    Over 46,180 verified reviews to help you choose

  • Pet-friendly holiday rentals

    Find 630 rentals that welcome pets

  • Holiday rentals with a pool

    910 properties feature pools

  • Rentals with dedicated workspaces

    970 properties have a dedicated workspace

  • Wifi availability

    1,460 of Panama City holiday rentals include wifi access

  • Popular amenities for guests

    Guests love Kitchen, Wifi and Pool across Panama City rentals

  • 4.7 Average rating

    Panama City stays receive an average rating of 4.7 out of 5 from guests

  • Nearby attractions

    Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)

Destinations to explore