
Loft holiday rentals in Panama City
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Top-rated loft rentals in Panama City
Guests agree: these loft rentals are highly rated for location, cleanliness and more.

“Mi Casita de Azúcar" Best Location Romantic Loft
Mi casita de Azúcar is a beautiful renovated 1 bedroom loft with plenty of Romance! With everything new, it is located in the Heart of the UNESCO World Heritage Old Town. In front of the Great Plaza Mayor, BEST LOCATION in the area. Very close to restaurants, shops and bars. Shares the square with the Panama Metropolitan Cathedral 1688, the Interoceanic Museum, the Municipal Palace of 1910 and the Central Hotel. It has partial view of the Plaza and the sea, in a Presidential Palace street.

Modern apartment 20 minutes from the airport
Comfortable and cozy apartment on Av. la Pulida, 8 minutes from the Cincuentenario metro station. For business travelers and couples, this apartment features a bedroom with a full bed, a TV in the room, a full bathroom with hot water, a fully equipped kitchen, a living-dining room, a Smart TV, air conditioning, a laundry room, and a closet. It's just 8 minutes from the metro station and offers easy access to any point in the city. Centrally located, yet quiet. Enjoy a perfect stay!

★Large & Sunny SUITE in Historic District★
!!! NEW LISTING !!! !!! NEW LISTING !!! NEW LISTING !!! Spacious penthouse suite set into the rustic Calicanto stonewalls, finished with wooden details and beautiful artworks by various emerging artists. The suite is contemporary in style, kitted out with state of the art bathroom and kitchen, king-sized beds and private balcony with fabulous views. The suite has 1 tv per bedroom and strong wifi for work remotely!! ★Everything you need for your panama experience★

Patty’s Casco 2BR Loft | Balcony & Personal Touch
“Feel at home in Casco Viejo—personally welcomed by your hosts, Patty & Rudy.” Stay in the Heart of Casco Viejo with Patty’s Casitas! Prime Casco Viejo Location | Quiet, Convenient & Charming Stay steps from restaurants, cafés, bars, and plazas—right by the El Rey boutique supermarket and the waterfront promenade. This peaceful spot is rare in Casco, tucked away from rooftop noise and perfectly located at the entrance of the neighborhood for easy in & out access!

Modern 2BR/2BA Loft Steps from Casco Viejo
Modern loft ubicado en Casa Korsi, mucho más que un alojamiento: una experiencia de diseño y autenticidad en el corazón de Santa Ana, a pasos del Casco Viejo. Su ubicación privilegiada permite explorar caminando restaurantes, bares, plazas y la vibrante vida cultural de la Ciudad de Panamá. Combina confort moderno con esencia local, ideal para turismo o trabajo remoto. Perfecto para quienes buscan estilo, ubicación estratégica y una estadía auténtica.

Loft 3b Old Town Best! It's 150 m2 (492 feet)
Immerse yourself in the historic charm and modern elegance of our 3-bedroom, 150 m2 loft in the heart of the Old Town. With wooden floors that radiate warmth and a modern open-plan kitchen ideal for sharing, this space guarantees a memorable vacation. Located on Avenida A, you'll find yourself just a few steps away from exquisite restaurants, museums, colonial churches, and the Casco's coveted rooftops, making every day an adventure.

The Urban Loft #206 | La Résidence Panamá
Contemporary comfort for the modern traveler. This 69-71 m² suite includes 2 bedrooms (king and queen bed), sofa, 2 bathrooms, full kitchen, washer/dryer, coffee machine, and A/C — everything you need to feel at home. At LA RÉSIDENCE, we offer more than just a stay — we deliver a complete experience. With a blend of modern design, central location, and thoughtful amenities, we create a space built for your comfort and productivity.

Casco Viejo Dream Loft – Cozy & Central 1BR Apt
Enjoy a unique experience, in this elegant and centrally-located loft. Fully remodeled 1 bedroom apartment, in a central location in Casco Viejo (the old city). You will be just steps away from many restaurants, cafes, museums, and the existing night life casco has to offer. Located in “Casa Neuman",” this restored- colonial building and features unique crafted wall décor, as well as some of the original "calicanto" walls.

Loft Studio | Design By Paradox
PRIVATE APARTMENT IN PANAMA CITY, CLOSE TO CASCO VIEJO. If you're looking to get submerged into real Panama and live among the real locals. This is the right place to be. For More Info or visual content, follow us on IG as Paradox Experience and visit our Virtual Showcase with the link in our IG BIO. More than a regular stay, we are an experience.

español
Relax with the whole family or friends in this peaceful place in Panama City, just 10 minutes from Tocumen Airport, close to main roads, you can take the metro, bus or taxi service easily and quickly to visit Panama City, close to MetroMall and Los Pueblos shopping center. A super cool apartment... we're sure you'll love the breeze in this place.

Corcho rooms #1 - queen rom with a balcony
Enjoy charming “Corcho rooms” in the heart of touristic Casco Viejo district of Panama City. We carefully restored old colonial building and converted it to the restaurant and apartments upstairs. “Corcho” is luckily situated in the central, restored part of Casco. Most of the buildings around are restored and the neighborhood is safe.

Canal Loft
Apartment on 1st floor, ideal for couples who love good taste, tranquility and comfort. Nearby to the apartment there are trails to the Panama Canal, hills and jungle. Apartment on the 1st Floor, ideal for couples who love good taste, tranquility and comfort. Near the apartment there are trails to the Panama Canal, hills and jungle.
Popular amenities for loft rentals in Panama City
Family-friendly loft rentals

Modern 2BR/2BA Loft Steps from Casco Viejo

Patty’s Casco 2BR Loft | Balcony & Personal Touch

Studio in El Cangrejo. Steps to Via Argentina

Amazing Loft with the Best view of Casco viejo!

Casco Viejo Dream Loft – Cozy & Central 1BR Apt

Modern apartment 20 minutes from the airport

Loft 3b Old Town Best! It's 150 m2 (492 feet)

Loft Studio | Design By Paradox
Loft rentals with a washing machine and dryer

ideal rooftop & pool family break

Loft encantador despertar frente al mar

The Urban Loft #204 | La Résidence Panamá

Castellana Loft By AcoModo @ Casco Viejo

★ Aparment for Executives VIP ★ Full Kitchen ★

loft with lots of peace, quiet and elegance

City Maisonette

The Urban Loft #205 | La Résidence Panamá
Monthly loft rentals

español

LoftModernoPrivado-A/A-Wifi/Netflix Free

Comfortable room with a nice view

StudioModerno+Privado+chanis+Wifi+Kitchen+Centrico
Quick stats about loft rentals in Panama City

Total holiday rentals
Explore 50 holiday rentals in Panama City

Nightly prices starting at
Panama City holiday rentals start at £15 per night before taxes and fees

Verified guest reviews
Over 2,320 verified reviews to help you choose

Family-friendly holiday rentals
10 properties offer extra space & child-friendly amenities

Holiday rentals with a pool
10 properties feature pools

Rentals with dedicated workspaces
30 properties have a dedicated workspace

Wifi availability
50 of Panama City holiday rentals include wifi access

Popular amenities for guests
Guests love Kitchen, Wifi and Pool across Panama City rentals

4.7 Average rating
Panama City stays receive an average rating of 4.7 out of 5 from guests

Nearby attractions
Panama City’s top spots include Miraflores Locks, Museo de Arte Contemporáneo and Santo Tomas (Panama Metro)
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