Villa holiday rentals in Panama City

Find and book unique villas on Airbnb

Top-rated villa rentals in Panama City

Guests agree: these villas are highly rated for location, cleanliness and more.

0 of 0 items showing

1 of 3 pages

Superhost

Villa in Panamá

4.79 out of 5 average rating, 24 reviews

Spacious Mountain Getaway in Paradise Cloud Forest

Private Villa located at Chagres National Park; a rainforest reserve only 30 minutes away from the airport and 50 minutes from Panama City. At 1,007 meters altitude, you will enjoy the perfect climate, bird watching, beautiful river walks, waterfalls, and many hiking trails full of wildlife, enjoy our mountain's pure air or simply relax in Nature. Bring the whole family to this great place with lots of room for fun. Bring your pets our land is completely fenced, they can run free in a vast space

Guest favourite

Villa in Chame District

4.85 out of 5 average rating, 227 reviews

Surf Relax Play Pacific Ocean View Villa

White sand, surf-able waves, or just a comfortable chill vibe to enjoy the tropical weather of Panama. Playa Caracol is about an hour and 10 minutes drive from the city. This spacious, 2 bedroom, 2 bath villa with it's Pacific Ocean front location is the perfect place for you to enjoy an unforgettable family vacation. Walk out to the beach just steps from the villa, swim in the pool next to this villa or enjoy the resort pools and amenities. Or hike the nearby mountains with a local guide. PET

Top guest favourite

Villa in Punta Pacifica

5 out of 5 average rating, 21 reviews

5BR House in Panama City w/ Pool & King Beds

Enjoy a family or friends' getaway in this modern, newly remodeled house. This property boasts 5 bedrooms, 4.5 bathrooms, 10 beds, and can comfortably accommodate up to 15 guests. The house also features a private outdoor pool, where you can soak up the sun and cool off on hot days, all while being in a central location, just meters away from malls, supermarkets and night life. It's fully furnished with everything you could possibly need to ensure your stay is as comfortable as possible.

Villa

4.77 out of 5 average rating, 13 reviews

Casa Laguna - luxury beach front house with pool

Welcome to our little piece of paradise - Casa Laguna! The house - newly renovated in 2022 - sits right by the private-feel beach Playa Encanto on the beautiful island Saboga, Las Perlas Islands. The house features a large pool and jacuzzi, multiple terraces and a stunning beach and sunset view. The open concept house offers 3 double and one twin bedroom all with en-suite bathrooms and a lavish living room and kitchen. The highlight are the outdoor areas, the gym and the beach access.

Guest favourite

Villa in Punta Chame

4.9 out of 5 average rating, 31 reviews

Punta Chame Beachfront Villa — 5BR + Pool

Escape to paradise at Villa Las Palmeras, a tropical getaway in Punta Chame, perfect for groups, families, or special celebrations. This 5-bedroom villa features a private pool, BBQ area, rooftop with 360° views, and beach access just steps away. It’s designed for sharing unforgettable moments surrounded by nature. Located less than 2 hours from Panama City and just a 5-minute walk to the beach, Villa Las Palmeras offers privacy, comfort, and a laid-back atmosphere in a stunning setting.

Guest favourite

Villa in Panamá

4.96 out of 5 average rating, 57 reviews

Breathtaking Views Mansion w/King Beds

Book your next thrilling Panama City vacation at our dreamy 11,500 sq. foot multi-story family mansion, superbly located on a hilltop high above the metropolis in this affluent neighborhood. Ideal for longer stays. Discover the vibrant buzz of Cinta Costera or explore the UNESCO world heritage sites at Casco Viejo – all under 5 km away from your doorstep. Enjoy a refreshing dip into the swimming pool and admire the sublime views of the Panama City Skyline from our unique roof terrace.

Superhost

Villa in Chame

4.84 out of 5 average rating, 102 reviews

Ocean front Villa (C5-1C) 2 bed, 2 bath

Unique Villa steps away from the ocean and fully furnished ground floor unit 2 bed/2 bath apt has an open concept living, dining & kitchen space with sofa bed (6 guests). This is a unique villa apartment over looking the picturesque Playa Caracol coast with ocean front and majestic mountain views. Playa Caracol is located on the beach of Chame and is a newly developed area with expansion for the property and amenities. 1km of beach to offer you the best beach experience around.

Guest favourite

Villa in Portobelo

5 out of 5 average rating, 70 reviews

Entire Villa with pool in front of beach!

Beautiful spacious 4 bedroom villa right in front of the sea. Enjoy the swimming pool with your family, then take a dip into the sea only steps away. Very pet friendly! Take a boat trip for the day with a local certified tour guide from portobelo town. Every room has full AC, including the living room - but please be conscious of the environment when using ACs. Excellent WiFi ! Open Kitchen, with breakfast included. We can also arrange for lunch - fresh lobster!

Top guest favourite

Villa in Punta Chame

4.97 out of 5 average rating, 127 reviews

Beach House with Pool/Gazebo in Punta Chame!

"Disconnect from the routine and enjoy a sunny environment. Just breathe fresh air in a different surroundings. Enjoy a few days in the pool, relaxed in a hammock and of course steps from a spectacular beach with views of the city and islands. The house has 4 bedrooms, 3.5 bathrooms, electric plant and all the facilities to enjoy and rest. Close to restaurants and the best beach to do and see kitesurfing adventures, fish, SUP, etc. Only 90 minutes from the city"

Guest favourite

Villa in Chame District

4.96 out of 5 average rating, 28 reviews

Villa Playa Caracol, 3 Bedrooms, Pet Friendly

¡Welcome to your perfect beach getaway! This charming ground-floor villa awaits you just 100 meters from the golden sand and refreshing waves of the sea. This home offers an ideal retreat for families and groups of friends looking to relax and enjoy the sun and sea breeze. Enjoy the pool right in front of the villa, where you'll also find a playground for everyone to enjoy. ¡Book now and experience a dreamy seaside vacation!

Superhost

Villa in Mechi

4.6 out of 5 average rating, 15 reviews

Caribbean Beach House with Pool

Perfect location for family gatherings in a gated community , 24 hour security , beautiful villa with Pool . 200 meters from beach. Located one hour , 15 minutes away from international Airport . Located 50 minutes away from Portobelo. 5 minute drive from playa Angosta and twenty five minutes away from Isle Grande. Minutes away from the best scuba diving excursions on the Caribbean coast.

Top guest favourite

Villa in Panamá

5 out of 5 average rating, 13 reviews

Villa Helena Studio 1 Apt Cerro Azul

One bedroom cottage with private kitchen and bathroom in a peaceful compound with shared pool. Internet and free parking available. Laundry facilities available for longer stays. Cook your own meals, or have me cook some authentic Caribbean dishes like curries, or use the restaurant available next door. Surrounded by nature and access to trails, waterfalls, rivers, swimming holes.